Gene Page:PPP4R2

Summary?
GeneID 151987
Symbol PPP4R2
Synonyms PP4R2
Description protein phosphatase 4 regulatory subunit 2
Reference MIM:613822|HGNC:HGNC:18296|HPRD:11453|
Gene type protein-coding
Map location 3p13
Pascal p-value 0.021
Sherlock p-value 0.15
eGene Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
GSMA_IIE Genome scan meta-analysis (European-ancestry samples) Psr: 0.04359
GSMA_IIA Genome scan meta-analysis (All samples) Psr: 0.04047
Expression Meta-analysis of gene expression Pvalue: 2.141

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs2712089 chr2 24080273 PPP4R2 151987 0.18 trans
rs17029291 chr3 32402138 PPP4R2 151987 0.01 trans
rs1553189 chr3 112939422 PPP4R2 151987 0.2 trans
rs4615570 chr8 13349013 PPP4R2 151987 0.15 trans
rs16930362 chr10 74890320 PPP4R2 151987 0.16 trans
rs1324669 chr13 107872446 PPP4R2 151987 6.311E-7 trans
rs3742829 chr14 73489267 PPP4R2 151987 0.14 trans
rs4887786 chr16 74857551 PPP4R2 151987 0.09 trans
rs16958358 chr17 55502410 PPP4R2 151987 0.02 trans
rs2469009 chr18 70713334 PPP4R2 151987 0.14 trans
rs17638474 chr19 36061851 PPP4R2 151987 0.2 trans
rs17145698 chrX 40218345 PPP4R2 151987 3.92E-4 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
某羊乳酪l (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section III. Gene Ontology annotation

Molecular function 去的术语 Evidence Neuro keywords PubMed ID
GO:0005515 protein binding 新闻学会 17353931
Biological process 去的术语 Evidence Neuro keywords PubMed ID
GO:0006397 mRNA processing IEA -
GO:0008380 RNA splicing IEA -
GO:0006464 蛋白质改性过程 TAS 10769191
Cellular component 去的术语 Evidence Neuro keywords PubMed ID
GO:0005813 centrosome TAS 10769191

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
PARENT MTOR SIGNALING UP 567 375 All SZGR 2.0 genes in this pathway
WANG CLIM2 TARGETS DN 186 114 All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE FIMA UP 544 308 All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE LPS UP 431 237 All SZGR 2.0 genes in this pathway
RODRIGUES THYROID CARCINOMA ANAPLASTIC UP 722 443 All SZGR 2.0 genes in this pathway
HAMAI APOPTOSIS VIA TRAIL UP 584 356 All SZGR 2.0 genes in this pathway
AMUNDSON GENOTOXIC SIGNATURE 105 68 All SZGR 2.0 genes in this pathway
WEI MIR34A TARGETS 148 97 All SZGR 2.0 genes in this pathway
DING LUNG CANCER EXPRESSION BY COPY NUMBER 100 62 All SZGR 2.0 genes in this pathway
MILI PSEUDOPODIA HAPTOTAXIS UP 518 299 All SZGR 2.0 genes in this pathway
DUTERTRE ESTRADIOL RESPONSE 24HR DN 505 328 All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN 1972 1213 All SZGR 2.0 genes in this pathway
JOHNSTONE PARVB TARGETS 3 DN 918 550 All SZGR 2.0 genes in this pathway
BAKKER FOXO3 TARGETS DN 187 109 All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family Target position miRNA ID miRNA seq
UTR start UTR end Match method
miR-200bc/429 22 28 m8 hsa-miR-200b UAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200c UAAUACUGCCGGGUAAUGAUGG
hsa-miR-429 UAAUACUGUCUGGUAAAACCGU