基因Page:CSF1

Summary？
基因 1435
象征 CSF1
Synonyms CSF-1|MCSF
Description 菌落刺激因子1
Reference MIM：120420|HGNC：HGNC：2432|ENSEMBL：ENSG00000184371|HPRD：00388|Vega：Otthumg0000000011646
基因类型 蛋白质编码
Map location 1p13.3
Pascal p-value 0.515
胎儿β 0.336
DMG 1(# studies)
主持人 小脑
元

基因in Data Sources
基因集名称 Method of gene set Description 信息
CV:PGCnp 全基因组协会研究 GWAS
DMG：Wockner_2014 全基因组DNA甲基化分析 该数据集包括4641个差异甲基化探针，对应于精神分裂症患者（n = 24）和对照组（n = 24）之间的2929个独特基因。 1
GSMA_I Genome scan meta-analysis PSR：0.0235

Section I. Genetics and epigenetics annotation

@差异甲基化基因

Probe 染色体 位置 最近的基因 p（dis） Beta (dis) fdr（dis） 学习
CG02457085 1 110457683 CSF1 8.57e-5 -0.415 0.026 DMG：Wockner_2014


第二节。转录组注释

一般基因表达（GTEX）

无法使用

Devlopment期间的基因表达（BrainCloud）

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

时间变化的基因表达（brainspan）

Footnote:
SC：亚皮质区域；SM：感觉运动区域；FC：额叶皮层；和TP：颞顶皮层
ST1：胎儿（13-26个概念后周），ST2：婴儿早期至童年（4个月至11年）和ST3：青春期至成年期（13-23年）
所示的栏表示表达分布的较低25％和上层25％。

No co-expressed genes in brain regions


第三节。基因本体论注释

分子功能 去学期 证据 神经关键字 PubMed ID
去：0005157 巨噬细胞刺激因子受体结合 TAS 2460758
生物过程 去学期 证据 神经关键字 PubMed ID
GO:0008284 细胞增殖的阳性调节 TAS 2460758
GO:0030154 细胞分化 nas 1791839
GO：0030225 巨噬细胞分化 TAS 2460758
GO:0030097 血压 nas 1791839
Cellular component 去学期 证据 神经关键字 PubMed ID
去：0005576 细胞外区域 IEA -
去：0005615 细胞外空间 IEA -
GO：0016021 膜不可或缺 IEA -
去：0005886 plasma membrane IEA -

