Gene Page:mgat4a

概括?
基因 11320
象征 mgat4a
Synonyms GNT-IV|GNT-IVA|GnT-4a
Description mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
Reference MIM:604623|HGNC:HGNC:7047|Ensembl:ENSG00000071073|HPRD：06860|Vega:OTTHUMG00000130563
Gene type protein-coding
Map location 2q12
Pascal p-value 0.161
Fetal beta -0.982

数据源中的基因
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
PMID:cooccur High-throughput literature-search 系统搜索我n PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
GSMA_I Genome scan meta-analysis Psr: 0.0004
Literature High-throughput literature-search Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias Click to show details

第一节遗传学和表观遗传学注释


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

脚注：
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

脚注：
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section III. Gene Ontology annotation

Molecular function 去的术语 Evidence Neuro keywords PubMed ID
GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity TAS 10024668
GO:0016758 transferase activity, transferring hexosyl groups IEA -
GO:0046872 metal ion binding IEA -
生物过程 去的术语 Evidence Neuro keywords PubMed ID
GO:0006491 N-glycan processing TAS 10024668
GO:0005975 carbohydrate metabolic process IEA -
Cellular component 去的术语 Evidence Neuro keywords PubMed ID
GO:0000139 Golgi membrane IEA -
GO:0005794 Golgi apparatus IEA -
GO:0005576 extracellular region IEA -
去：0016020 membrane IEA -
GO：0016021 integral to membrane IEA -

V.途径注释

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
kegg n Glycan生物合成 46 31 该途径中的所有SZGR 2.0基因
REACTOME METABOLISM OF PROTEINS 518 242 该途径中的所有SZGR 2.0基因
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION 188 116 该途径中的所有SZGR 2.0基因
REACTOME ASPARAGINE N LINKED GLYCOSYLATION 81 54 该途径中的所有SZGR 2.0基因
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION 33 24 该途径中的所有SZGR 2.0基因
REACTOME N GLYCAN ANTENNAE ELONGATION 14 10 该途径中的所有SZGR 2.0基因
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI 18 14 该途径中的所有SZGR 2.0基因
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN 136 86 该途径中的所有SZGR 2.0基因
CHARAFE BREAST CANCER LUMINAL VS BASAL UP 380 215 该途径中的所有SZGR 2.0基因
CHARAFE BREAST CANCER LUMINAL VS MESENCHYMAL UP 450 256 该途径中的所有SZGR 2.0基因
BASAKI YBX1 TARGETS DN 384 230 该途径中的所有SZGR 2.0基因
CHEBOTAEV GR TARGETS UP 77 62 该途径中的所有SZGR 2.0基因
HAMAI APOPTOSIS VIA TRAIL UP 584 356 该途径中的所有SZGR 2.0基因
PATIL LIVER CANCER 747 453 该途径中的所有SZGR 2.0基因
Vantveer乳腺癌转移DN 121 65 该途径中的所有SZGR 2.0基因
KRIGE RESPONSE TO TOSEDOSTAT 6HR DN 911 527 该途径中的所有SZGR 2.0基因
KRIGE RESPONSE TO TOSEDOSTAT 24HR DN 1011 592 该途径中的所有SZGR 2.0基因
FOSTER TOLERANT MACROPHAGE DN 409 268 该途径中的所有SZGR 2.0基因
MASSARWEH TAMOXIFEN RESISTANCE UP 578 341 该途径中的所有SZGR 2.0基因
FUJII YBX1 TARGETS DN 202 132 该途径中的所有SZGR 2.0基因
Lee区分T淋巴细胞 200 115 该途径中的所有SZGR 2.0基因
NIELSEN GIST 98 66 该途径中的所有SZGR 2.0基因
WANG RESPONSE TO GSK3 INHIBITOR SB216763 UP 397 206 该途径中的所有SZGR 2.0基因
Dutertre雌二醇反应24小时DN 505 328 该途径中的所有SZGR 2.0基因
GABRIELY MIR21 TARGETS 289 187 该途径中的所有SZGR 2.0基因
Pedrioli mir31靶向 221 120 该途径中的所有SZGR 2.0基因

Section VI. microRNA annotation

miRNA family Target position miRNA ID miRNA seq
UTR start UTR end Match method
let-7/98 89 95 m8 hsa-let-7abrain UGAGGUAGUAGGUUGUAUAGUU
hsa-let-7bbrain UGAGGUAGUAGGUUGUGUGGUU
hsa-let-7cbrain UGAGGUAGUAGGUUGUAUGGUU
hsa-let-7dbrain agagguaguagguugcauagu
hsa-let-7ebrain UGAGGUAGGAGGUUGUAUAGU
hsa-let-7fbrain UGAGGUAGUAGAUUGUAUAGUU
hsa-miR-98brain ugagguaaguuguauuguu
hsa-let-7gSZ UGAGGUAGUAGUUUGUACAGU
hsa-let-7ibrain UGAGGUAGUAGUUUGUGCUGU
miR-124/506 6257 6263 m8 hsa-miR-506 UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brain UAAGGCACGCGGUGAAUGCC
miR-125/351 395 401 1A hsa-miR-125bbrain UCCCUGAGACCCUAACUUGUGA
hsa-miR-125abrain ucccugagacccuuaaccugug
miR-139 107 114 1A,m8 hsa-miR-139brain UCUACAGUGCACGUGUCU
miR-142-3p 86 92 m8 hsa-miR-142-3p UGUAGUGUUUCCUACUUUAUGGA
miR-148/152 599 605 m8 hsa-miR-148a UCAGUGCACUACAGAACUUUGU
hsa-miR-152brain UCAGUGCAUGACAGAACUUGGG
hsa-miR-148b UCAGUGCAUCACAGAACUUUGU
mir-15/16/195/424/497 6216 6223 1A,m8 hsa-miR-15abrain UAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brain UAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrain UAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZ UAGCAGCACAGAAAUAUUGGC
hsa-miR-424 CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497 CAGCAGCACACUGUGGUUUGU
miR-194 288 294 1A hsa-miR-194 UGUAACAGCAACUCCAUGUGGA
miR-196 88 94 m8 hsa-miR-196a UAGGUAGUUUCAUGUUGUUGG
hsa-miR-196b UAGGUAGUUUCCUGUUGUUGG
miR-217 483 489 1A hsa-miR-217 UACUGCAUCAGGAACUGAUUGGAU
miR-26 79 86 1A,m8 hsa-miR-26abrain UUCAAGUAAUCCAGGAUAGGC
hsa-miR-26bSZ Uucaaguaauucaggauagguu
miR-34/449 601 608 1A,m8 HSA-MIR-34Abrain UGGCAGUGUCUUAGCUGGUUGUU
HSA-MIR-34C AGGCAGUGUAGUUAGCUGAUUGC
HSA-MIR-449 uggcaguguauuguagcuggu
HSA-MIR-449b AGGCAGUGUAUUGUUAGCUGGC
miR-369-3p 369 375 1A hsa-miR-369-3p AAUAAUACAUGGUUGAUCUUU
hsa-miR-369-3p AAUAAUACAUGGUUGAUCUUU
mir-374 257 263 m8 hsa-miR-374 UUAUAAUACAACCUGAUAAGUG
hsa-miR-374 UUAUAAUACAACCUGAUAAGUG
mir-375 667 673 1A hsa-miR-375 UUUGUUCGUUCGGCUCGCGUGA
miR-503 6217 6223 1A hsa-miR-503 UAGCAGCGGGAACAGUUCUGCAG
miR-505 6328 6334 1A hsa-miR-505 GUCAACACUUGCUGGUUUCCUC