Summary
GeneID 1500
Symbol ctnnd1
同义词 CAS | CTNND | P120CAS | P120CTN | P120 | P120(CAS)| P120(CTN)
描述 catenin delta 1
Reference MIM: 601045|HGNC:HGNC:2515|Ensembl:ENSG00000198561|HPRD:03026|织女:OTTHUMG00000167272
基因类型 蛋白质编码
地图位置 11q11
Pascal P值 2.403E-6
Sherlock p-value 0.26
支持 细胞内信号转导
G2CDB.HUMAN_BAYES-COLLINS-HUMAN-PSD-CONSESUS
G2CDB.HUMAN_BAYES-COLLINS-HUMAN-PSD-FULL
G2CDB.HUMAN_BAYES-COLLINS-MOUSE-PSD-CONSUS
CompositeSet

Gene in Data Sources
基因集名称 基因组方法 描述 信息
简历:PGCNP 全基因组协会研究 GWAS
网络 Shortest path distance of core genes in the Human protein-protein interaction network Contribution to shortest path in PPI network: 0.5323

Section I. Genetics and epigenetics annotation


第二节。转录组注释

一般基因表达(GTEX)

无法使用

时间变化的基因表达(brainspan)

Footnote:
SC:亚皮质区域;SM:感觉运动区域;FC:额叶皮层;和TP:颞顶皮层
ST1:胎儿(13-26个概念后周),ST2:婴儿早期至童年(4个月至11年)和ST3:青春期至成年期(13-23年)
所示的栏表示表达分布的较低25%和上层25%。

No co-expressed genes in brain regions


第三节。基因本体论注释

Molecular function 去学期 证据 神经关键字 PubMed ID
去:0005488 捆绑 IEA -
去:0005515 protein binding IEA -
去:0005198 结构分子活性 IEA -
Biological process 去学期 证据 神经关键字 PubMed ID
GO:0006355 调节转录,DNA依赖性的调节 IEA -
GO:0006350 转录 IEA -
GO:0016055 Wnt受体信号通路 IEA -
GO:0016337 细胞细胞粘附 nas -
细胞分量 去学期 证据 神经关键字 PubMed ID
去:0005624 膜分数 IEA -
去:0005634 nucleus nas -
去:0005737 cytoplasm nas -
GO:0030027 薄片 IEA -
去:0005886 质膜 IEA -