Section V. Pathway annotation

路径名 路径大小 # SZGR 2.0 genes in pathway 信息
KEGG细胞因子细胞因子受体相互作用 267 161 All SZGR 2.0 genes in this pathway
KEGG造血细胞谱系 88 60 All SZGR 2.0 genes in this pathway
Biocarta fordam途径 29 24 All SZGR 2.0 genes in this pathway
Biocarta ETS途径 18 12 All SZGR 2.0 genes in this pathway
生物卡塔茎途径 15 13 All SZGR 2.0 genes in this pathway
SA MMP细胞因子连接 15 9 All SZGR 2.0 genes in this pathway
PID PTP1B途径 52 40 All SZGR 2.0 genes in this pathway
PID TCPTP PATHWAY 43 33 All SZGR 2.0 genes in this pathway
PID AVB3整合素途径 75 53 All SZGR 2.0 genes in this pathway
LIU SOX4 TARGETS UP 137 94 All SZGR 2.0 genes in this pathway
GAZDA钻石黑芬贫血红细胞侵蚀 25 18 All SZGR 2.0 genes in this pathway
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS UP 579 346 All SZGR 2.0 genes in this pathway
迪亚兹慢性巨态性白血病 1382 904 All SZGR 2.0 genes in this pathway
Horiuchi WTAP靶向 306 188 All SZGR 2.0 genes in this pathway
NOJIMA SFRP2靶向 31 23 All SZGR 2.0 genes in this pathway
runx1 runx1t1融合HSC DN的TONKS目标 187 115 All SZGR 2.0 genes in this pathway
runx1 runx1t1融合单核细胞的TONKS目标 204 140 All SZGR 2.0 genes in this pathway
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION SUSTAINED IN MONOCYTE UP 21 15 All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE FIMA UP 544 308 All SZGR 2.0 genes in this pathway
Kim WT1靶向 214 155 All SZGR 2.0 genes in this pathway
Kim WT1靶向8小时 164 122 All SZGR 2.0 genes in this pathway
Kim WT1靶向12小时 162 116 All SZGR 2.0 genes in this pathway
ENK UV响应表皮增强 293 179 All SZGR 2.0 genes in this pathway
CHIARADONNA NEOPLASTIC TRANSFORMATION CDC25 UP 120 73 All SZGR 2.0 genes in this pathway
BERENJENO ROCK SIGNALING NOT VIA RHOA DN 48 34 All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY SERUM DEPRIVATION UP 552 347 All SZGR 2.0 genes in this pathway
GRAESSMANN RESPONSE TO MC AND SERUM DEPRIVATION UP 211 136 All SZGR 2.0 genes in this pathway
阿霉素的Graessmann凋亡 1142 669 All SZGR 2.0 genes in this pathway
RASHI RESPONSE TO IONIZING RADIATION 2 127 92 All SZGR 2.0 genes in this pathway
RASHI NFKB1 TARGETS 19 18 All SZGR 2.0 genes in this pathway
埃尔南德斯有丝分裂逮捕Docetaxel 2 Up 64 45 All SZGR 2.0 genes in this pathway
Hatada甲基化在肺癌中 390 236 All SZGR 2.0 genes in this pathway
GROSS HYPOXIA VIA ELK3 UP 209 139 All SZGR 2.0 genes in this pathway
通过HIF1A的总缺氧 77 49 All SZGR 2.0 genes in this pathway
Nuytten EZH2靶向 1037 673 All SZGR 2.0 genes in this pathway
GOTZMANN EPITHELIAL TO MESENCHYMAL TRANSITION UP 69 55 All SZGR 2.0 genes in this pathway
Benporath Suz12目标 1038 678 All SZGR 2.0 genes in this pathway
BENPORATH ES与H3K27ME3 1118 744 All SZGR 2.0 genes in this pathway
JEON SMAD6 TARGETS UP 24 15 All SZGR 2.0 genes in this pathway
tarte浆细胞与Plasmablast向上 398 262 All SZGR 2.0 genes in this pathway
sana tnf发出信号 83 56 All SZGR 2.0 genes in this pathway
Lenaour树突状细胞成熟 114 84 All SZGR 2.0 genes in this pathway
MUNSHI MULTIPLE MYELOMA UP 81 52 All SZGR 2.0 genes in this pathway
阿尔茨海默氏症疾病初期 390 242 All SZGR 2.0 genes in this pathway
JOSEPH RESPONSE TO SODIUM BUTYRATE DN 64 45 All SZGR 2.0 genes in this pathway
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 2 50 34 All SZGR 2.0 genes in this pathway
KAYO AGING MUSCLE UP 244 165 All SZGR 2.0 genes in this pathway
WANG CISPLATIN RESPONSE AND XPC DN 228 146 All SZGR 2.0 genes in this pathway
阿尔茨海默氏症疾病 1691 1088 All SZGR 2.0 genes in this pathway
杰克逊DNMT1靶向 77 57 All SZGR 2.0 genes in this pathway
Burton脂肪形成峰在0hr 63 48 All SZGR 2.0 genes in this pathway
safford t淋巴细胞厌食 87 54 All SZGR 2.0 genes in this pathway
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 1 419 273 All SZGR 2.0 genes in this pathway
伯顿成生成9 92 59 All SZGR 2.0 genes in this pathway
由FOXP3绑定的Marson刺激 1022 619 All SZGR 2.0 genes in this pathway
FOSTER TOLERANT MACROPHAGE DN 409 268 All SZGR 2.0 genes in this pathway
Rizki肿瘤侵入性3D 210 124 All SZGR 2.0 genes in this pathway
Bonome卵巢癌的生存次优秀 510 309 All SZGR 2.0 genes in this pathway
张乳腺癌祖细胞DN 145 93 All SZGR 2.0 genes in this pathway
MATZUK IMPLANTATION AND UTERINE 22 15 All SZGR 2.0 genes in this pathway
MATZUK植入后和产后 14 13 All SZGR 2.0 genes in this pathway
Matzuk精子 24 17 All SZGR 2.0 genes in this pathway
西肾上腺皮质肿瘤DN 546 362 All SZGR 2.0 genes in this pathway
SEKI炎症反应LPS 77 56 All SZGR 2.0 genes in this pathway
Chang Core血清反应DN 209 137 All SZGR 2.0 genes in this pathway
霍夫曼不成熟到成熟的B淋巴细胞 43 34 All SZGR 2.0 genes in this pathway
张TLX目标36hr 221 150 All SZGR 2.0 genes in this pathway
ZHANG TLX TARGETS 60HR UP 293 203 All SZGR 2.0 genes in this pathway
张TLX目标 108 78 All SZGR 2.0 genes in this pathway
MILI PSEUDOPODIA HAPTOTAXIS DN 668 419 All SZGR 2.0 genes in this pathway
BUDHU LIVER CANCER METASTASIS UP 10 7 All SZGR 2.0 genes in this pathway
Seike肺癌生存不佳 11 8 All SZGR 2.0 genes in this pathway
MARTENS TRETINOIN RESPONSE UP 857 456 All SZGR 2.0 genes in this pathway
Johnstone Parvb目标3 430 288 All SZGR 2.0 genes in this pathway
pasini suz12靶向DN 315 215 All SZGR 2.0 genes in this pathway
Gobert少突胶质细胞分化DN 1080 713 All SZGR 2.0 genes in this pathway
Servitja Islet HNF1A靶向 163 111 All SZGR 2.0 genes in this pathway
Plasari TGFB1通过NFIC 10小时信号传导 54 38 All SZGR 2.0 genes in this pathway
phong tnf响应不是通过p38 337 236 All SZGR 2.0 genes in this pathway
boudoukha由IGF2BP2绑定 111 59 All SZGR 2.0 genes in this pathway
BOSCO过敏原诱导TH2相关模块 151 86 All SZGR 2.0 genes in this pathway
SMIRNOV RESPONSE TO IR 6HR UP 166 97 All SZGR 2.0 genes in this pathway
Zwang仅通过第一egf脉冲瞬时向上 1839年 928 All SZGR 2.0 genes in this pathway
NABA分泌因素 344 197 All SZGR 2.0 genes in this pathway
NABA MATRISOME ASSOCIATED 753 411 All SZGR 2.0 genes in this pathway
NABA MATRISOME 1028 559 All SZGR 2.0 genes in this pathway

