Gene Page:IFI44
Summary?
GeneID | 10561 |
Symbol | IFI44 |
Synonyms | MTAP44|TLDC5|p44 |
Description | interferon induced protein 44 |
Reference | MIM:610468|HGNC:HGNC:16938|Ensembl:ENSG00000137965|HPRD:09998|Vega:OTTHUMG00000009723 |
Gene type | protein-coding |
Map location | 1p31.1 |
Pascal p-value | 0.016 |
Sherlock p-value | 0.936 |
eGene | Cerebellar Hemisphere Myers' cis & trans |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS | |
GSMA_IIA | Genome scan meta-analysis (All samples) | Psr: 0.02692 |
Section I. Genetics and epigenetics annotation
eQTL annotation
SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
---|---|---|---|---|---|---|---|---|
rs2046622 | chr1 | 79610142 | IFI44 | 10561 | 0.04 | cis | ||
rs17092900 | chr1 | 73003409 | IFI44 | 10561 | 3.605E-6 | trans | ||
rs1338574 | chr1 | 100083461 | IFI44 | 10561 | 0.11 | trans | ||
rs17121311 | chr1 | 100314968 | IFI44 | 10561 | 0.14 | trans | ||
rs12091025 | chr1 | 149989802 | IFI44 | 10561 | 0.18 | trans | ||
rs11205098 | chr1 | 152717431 | IFI44 | 10561 | 0 | trans | ||
rs16857588 | chr2 | 11675145 | IFI44 | 10561 | 0.03 | trans | ||
rs10495652 | chr2 | 17139288 | IFI44 | 10561 | 0.01 | trans | ||
rs6531271 | chr2 | 17139932 | IFI44 | 10561 | 0.01 | trans | ||
rs12620194 | chr2 | 17148003 | IFI44 | 10561 | 0.01 | trans | ||
rs1900263 | chr2 | 80376061 | IFI44 | 10561 | 0.01 | trans | ||
rs10496239 | chr2 | 80376968 | IFI44 | 10561 | 0.01 | trans | ||
rs11679783 | chr2 | 80377391 | IFI44 | 10561 | 0.01 | trans | ||
rs17018721 | chr2 | 80385148 | IFI44 | 10561 | 0.02 | trans | ||
rs2862022 | chr2 | 80388509 | IFI44 | 10561 | 0.01 | trans | ||
rs17043176 | chr2 | 114025371 | IFI44 | 10561 | 0 | trans | ||
rs11897086 | chr2 | 184596267 | IFI44 | 10561 | 0.17 | trans | ||
rs10187085 | chr2 | 184614775 | IFI44 | 10561 | 0.14 | trans | ||
rs9989867 | chr2 | 184628012 | IFI44 | 10561 | 0.14 | trans | ||
rs890527 | chr3 | 140774852 | IFI44 | 10561 | 0.1 | trans | ||
rs7612673 | chr3 | 154499328 | IFI44 | 10561 | 0.02 | trans | ||
rs159171 | chr5 | 21186325 | IFI44 | 10561 | 0.03 | trans | ||
rs1678893 | chr5 | 31763244 | IFI44 | 10561 | 9.982E-8 | trans | ||
snp_a-2274505 | 0 | IFI44 | 10561 | 0.01 | trans | |||
rs4705861 | chr5 | 131800763 | IFI44 | 10561 | 0.16 | trans | ||
rs10491308 | chr5 | 140678473 | IFI44 | 10561 | 0.01 | trans | ||
rs10516136 | chr5 | 176381368 | IFI44 | 10561 | 0.04 | trans | ||
rs13176869 | chr5 | 179203478 | IFI44 | 10561 | 5.139E-4 | trans | ||
rs13362722 | chr6 | 6171044 | IFI44 | 10561 | 0.01 | trans | ||
rs9396602 | chr6 | 15766500 | IFI44 | 10561 | 0.15 | trans | ||
rs17668963 | chr6 | 84811128 | IFI44 | 10561 | 0.03 | trans | ||
rs1080960 | chr6 | 84815420 | IFI44 | 10561 | 9.205E-4 | trans | ||
rs13362753 | 0 | IFI44 | 10561 | 0 | trans | |||
rs7741955 | chr6 | 84829621 | IFI44 | 10561 | 3.94E-4 | trans | ||
