Summary
基因 10492
象征 SYNCRIP
Synonyms GRY-RBP|GRYRBP|HNRNPQ|HNRPQ1|NSAP1|PP68|hnRNP-Q
Description Synaptotagmin结合,细胞质RNA相互作用蛋白
Reference MIM:616686|HGNC:HGNC:16918|Ensembl:ENSG00000135316|HPRD:06734|Vega:Otthumg0000000015141
基因类型 蛋白质编码
Map location 6q14-q15
Pascal p-value 1.459E-4
Sherlock p-value 0.467
主持人 Cerebellar Hemisphere

Gene in Data Sources
基因集名称 Method of gene set Description 信息
CV:PGCnp Genome-wide Association Study GWAS

Section I. Genetics and epigenetics annotation


第二节。转录组注释

一般基因表达(GTEX)

Not available

时间变化的基因表达(brainspan)

Footnote:
SC:分皮质区域;SM:感觉运动区域s; FC: frontal cortex; and TP: temporal-parietal cortex
ST1:胎儿(13-26个概念后周),ST2:婴儿早期至童年(4个月至11年)和ST3:青春期至成年期(13-23年)
所示的栏表示表达分布的较低25%和上层25%。

No co-expressed genes in brain regions


第三节。基因本体论注释

分子功能 去学期 证据 神经关键字 PubMed ID
去:0000166 nucleotide binding IEA -
GO:0003723 RNA结合 TAS 9847309
去:0005515 蛋白质结合 IPI 12674497|17353931
GO:0008143 聚(a)结合 IEA -
生物过程 去学期 证据 神经关键字 PubMed ID
GO:0006397 mRNA processing IEA -
GO:0008380 RNA剪接 TAS 9847309
GO:0044419 interspecies interaction between organisms IEA -
Cellular component 去学期 证据 神经关键字 PubMed ID
去:0005792 microsome IEA -
去:0005634 nucleus TAS 9847309
去:0005681 剪接体 IEA -
去:0005737 cytoplasm IEA -
去:0005783 内质网 IEA -

Section IV. Protein-protein interaction annotation

互动者 别名b 官方全名b 实验 Source PubMed ID
A1CF ACF |ACF64 |ACF65 |apobec1cf |ASP |MGC163391 |RP11-564C4.2 APOBEC1 complementation factor - HPRD,BioGRID 11134005|11352648
APOBEC1 apobec-1 |床|CDAR1 |HEPR apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 重构的复合物
Two-hybrid
Biogrid 11352648
CNBP CNBP1 |DM2 |FLJ11631 |Promm |RNF163 |ZCCHC22 |Znf9 CCHC型锌指,核酸结合蛋白 Affinity Capture-MS Biogrid 17353931
EPRS dkfzp313b047 |耳朵|gluprors |pars |Pig32 |QARS |QPRS glutamyl-prolyl-tRNA synthetase NSAP-1 interacts with GluProRS. 绑定 15479637
gapdh G3PD | GAPD | MGC88685 3-磷酸​​甘油醛脱氢酶 NSAP-1 interacts with GAPDH. 绑定 15479637
GRB2 灰烬|EGFRBP-GRB2 |Grb3-3 |MST084 |MSTP084 生长因子受体结合蛋白2 重构的复合物 Biogrid 9341187
hnrnpab ABBP1 |FLJ40338 |hnrpab 异质核核糖核蛋白A/B - HPRD 11352648
INSR CD220 |HHF5 胰岛素受体 - HPRD,BioGRID 11994298
MGC34774 - 核糖体蛋白L13A假基因 NSAP-1与L13A相互作用。 绑定 15479637
PLCG1 PLC-II |PLC1 |PLC148 |Plcgamma1 磷脂酶C,伽马1 重构的复合物 Biogrid 9341187
PRKRA DYT16 | HSD14 | PACT | RAX 蛋白激酶,干扰素诱导的双链RNA依赖性激活剂 Affinity Capture-MS Biogrid 17353931
PRMT1 ANM1 |HCP1 |HRMT1L2 |IR1B4 蛋白精氨酸甲基转移酶1 生化活动 Biogrid 12183049
PTPN11 bptp3 |CFC |MGC14433 |NS1 |PTP-1D |PTP2C |SH-PTP2 |sh-ptp3 |SHP2 protein tyrosine phosphatase, non-receptor type 11 Two-hybrid Biogrid 9847309
PUF60 FIR | FLJ31379 | RoBPI | SIAHBP1 poly-U结合剪接因子60kDa Affinity Capture-MS Biogrid 17353931
SMN1 BCD541 |SMA |sma1 |sma2 |sma3 |sma4 |sma@ |SMN |SMNT |T-BCD541 survival of motor neuron 1, telomeric - HPRD 11773003
STK24 MST-3 |mst3 |mst3b |Ste20 |STK3 serine/threonine kinase 24 (STE20 homolog, yeast) Affinity Capture-MS Biogrid 17353931
Syt1 DKFZP781D2042 |p65 |SVP65 |Syt synaptotagmin I - HPRD,BioGRID 10734137
SYT11 DKFZP781D015 |KIAA0080 |MGC10881 |MGC17226 |SYT12 Synaptotagmin XI - HPRD 10734137
Syt2 Sytii synaptotagmin II - HPRD,BioGRID 10734137
Syt3 DKFZP761O132 |Sytiii Synaptotagmin III 重构的复合物 Biogrid 10734137
Syt4 HST1192 |KIAA1342 synaptotagmin IV - HPRD,BioGRID 10734137
Syt5 - Synaptotagmin v - HPRD 10734137
Syt7 IPCA-7 | MGC150517 | PCANAP7 | SYT-VII Synaptotagmin VII - HPRD,BioGRID 10734137
Syt8 DKFZp434K0322 Synaptotagmin VIII 亲和力捕获 - 韦斯特恩
重构的复合物
Biogrid 10734137
Syt9 FLJ45896 synaptotagmin IX - HPRD,BioGRID 10734137


