Gene Page:PLB1

Summary?
GeneID 151056
Symbol PLB1
Synonyms PLB|PLB/LIP|hPLB
Description phospholipase B1
Reference MIM:610179|HGNC:HGNC:30041|Ensembl:ENSG00000163803|HPRD:15141|Vega:OTTHUMG00000152014
Gene type protein-coding
Map location 2p23.2
Pascal p-value 0.352
Fetal beta -0.765
DMG 1 (# studies)
eGene Frontal Cortex BA9

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
DMG:Wockner_2014 Genome-wide DNA methylation analysis This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

Probe Chromosome Position Nearest gene P (dis) Beta (dis) FDR (dis) Study
cg10513330 2 28829939 PLB1 6.84E-6 0.643 0.012 DMG:Wockner_2014


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26conception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
GAUSSMANN MLL AF4 FUSION TARGETS E UP 97 60 All SZGR 2.0 genes in this pathway
LASTOWSKA COAMPLIFIED WITH MYCN 43 29 All SZGR 2.0 genes in this pathway
CHEN METABOLIC SYNDROM NETWORK 1210 725 All SZGR 2.0 genes in this pathway
LIM MAMMARY LUMINAL PROGENITOR UP 58 30 All SZGR 2.0 genes in this pathway