rs17186320 | chr6 | 84897846 | IFI44 | 10561 | 0.18 | trans | ||
rs17186572 | chr6 | 84903663 | IFI44 | 10561 | 0.11 | trans | ||
rs6454356 | chr6 | 84917509 | IFI44 | 10561 | 0.12 | trans | ||
rs12524136 | chr6 | 84935440 | IFI44 | 10561 | 0 | trans | ||
rs16883826 | chr6 | 91671158 | IFI44 | 10561 | 0.14 | trans | ||
rs1918752 | chr6 | 144909076 | IFI44 | 10561 | 0.1 | trans | ||
rs9376870 | chr6 | 145206590 | IFI44 | 10561 | 0.18 | trans | ||
rs7765650 | chr6 | 145384057 | IFI44 | 10561 | 0.2 | trans | ||
rs9397692 | chr6 | 154487314 | IFI44 | 10561 | 5.144E-5 | trans | ||
rs10485060 | chr6 | 154516100 | IFI44 | 10561 | 3.24E-4 | trans | ||
rs9384190 | chr6 | 154524473 | IFI44 | 10561 | 3.324E-4 | trans | ||
rs17292544 | chr6 | 154544809 | IFI44 | 10561 | 1.882E-5 | trans | ||
rs4591922 | chr7 | 21612318 | IFI44 | 10561 | 0.15 | trans | ||
rs17171716 | chr7 | 40505332 | IFI44 | 10561 | 2.706E-4 | trans | ||
rs17160749 | chr7 | 77689922 | IFI44 | 10561 | 0.01 | trans | ||
rs3779321 | chr7 | 77691378 | IFI44 | 10561 | 0.01 | trans | ||
rs11974883 | chr7 | 78068523 | IFI44 | 10561 | 0.03 | trans | ||
rs6943724 | chr7 | 86977647 | IFI44 | 10561 | 0.19 | trans | ||
rs10503326 | chr8 | 5533604 | IFI44 | 10561 | 0.17 | trans | ||
rs6586742 | chr8 | 18208340 | IFI44 | 10561 | 0.13 | trans | ||
rs6994367 | chr8 | 58489813 | IFI44 | 10561 | 0.09 | trans | ||
rs16922399 | chr8 | 58514611 | IFI44 | 10561 | 0.09 | trans | ||
rs6994006 | chr8 | 58584893 | IFI44 | 10561 | 0.09 | trans | ||
rs1550464 | chr8 | 73674315 | IFI44 | 10561 | 0.06 | trans | ||
rs6986838 | chr8 | 91194553 | IFI44 | 10561 | 0.16 | trans | ||
rs10283729 | chr9 | 2981636 | IFI44 | 10561 | 0.12 | trans | ||
rs201062 | chr10 | 10985931 | IFI44 | 10561 | 0.01 | trans | ||
rs17111364 | chr10 | 97901813 | IFI44 | 10561 | 0.16 | trans | ||
rs10833144 | chr11 | 19656451 | IFI44 | 10561 | 4.662的军医 | trans | ||
rs11039838 | chr11 | 48592091 | IFI44 | 10561 | 0.15 | trans | ||
rs2367635 | chr11 | 116129753 | IFI44 | 10561 | 0.16 | trans | ||
rs2508654 | chr11 | 120405519 | IFI44 | 10561 | 0.15 | trans | ||
rs11067420 | chr12 | 115559121 | IFI44 | 10561 | 0.13 | trans | ||
rs17061055 | chr13 | 40835399 | IFI44 | 10561 | 5.976E-4 | trans | ||
rs17066364 | chr13 | 45515988 | IFI44 | 10561 | 4.404E-5 | trans | ||
rs3783149 | chr13 | 45582764 | IFI44 | 10561 | 0.04 | trans | ||
rs7332969 | chr13 | 45612902 | IFI44 | 10561 | 4.404E-5 | trans | ||
rs4943038 | chr13 | 52482674 | IFI44 | 10561 | 0.18 | trans | ||
rs10484008 | chr14 | 89376562 | IFI44 | 10561 | 2.441E-4 | trans | ||
rs10150770 | chr14 | 95375311 | IFI44 | 10561 | 0.01 | trans | ||
rs16955413 | chr15 | 29677652 | IFI44 | 10561 | 4.012E-7 | trans | ||
rs4457950 | chr15 | 35445709 | IFI44 | 10561 | 0.02 | trans | ||
rs16969948 | chr15 | 78864785 | IFI44 | 10561 | 0.13 | trans | ||