Section V. Pathway annotation

路径名 路径大小 # SZGR 2.0 genes in pathway 信息
NAKAMURA CANCER MICROENVIRONMENT DN 46 29 All SZGR 2.0 genes in this pathway
中村肿瘤区周围与中央 285 181 All SZGR 2.0 genes in this pathway
Onken Uveal黑色素瘤 783 507 All SZGR 2.0 genes in this pathway
Davicioni分子臂与ERMS 332 228 All SZGR 2.0 genes in this pathway
SENGUPTA NASOPHARYNGEAL CARCINOMA WITH LMP1 UP 408 247 All SZGR 2.0 genes in this pathway
GARY CD5 TARGETS DN 431 263 All SZGR 2.0 genes in this pathway
OSMAN BLADDER CANCER UP 404 246 All SZGR 2.0 genes in this pathway
Mullighan MLL签名2 DN 281 186 All SZGR 2.0 genes in this pathway
TIEN INTESTINE PROBIOTICS 24HR UP 557 331 All SZGR 2.0 genes in this pathway
KIM WT1 TARGETS 12HR DN 209 122 All SZGR 2.0 genes in this pathway
Graham CML分割与正常静止 181 101 All SZGR 2.0 genes in this pathway
hahtola兄弟姐妹fungoides CD4 DN 116 71 All SZGR 2.0 genes in this pathway
ENK UV响应表皮DN 508 354 All SZGR 2.0 genes in this pathway
阿霉素DN的Graessmann凋亡 1781 1082 All SZGR 2.0 genes in this pathway
Graessmann对MC和阿霉素DN的反应 770 415 All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL BREAST 6 7WK UP 197 135 All SZGR 2.0 genes in this pathway
农民乳腺癌根源与基础 330 217 All SZGR 2.0 genes in this pathway
农民乳腺癌基础与仙女 330 215 All SZGR 2.0 genes in this pathway
SCHLOSSER MYC TARGETS AND SERUM RESPONSE DN 47 34 All SZGR 2.0 genes in this pathway
YANG乳腺癌ESR1激光DN 50 38 All SZGR 2.0 genes in this pathway
PUJANA BRCA1 PCC网络 1652 1023 All SZGR 2.0 genes in this pathway
Pujana ATM PCC网络 1442 892 All SZGR 2.0 genes in this pathway
PUJANA CHEK2 PCC网络 779 480 All SZGR 2.0 genes in this pathway
Nuytten Nipp1靶向 769 437 All SZGR 2.0 genes in this pathway
Ferreira Ewings肉瘤不稳定与稳定 167 92 All SZGR 2.0 genes in this pathway
刘普通癌基因 79 47 All SZGR 2.0 genes in this pathway
带有E盒的WEI MYCN目标 795 478 All SZGR 2.0 genes in this pathway
狮子转移 539 324 All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 6HR UP 176 115 All SZGR 2.0 genes in this pathway
GC期DN的pasqualucci淋巴瘤 165 104 All SZGR 2.0 genes in this pathway
Benporath循环基因 648 385 All SZGR 2.0 genes in this pathway
Mir192和Mir215的Georges目标 893 528 All SZGR 2.0 genes in this pathway
Onder CDH1目标1 DN 169 102 All SZGR 2.0 genes in this pathway
SHEPARD CRUSH AND BURN MUTANT DN 185 111 All SZGR 2.0 genes in this pathway
VANTVEER BREAST CANCER METASTASIS DN 121 65 All SZGR 2.0 genes in this pathway
Flechner PBL肾脏移植OK vs捐助者 151 100 All SZGR 2.0 genes in this pathway
Flechner PBL肾脏移植被拒绝与OK DN 51 35 All SZGR 2.0 genes in this pathway