第六节。microRNA注释

mirna家族 目标位置 miRNA ID mirna seq
UTR开始 UTR结束 匹配方法
miR-128 803 810 1A，M8 hsa-miR-128a ucacagugaaccggucuuuu
hsa-miR-128b ucacagugaaccggucuuc
mir-130/301 800 806 M8 HSA-MIR-130Abrain cagugcaauguaaaaggggau
hsa-miR-301 cagugcaauaugucaaagc
HSA-MIR-130bbrain Cagugcaaugaagggauggau
hsa - mir - 454 - 3 - p uagugcaauauugcuuauaggguuu
mir-148/152 801 807 M8 HSA-MIR-148A ucagugcacuacaacuuugu
HSA-MIR-152brain UCAGUGCAUGACACUUGGG
HSA-MIR-148B ucagugcaucacacaacuuugu
mir-214 823 830 1A，M8 hsa-miR-214brain acagcaggcacagacaggcag
mir-27 804 811 1A，M8 HSA-MIR-27Abrain uucacaguggcuaaguuccgc
HSA-MIR-27Bbrain uucacaguggcuaaguucugc
mir-28 116 122 M8 hsa-miR-28brain Aaggagcucacagucuauugag
mir-96 433 439 M8 HSA-MIR-96brain uuuggcacuagcacauuuuugc