基因页：ATP6V0E2
Summary？
| 基因 | 155066 |
| 象征 | ATP6V0E2 |
| 同义词 | ATP6V0E2L | C7orf32 |
| Description | ATPase H+运输V0亚基E2 |
| Reference | MIM：611019|HGNC:HGNC:21723|Ensembl：ENSG00000171130|HPRD：12920|Vega：Otthumg00000158094 |
| 基因类型 | 蛋白质编码 |
| 地图位置 | 7q36.1 |
| Pascal P值 | 0.191 |
| Sherlock p-value | 0.538 |
| 胎儿β | -1.116 |
| DMG | 1(# studies) |
| 主持人 | 尾状基底神经节 小脑半球 小脑 皮质 Frontal Cortex BA9 Hypothalamus 伏隔核基底神经节 Putamen basal ganglia 元 |
Gene in Data Sources
| 基因集名称 | 基因组方法 | Description | 信息 |
|---|---|---|---|
| 简历：PGCNP | 全基因组协会研究 | GWAS | |
| DMG：JAFFE_2016 | 全基因组DNA甲基化分析 | 该数据集包括与SZ患者相关的2,104个探针/CPG（n = 108），而在Bonferroni调整后的P <0.05时，其中136个对照。 | 1 |
Section I. Genetics and epigenetics annotation
差异甲基化基因
差异甲基化基因| 探测 | 染色体 | 位置 | 最近的基因 | p（dis） | β(dis) | fdr（dis） | 学习 |
|---|---|---|---|---|---|---|---|
| CG07531228 | 7 | 149745299 | ATP6V0E2 | 1.77E-9 | -0.012 | 1.53E-6 | DMG：JAFFE_2016 |
EQTL注释
| SNP ID | 染色体 | 位置 | 主持人 | Gene Entrez ID | PVALUE | QVALUE | TSS距离 | EQTL类型 |
|---|---|---|---|---|---|---|---|---|
| RS4725833 | 7 | 149556518 | ATP6V0E2 | ENSG00000171130.13 | 1.015E-8 | 0 | -13539 | gtex_brain_putamen_basal |
| rs2240361 | 7 | 149558409 | ATP6V0E2 | ENSG00000171130.13 | 8.186e-7 | 0 | -11648 | gtex_brain_putamen_basal |
| RS2074700 | 7 | 149559273 | ATP6V0E2 | ENSG00000171130.13 | 4.066e-7 | 0 | -10784 | gtex_brain_putamen_basal |
| RS2074701 | 7 | 149559465 | ATP6V0E2 | ENSG00000171130.13 | 1.578E-6 | 0 | -10592 | gtex_brain_putamen_basal |
| RS2074702 | 7 | 149559839 | ATP6V0E2 | ENSG00000171130.13 | 4.19E-7 | 0 | -10218 | gtex_brain_putamen_basal |
| RS6464035 | 7 | 149560072 | ATP6V0E2 | ENSG00000171130.13 | 1.545e-7 | 0 | -9985 | gtex_brain_putamen_basal |
| RS10270385 | 7 | 149560348 | ATP6V0E2 | ENSG00000171130.13 | 1.578E-6 | 0 | -9709 | gtex_brain_putamen_basal |
| rs2240363 | 7 | 149560785 | ATP6V0E2 | ENSG00000171130.13 | 2.374E-7 | 0 | -9272 | gtex_brain_putamen_basal |
| RS2074703 | 7 | 149560847 | ATP6V0E2 | ENSG00000171130.13 | 6.789E-9 | 0 | -9210 | gtex_brain_putamen_basal |
| rs3857764 | 7 | 149561049 | ATP6V0E2 | ENSG00000171130.13 | 5.448e-9 | 0 | -9008 | gtex_brain_putamen_basal |
| rs1859529 | 7 | 149562285 | ATP6V0E2 | ENSG00000171130.13 | 6.552E-7 | 0 | -7772 | gtex_brain_putamen_basal |
| RS3214231 | 7 | 149562627 | ATP6V0E2 | ENSG00000171130.13 | 4.154e-9 | 0 | -7430 | gtex_brain_putamen_basal |
| RS2373465 | 7 | 149563134 | ATP6V0E2 | ENSG00000171130.13 | 1.968E-8 | 0 | -6923 | gtex_brain_putamen_basal |
| RS3735330 | 7 | 149563738 | ATP6V0E2 | ENSG00000171130.13 | 3.488 e - | 0 | -6319 | gtex_brain_putamen_basal |
| RS3735331 | 7 | 149564770 | ATP6V0E2 | ENSG00000171130.13 | 2.903 e - | 0 | -5287 | gtex_brain_putamen_basal |
| RS3735332 | 7 | 149564773 | ATP6V0E2 | ENSG00000171130.13 | 2.903 e - | 0 | -5284 | gtex_brain_putamen_basal |