彭雷帕霉素反应dn 245 154 All SZGR 2.0 genes in this pathway
PENG GLUTAMINE DEPRIVATION DN 337 230 All SZGR 2.0 genes in this pathway
MATSUDA NATURAL KILLER DIFFERENTIATION 475 313 All SZGR 2.0 genes in this pathway
阿尔茨海默氏病dn 1237 837 All SZGR 2.0 genes in this pathway
Hedenfalk乳腺癌BRACX DN 20 14 All SZGR 2.0 genes in this pathway
HU GENOTOXIN ACTION DIRECT VS INDIRECT 24HR 55 38 All SZGR 2.0 genes in this pathway
HU遗传毒性损伤4小时 35 28 All SZGR 2.0 genes in this pathway
Krige对Tosedostat 6小时DN的响应 911 527 All SZGR 2.0 genes in this pathway
Krige对Tosedostat 24小时DN的反应 1011 592 All SZGR 2.0 genes in this pathway
MONNIER POSTRADIATION TUMOR ESCAPE UP 393 244 All SZGR 2.0 genes in this pathway
Smid乳腺癌基础 648 398 All SZGR 2.0 genes in this pathway
ZHANG BREAST CANCER PROGENITORS UP 425 253 All SZGR 2.0 genes in this pathway
级结肠癌 871 505 All SZGR 2.0 genes in this pathway
GRADE COLON AND RECTAL CANCER UP 285 167 All SZGR 2.0 genes in this pathway
对Salirasib dn的Blum响应 342 220 All SZGR 2.0 genes in this pathway
Mueller Plurinet 299 189 All SZGR 2.0 genes in this pathway
Vantveer乳腺癌ESR1 DN 240 153 All SZGR 2.0 genes in this pathway
SHEDDEN LUNG CANCER POOR SURVIVAL A6 456 285 All SZGR 2.0 genes in this pathway
张TLX目标60小时DN 277 166 All SZGR 2.0 genes in this pathway
DORN腺病毒感染12小时DN 33 25 All SZGR 2.0 genes in this pathway
DORN ADENOVIRUS INFECTION 24HR UP 12 6 All SZGR 2.0 genes in this pathway
DORN腺病毒感染32小时DN 39 28 All SZGR 2.0 genes in this pathway
DORN腺病毒感染48小时DN 40 29 All SZGR 2.0 genes in this pathway
YAO对孕酮簇的时间反应14 143 86 All SZGR 2.0 genes in this pathway
惠特菲尔德细胞周期M G1 148 95 All SZGR 2.0 genes in this pathway
Karlsson TGFB1靶向 127 78 All SZGR 2.0 genes in this pathway
HIRSCH CELLULAR TRANSFORMATION SIGNATURE DN 103 67 All SZGR 2.0 genes in this pathway
Johnstone Parvb目标2 DN 336 211 All SZGR 2.0 genes in this pathway
JOHNSTONE PARVB TARGETS 3 DN 918 550 All SZGR 2.0 genes in this pathway
Lee BMP2靶向DN 882 538 All SZGR 2.0 genes in this pathway
ikeda mir1靶向 53 39 All SZGR 2.0 genes in this pathway
SPI1和FLI1 DN的Juban目标 92 60 All SZGR 2.0 genes in this pathway
FORTSCHEGGER PHF8 TARGETS UP 279 155 All SZGR 2.0 genes in this pathway
RAO BOUND BY SALL4 227 149 All SZGR 2.0 genes in this pathway

第六节。microRNA注释

mirna家族 Target position miRNA ID mirna seq
UTR开始 UTR结束 匹配方法
miR-375 139 146 1A,M8 HSA-MIR-375 UUUGUUCGUUCGGCUCGCGUGA
miR-381 365 371 M8 HSA-MIR-381 uauacaagggcaagcucucugu
HSA-MIR-381 uauacaagggcaagcucucugu
miR-382 393 399 1a HSA-MIR-382brain Gaaguuucgugguggauucg