Gene Page:HSF2BP
Summary?
| GeneID | 11077 |
| Symbol | HSF2BP |
| Synonyms | - |
| Description | heat shock transcription factor 2 binding protein |
| Reference | MIM:604554|HGNC:HGNC:5226|Ensembl:ENSG00000160207|HPRD:05186|Vega:OTTHUMG00000086863 |
| Gene type | protein-coding |
| Map location | 21q22.3 |
| Pascal p-value | 0.046 |
| eGene | 小脑 元 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
圣1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| C22orf30 | 0.92 | 0.92 |
| TGFBRAP1 | 0.90 | 0.91 |
| VPS39 | 0.90 | 0.91 |
| KIAA1409 | 0.90 | 0.90 |
| ZFYVE20 | 0.89 | 0.88 |
| KIAA0947 | 0.89 | 0.89 |
| PRDM4 | 0.89 | 0.91 |
| NR2C2 | 0.89 | 0.89 |
| MBD5 | 0.89 | 0.89 |
| DYRK1A | 0.88 | 0.89 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| MT-CO2 | -0.75 | -0.80 |
| AF347015.31 | -0.75 | -0.79 |
| AF347015.8 | -0.73 | -0.80 |
| MT-CYB | -0.73 | -0.77 |
| AF347015.27 | -0.72 | -0.77 |
| AF347015.33 | -0.71 | -0.74 |
| AF347015.15 | -0.70 | -0.77 |
| AF347015.21 | -0.70 | -0.82 |
| HIGD1B | -0.69 | -0.77 |
| AF347015.2 | -0.69 | -0.73 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| JAZAG TGFB1 SIGNALING UP | 108 | 69 | All SZGR 2.0 genes in this pathway |
| NUYTTEN EZH2 TARGETS UP | 1037 | 673 | All SZGR 2.0 genes in this pathway |
| BENPORATH MYC MAX TARGETS | 775 | 494 | All SZGR 2.0 genes in this pathway |
| SHEN SMARCA2 TARGETS DN | 357 | 212 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS EARLY PROGENITOR | 532 | 309 | All SZGR 2.0 genes in this pathway |
| SU TESTIS | 76 | 53 | All SZGR 2.0 genes in this pathway |
| SHEDDEN LUNG CANCER GOOD SURVIVAL A12 | 317 | 177 | All SZGR 2.0 genes in this pathway |
| DANG BOUND BY MYC | 1103 | 714 | All SZGR 2.0 genes in this pathway |
| BROWNE HCMV INFECTION 30MIN UP | 56 | 38 | All SZGR 2.0 genes in this pathway |
| PASINI SUZ12 TARGETS UP | 112 | 65 | All SZGR 2.0 genes in this pathway |