Summary
GeneID 1363
Symbol CPE
同义词 CPH
描述 羧肽酶e
参考 MIM:114855|HGNC:HGNC:2303|ENSEMBL:ENSG00000109472|HPRD:00272|Vega:Otthumg00000150252
基因类型 蛋白质编码
地图位置 4q32.3
Pascal P值 0.052
Sherlock p-value 0.002
胎儿β -0.937
支持 CompositeSet
Darnell FMRP目标

Gene in Data Sources
基因集名称 基因组方法 描述 信息
简历:PGCNP 全基因组协会研究 GWAS
PMID:cooccur 高通量文献搜索 PubMed中的系统搜索与SCZ关键字共发生的基因。总共包括3027个基因。
Literature 高通量文献搜索 与精神分裂症关键词共同存在:精神分裂症,精神分裂症,精神分裂症,精神分裂症 点击显示详细信息
go_annotation 将与神经相关的关键字映射到基因本体论注释 Hits with neuro-related keywords: 1

Section I. Genetics and epigenetics annotation


第二节。转录组注释

一般基因表达(GTEX)

无法使用

Devlopment期间的基因表达(BrainCloud)

Footnote:
总共绘制了269个时间点,n = 38个胎儿样品(x = 1:38)。每个三角形代表一个时间点。

时间变化的基因表达(brainspan)

Footnote:
SC:亚皮质区域;SM:感觉运动区域;FC:额叶皮层;和TP:颞顶皮层
ST1:胎儿(13-26个概念后周),ST2:婴儿早期至童年(4个月至11年)和ST3:青春期至成年期(13-23年)
所示的栏表示表达分布的较低25%和上层25%。

大脑区域没有共表达基因


第三节。基因本体论注释

Molecular function 去学期 证据 神经关键字 PubMed ID
GO:0004181 金属羧肽酶活性 IEA -
去:0008270 锌离子结合 IEA -
去:0008237 金属肽酶活性 IEA -
去:0008233 肽酶活性 IEA -
GO:0046872 金属离子结合 IEA -
Biological process 去学期 证据 神经关键字 PubMed ID
GO:0007218 neuropeptide signaling pathway nas 神经递质(GO期限:8) 2334405
GO:0006464 蛋白质修饰过程 nas 2334405
去:0006508 蛋白水解 IEA -
去:0008152 代谢过程 TAS 7663508
GO:0030070 胰岛素加工 IEA -
细胞分量 去学期 证据 神经关键字 PubMed ID
去:0005576 细胞外区域 IEA -
去:0005886 质膜 TAS 9019408

Section IV. Protein-protein interaction annotation

Interactors 别名b 官方全名b 实验 Source PubMed ID
C1orf103 FLJ11269 |RIF1 |RP11-96K19.1 chromosome 1 open reading frame 103 Two-hybrid Biogrid 16169070
CHD3 Mi-2a |mi2-alpha |ZFH 染色体群酶DNA结合蛋白3 Two-hybrid Biogrid 16169070
GCG GLP1 |GLP2 |Grpp 胰高血糖素 - HPRD 11375130
GTF3C1 DKFZP686A111 |tfiiic |tfiiic220 |tfiiicalpha general transcription factor IIIC, polypeptide 1, alpha 220kDa Two-hybrid Biogrid 16169070
Med31 3110004H13rik |CGI-125 |FLJ27436 |FLJ36714 |SOH1 中介复合体亚基31 Two-hybrid Biogrid 16169070
PMCH MCH pro-melanin-concentrating hormone - HPRD 8770919
pola2 FLJ21662 |FLJ37250 聚合酶(定向DNA),α2(70KD亚基) Two-hybrid Biogrid 16169070
POLDIP2 DKFZP586F1524 |PDIP38 |pold4 聚合酶(DNA定向),Delta相互作用蛋白2 Two-hybrid Biogrid 16169070
ROBO2 KIAA1568 |SAX3 回旋处,轴突引导受体,同源2(果蝇) Two-hybrid Biogrid 16169070
RPA1 HSSB |repa1 |RF-A |RP-A |RPA70 复制蛋白A1,70KDA Two-hybrid Biogrid 16169070
UTP14A KIAA0266 |NY-CO-16 |SDCCAG16 |DJ537K23.3 UTP14,U3小核仁核糖核蛋白,同源物A(酵母) Two-hybrid Biogrid 16169070


