Gene Page:TRIM10

Summary?
GeneID 10107
Symbol TRIM10
Synonyms HERF1|RFB30|RNF9
Description tripartite motif containing 10
Reference MIM:605701|HGNC:HGNC:10072|Ensembl:ENSG00000204613|HPRD:05752|Vega:OTTHUMG00000031295
Gene type protein-coding
Map location 6p21.3
Pascal p-value 1E-12
Fetal beta -0.242

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
PMID:cooccur High-throughput literature-search 系统的搜索PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
GSMA_I Genome scan meta-analysis Psr: 0.033
Literature High-throughput literature-search Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias Click to show details

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
CREB3L1 0.69 0.73
SUOX 0.69 0.65
ADCY2 0.68 0.70
CCDC3 0.68 0.72
CCKBR 0.66 0.69
SERPINE2 0.65 0.67
ETV5 0.65 0.71
OLFML2B 0.64 0.70
CHRM1 0.64 0.68
ZDHHC8 0.64 0.64
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
C21orf57 -0.46 -0.45
FAM159B -0.45 -0.50
EIF5B -0.41 -0.39
RP9P -0.38 -0.39
AL050337.1 -0.38 -0.28
AC011475.1 -0.38 -0.35
CWF19L2 -0.38 -0.33
AC098691.2 -0.38 -0.27
RBMX2 -0.36 -0.34
NSBP1 -0.36 -0.32

Section III. Gene Ontology annotation

Molecular function 去的术语 Evidence Neuro keywords PubMed ID
GO:0005515 protein binding IEA -
GO:0008270 zinc ion binding IEA -
GO:0008270 zinc ion binding NAS -
GO:0046872 metal ion binding IEA -
Biological process 去的术语 Evidence Neuro keywords PubMed ID
GO:0030097 hemopoiesis NAS -
Cellular component 去的术语 Evidence Neuro keywords PubMed ID
GO:0005622 intracellular IEA -
GO:0005622 intracellular NAS -
GO:0005737 cytoplasm IEA -

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
INGRAM SHH TARGETS UP 127 79 All SZGR 2.0 genes in this pathway
LEE AGING NEOCORTEX DN 80 49 All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE UP 1691 1088 All SZGR 2.0 genes in this pathway
VALK AML CLUSTER 7 28 16 All SZGR 2.0 genes in this pathway
MIKKELSEN ES ICP WITH H3K4ME3 718 401 All SZGR 2.0 genes in this pathway
CHYLA CBFA2T3 TARGETS DN 242 146 All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS UP 504 321 All SZGR 2.0 genes in this pathway
TORCHIA TARGETS OF EWSR1 FLI1 FUSION UP 271 165 All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family Target position miRNA ID miRNA seq
UTR start UTR end Match method
miR-7 104 110 1A hsa-miR-7SZ UGGAAGACUAGUGAUUUUGUUG