Gene Page:SYT9

Summary?
GeneID 143425
Symbol SYT9
Synonyms -
Description synaptotagmin 9
Reference MIM:613528|HGNC:HGNC:19265|Ensembl:ENSG00000170743|HPRD:11618|Vega:OTTHUMG00000165499
Gene type protein-coding
Map location 11p15.4
Pascal p-value 0.168
TADA p-value 0.001
Fetal beta -0.946
eGene 元
Support EXOCYTOSIS

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
DNM:McCarthy_2014 Whole Exome Sequencing analysis Whole exome sequencing of 57 trios with sporadic or familial schizophrenia.
GO_Annotation Mapping neuro-related keywords to Gene Ontology annotations Hits with neuro-related keywords: 1

Section I. Genetics and epigenetics annotation

@DNM table

Gene Chromosome Position Ref Alt Transcript AA change Mutation type Sift CG46 Trait Study
SYT9 chr11 7334755 NM_175733 p.D209fs frameshift INS NA NA Schizophrenia DNM:McCarthy_2014
SYT9 chr11 7439282 C T NM_175733 . silent Schizophrenia DNM:Gulsuner_2013


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section III. Gene Ontology annotation

Molecular function 去的术语 Evidence Neuro keywords PubMed ID
GO:0005509 calcium ion binding IEA -
GO:0005515 protein binding IEA -
GO:0005215 transporter activity IEA -
Biological process 去的术语 Evidence Neuro keywords PubMed ID
GO:0006810 transport IEA -
Cellular component 去的术语 Evidence Neuro keywords PubMed ID
GO:0008021 synaptic vesicle IEA Synap, Neurotransmitter (GO term level: 12) -
GO:0045202 synapse IEA neuron, Synap, Neurotransmitter, Glial (GO term level: 2) -
GO:0016020 membrane IEA -
GO:0016021 integral to membrane IEA -
GO:0030054 cell junction IEA -
GO:0031410 cytoplasmic vesicle IEA -

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
ZHOU INFLAMMATORY RESPONSE LIVE UP 485 293 All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE FIMA UP 544 308 All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE LPS UP 431 237 All SZGR 2.0 genes in this pathway
DN CHEBOTAEV GR目标 120 73 All SZGR 2.0 genes in this pathway
YAMAZAKI TCEB3 TARGETS DN 215 132 All SZGR 2.0 genes in this pathway
YOSHIMURA MAPK8 TARGETS UP 1305 895 All SZGR 2.0 genes in this pathway
SENGUPTA EBNA1 ANTICORRELATED 173 85 All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family Target position miRNA ID miRNA seq
UTR start UTR end Match method
miR-196 465 471 m8 hsa-miR-196a UAGGUAGUUUCAUGUUGUUGG
hsa-miR-196b UAGGUAGUUUCCUGUUGUUGG
miR-29 429 435 1A hsa-miR-29aSZ UAGCACCAUCUGAAAUCGGUU
hsa-miR-29bSZ UAGCACCAUUUGAAAUCAGUGUU
hsa-miR-29cSZ UAGCACCAUUUGAAAUCGGU
miR-544 1782 1788 1A hsa-miR-544 AUUCUGCAUUUUUAGCAAGU
miR-9 1213 1219 m8 hsa-miR-9SZ UCUUUGGUUAUCUAGCUGUAUGA