Gene Page:CSF3

Summary?
GeneID 1440
Symbol CSF3
Synonyms C17orf33|CSF3OS|GCSF
描述 colony stimulating factor 3
Reference MIM:138970|HGNC:HGNC:2438|Ensembl:ENSG00000108342|HPRD:00736|Vega:OTTHUMG00000133247
Gene type protein-coding
Map location 17q11.2-q12
Pascal p-value 0.031
eGene Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene set 描述 Info
CV:PGCnp Genome-wide Association Study GWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs10915489 chr1 4321466 CSF3 1440 2.282E-8 trans
rs1342707 chr1 147264296 CSF3 1440 0 trans
rs6426945 chr1 154776529 CSF3 1440 0.02 trans
rs7550076 chr1 154776711 CSF3 1440 0.08 trans
rs529346 chr1 160743808 CSF3 1440 0.01 trans
rs2284755 chr1 168403681 CSF3 1440 0.08 trans
rs12080632 chr1 169039280 CSF3 1440 0.05 trans
rs6658896 chr1 206926845 CSF3 1440 0.11 trans
rs17022385 chr1 207357521 CSF3 1440 0.09 trans
rs6665928 chr1 215821430 CSF3 1440 0.01 trans
rs2907143 chr1 243147434 CSF3 1440 1.16E-6 trans
rs4665576 chr2 23472338 CSF3 1440 8.5E-5 trans
rs1597005 chr2 116736707 CSF3 1440 2.275E-7 trans
rs7573503 chr2 119004157 CSF3 1440 0.02 trans
rs4078756 chr2 177004114 CSF3 1440 0.14 trans
rs885378 chr2 239962436 CSF3 1440 0.11 trans
rs4955151 chr3 32499581 CSF3 1440 0.1 trans
rs17303478 chr3 47897366 CSF3 1440 0.01 trans
rs6762371 chr3 51871404 CSF3 1440 0.17 trans
rs3772753 chr3 124145424 CSF3 1440 0.2 trans
rs4680298 chr3 156387114 CSF3 1440 0.15 trans
rs16846456 chr3 172757337 CSF3 1440 4.397E-7 trans
rs11943295 chr4 13403854 CSF3 1440 0.1 trans
rs11943330 chr4 13403997 CSF3 1440 0.04 trans
rs11933841 chr4 13463990 CSF3 1440 0.1 trans
rs7693312 chr4 13874551 CSF3 1440 0.1 trans
rs16898010 chr4 19036545 CSF3 1440 5.993E-4 trans
rs6848885 chr4 21582684 CSF3 1440 0.13 trans
rs7664889 chr4 77087703 CSF3 1440 0.12 trans
rs2053487 chr4 77097335 CSF3 1440 0.11 trans
rs13117802 chr4 77103928 CSF3 1440 0.06 trans
rs4859625 chr4 77104528 CSF3 1440 0.06 trans
rs336304 chr4 143019414 CSF3 1440 0.06 trans
rs336306 chr4 143019811 CSF3 1440 0.06 trans
rs17052594 chr4 167698562 CSF3 1440 0.02 trans
rs1588967 chr4 183191436 CSF3 1440 0.06 trans
rs4702765 chr5 10927603 CSF3 1440 0.12 trans
rs31304 chr5 52942082 CSF3 1440 0.04 trans
rs7726346 chr5 80229097 CSF3 1440 0.04 trans
rs888819 chr5 80257108 CSF3 1440 0.04 trans
rs10063177 chr5 145081194 CSF3 1440 0.13 trans
rs12110030 chr5 150448646 CSF3 1440 0.03 trans
rs6863508 chr5 159131795 CSF3 1440 0.01 trans
rs793014 chr5 172288950 CSF3 1440 0.06 trans
rs6886832 chr5 177874002 CSF3 1440 0.06 trans
rs2281127 chr6 11735767 CSF3 1440 0.01 trans
rs9466823 chr6 23572932 CSF3 1440 0.14 trans
rs7750692 chr6 69246088 CSF3 1440 0.13 trans
rs10952038 chr7 7176854 CSF3 1440 0.08 trans
rs6960358 chr7 19307526 CSF3 1440 0.01 trans
rs2191892 chr7 19327087 CSF3 1440 0.05 trans
rs2944816 chr7 71808838 CSF3 1440 0.03 trans
rs12536066 chr7 101263880 CSF3 1440 0.07 trans
rs2527853 chr7 105592670 CSF3 1440 0.15 trans
rs2072161 chr7 105662460 CSF3 1440 0.01 trans
rs849398 chr7 106524410 CSF3 1440 0.1 trans