rs16955238 | chr16 | 81415690 | IFI44 | 10561 | 0.05 | trans | ||
rs16955255 | chr16 | 81420130 | IFI44 | 10561 | 0 | trans | ||
rs16955259 | chr16 | 81420188 | IFI44 | 10561 | 0.05 | trans | ||
rs4303487 | chr16 | 90033254 | IFI44 | 10561 | 0.16 | trans | ||
rs8098388 | chr18 | 24080746 | IFI44 | 10561 | 0.01 | trans | ||
rs8085520 | chr18 | 40184498 | IFI44 | 10561 | 0.13 | trans | ||
rs8105452 | chr19 | 11854016 | IFI44 | 10561 | 0.06 | trans | ||
rs8104298 | chr19 | 11867512 | IFI44 | 10561 | 0 | trans | ||
rs16979927 | chr20 | 55019249 | IFI44 | 10561 | 6.438E-7 | trans | ||
rs17433434 | chr20 | 56487374 | IFI44 | 10561 | 0.11 | trans | ||
rs17000687 | chr22 | 49634054 | IFI44 | 10561 | 0.05 | trans | ||
rs17347454 | chrX | 23347700 | IFI44 | 10561 | 4.213E-8 | trans | ||
rs5952435 | chrX | 47321870 | IFI44 | 10561 | 0.07 | trans | ||
rs689365 | chrX | 97074769 | IFI44 | 10561 | 1.599E-4 | trans | ||
rs10856133 | 0 | IFI44 | 10561 | 0 | trans | |||
rs16995164 | chrX | 148536507 | IFI44 | 10561 | 0 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
![Not available](http://www.tjghsg.com/bioinfo/SZGR/GeneImg/IFI44_DE_GTEx.png)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section III. Gene Ontology annotation
Biological process | 去的术语 | Evidence | Neuro keywords | PubMed ID |
---|---|---|---|---|
GO:0009615 | response to virus | TAS | 7925411 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
TURASHVILI BREAST LOBULAR CARCINOMA VS DUCTAL NORMAL UP | 69 | 38 | All SZGR 2.0 genes in this pathway |
TURASHVILI BREAST LOBULAR CARCINOMA VS LOBULAR NORMAL DN | 74 | 42 | All SZGR 2.0 genes in this pathway |
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS DN | 463 | 290 | All SZGR 2.0 genes in this pathway |
HUTTMANN B CLL POOR SURVIVAL UP | 276 | 187 | All SZGR 2.0 genes in this pathway |
CHARAFE BREAST CANCER LUMINAL VS BASAL DN | 455 | 304 | All SZGR 2.0 genes in this pathway |
HORIUCHI WTAP TARGETS UP | 306 | 188 | All SZGR 2.0 genes in this pathway |
NOJIMA SFRP2 TARGETS DN | 25 | 18 | All SZGR 2.0 genes in this pathway |
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN | 275 | 168 | All SZGR 2.0 genes in this pathway |
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 3D UP | 182 | 110 | All SZGR 2.0 genes in this pathway |
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 8D UP | 157 | 91 | All SZGR 2.0 genes in this pathway |
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 10D UP | 194 | 122 | All SZGR 2.0 genes in this pathway |
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 16D UP | 175 | 108 | All SZGR 2.0 genes in this pathway |
MULLIGHAN MLL SIGNATURE 1 DN | 242 | 165 | All SZGR 2.0 genes in this pathway |
MULLIGHAN MLL SIGNATURE 2 DN | 281 | 186 | All SZGR 2.0 genes in this pathway |
