Gene Page:IFI44

Summary?
GeneID 10561
Symbol IFI44
Synonyms MTAP44|TLDC5|p44
Description interferon induced protein 44
Reference MIM:610468|HGNC:HGNC:16938|Ensembl:ENSG00000137965|HPRD:09998|Vega:OTTHUMG00000009723
Gene type protein-coding
Map location 1p31.1
Pascal p-value 0.016
Sherlock p-value 0.936
eGene Cerebellar Hemisphere
Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
GSMA_IIA Genome scan meta-analysis (All samples) Psr: 0.02692

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs2046622 chr1 79610142 IFI44 10561 0.04 cis
rs17092900 chr1 73003409 IFI44 10561 3.605E-6 trans
rs1338574 chr1 100083461 IFI44 10561 0.11 trans
rs17121311 chr1 100314968 IFI44 10561 0.14 trans
rs12091025 chr1 149989802 IFI44 10561 0.18 trans
rs11205098 chr1 152717431 IFI44 10561 0 trans
rs16857588 chr2 11675145 IFI44 10561 0.03 trans
rs10495652 chr2 17139288 IFI44 10561 0.01 trans
rs6531271 chr2 17139932 IFI44 10561 0.01 trans
rs12620194 chr2 17148003 IFI44 10561 0.01 trans
rs1900263 chr2 80376061 IFI44 10561 0.01 trans
rs10496239 chr2 80376968 IFI44 10561 0.01 trans
rs11679783 chr2 80377391 IFI44 10561 0.01 trans
rs17018721 chr2 80385148 IFI44 10561 0.02 trans
rs2862022 chr2 80388509 IFI44 10561 0.01 trans
rs17043176 chr2 114025371 IFI44 10561 0 trans
rs11897086 chr2 184596267 IFI44 10561 0.17 trans
rs10187085 chr2 184614775 IFI44 10561 0.14 trans
rs9989867 chr2 184628012 IFI44 10561 0.14 trans
rs890527 chr3 140774852 IFI44 10561 0.1 trans
rs7612673 chr3 154499328 IFI44 10561 0.02 trans
rs159171 chr5 21186325 IFI44 10561 0.03 trans
rs1678893 chr5 31763244 IFI44 10561 9.982E-8 trans
snp_a-2274505 0 IFI44 10561 0.01 trans
rs4705861 chr5 131800763 IFI44 10561 0.16 trans
rs10491308 chr5 140678473 IFI44 10561 0.01 trans
rs10516136 chr5 176381368 IFI44 10561 0.04 trans
rs13176869 chr5 179203478 IFI44 10561 5.139E-4 trans
rs13362722 chr6 6171044 IFI44 10561 0.01 trans
rs9396602 chr6 15766500 IFI44 10561 0.15 trans
rs17668963 chr6 84811128 IFI44 10561 0.03 trans
rs1080960 chr6 84815420 IFI44 10561 9.205E-4 trans
rs13362753 0 IFI44 10561 0 trans
rs7741955 chr6 84829621 IFI44 10561 3.94E-4 trans
rs17186320 chr6 84897846 IFI44 10561 0.18 trans
rs17186572 chr6 84903663 IFI44 10561 0.11 trans
rs6454356 chr6 84917509 IFI44 10561 0.12 trans
rs12524136 chr6 84935440 IFI44 10561 0 trans
rs16883826 chr6 91671158 IFI44 10561 0.14 trans
rs1918752 chr6 144909076 IFI44 10561 0.1 trans
rs9376870 chr6 145206590 IFI44 10561 0.18 trans
rs7765650 chr6 145384057 IFI44 10561 0.2 trans
rs9397692 chr6 154487314 IFI44 10561 5.144E-5 trans
rs10485060 chr6 154516100 IFI44 10561 3.24E-4 trans
rs9384190 chr6 154524473 IFI44 10561 3.324E-4 trans
rs17292544 chr6 154544809 IFI44 10561 1.882E-5 trans
rs4591922 chr7 21612318 IFI44 10561 0.15 trans
rs17171716 chr7 40505332 IFI44 10561 2.706E-4 trans
rs17160749 chr7 77689922 IFI44 10561 0.01 trans