rs7822021 chr8 8145522 CSF3 1440 2.971E-8 trans
rs7836064 chr8 8147998 CSF3 1440 0.08 trans
rs10108493 chr8 16448604 CSF3 1440 0.01 trans
rs2623858 chr8 68677367 CSF3 1440 0.13 trans
rs2623857 chr8 68677408 CSF3 1440 0.13 trans
rs6983345 chr8 90918219 CSF3 1440 0.16 trans
rs6989092 chr8 94989037 CSF3 1440 0.01 trans
rs11142899 chr9 74196408 CSF3 1440 0.16 trans
rs2082711 chr9 83109430 CSF3 1440 6.859E-6 trans
rs10993509 chr9 98071989 CSF3 1440 0.05 trans
rs7019048 chr9 102278601 CSF3 1440 0.02 trans
rs2151040 chr9 111364777 CSF3 1440 0 trans
rs11188623 chr10 97896966 CSF3 1440 0.11 trans
rs3814226 chr10 97920061 CSF3 1440 0.11 trans
rs3009929 chr10 121307427 CSF3 1440 0.09 trans
rs2912754 chr10 123261693 CSF3 1440 0.06 trans
rs16935169 chr11 18216966 CSF3 1440 0.17 trans
rs10893162 chr11 124076268 CSF3 1440 0.01 trans
rs11219545 chr11 124136438 CSF3 1440 0.01 trans
rs11219646 chr11 124279239 CSF3 1440 0.01 trans
rs2512874 chr11 131461291 CSF3 1440 1.54E-12 trans
rs985692 chr12 19309249 CSF3 1440 0.19 trans
rs1262052 chr12 55107102 CSF3 1440 0.15 trans
rs17223144 chr12 64718922 CSF3 1440 0.13 trans
rs1405500 chr12 79600640 CSF3 1440 0.09 trans
rs4143624 chr12 80947210 CSF3 1440 0.1 trans
rs3751163 chr12 121138984 CSF3 1440 0.11 trans
rs1019348 chr12 127402726 CSF3 1440 0.05 trans
rs7329574 chr13 92663432 CSF3 1440 2.234E-4 trans
rs8006993 chr14 33506969 CSF3 1440 0.09 trans
rs17101623 chr14 34085185 CSF3 1440 0 trans
rs1955728 chr14 39976063 CSF3 1440 0.11 trans
rs17103839 chr14 67491122 CSF3 1440 0.19 trans
rs17108711 chr14 71392731 CSF3 1440 0.03 trans
rs17093729 chr14 71552351 CSF3 1440 0.14 trans
rs1978163 chr14 71600636 CSF3 1440 0.02 trans
rs11846003 chr14 71602084 CSF3 1440 0.02 trans
rs17100048 chr14 101700617 CSF3 1440 0.03 trans
rs8028951 chr15 27187231 CSF3 1440 1.778E-5 trans
rs7172208 chr15 32994905 CSF3 1440 0.01 trans
rs16951575 chr15 68317450 CSF3 1440 0.07 trans
rs1559448 chr16 17530587 CSF3 1440 0.14 trans
rs8062326 chr16 19156015 CSF3 1440 0.11 trans
rs8060783 chr16 74544560 CSF3 1440 0.07 trans
rs231523 chr17 41953997 CSF3 1440 0.01 trans
rs2448755 chr18 65344801 CSF3 1440 0.18 trans
rs17196823 chr18 67270658 CSF3 1440 0.02 trans
rs16999774 chr19 23246399 CSF3 1440 0.08 trans
rs10425739 chr19 29582202 CSF3 1440 4.164E-7 trans
rs16962554 chr19 29590544 CSF3 1440 0.02 trans
rs6076051 chr20 23306825 CSF3 1440 0.19 trans
rs6076060 chr20 23345068 CSF3 1440 2.674E-7 trans
rs805944 chr20 38261717 CSF3 1440 0.13 trans
rs2148213 chr20 54798599 CSF3 1440 0 trans
rs458491 chr21 43366286 CSF3 1440 4.653E-5 trans
rs5915686 chrX 3969878 CSF3 1440 0.18 trans
rs5916432 chrX 3969940 CSF3 1440 0.18 trans
rs5916433 chrX 3970115 CSF3 1440 0.18 trans
rs16985093 chrX 8629830 CSF3 1440 0.06 trans
rs7054479 chrX 27852083 CSF3 1440 0 trans
rs16988033 chrX 27911766 CSF3 1440 0.02 trans
rs16997889 chrX 27923926 CSF3 1440 0.02 trans
rs1886581 chrX 68600054 CSF3 1440 0.04 trans
rs5977398 chrX 130127548 CSF3 1440 0.04 trans
rs12688226 chrX 141238619 CSF3 1440 0.05 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION 267 161 All SZGR 2.0 genes in this pathway