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION MONOCYTE UP | 204 | 140 | All SZGR 2.0 genes in this pathway |
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION ERYTHROCYTE UP | 157 | 104 | All SZGR 2.0 genes in this pathway |
ZHOU INFLAMMATORY RESPONSE LPS UP | 431 | 237 | All SZGR 2.0 genes in this pathway |
KINSEY TARGETS OF EWSR1 FLII FUSION UP | 1278 | 748 | All SZGR 2.0 genes in this pathway |
DODD NASOPHARYNGEAL CARCINOMA DN | 1375 | 806 | All SZGR 2.0 genes in this pathway |
ENK UV RESPONSE KERATINOCYTE DN | 485 | 334 | All SZGR 2.0 genes in this pathway |
GRAESSMANN APOPTOSIS BY SERUM DEPRIVATION UP | 552 | 347 | All SZGR 2.0 genes in this pathway |
GRAESSMANN RESPONSE TO MC AND SERUM DEPRIVATION UP | 211 | 136 | All SZGR 2.0 genes in this pathway |
GRAESSMANN APOPTOSIS BY DOXORUBICIN UP | 1142 | 669 | All SZGR 2.0 genes in this pathway |
GAUSSMANN MLL AF4 FUSION TARGETS F UP | 185 | 119 | All SZGR 2.0 genes in this pathway |
OUELLET OVARIAN CANCER INVASIVE VS LMP UP | 117 | 85 | All SZGR 2.0 genes in this pathway |
FARMER BREAST CANCER CLUSTER 1 | 44 | 23 | All SZGR 2.0 genes in this pathway |
HERNANDEZ ABERRANT MITOSIS BY DOCETACEL 2NM UP | 81 | 57 | All SZGR 2.0 genes in this pathway |
EINAV INTERFERON SIGNATURE IN CANCER | 27 | 16 | All SZGR 2.0 genes in this pathway |
多尔STAT3 DN的目标 | 50 | 34 | All SZGR 2.0 genes in this pathway |
SEITZ NEOPLASTIC TRANSFORMATION BY 8P DELETION UP | 73 | 47 | All SZGR 2.0 genes in this pathway |
PUJANA ATM PCC NETWORK | 1442 | 892 | All SZGR 2.0 genes in this pathway |
GROSS ELK3 TARGETS DN | 32 | 17 | All SZGR 2.0 genes in this pathway |
NUYTTEN NIPP1 TARGETS UP | 769 | 437 | All SZGR 2.0 genes in this pathway |
NUYTTEN EZH2 TARGETS UP | 1037 | 673 | All SZGR 2.0 genes in this pathway |
DER IFN ALPHA RESPONSE UP | 74 | 48 | All SZGR 2.0 genes in this pathway |
TARTE PLASMA CELL VS PLASMABLAST UP | 398 | 262 | All SZGR 2.0 genes in this pathway |
BECKER TAMOXIFEN RESISTANCE UP | 50 | 36 | All SZGR 2.0 genes in this pathway |
RADAEVA RESPONSE TO IFNA1 UP | 52 | 40 | All SZGR 2.0 genes in this pathway |
DER IFN BETA RESPONSE UP | 102 | 67 | All SZGR 2.0 genes in this pathway |
GRANDVAUX IRF3 TARGETS UP | 15 | 12 | All SZGR 2.0 genes in this pathway |
LEE LIVER CANCER MYC E2F1 UP | 56 | 34 | All SZGR 2.0 genes in this pathway |
LEE LIVER CANCER E2F1 UP | 62 | 35 | All SZGR 2.0 genes in this pathway |
ROETH TERT TARGETS UP | 14 | 11 | All SZGR 2.0 genes in this pathway |
VERHAAK AML WITH NPM1 MUTATED DN | 246 | 180 | All SZGR 2.0 genes in this pathway |
LIANG SILENCED BY METHYLATION 2 | 53 | 34 | All SZGR 2.0 genes in this pathway |
TRAYNOR RETT SYNDROM UP | 45 | 33 | All SZGR 2.0 genes in this pathway |
BROWNE HCMV INFECTION 16HR UP | 225 | 139 | All SZGR 2.0 genes in this pathway |
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP | 314 | 201 | All SZGR 2.0 genes in this pathway |