rs3779321 chr7 77691378 IFI44 10561 0.01 trans
rs11974883 chr7 78068523 IFI44 10561 0.03 trans
rs6943724 chr7 86977647 IFI44 10561 0.19 trans
rs10503326 chr8 5533604 IFI44 10561 0.17 trans
rs6586742 chr8 18208340 IFI44 10561 0.13 trans
rs6994367 chr8 58489813 IFI44 10561 0.09 trans
rs16922399 chr8 58514611 IFI44 10561 0.09 trans
rs6994006 chr8 58584893 IFI44 10561 0.09 trans
rs1550464 chr8 73674315 IFI44 10561 0.06 trans
rs6986838 chr8 91194553 IFI44 10561 0.16 trans
rs10283729 chr9 2981636 IFI44 10561 0.12 trans
rs201062 chr10 10985931 IFI44 10561 0.01 trans
rs17111364 chr10 97901813 IFI44 10561 0.16 trans
rs10833144 chr11 19656451 IFI44 10561 4.662的军医 trans
rs11039838 chr11 48592091 IFI44 10561 0.15 trans
rs2367635 chr11 116129753 IFI44 10561 0.16 trans
rs2508654 chr11 120405519 IFI44 10561 0.15 trans
rs11067420 chr12 115559121 IFI44 10561 0.13 trans
rs17061055 chr13 40835399 IFI44 10561 5.976E-4 trans
rs17066364 chr13 45515988 IFI44 10561 4.404E-5 trans
rs3783149 chr13 45582764 IFI44 10561 0.04 trans
rs7332969 chr13 45612902 IFI44 10561 4.404E-5 trans
rs4943038 chr13 52482674 IFI44 10561 0.18 trans
rs10484008 chr14 89376562 IFI44 10561 2.441E-4 trans
rs10150770 chr14 95375311 IFI44 10561 0.01 trans
rs16955413 chr15 29677652 IFI44 10561 4.012E-7 trans
rs4457950 chr15 35445709 IFI44 10561 0.02 trans
rs16969948 chr15 78864785 IFI44 10561 0.13 trans
rs16955238 chr16 81415690 IFI44 10561 0.05 trans
rs16955255 chr16 81420130 IFI44 10561 0 trans
rs16955259 chr16 81420188 IFI44 10561 0.05 trans
rs4303487 chr16 90033254 IFI44 10561 0.16 trans
rs8098388 chr18 24080746 IFI44 10561 0.01 trans
rs8085520 chr18 40184498 IFI44 10561 0.13 trans
rs8105452 chr19 11854016 IFI44 10561 0.06 trans
rs8104298 chr19 11867512 IFI44 10561 0 trans
rs16979927 chr20 55019249 IFI44 10561 6.438E-7 trans
rs17433434 chr20 56487374 IFI44 10561 0.11 trans
rs17000687 chr22 49634054 IFI44 10561 0.05 trans
rs17347454 chrX 23347700 IFI44 10561 4.213E-8 trans
rs5952435 chrX 47321870 IFI44 10561 0.07 trans
rs689365 chrX 97074769 IFI44 10561 1.599E-4 trans
rs10856133 0 IFI44 10561 0 trans
rs16995164 chrX 148536507 IFI44 10561 0 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section III. Gene Ontology annotation

Biological process 去的术语 Evidence Neuro keywords PubMed ID
GO:0009615 response to virus TAS 7925411

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
TURASHVILI BREAST LOBULAR CARCINOMA VS DUCTAL NORMAL UP 69 38 All SZGR 2.0 genes in this pathway
TURASHVILI BREAST LOBULAR CARCINOMA VS LOBULAR NORMAL DN 74 42 All SZGR 2.0 genes in this pathway
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS DN 463 290 All SZGR 2.0 genes in this pathway
HUTTMANN B CLL POOR SURVIVAL UP 276 187 All SZGR 2.0 genes in this pathway
CHARAFE BREAST CANCER LUMINAL VS BASAL DN 455 304 All SZGR 2.0 genes in this pathway
HORIUCHI WTAP TARGETS UP 306 188 All SZGR 2.0 genes in this pathway
