Gene Page:PRG3
Summary?
| GeneID | 10394 |
| Symbol | PRG3 |
| Synonyms | MBP2|MBPH |
| Description | 蛋白多糖3 |
| Reference | MIM:606814|HGNC:HGNC:9363|Ensembl:ENSG00000156575|HPRD:08434|Vega:OTTHUMG00000167026 |
| Gene type | protein-coding |
| Map location | 11q12 |
| Pascal p-value | 6.834E-4 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
某羊乳酪l (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| CNTLN | 0.78 | 0.49 |
| NDC80 | 0.76 | 0.36 |
| HMGB2 | 0.76 | 0.53 |
| C20orf72 | 0.76 | 0.50 |
| TRIP10 | 0.76 | 0.57 |
| ARHGAP11A | 0.76 | 0.43 |
| DLGAP5 | 0.75 | 0.34 |
| NUF2 | 0.75 | 0.41 |
| ACTL6A | 0.75 | 0.52 |
| CEP55 | 0.75 | 0.36 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| LEPREL2 | -0.47 | -0.53 |
| TPST2 | -0.47 | -0.54 |
| ACOT4 | -0.46 | -0.55 |
| FXYD7 | -0.46 | -0.51 |
| NBL1 | -0.46 | -0.49 |
| MATK | -0.46 | -0.55 |
| ADAP1 | -0.46 | -0.47 |
| RTBDN | -0.45 | -0.58 |
| EPB49 | -0.45 | -0.50 |
| TMEM59L | -0.45 | -0.52 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| TAKEDA TARGETS OF NUP98 HOXA9 FUSION 3D DN | 31 | 19 | All SZGR 2.0 genes in this pathway |
| DARWICHE SKIN TUMOR PROMOTER UP | 142 | 96 | All SZGR 2.0 genes in this pathway |
| DARWICHE PAPILLOMA RISK LOW UP | 162 | 104 | All SZGR 2.0 genes in this pathway |
| DARWICHE PAPILLOMA RISK HIGH UP | 147 | 101 | All SZGR 2.0 genes in this pathway |
| DARWICHE SQUAMOUS CELL CARCINOMA UP | 146 | 104 | All SZGR 2.0 genes in this pathway |
| BYSTROEM CORRELATED WITH IL5 UP | 51 | 30 | All SZGR 2.0 genes in this pathway |
| ALCALAY AML BY NPM1 LOCALIZATION DN | 184 | 132 | All SZGR 2.0 genes in this pathway |
| LIAN NEUTROPHIL GRANULE CONSTITUENTS | 25 | 13 | All SZGR 2.0 genes in this pathway |
| KUMAR TARGETS OF MLL AF9 FUSION | 405 | 264 | All SZGR 2.0 genes in this pathway |
| CHYLA CBFA2T3 TARGETS UP | 387 | 225 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY | 1839 | 928 | All SZGR 2.0 genes in this pathway |
| NABA PROTEOGLYCANS | 35 | 23 | All SZGR 2.0 genes in this pathway |
| NABA CORE MATRISOME | 275 | 148 | All SZGR 2.0 genes in this pathway |
| NABA MATRISOME | 1028 | 559 | All SZGR 2.0 genes in this pathway |