Gene Page:ZFP90

Summary?
GeneID 146198
Symbol ZFP90
Synonyms FIK|NK10|ZNF756|zfp-90
Description ZFP90 zinc finger protein
Reference MIM:609451|HGNC:HGNC:23329|Ensembl:ENSG00000184939|HPRD:18729|Vega:OTTHUMG00000177312
Gene type protein-coding
Map location 16q22.1
Pascal p-value 0.187
Fetal beta 1.053
DMG 1 (# studies)
eGene Anterior cingulate cortex BA24
Caudate basal ganglia
Cortex
Frontal Cortex BA9
Nucleus accumbens basal ganglia

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:GWAScat Genome-wide Association Studies This data set includes 560 SNPs associated with schizophrenia. A total of 486 genes were mapped to these SNPs within 50kb.
CV:GWASdb Genome-wide Association Studies GWASdb records for schizophrenia
CV:PGCnp Genome-wide Association Study GWAS
DMG:vanEijk_2014 Genome-wide DNA methylation analysis This dataset includes 432 differentially methylated CpG sites corresponding to 391 unique transcripts between schizophrenia patients (n=260) and unaffected controls (n=250). 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

Probe Chromosome Position Nearest gene P (dis) Beta (dis) FDR (dis) Study
cg19297232 16 68483021 ZFP90 6.233E-4 -3.667 DMG:vanEijk_2014

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs820799 16 68559537 ZFP90 ENSG00000184939.11 7.327E-9 0 -4456 gtex_brain_ba24
rs698713 16 68561240 ZFP90 ENSG00000184939.11 9.637E-9 0 -2753 gtex_brain_ba24
rs71395863 16 68563358 ZFP90 ENSG00000184939.11 5.193E-6 0 -635 gtex_brain_ba24
rs1645933 16 68567169 ZFP90 ENSG00000184939.11 5.894E-6 0 3176 gtex_brain_ba24
rs1728786 16 68569706 ZFP90 ENSG00000184939.11 2.154E-9 0 5713 gtex_brain_ba24
rs1645926 16 68571225 ZFP90 ENSG00000184939.11 6.967E-6 0 7232 gtex_brain_ba24
rs1645980 16 68571619 ZFP90 ENSG00000184939.11 2.106E-9 0 7626 gtex_brain_ba24
rs1645981 16 68571648 ZFP90 ENSG00000184939.11 6.988E-6 0 7655 gtex_brain_ba24
rs1182967 16 68574378 ZFP90 ENSG00000184939.11 1.63E-8 0 10385 gtex_brain_ba24
rs2477623 16 68575176 ZFP90 ENSG00000184939.11 3.281E-6 0 11183 gtex_brain_ba24
rs821166 16 68578481 ZFP90 ENSG00000184939.11 2.189E-9 0 14488 gtex_brain_ba24
rs1094281 16 68579038 ZFP90 ENSG00000184939.11 4.19E-6 0 15045 gtex_brain_ba24
rs12921494 16 68582861 ZFP90 ENSG00000184939.11 3.479E-9 0 18868 gtex_brain_ba24
rs11642045 16 68583892 ZFP90 ENSG00000184939.11 6.797E-6 0 19899 gtex_brain_ba24
rs7195656 16 68586791 ZFP90 ENSG00000184939.11 1.678E-9 0 22798 gtex_brain_ba24
rs1645929 16 68591350 ZFP90 ENSG00000184939.11 1.667E-9 0 27357 gtex_brain_ba24
rs1645937 16 68593844 ZFP90 ENSG00000184939.11 1.433E-9 0 29851 gtex_brain_ba24
rs1728790 16 68596308 ZFP90 ENSG00000184939.11 2.132E-9 0 32315 gtex_brain_ba24
rs1728791 16 68596509 ZFP90 ENSG00000184939.11 1.665E-9 0 32516 gtex_brain_ba24
rs12929568 16 68596689 ZFP90 ENSG00000184939.11 5.369E-6 0 32696 gtex_brain_ba24
rs1177648 16 68598007 ZFP90 ENSG00000184939.11 2.105E-9 0 34014 gtex_brain_ba24
rs7499785 16 68601285 ZFP90 ENSG00000184939.11 1.664E-9 0 37292 gtex_brain_ba24
rs1728793 16 68602693 ZFP90 ENSG00000184939.11 2.344E-8 0 38700 gtex_brain_ba24
rs1177647 16 68603756 ZFP90 ENSG00000184939.11 1.181E-8 0 39763 gtex_brain_ba24
rs1170435 16 68607398 ZFP90 ENSG00000184939.11 2.235E-9 0 43405 gtex_brain_ba24
rs71975423 16 68607904 ZFP90 ENSG00000184939.11 2.633E-8 0 43911 gtex_brain_ba24
rs1094284 16 68631592 ZFP90 ENSG00000184939.11 5.846E-6 0 67599 gtex_brain_ba24
rs1094283 16 68632174 ZFP90 ENSG00000184939.11 5.881E-6 0 68181 gtex_brain_ba24
rs71148919 16 68633216 ZFP90 ENSG00000184939.11 5.945E-6 0 69223 gtex_brain_ba24
rs1170421 16 68635336 ZFP90 ENSG00000184939.11 2.842E-6 0 71343 gtex_brain_ba24
rs398029790 16 68644267 ZFP90 ENSG00000184939.11 3.395E-6 0 80274 gtex_brain_ba24
rs12919811 16 68655278 ZFP90 ENSG00000184939.11 4.585E-6 0 91285 gtex_brain_ba24

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconceptionweeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
REACTOME GENERIC TRANSCRIPTION PATHWAY 352 181 All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN DN 1781 1082 All SZGR 2.0 genes in this pathway
BERENJENO TRANSFORMED BY RHOA DN 394 258 All SZGR 2.0 genes in this pathway
PEREZ TP53 TARGETS 1174 695 All SZGR 2.0 genes in this pathway
HERNANDEZ ABERRANT MITOSIS BY DOCETACEL 2NM UP 81 57 All SZGR 2.0 genes in this pathway
GARCIA TARGETS OF FLI1 AND DAX1 UP 57 34 All SZGR 2.0 genes in this pathway
RICKMAN METASTASIS UP 344 180 All SZGR 2.0 genes in this pathway
ZHAN MULTIPLE MYELOMA CD1 AND CD2 UP 89 51 All SZGR 2.0 genes in this pathway
LEE AGING MUSCLE UP 45 33 All SZGR 2.0 genes in this pathway
MCCABE BOUND BY HOXC6 469 239 All SZGR 2.0 genes in this pathway
CHEN METABOLIC SYNDROM NETWORK 1210 725 All SZGR 2.0 genes in this pathway
WONG ADULT TISSUE STEM MODULE 721 492 All SZGR 2.0 genes in this pathway