NOJIMA SFRP2 TARGETS DN 25 18 All SZGR 2.0 genes in this pathway
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN 275 168 All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 3D UP 182 110 All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 8D UP 157 91 All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 10D UP 194 122 All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 16D UP 175 108 All SZGR 2.0 genes in this pathway
MULLIGHAN MLL SIGNATURE 1 DN 242 165 All SZGR 2.0 genes in this pathway
MULLIGHAN MLL SIGNATURE 2 DN 281 186 All SZGR 2.0 genes in this pathway
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION MONOCYTE UP 204 140 All SZGR 2.0 genes in this pathway
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION ERYTHROCYTE UP 157 104 All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE LPS UP 431 237 All SZGR 2.0 genes in this pathway
KINSEY TARGETS OF EWSR1 FLII FUSION UP 1278 748 All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA DN 1375 806 All SZGR 2.0 genes in this pathway
ENK UV RESPONSE KERATINOCYTE DN 485 334 All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY SERUM DEPRIVATION UP 552 347 All SZGR 2.0 genes in this pathway
GRAESSMANN RESPONSE TO MC AND SERUM DEPRIVATION UP 211 136 All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN UP 1142 669 All SZGR 2.0 genes in this pathway
GAUSSMANN MLL AF4 FUSION TARGETS F UP 185 119 All SZGR 2.0 genes in this pathway
OUELLET OVARIAN CANCER INVASIVE VS LMP UP 117 85 All SZGR 2.0 genes in this pathway
FARMER BREAST CANCER CLUSTER 1 44 23 All SZGR 2.0 genes in this pathway
HERNANDEZ ABERRANT MITOSIS BY DOCETACEL 2NM UP 81 57 All SZGR 2.0 genes in this pathway
EINAV INTERFERON SIGNATURE IN CANCER 27 16 All SZGR 2.0 genes in this pathway
多尔STAT3 DN的目标 50 34 All SZGR 2.0 genes in this pathway
SEITZ NEOPLASTIC TRANSFORMATION BY 8P DELETION UP 73 47 All SZGR 2.0 genes in this pathway
PUJANA ATM PCC NETWORK 1442 892 All SZGR 2.0 genes in this pathway
GROSS ELK3 TARGETS DN 32 17 All SZGR 2.0 genes in this pathway
NUYTTEN NIPP1 TARGETS UP 769 437 All SZGR 2.0 genes in this pathway
NUYTTEN EZH2 TARGETS UP 1037 673 All SZGR 2.0 genes in this pathway
DER IFN ALPHA RESPONSE UP 74 48 All SZGR 2.0 genes in this pathway
TARTE PLASMA CELL VS PLASMABLAST UP 398 262 All SZGR 2.0 genes in this pathway
BECKER TAMOXIFEN RESISTANCE UP 50 36 All SZGR 2.0 genes in this pathway
RADAEVA RESPONSE TO IFNA1 UP 52 40 All SZGR 2.0 genes in this pathway
DER IFN BETA RESPONSE UP 102 67 All SZGR 2.0 genes in this pathway
GRANDVAUX IRF3 TARGETS UP 15 12 All SZGR 2.0 genes in this pathway
LEE LIVER CANCER MYC E2F1 UP 56 34 All SZGR 2.0 genes in this pathway
LEE LIVER CANCER E2F1 UP 62 35 All SZGR 2.0 genes in this pathway
ROETH TERT TARGETS UP 14 11 All SZGR 2.0 genes in this pathway
VERHAAK AML WITH NPM1 MUTATED DN 246 180 All SZGR 2.0 genes in this pathway
