Gene Page:HHLA1

Summary?
GeneID 10086
Symbol HHLA1
Synonyms PLA2L
Description HERV-H LTR-associating 1
Reference MIM:604109|HGNC:HGNC:4904|Ensembl:ENSG00000132297|HPRD:06823|
Gene type protein-coding
Map location 8q24
Pascal p-value 0.031

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
BHLHE41 0.61 0.61
TCFL5 0.61 0.52
CBR1 0.58 0.62
APOD 0.58 0.61
CD74 0.56 0.63
IL17D 0.56 0.55
CEBPB 0.56 0.54
HSPB8 0.56 0.63
HLA-DRB1 0.56 0.59
CYS1 0.55 0.53
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
NKIRAS2 -0.40 -0.41
TUBB2B -0.39 -0.47
ZBTB8A -0.39 -0.38
YBX1 -0.39 -0.46
KIAA1949 -0.39 -0.41
IGF2BP3 -0.39 -0.48
IDH1 -0.38 -0.44
ZNF286 -0.38 -0.38
FNBP1L -0.38 -0.38
HMGB3 -0.38 -0.41

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
BROCKE APOPTOSIS REVERSED BY IL6 144 98 All SZGR 2.0 genes in this pathway
CHEOK RESPONSE TO HD MTX UP 23 13 All SZGR 2.0 genes in this pathway
ASTIER INTEGRIN SIGNALING 59 44 All SZGR 2.0 genes in this pathway
KIM GASTRIC CANCER CHEMOSENSITIVITY 103 64 All SZGR 2.0 genes in this pathway
CROMER TUMORIGENESIS UP 63 36 All SZGR 2.0 genes in this pathway