Section IV. Protein-protein interaction annotation

Interactors 别名b 官方全名b 实验 Source PubMed ID
ACTG1 行为|ACTG |DFNA20 |DFNA26 actin, gamma 1 亲和力捕获 - 韦斯特恩 Biogrid 12835311
CDH1 弧1 |CD324 |cdhe |ECAD |lcam |UVO 钙粘蛋白1,1型,e-钙粘蛋白(上皮) CDH1(ECAD)与P120CTN 3AC相互作用。这种相互作用是在小鼠CDH1(ECAD)和人P120CTN 3AC之间的相互作用上建模的。 绑定 12707304
CDH1 弧1 |CD324 |cdhe |ECAD |lcam |UVO 钙粘蛋白1,1型,e-钙粘蛋白(上皮) - HPRD 7651399|10409703 | 10225956
|10931041
CDH1 弧1 |CD324 |cdhe |ECAD |lcam |UVO 钙粘蛋白1,1型,e-钙粘蛋白(上皮) 亲和力捕获 - 韦斯特恩
重构的复合物
Two-hybrid
Biogrid 7542250|7651399
|7876318|9535896
|10409703|12427869
|12640114|12707304
CDH2 CD325 | CDHN | CDw325 | NCAD 钙粘蛋白2,1型,N-钙粘蛋白(神经元) Affinity Capture-MS
亲和力捕获 - 韦斯特恩
Biogrid 12604612|14625392
CDH24 CDH11L | FLJ25193 | MGC131880 钙粘蛋白样24 - HPRD 12734196
CDH3 CDHP |HJMD |PCAD cadherin 3, type 1, P-cadherin (placental) - HPRD,Biogrid 8660921
CDH5 7B4 |CD144 |FLJ17376 钙粘蛋白5,2型(血管内皮) - HPRD,Biogrid 11855855
Col17a1 BA16H23.2 |BP180 |BPAG2 |FLJ60881 |KIAA0204 |lad-1 胶原蛋白,第XVII型,Alpha 1 - HPRD,Biogrid 10321838
CTNNA1 CAP102 |FLJ36832 Catenin(cadherin相关蛋白),α1,102KDA 亲和力捕获 - 韦斯特恩 Biogrid 7651399
CTNNB1 CTNNB | DKFZp686D02253 | FLJ25606 | FLJ37923 Catenin(cadherin相关蛋白),β1,88KDA 亲和力捕获 - 韦斯特恩 Biogrid 9535896|11712088
cttn EMS1 | FLJ34459 cortactin - HPRD,Biogrid 12835311
egfr ERBB |ERBB1 |her1 |PIG61 |梅纳 表皮生长因子受体(红细胞性白血病病毒(V-ERB-B)癌基因同源物,鸟类) 重构的复合物 Biogrid 9535896
ERBB2IP Erbin |LAP2 erbb2 interacting protein - HPRD,Biogrid 11821434
FER tyk3 FER(FPS/FES相关)酪氨酸激酶 - HPRD 12640114
FYN MGC45350 | SLK | SYN Fyn Oncogene与SRC,FGR,是的 亲和力捕获 - 韦斯特恩
生化活动
Biogrid 12640114|12835311
Grik2 EAA4 |Glr6 |Gluk6 |glur6 |MGC74427 |MRT6 谷氨酸受体,离子型,海藻酸盐2 - HPRD 12151522
LCK yt16 |p56lck |pp58lck 淋巴细胞特异性蛋白酪氨酸激酶 生化活动 Biogrid 12835311
MUC1 CD227 |EMA |H23AG |mam6 |Pem |Pemt |棕榈 粘蛋白1,细胞表面相关 - HPRD,Biogrid 11181067
NPHS1 CNF |nphn 肾脏病1,先天性,芬兰类型(肾素) 亲和力捕获 - 韦斯特恩
重构的复合物
Biogrid 15331416
PSEN1 ad3 |时尚|PS1 |S182 Presenilin 1 亲和力捕获 - 韦斯特恩
重构的复合物
Two-hybrid
Biogrid 10208590
PTPN6 HCP | HCPH | HPTP1C | PTP-1C | SH-PTP1 | SHP-1 | SHP-1L | SHP1 protein tyrosine phosphatase, non-receptor type 6 - HPRD,Biogrid 10835420
ptprj CD148 |dep1 |hptpeta |R-PTP-ETA |SCC1 蛋白酪氨酸磷酸酶,受体类型,J - HPRD,Biogrid 12370829
ptprm MGC166994 |ptprl1 |R-PTP-MU |rptpm |rptpu |HR-PTPU 蛋白酪氨酸磷酸酶,受体类型,M - HPRD,Biogrid 10753936
SRC ASV | SRC1 | c-SRC | p60-Src v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 亲和力捕获 - 韦斯特恩 Biogrid 12640114
是的1 HST441 |p61-yes |是|c-yes v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 亲和力捕获 - 韦斯特恩 Biogrid 12640114
ZBTB33 Znf-Kaiso |ZNF348 zinc finger and BTB domain containing 33 - HPRD,Biogrid 10207085


