Gene Page:GLRX3
Summary?
| GeneID | 10539 |
| Symbol | GLRX3 |
| Synonyms | GLRX4|GRX3|GRX4|PICOT|TXNL2|TXNL3 |
| Description | glutaredoxin 3 |
| Reference | MIM:612754|HGNC:HGNC:15987|Ensembl:ENSG00000108010|HPRD:10153|Vega:OTTHUMG00000019267 |
| Gene type | protein-coding |
| Map location | 10q26 |
| Pascal p-value | 0.05 |
| eGene | 元 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| GSMA_IIA | Genome scan meta-analysis (All samples) | Psr: 0.03487 |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
某fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| GDA | 0.61 | 0.58 |
| RASGRF2 | 0.60 | 0.51 |
| PRKCB | 0.59 | 0.55 |
| KCNMA1 | 0.59 | 0.54 |
| KIAA1045 | 0.59 | 0.53 |
| IQSEC2 | 0.59 | 0.55 |
| SCN8A | 0.59 | 0.49 |
| ARHGAP26 | 0.59 | 0.51 |
| MAPK9 | 0.58 | 0.56 |
| SGTB | 0.58 | 0.53 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| BCL7C | -0.32 | -0.36 |
| SH2D2A | -0.29 | -0.30 |
| NME4 | -0.29 | -0.34 |
| RPL28 | -0.29 | -0.34 |
| RAB13 | -0.28 | -0.28 |
| RPL18 | -0.28 | -0.31 |
| HYAL2 | -0.28 | -0.27 |
| RPL23A | -0.28 | -0.26 |
| RPL35 | -0.28 | -0.31 |
| RPL36 | -0.28 | -0.32 |
Section III. Gene Ontology annotation
| Molecular function | 去的术语 | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0005515 | protein binding | 新闻学会 | 10636891|17353931 | |
| GO:0009055 | electron carrier activity | IEA | - | |
| GO:0015035 | protein disulfide oxidoreductase activity | IEA | - | |
| Biological process | 去的术语 | Evidence | Neuro keywords | PubMed ID |
| GO:0045454 | cell redox homeostasis | IEA | - | |
| Cellular component | 去的术语 | Evidence | Neuro keywords | PubMed ID |
| GO:0005737 | cytoplasm | IEA | - |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| TURASHVILI BREAST DUCTAL CARCINOMA VS LOBULAR NORMAL UP | 73 | 50 | All SZGR 2.0 genes in this pathway |
| TONKS TARGETS OF RUNX1 RUNX1T1 FUSION MONOCYTE UP | 204 | 140 | All SZGR 2.0 genes in this pathway |
| KINSEY TARGETS OF EWSR1 FLII FUSION UP | 1278 | 748 | All SZGR 2.0 genes in this pathway |
| RODRIGUES THYROID CARCINOMA POORLY DIFFERENTIATED UP | 633 | 376 | All SZGR 2.0 genes in this pathway |
| RODRIGUES THYROID CARCINOMA ANAPLASTIC UP | 722 | 443 | All SZGR 2.0 genes in this pathway |
| CONCANNON APOPTOSIS BY EPOXOMICIN UP | 239 | 157 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY DOXORUBICIN UP | 1142 | 669 | All SZGR 2.0 genes in this pathway |
| MARTORIATI MDM4 TARGETS FETAL LIVER UP | 227 | 137 | All SZGR 2.0 genes in this pathway |
| WEI MYCN TARGETS WITH E BOX | 795 | 478 | All SZGR 2.0 genes in this pathway |
| AMIT EGF RESPONSE 480 HELA | 164 | 118 | All SZGR 2.0 genes in this pathway |
| WANG TARGETS OF MLL CBP FUSION DN | 45 | 31 | All SZGR 2.0 genes in this pathway |
| WANG SMARCE1 TARGETS DN | 371 | 218 | All SZGR 2.0 genes in this pathway |
| HU GENOTOXIN ACTION DIRECT VS INDIRECT 24HR | 55 | 38 | All SZGR 2.0 genes in this pathway |
| MCCLUNG CREB1 TARGETS UP | 100 | 72 | All SZGR 2.0 genes in this pathway |
| LEIN MEDULLA MARKERS | 81 | 48 | All SZGR 2.0 genes in this pathway |
| MCGOWAN RSP6 TARGETS UP | 18 | 12 | All SZGR 2.0 genes in this pathway |
| 张核心血清反应 | 212 | 128 | All SZGR 2.0 genes in this pathway |
| MILI PSEUDOPODIA HAPTOTAXIS DN | 668 | 419 | All SZGR 2.0 genes in this pathway |
| FEVR CTNNB1 TARGETS DN | 553 | 343 | All SZGR 2.0 genes in this pathway |