| RS3735333 | 7 | 149565163 | ATP6V0E2 | ENSG00000171130.13 | 5.57E-10 | 0 | -4894 | gtex_brain_putamen_basal |
| RS3735334 | 7 | 149565489 | ATP6V0E2 | ENSG00000171130.13 | 2.787E-8 | 0 | -4568 | gtex_brain_putamen_basal |
| RS9640266 | 7 | 149566175 | ATP6V0E2 | ENSG00000171130.13 | 1.168E-8 | 0 | -3882 | gtex_brain_putamen_basal |
| RS17756342 | 7 | 149567098 | ATP6V0E2 | ENSG00000171130.13 | 1.213E-7 | 0 | -2959 | gtex_brain_putamen_basal |
| rs13243007 | 7 | 149567233 | ATP6V0E2 | ENSG00000171130.13 | 2.903 e - | 0 | -2824 | gtex_brain_putamen_basal |
| rs6980166 | 7 | 149567756 | ATP6V0E2 | ENSG00000171130.13 | 1.213E-7 | 0 | -2301年 | gtex_brain_putamen_basal |
| RS4725834 | 7 | 149568262 | ATP6V0E2 | ENSG00000171130.13 | 1.213E-7 | 0 | -1795 | gtex_brain_putamen_basal |
| RS4725835 | 7 | 149568291 | ATP6V0E2 | ENSG00000171130.13 | 5.567E-10 | 0 | -1766 | gtex_brain_putamen_basal |
| RS4725836 | 7 | 149568360 | ATP6V0E2 | ENSG00000171130.13 | 1.168E-8 | 0 | -1697 | gtex_brain_putamen_basal |
| RS10952234 | 7 | 149568903 | ATP6V0E2 | ENSG00000171130.13 | 1.213E-7 | 0 | -1154 | gtex_brain_putamen_basal |
| RS917113 | 7 | 149569205 | ATP6V0E2 | ENSG00000171130.13 | 4.76E-8 | 0 | -852 | gtex_brain_putamen_basal |
| RS4401760 | 7 | 149570693 | ATP6V0E2 | ENSG00000171130.13 | 4.086e-10 | 0 | 636 | gtex_brain_putamen_basal |
| RS10240203 | 7 | 149572842 | ATP6V0E2 | ENSG00000171130.13 | 9.535e-8 | 0 | 2785 | gtex_brain_putamen_basal |
| RS4281039 | 7 | 149573293 | ATP6V0E2 | ENSG00000171130.13 | 1.772E-8 | 0 | 3236 | gtex_brain_putamen_basal |
| rs4469371 | 7 | 149573299 | ATP6V0E2 | ENSG00000171130.13 | 3.438e-7 | 0 | 3242 | gtex_brain_putamen_basal |
| RS4281040 | 7 | 149573340 | ATP6V0E2 | ENSG00000171130.13 | 1.783E-8 | 0 | 3283 | gtex_brain_putamen_basal |
| RS4281041 | 7 | 149573456 | ATP6V0E2 | ENSG00000171130.13 | 1.819E-8 | 0 | 3399 | gtex_brain_putamen_basal |
| RS4419731 | 7 | 149573553 | ATP6V0E2 | ENSG00000171130.13 | 4.348E-8 | 0 | 3496 | gtex_brain_putamen_basal |
| RS7806830 | 7 | 149573977 | ATP6V0E2 | ENSG00000171130.13 | 2.153E-9 | 0 | 3920 | gtex_brain_putamen_basal |
| RS7806974 | 7 | 149574053 | ATP6V0E2 | ENSG00000171130.13 | 2.204E-9 | 0 | 3996 | gtex_brain_putamen_basal |
| RS71531655 | 7 | 149574170 | ATP6V0E2 | ENSG00000171130.13 | 2.313E-9 | 0 | 4113 | gtex_brain_putamen_basal |
| RS10241201 | 7 | 149574268 | ATP6V0E2 | ENSG00000171130.13 | 2.371E-9 | 0 | 4211 | gtex_brain_putamen_basal |
| rs6980260 | 7 | 149575065 | ATP6V0E2 | ENSG00000171130.13 | 2.415e-10 | 0 | 5008 | gtex_brain_putamen_basal |
| rs6980277 | 7 | 149575095 | ATP6V0E2 | ENSG00000171130.13 | 1.024E-8 | 0 | 5038 | gtex_brain_putamen_basal |
| RS6967083 | 7 | 149575638 | ATP6V0E2 | ENSG00000171130.13 | 7.924e-10 | 0 | 5581 | gtex_brain_putamen_basal |