CHANG IMMORTALIZED BY HPV31 DN | 65 | 45 | All SZGR 2.0 genes in this pathway |
BROWNE INTERFERON RESPONSIVE GENES | 68 | 44 | All SZGR 2.0 genes in this pathway |
IVANOVA HEMATOPOIESIS STEM CELL | 254 | 164 | All SZGR 2.0 genes in this pathway |
BROWNE HCMV INFECTION 12HR UP | 111 | 68 | All SZGR 2.0 genes in this pathway |
BAELDE DIABETIC NEPHROPATHY DN | 434 | 302 | All SZGR 2.0 genes in this pathway |
金正日LRRC3B目标 | 30 | 24 | All SZGR 2.0 genes in this pathway |
HOWLIN CITED1 TARGETS 2 UP | 17 | 10 | All SZGR 2.0 genes in this pathway |
GAVIN FOXP3 TARGETS CLUSTER P6 | 91 | 44 | All SZGR 2.0 genes in this pathway |
FOSTER TOLERANT MACROPHAGE UP | 156 | 92 | All SZGR 2.0 genes in this pathway |
HELLER SILENCED BY METHYLATION UP | 282 | 183 | All SZGR 2.0 genes in this pathway |
WALLACE PROSTATE CANCER RACE UP | 299 | 167 | All SZGR 2.0 genes in this pathway |
SARRIO EPITHELIAL MESENCHYMAL TRANSITION DN | 154 | 101 | All SZGR 2.0 genes in this pathway |
RIGGI EWING SARCOMA PROGENITOR UP | 430 | 288 | All SZGR 2.0 genes in this pathway |
ACEVEDO LIVER CANCER UP | 973 | 570 | All SZGR 2.0 genes in this pathway |
ACEVEDO METHYLATED IN LIVER CANCER DN | 940 | 425 | All SZGR 2.0 genes in this pathway |
MOSERLE IFNA RESPONSE | 31 | 19 | All SZGR 2.0 genes in this pathway |
BOQUEST STEM CELL CULTURED VS FRESH UP | 425 | 298 | All SZGR 2.0 genes in this pathway |
ZHANG INTERFERON RESPONSE | 23 | 14 | All SZGR 2.0 genes in this pathway |
WUNDER INFLAMMATORY RESPONSE AND CHOLESTEROL UP | 58 | 38 | All SZGR 2.0 genes in this pathway |
COLINA TARGETS OF 4EBP1 AND 4EBP2 | 356 | 214 | All SZGR 2.0 genes in this pathway |
JISON SICKLE CELL DISEASE UP | 181 | 106 | All SZGR 2.0 genes in this pathway |
BOYAULT LIVER CANCER SUBCLASS G5 DN | 27 | 17 | All SZGR 2.0 genes in this pathway |
WONG ADULT TISSUE STEM MODULE | 721 | 492 | All SZGR 2.0 genes in this pathway |
OHGUCHI LIVER HNF4A TARGETS UP | 44 | 30 | All SZGR 2.0 genes in this pathway |
KIM PTEN TARGETS UP | 18 | 9 | All SZGR 2.0 genes in this pathway |
KATSANOU ELAVL1 TARGETS UP | 169 | 105 | All SZGR 2.0 genes in this pathway |
PLASARI TGFB1 SIGNALING VIA NFIC 1HR DN | 106 | 77 | All SZGR 2.0 genes in this pathway |
PLASARI TGFB1 SIGNALING VIA NFIC 10HR UP | 54 | 38 | All SZGR 2.0 genes in this pathway |
KRIEG KDM3A TARGETS NOT HYPOXIA | 208 | 107 | All SZGR 2.0 genes in this pathway |
FORTSCHEGGER PHF8 TARGETS DN | 784 | 464 | All SZGR 2.0 genes in this pathway |
BOSCO INTERFERON INDUCED ANTIVIRAL MODULE | 78 | 48 | All SZGR 2.0 genes in this pathway |
ACEVEDO FGFR1 TARGETS IN PROSTATE CANCER MODEL UP | 289 | 184 | All SZGR 2.0 genes in this pathway |
ZWANG DOWN BY 2ND EGF PULSE | 293 | 119 | All SZGR 2.0 genes in this pathway |
HECKER IFNB1 TARGETS | 95 | 54 | All SZGR 2.0 genes in this pathway |