LIANG SILENCED BY METHYLATION 2 53 34 All SZGR 2.0 genes in this pathway
TRAYNOR RETT SYNDROM UP 45 33 All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 16HR UP 225 139 All SZGR 2.0 genes in this pathway
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP 314 201 All SZGR 2.0 genes in this pathway
CHANG IMMORTALIZED BY HPV31 DN 65 45 All SZGR 2.0 genes in this pathway
BROWNE INTERFERON RESPONSIVE GENES 68 44 All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS STEM CELL 254 164 All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 12HR UP 111 68 All SZGR 2.0 genes in this pathway
BAELDE DIABETIC NEPHROPATHY DN 434 302 All SZGR 2.0 genes in this pathway
金正日LRRC3B目标 30 24 All SZGR 2.0 genes in this pathway
HOWLIN CITED1 TARGETS 2 UP 17 10 All SZGR 2.0 genes in this pathway
GAVIN FOXP3 TARGETS CLUSTER P6 91 44 All SZGR 2.0 genes in this pathway
FOSTER TOLERANT MACROPHAGE UP 156 92 All SZGR 2.0 genes in this pathway
HELLER SILENCED BY METHYLATION UP 282 183 All SZGR 2.0 genes in this pathway
WALLACE PROSTATE CANCER RACE UP 299 167 All SZGR 2.0 genes in this pathway
SARRIO EPITHELIAL MESENCHYMAL TRANSITION DN 154 101 All SZGR 2.0 genes in this pathway
RIGGI EWING SARCOMA PROGENITOR UP 430 288 All SZGR 2.0 genes in this pathway
ACEVEDO LIVER CANCER UP 973 570 All SZGR 2.0 genes in this pathway
ACEVEDO METHYLATED IN LIVER CANCER DN 940 425 All SZGR 2.0 genes in this pathway
MOSERLE IFNA RESPONSE 31 19 All SZGR 2.0 genes in this pathway
BOQUEST STEM CELL CULTURED VS FRESH UP 425 298 All SZGR 2.0 genes in this pathway
ZHANG INTERFERON RESPONSE 23 14 All SZGR 2.0 genes in this pathway
WUNDER INFLAMMATORY RESPONSE AND CHOLESTEROL UP 58 38 All SZGR 2.0 genes in this pathway
COLINA TARGETS OF 4EBP1 AND 4EBP2 356 214 All SZGR 2.0 genes in this pathway
JISON SICKLE CELL DISEASE UP 181 106 All SZGR 2.0 genes in this pathway
BOYAULT LIVER CANCER SUBCLASS G5 DN 27 17 All SZGR 2.0 genes in this pathway
WONG ADULT TISSUE STEM MODULE 721 492 All SZGR 2.0 genes in this pathway
OHGUCHI LIVER HNF4A TARGETS UP 44 30 All SZGR 2.0 genes in this pathway
KIM PTEN TARGETS UP 18 9 All SZGR 2.0 genes in this pathway
KATSANOU ELAVL1 TARGETS UP 169 105 All SZGR 2.0 genes in this pathway
PLASARI TGFB1 SIGNALING VIA NFIC 1HR DN 106 77 All SZGR 2.0 genes in this pathway
PLASARI TGFB1 SIGNALING VIA NFIC 10HR UP 54 38 All SZGR 2.0 genes in this pathway
KRIEG KDM3A TARGETS NOT HYPOXIA 208 107 All SZGR 2.0 genes in this pathway
FORTSCHEGGER PHF8 TARGETS DN 784 464 All SZGR 2.0 genes in this pathway
BOSCO INTERFERON INDUCED ANTIVIRAL MODULE 78 48 All SZGR 2.0 genes in this pathway
ACEVEDO FGFR1 TARGETS IN PROSTATE CANCER MODEL UP 289 184 All SZGR 2.0 genes in this pathway
ZWANG DOWN BY 2ND EGF PULSE 293 119 All SZGR 2.0 genes in this pathway
HECKER IFNB1 TARGETS 95 54 All SZGR 2.0 genes in this pathway