Gene Page:KDELR1
Summary?
| GeneID | 10945 |
| Symbol | KDELR1 |
| Synonyms | ERD2|ERD2.1|HDEL|PM23 |
| Description | KDEL endoplasmic reticulum protein retention receptor 1 |
| Reference | MIM:131235|HGNC:HGNC:6304|Ensembl:ENSG00000105438|HPRD:00569|Vega:OTTHUMG00000183215 |
| Gene type | protein-coding |
| Map location | 19q13.3 |
| Pascal p-value | 0.319 |
| Sherlock p-value | 1.106E-6 |
| Fetal beta | 0.787 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| ZNF3 | 0.90 | 0.83 |
| SAAL1 | 0.90 | 0.85 |
| NUP107 | 0.89 | 0.85 |
| ZBED5 | 0.89 | 0.86 |
| AC106037.2 | 0.89 | 0.87 |
| ZNF20 | 0.89 | 0.83 |
| PRIM1 | 0.89 | 0.84 |
| IFT81 | 0.89 | 0.81 |
| WTAP | 0.89 | 0.82 |
| SNRPF | 0.89 | 0.87 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| HLA-F | -0.67 | -0.72 |
| FBXO2 | -0.65 | -0.70 |
| PTH1R | -0.65 | -0.72 |
| TINAGL1 | -0.64 | -0.74 |
| AF347015.27 | -0.64 | -0.73 |
| ATP10A | -0.63 | -0.74 |
| AIFM3 | -0.63 | -0.69 |
| AF347015.33 | -0.62 | -0.73 |
| MT-CO2 | -0.61 | -0.71 |
| LDHD | -0.61 | -0.66 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG霍乱弧菌感染 | 56 | 32 | All SZGR 2.0 genes in this pathway |
| BIOCARTA ARAP PATHWAY | 18 | 13 | All SZGR 2.0 genes in this pathway |
| PID ARF 3PATHWAY | 19 | 13 | All SZGR 2.0 genes in this pathway |
| GARY CD5 TARGETS UP | 473 | 314 | All SZGR 2.0 genes in this pathway |
| TIEN INTESTINE PROBIOTICS 2HR UP | 27 | 19 | All SZGR 2.0 genes in this pathway |
| TIEN INTESTINE PROBIOTICS 24HR DN | 214 | 133 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY DOXORUBICIN DN | 1781 | 1082 | All SZGR 2.0 genes in this pathway |
| LI AMPLIFIED IN LUNG CANCER | 178 | 108 | All SZGR 2.0 genes in this pathway |
| LOPEZ MBD TARGETS | 957 | 597 | All SZGR 2.0 genes in this pathway |
| PASQUALUCCI LYMPHOMA BY GC STAGE UP | 283 | 177 | All SZGR 2.0 genes in this pathway |
| TARTE PLASMA CELL VS B LYMPHOCYTE UP | 78 | 51 | All SZGR 2.0 genes in this pathway |
| BYSTRYKH HEMATOPOIESIS STEM CELL QTL TRANS | 882 | 572 | All SZGR 2.0 genes in this pathway |
| HOEGERKORP CD44 TARGETS TEMPORAL UP | 13 | 8 | All SZGR 2.0 genes in this pathway |
| JIANG VHL TARGETS | 138 | 91 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS STEM CELL AND PROGENITOR | 681 | 420 | All SZGR 2.0 genes in this pathway |
| PELLICCIOTTA HDAC IN ANTIGEN PRESENTATION DN | 49 | 38 | All SZGR 2.0 genes in this pathway |
| CHEN HOXA5 TARGETS 9HR DN | 41 | 17 | All SZGR 2.0 genes in this pathway |
| AGUIRRE PANCREATIC CANCER COPY NUMBER UP | 298 | 174 | All SZGR 2.0 genes in this pathway |
| SWEET LUNG CANCER KRAS UP | 491 | 316 | All SZGR 2.0 genes in this pathway |
| SWEET KRAS ONCOGENIC SIGNATURE | 89 | 56 | All SZGR 2.0 genes in this pathway |
| CAIRO HEPATOBLASTOMA CLASSES UP | 605 | 377 | All SZGR 2.0 genes in this pathway |
| BILANGES RAPAMYCIN SENSITIVE VIA TSC1 AND TSC2 | 73 | 37 | All SZGR 2.0 genes in this pathway |