Section V. Pathway annotation

路径名 路径大小 #szgr 2.0基因 信息
KEGG ADHERENS JUNCTION 75 53 All SZGR 2.0 genes in this pathway
KEGG LEUKOCYTE TRANSENDOTHELIAL MIGRATION 118 78 All SZGR 2.0 genes in this pathway
PID ARF6贩运途径 49 34 All SZGR 2.0 genes in this pathway
pid ajdiss 2Pathway 48 38 All SZGR 2.0 genes in this pathway
PID Ecadherin新生AJ途径 39 33 All SZGR 2.0 genes in this pathway
PID Ecadherin角质形成细胞途径 21 19 All SZGR 2.0 genes in this pathway
PID Ecadherin稳定途径 42 34 All SZGR 2.0 genes in this pathway
PID NCADHERIN PATHWAY 33 32 All SZGR 2.0 genes in this pathway
PID FGF途径 55 37 All SZGR 2.0 genes in this pathway
Reactome细胞通信 120 77 All SZGR 2.0 genes in this pathway
Reactome Adherens连接相互作用 27 20 All SZGR 2.0 genes in this pathway
REACTOME CELL CELL JUNCTION ORGANIZATION 56 31 All SZGR 2.0 genes in this pathway
Reactome细胞连接组织 78 43 All SZGR 2.0 genes in this pathway
家长mtor信号向上 567 375 All SZGR 2.0 genes in this pathway
迪亚兹慢性巨态性白血病 1382 904 All SZGR 2.0 genes in this pathway
Wang LMO4靶向DN 352 225 All SZGR 2.0 genes in this pathway
Jaeger转移DN 258 141 All SZGR 2.0 genes in this pathway
Ginestier乳腺癌Znf217扩增DN 335 193 All SZGR 2.0 genes in this pathway
UDayakumar Med1靶向 135 82 All SZGR 2.0 genes in this pathway
甲状腺癌的Rodrigues分化不佳的DN 805 505 All SZGR 2.0 genes in this pathway
Landis Erbb2乳腺肿瘤324向上 150 93 All SZGR 2.0 genes in this pathway
Berenjeno由Rhoa DN转变 394 258 All SZGR 2.0 genes in this pathway
pDGFB DN的Johansson神经胶质作用 21 16 All SZGR 2.0 genes in this pathway
IVANOV MUTATED IN COLON CANCER 13 9 All SZGR 2.0 genes in this pathway
TONG INTERACT WITH PTTG1 57 32 All SZGR 2.0 genes in this pathway
Benporath循环基因 648 385 All SZGR 2.0 genes in this pathway
JECHLINGER EPITHELIAL TO MESENCHYMAL TRANSITION DN 66 47 All SZGR 2.0 genes in this pathway
BYSTRYKH HEMATOPOIESIS STEM CELL QTL TRANS 882 572 All SZGR 2.0 genes in this pathway
NPM1本地化的Alcalay AML 140 83 All SZGR 2.0 genes in this pathway
Wang由Hoxa9和Meis1 Up永生 31 24 All SZGR 2.0 genes in this pathway
Chiaretti急性淋巴细胞白血病ZAP70 67 33 All SZGR 2.0 genes in this pathway
MARIADASON REGULATED BY HISTONE ACETYLATION UP 83 49 All SZGR 2.0 genes in this pathway
BURTON ADIPOGENESIS 9 92 59 All SZGR 2.0 genes in this pathway
Durchdewald皮肤致癌DN 264 168 All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 5 482 296 All SZGR 2.0 genes in this pathway
kyng环境应力响应不是WS中的4NQO 40 26 All SZGR 2.0 genes in this pathway
KYNG ENVIRONMENTAL STRESS RESPONSE NOT BY GAMMA IN OLD 31 19 All SZGR 2.0 genes in this pathway
Kyng环境压力反应不是WS中伽马的 33 22 All SZGR 2.0 genes in this pathway
Kyng DNA损坏 226 164 All SZGR 2.0 genes in this pathway
Kyng环境应力反应DN 21 12 All SZGR 2.0 genes in this pathway
Massarweh tamoxifen抗性 578 341 All SZGR 2.0 genes in this pathway
王肿瘤的侵入性DN 210 128 All SZGR 2.0 genes in this pathway
Lindstedt树突状细胞成熟D 68 44 All SZGR 2.0 genes in this pathway
COULOUARN TEMPORAL TGFB1 SIGNATURE DN 138 99 All SZGR 2.0 genes in this pathway
HOSHIDA LIVER CANCER LATE RECURRENCE DN 69 48 All SZGR 2.0 genes in this pathway
Mikkelsen ES ICP与H3K4Me3 718 401 All SZGR 2.0 genes in this pathway
Mikkelsen NPC ICP带有H3K4Me3 445 257 All SZGR 2.0 genes in this pathway
Sasson对促性腺营养蛋白DN的反应 87 66 All SZGR 2.0 genes in this pathway
SASSON RESPONSE TO FORSKOLIN DN 88 68 All SZGR 2.0 genes in this pathway
惠特菲尔德细胞周期g2 m 216 124 All SZGR 2.0 genes in this pathway
WANG RESPONSE TO GSK3 INHIBITOR SB216763 UP 397 206 All SZGR 2.0 genes in this pathway
HIF1A和FOXA2的Qi缺氧靶标 37 27 All SZGR 2.0 genes in this pathway
Johnstone Parvb目标3 430 288 All SZGR 2.0 genes in this pathway
Alfano MYC目标 239 156 All SZGR 2.0 genes in this pathway
Fortschegger PHF8靶向DN 784 464 All SZGR 2.0 genes in this pathway