Gene Page:STAMBP

Summary?
GeneID 10617
Symbol STAMBP
Synonyms AMSH|MICCAP
Description STAM binding protein
Reference MIM: 606247|HGNC:HGNC:16950|Ensembl:ENSG00000124356|HPRD:05877|Vega:OTTHUMG00000129817
Gene type protein-coding
Map location 2p13.1
Pascal p-value 0.03
Sherlock p-value 0.759

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
Network Shortest path distance of core genes in the Human protein-protein interaction network Contribution to shortest path in PPI network: 0.0096

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
MKKS 0.86 0.84
TMEM111 0.86 0.84
PRKAG1 0.86 0.80
GABARAPL2 0.86 0.84
MRPS7 0.86 0.84
TMEM85 0.85 0.79
COPS4 0.85 0.83
TSFM 0.85 0.80
SNX17 0.84 0.85
YIPF1 0.84 0.81
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
AF347015.18 -0.60 -0.36
AF347015.2 -0.52 -0.25
AF347015.26 -0.51 -0.28
AC010300.1 -0.51 -0.50
AC100783.1 -0.51 -0.39
AF347015.8 -0.49 -0.25
MT-ATP8 -0.48 -0.26
C10orf108 -0.48 -0.43
AC016705.1 -0.48 -0.34
AF347015.21 -0.47 -0.20

Section III. Gene Ontology annotation

Molecular function GO term Evidence Neuro keywords PubMed ID
GO:0005515 protein binding 新闻学会 10383417|14755250
GO:0004221 泛素thiolesterase activity IEA -
GO:0008270 zinc ion binding IEA -
GO:0008237 metallopeptidase activity IEA -
GO:0008233 peptidase activity IEA -
GO:0046872 metal ion binding IEA -
Biological process GO term Evidence Neuro keywords PubMed ID
GO:0006511 ubiquitin-dependent protein catabolic process IEA -
GO:0007259 JAK-STAT cascade TAS 10383417
GO:0008284 positive regulation of cell proliferation TAS 10383417
GO:0006916 anti-apoptosis IEA -
Cellular component GO term Evidence Neuro keywords PubMed ID
GO:0005634 nucleus TAS 10383417
GO:0005737 cytoplasm IEA -
GO:0016020 membrane IEA -

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
KEGG ENDOCYTOSIS 183 132 All SZGR 2.0 genes in this pathway
PID ERBB1 INTERNALIZATION PATHWAY 41 35 All SZGR 2.0 genes in this pathway
HOLLMANN APOPTOSIS VIA CD40 DN 267 178 All SZGR 2.0 genes in this pathway
MULLIGHAN MLL SIGNATURE 1 UP 380 236 All SZGR 2.0 genes in this pathway
MULLIGHAN MLL SIGNATURE 2 UP 418 263 All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA DN 1375 806 All SZGR 2.0 genes in this pathway
ENK UV RESPONSE EPIDERMIS UP 293 179 All SZGR 2.0 genes in this pathway
DACOSTA ERCC3 ALLELE XPCS VS TTD DN 36 27 All SZGR 2.0 genes in this pathway
MARTORIATI MDM4 TARGETS FETAL LIVER DN 514 319 All SZGR 2.0 genes in this pathway
KIM GERMINAL CENTER T HELPER UP 66 42 All SZGR 2.0 genes in this pathway
PEART HDAC PROLIFERATION CLUSTER UP 57 35 All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE DN 1237 837 All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 10HR DN 56 37 All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 14HR DN 298 200 All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS STEM CELL AND PROGENITOR 681 420 All SZGR 2.0 genes in this pathway
JIANG HYPOXIA NORMAL 311 205 All SZGR 2.0 genes in this pathway
KYNG WERNER SYNDROM AND NORMAL AGING UP 93 62 All SZGR 2.0 genes in this pathway
KIM ALL DISORDERS OLIGODENDROCYTE NUMBER CORR UP 756 494 All SZGR 2.0 genes in this pathway
HIRSCH CELLULAR TRANSFORMATION SIGNATURE UP 242 159 All SZGR 2.0 genes in this pathway
FORTSCHEGGER PHF8 TARGETS DN 784 464 All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family Target position miRNA ID miRNA seq
UTR start UTR end Match method
miR-135 424 430 m8 hsa-miR-135a UAUGGCUUUUUAUUCCUAUGUGA
hsa-miR-135b UAUGGCUUUUCAUUCCUAUGUG