Gene Page:DSCR4
Summary?
| GeneID | 10281 |
| Symbol | DSCR4 |
| Synonyms | DCRB|DSCRB |
| Description | Down syndrome critical region 4 |
| Reference | MIM:604829|HGNC:HGNC:3045|Ensembl:ENSG00000184029|HPRD:05318|Vega:OTTHUMG00000086673 |
| Gene type | protein-coding |
| Map location | 21q22.2 |
| Pascal p-value | 0.044 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26conception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| GNL2 | 0.93 | 0.92 |
| HNRNPA2B1 | 0.91 | 0.91 |
| CXorf26 | 0.91 | 0.93 |
| IK | 0.91 | 0.93 |
| RIOK1 | 0.90 | 0.92 |
| CBX3 | 0.90 | 0.93 |
| C9orf30 | 0.90 | 0.91 |
| HTATSF1 | 0.90 | 0.92 |
| RARS2 | 0.90 | 0.91 |
| SNW1 | 0.90 | 0.92 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| HLA-F | -0.73 | -0.81 |
| AF347015.27 | -0.71 | -0.83 |
| MT-CO2 | -0.71 | -0.83 |
| AF347015.33 | -0.70 | -0.83 |
| AF347015.31 | -0.70 | -0.83 |
| TINAGL1 | -0.69 | -0.80 |
| MT-CYB | -0.68 | -0.82 |
| TSC22D4 | -0.68 | -0.79 |
| FXYD1 | -0.68 | -0.81 |
| AF347015.8 | -0.67 | -0.82 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| JAZAG TGFB1 SIGNALING UP | 108 | 69 | All SZGR 2.0 genes in this pathway |
| PUJANA ATM PCC NETWORK | 1442 | 892 | All SZGR 2.0 genes in this pathway |