KEGG JAK STAT SIGNALING PATHWAY 155 105 All SZGR 2.0 genes in this pathway
KEGG HEMATOPOIETIC CELL LINEAGE 88 60 All SZGR 2.0 genes in this pathway
BIOCARTA GRANULOCYTES PATHWAY 14 9 All SZGR 2.0 genes in this pathway
BIOCARTA INFLAM通路 29 24 All SZGR 2.0 genes in this pathway
BIOCARTA ERYTH PATHWAY 15 11 All SZGR 2.0 genes in this pathway
BIOCARTA IL17 PATHWAY 17 12 All SZGR 2.0 genes in this pathway
BIOCARTA STEM PATHWAY 15 13 All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE LIVE UP 485 293 All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE FIMA UP 544 308 All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE LPS UP 431 237 All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN UP 1142 669 All SZGR 2.0 genes in this pathway
SEITZ NEOPLASTIC TRANSFORMATION BY 8P DELETION DN 30 25 All SZGR 2.0 genes in this pathway
PUJANA BRCA1 PCC NETWORK 1652 1023 All SZGR 2.0 genes in this pathway
PUJANA ATM PCC NETWORK 1442 892 All SZGR 2.0 genes in this pathway
GROSS HYPOXIA VIA ELK3 DN 156 106 All SZGR 2.0 genes in this pathway
GROSS HYPOXIA VIA ELK3 ONLY DN 44 30 All SZGR 2.0 genes in this pathway
NUYTTEN NIPP1 TARGETS UP 769 437 All SZGR 2.0 genes in this pathway
NIKOLSKY BREAST CANCER 17Q11 Q21 AMPLICON 133 78 All SZGR 2.0 genes in this pathway
ONDER CDH1 TARGETS 2 DN 464 276 All SZGR 2.0 genes in this pathway
ONDER CDH1 TARGETS 1 DN 169 102 All SZGR 2.0 genes in this pathway
ONDER CDH1 TARGETS 3 DN 59 32 All SZGR 2.0 genes in this pathway
NING CHRONIC OBSTRUCTIVE PULMONARY DISEASE DN 121 79 All SZGR 2.0 genes in this pathway
BYSTRYKH HEMATOPOIESIS STEM CELL QTL TRANS 882 572 All SZGR 2.0 genes in this pathway
GALINDO IMMUNE RESPONSE TO ENTEROTOXIN 85 67 All SZGR 2.0 genes in this pathway
SATO SILENCED EPIGENETICALLY IN PANCREATIC CANCER 49 30 All SZGR 2.0 genes in this pathway
LEE METASTASIS AND ALTERNATIVE SPLICING DN 45 31 All SZGR 2.0 genes in this pathway
AUJLA IL22 AND IL17A SIGNALING 11 5 All SZGR 2.0 genes in this pathway
BOQUEST STEM CELL DN 216 143 All SZGR 2.0 genes in this pathway
VART KSHV INFECTION ANGIOGENIC MARKERS DN 138 92 All SZGR 2.0 genes in this pathway
HUNSBERGER EXERCISE REGULATED GENES 31 26 All SZGR 2.0 genes in this pathway
WALLACE JAK2 TARGETS UP 26 15 All SZGR 2.0 genes in this pathway
TAVAZOIE METASTASIS 108 68 All SZGR 2.0 genes in this pathway
MIKKELSEN MCV6 LCP WITH H3K4ME3 162 80 All SZGR 2.0 genes in this pathway
HIRSCH CELLULAR TRANSFORMATION SIGNATURE UP 242 159 All SZGR 2.0 genes in this pathway
CHICAS RB1 TARGETS SENESCENT 572 352 All SZGR 2.0 genes in this pathway
WANG TNF TARGETS 24 17 All SZGR 2.0 genes in this pathway
AZARE NEOPLASTIC TRANSFORMATION BY STAT3 UP 121 70 All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY 1725 838 All SZGR 2.0 genes in this pathway
NABA SECRETED FACTORS 344 197 All SZGR 2.0 genes in this pathway
NABA MATRISOMEASSOCIATED 753 411 All SZGR 2.0 genes in this pathway
NABA MATRISOME 1028 559 All SZGR 2.0 genes in this pathway