Gene Page:TM9SF1
Summary?
| GeneID | 10548 |
| Symbol | TM9SF1 |
| Synonyms | HMP70|MP70 |
| Description | transmembrane 9 superfamily member 1 |
| Reference | HGNC:HGNC:11864|Ensembl:ENSG00000100926|HPRD: 09987|Vega:OTTHUMG00000029322 |
| Gene type | protein-coding |
| Map location | 14q11.2 |
| Pascal p-value | 0.108 |
| Sherlock p-value | 1.106E-5 |
| Fetal beta | 0.045 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| GSMA_I | Genome scan meta-analysis | Psr: 0.047 |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
某fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| EXOSC7 | 0.89 | 0.89 |
| TMED9 | 0.89 | 0.89 |
| BAX | 0.87 | 0.90 |
| TIMM44 | 0.87 | 0.88 |
| PRPF31 | 0.86 | 0.87 |
| CD2BP2 | 0.86 | 0.86 |
| SAP30BP | 0.86 | 0.87 |
| RALY | 0.86 | 0.90 |
| PUF60 | 0.86 | 0.89 |
| PAF1 | 0.86 | 0.86 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.27 | -0.77 | -0.82 |
| MT-CO2 | -0.76 | -0.79 |
| AF347015.31 | -0.75 | -0.79 |
| AF347015.33 | -0.74 | -0.79 |
| AF347015.8 | -0.74 | -0.79 |
| MT-CYB | -0.74 | -0.79 |
| AF347015.15 | -0.71 | -0.80 |
| AF347015.2 | -0.71 | -0.79 |
| AF347015.21 | -0.69 | -0.75 |
| AF347015.26 | -0.68 | -0.78 |
Section III. Gene Ontology annotation
| Cellular component | 去的术语 | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0016020 | membrane | IEA | - | |
| GO:0016021 | integral to membrane | IEA | - | |
| GO:0016021 | integral to membrane | TAS | 9332367 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP | 1382 | 904 | All SZGR 2.0 genes in this pathway |
| SCHAEFFER PROSTATE DEVELOPMENT 6HR DN | 514 | 330 | All SZGR 2.0 genes in this pathway |
| FLECHNER BIOPSY KIDNEY TRANSPLANT OK VS DONOR UP | 555 | 346 | All SZGR 2.0 genes in this pathway |
| KAAB FAILED HEART ATRIUM DN | 141 | 99 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS LATE PROGENITOR | 544 | 307 | All SZGR 2.0 genes in this pathway |
| WELCSH BRCA1 TARGETS UP | 198 | 132 | All SZGR 2.0 genes in this pathway |
| GRADE COLON AND RECTAL CANCER DN | 101 | 65 | All SZGR 2.0 genes in this pathway |
| MILI PSEUDOPODIA CHEMOTAXIS DN | 457 | 302 | All SZGR 2.0 genes in this pathway |
| MILI PSEUDOPODIA HAPTOTAXIS DN | 668 | 419 | All SZGR 2.0 genes in this pathway |
| CHANDRAN METASTASIS DN | 306 | 191 | All SZGR 2.0 genes in this pathway |