Section V. Pathway annotation

路径名 路径大小 #szgr 2.0基因 信息
KEGG I型糖尿病 44 38 All SZGR 2.0 genes in this pathway
PID ARF6贩运途径 49 34 All SZGR 2.0 genes in this pathway
REACTOME DIABETES PATHWAYS 133 91 All SZGR 2.0 genes in this pathway
Reactome胰岛素合成和加工 21 15 All SZGR 2.0 genes in this pathway
中村肿瘤区周围与中央DN 634 384 All SZGR 2.0 genes in this pathway
王攀登目标DN 186 114 All SZGR 2.0 genes in this pathway
VECCHI GASTRIC CANCER ADVANCED VS EARLY UP 175 120 All SZGR 2.0 genes in this pathway
VECCHI GASTRIC CANCER EARLY DN 367 220 All SZGR 2.0 genes in this pathway
Senese HDAC1靶向DN 260 143 All SZGR 2.0 genes in this pathway
Wamunyokoli卵巢癌LMP DN 199 124 All SZGR 2.0 genes in this pathway
Wamunyokoli卵巢癌等级1 2 DN 67 43 All SZGR 2.0 genes in this pathway
Mayburd对L663536 DN的反应 56 32 All SZGR 2.0 genes in this pathway
甲状腺癌的Rodrigues分化不佳的DN 805 505 All SZGR 2.0 genes in this pathway
甲状腺癌变性DN 537 339 All SZGR 2.0 genes in this pathway
Gozgit ESR1靶向DN 781 465 All SZGR 2.0 genes in this pathway
chebotaev gr目标dn 120 73 All SZGR 2.0 genes in this pathway
PEREZ TP53 TARGETS 1174 695 All SZGR 2.0 genes in this pathway
kang lith pdgfra up 50 27 All SZGR 2.0 genes in this pathway
Borlak肝癌EGF UP 57 41 All SZGR 2.0 genes in this pathway
Mohankumar TLX1靶向 414 287 All SZGR 2.0 genes in this pathway
GROSS ELK3靶向 27 16 All SZGR 2.0 genes in this pathway
科林PILOCYTIC ASTROCYTOMA VS GLIOBLASTOMA UP 35 32 All SZGR 2.0 genes in this pathway
gotzmann上皮到间充质过渡dn 206 136 All SZGR 2.0 genes in this pathway
ROZANOV MMP14 TARGETS UP 266 171 All SZGR 2.0 genes in this pathway
BECKER TAMOXIFEN RESISTANCE UP 50 36 All SZGR 2.0 genes in this pathway
LEE LIVER CANCER DENA UP 60 40 All SZGR 2.0 genes in this pathway
Lee Liver Cancer E2F1 UP 62 35 All SZGR 2.0 genes in this pathway
布鲁诺造血 66 48 All SZGR 2.0 genes in this pathway
江龄大脑皮层 36 27 All SZGR 2.0 genes in this pathway
Kaab心脏中心与心室 249 170 All SZGR 2.0 genes in this pathway
江是衰老下丘脑DN 40 31 All SZGR 2.0 genes in this pathway
布朗HCMV感染48小时 180 125 All SZGR 2.0 genes in this pathway
gajate对trabectedin的反应 67 45 All SZGR 2.0 genes in this pathway
HNE和TBH的Weigel氧化应激 60 42 All SZGR 2.0 genes in this pathway
伯顿成生7 51 34 All SZGR 2.0 genes in this pathway
敏锐的回应罗格列酮DN 106 68 All SZGR 2.0 genes in this pathway
Xu GH1自分泌目标 268 157 All SZGR 2.0 genes in this pathway
Wang Smarce1靶向 280 183 All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 4 307 185 All SZGR 2.0 genes in this pathway
LEIN LOCALIZED TO DISTAL AND PROXIMAL DENDRITES 17 12 All SZGR 2.0 genes in this pathway
GAVIN FOXP3 TARGETS CLUSTER P2 79 55 All SZGR 2.0 genes in this pathway
Zheng由Foxp3绑定 491 310 All SZGR 2.0 genes in this pathway
Zheng Foxp3目标胸腺 196 137 All SZGR 2.0 genes in this pathway
ZHENG FOXP3 TARGETS IN T LYMPHOCYTE DN 37 29 All SZGR 2.0 genes in this pathway
WANG LSD1 TARGETS DN 39 30 All SZGR 2.0 genes in this pathway
Kondo EZH2目标 245 148 All SZGR 2.0 genes in this pathway
MASSARWEH三苯氧胺耐药性DN 258 160 All SZGR 2.0 genes in this pathway
阿塞维多肝癌 973 570 All SZGR 2.0 genes in this pathway
SMID BREAST CANCER NORMAL LIKE UP 476 285 All SZGR 2.0 genes in this pathway
Smid乳腺癌基础DN 701 446 All SZGR 2.0 genes in this pathway
Matzuk中央女性生育 29 25 All SZGR 2.0 genes in this pathway
Boquest干细胞培养与新鲜 425 298 All SZGR 2.0 genes in this pathway
Labbe Wnt3a靶向 112 71 All SZGR 2.0 genes in this pathway
LABBE TGFB1 TARGETS UP 102 64 All SZGR 2.0 genes in this pathway
LABBE TARGETS OF TGFB1 AND WNT3A UP 111 70 All SZGR 2.0 genes in this pathway
Boylan多发性骨髓瘤C D DN 252 155 All SZGR 2.0 genes in this pathway
WU被膀胱癌中的甲基化沉默 55 42 All SZGR 2.0 genes in this pathway
在肿瘤血管生成期间沉默的Hellebrekers 80 56 All SZGR 2.0 genes in this pathway
甜肺癌Kras DN 435 289 All SZGR 2.0 genes in this pathway
Kobayashi EGFR信号24小时 101 65 All SZGR 2.0 genes in this pathway
Boylan多发性骨髓瘤PCA1 UP 101 66 All SZGR 2.0 genes in this pathway
金双相情感障碍少突胶质细胞密度相关 682 440 All SZGR 2.0 genes in this pathway
Chicas RB1目标汇合 567 365 All SZGR 2.0 genes in this pathway
Johnstone Parvb目标2 DN 336 211 All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE VIA TP53 GROUP D 280 158 All SZGR 2.0 genes in this pathway
pasini suz12靶向DN 315 215 All SZGR 2.0 genes in this pathway
STAT3 DN的Azare肿瘤转化 17 10 All SZGR 2.0 genes in this pathway
Lee BMP2目标 745 475 All SZGR 2.0 genes in this pathway
FEVR CTNNB1靶向 682 433 All SZGR 2.0 genes in this pathway
PEDERSEN METASTASIS BY ERBB2 ISOFORM 4 110 66 All SZGR 2.0 genes in this pathway
WAKABAYASHI ADIPOGENESIS PPARG BOUND 8D 658 397 All SZGR 2.0 genes in this pathway
寄养KDM1A靶向DN 211 119 All SZGR 2.0 genes in this pathway
Zwang仅通过第一egf脉冲瞬时向上 1839年 928 All SZGR 2.0 genes in this pathway