| RS6946997 | 7 | 149575707 | ATP6V0E2 | ENSG00000171130.13 | 1.117E-9 | 0 | 5650 | gtex_brain_putamen_basal |
| rs6947011 | 7 | 149575725 | ATP6V0E2 | ENSG00000171130.13 | 1.028e-8 | 0 | 5668 | gtex_brain_putamen_basal |
| RS5888369 | 7 | 149575747 | ATP6V0E2 | ENSG00000171130.13 | 8.409E-10 | 0 | 5690 | gtex_brain_putamen_basal |
| rs10246226 | 7 | 149575884 | ATP6V0E2 | ENSG00000171130.13 | 7.938e-10 | 0 | 5827 | gtex_brain_putamen_basal |
| rs7785847 | 7 | 149576818 | ATP6V0E2 | ENSG00000171130.13 | 7.938e-10 | 0 | 6761 | gtex_brain_putamen_basal |
| RS7805600 | 7 | 149577161 | ATP6V0E2 | ENSG00000171130.13 | 7.938e-10 | 0 | 7104 | gtex_brain_putamen_basal |
| RS7799585 | 7 | 149577420 | ATP6V0E2 | ENSG00000171130.13 | 7.938e-10 | 0 | 7363 | gtex_brain_putamen_basal |
| rs1133480 | 7 | 149577591 | ATP6V0E2 | ENSG00000171130.13 | 1.387E-7 | 0 | 7534 | gtex_brain_putamen_basal |
| RS67069932 | 7 | 149577936 | ATP6V0E2 | ENSG00000171130.13 | 1.199E-9 | 0 | 7879 | gtex_brain_putamen_basal |
| RS5888370 | 7 | 149578153 | ATP6V0E2 | ENSG00000171130.13 | 3.749E-10 | 0 | 8096 | gtex_brain_putamen_basal |
| RS71194666 | 7 | 149578412 | ATP6V0E2 | ENSG00000171130.13 | 1.263E-9 | 0 | 8355 | gtex_brain_putamen_basal |
| RS4725316 | 7 | 149578566 | ATP6V0E2 | ENSG00000171130.13 | 2.206E-9 | 0 | 8509 | gtex_brain_putamen_basal |
| RS199888029 | 7 | 149578674 | ATP6V0E2 | ENSG00000171130.13 | 8.502E-8 | 0 | 8617 | gtex_brain_putamen_basal |
| RS71194667 | 7 | 149578675 | ATP6V0E2 | ENSG00000171130.13 | 1.033E-10 | 0 | 8618 | gtex_brain_putamen_basal |
| RS4725838 | 7 | 149578949 | ATP6V0E2 | ENSG00000171130.13 | 5.58e-9 | 0 | 8892 | gtex_brain_putamen_basal |
| RS6977798 | 7 | 149579579 | ATP6V0E2 | ENSG00000171130.13 | 2.752E-8 | 0 | 9522 | gtex_brain_putamen_basal |
| RS4348397 | 7 | 149579787 | ATP6V0E2 | ENSG00000171130.13 | 5.28e-8 | 0 | 9730 | gtex_brain_putamen_basal |
| rs10247524 | 7 | 149579948 | ATP6V0E2 | ENSG00000171130.13 | 4.345e-10 | 0 | 9891 | gtex_brain_putamen_basal |
| RS4400299 | 7 | 149580154 | ATP6V0E2 | ENSG00000171130.13 | 1.616E-8 | 0 | 10097 | gtex_brain_putamen_basal |
| RS4394310 | 7 | 149580368 | ATP6V0E2 | ENSG00000171130.13 | 8.392E-8 | 0 | 10311 | gtex_brain_putamen_basal |
| RS6976451 | 7 | 149582747 | ATP6V0E2 | ENSG00000171130.13 | 7.823e-10 | 0 | 12690 | gtex_brain_putamen_basal |
| rs10807975 | 7 | 149583149 | ATP6V0E2 | ENSG00000171130.13 | 1.15e-8 | 0 | 13092 | gtex_brain_putamen_basal |
| rs10807976 | 7 | 149583170 | ATP6V0E2 | ENSG00000171130.13 | 1.15e-8 | 0 | 13113 | gtex_brain_putamen_basal |
| RS12540296 | 7 | 149583591 | ATP6V0E2 | ENSG00000171130.13 | 8.816e-9 | 0 | 13534 | gtex_brain_putamen_basal |
| RS11773140 | 7 | 149583794 | ATP6V0E2 | ENSG00000171130.13 | 1.081E-8 | 0 | 13737 | gtex_brain_putamen_basal |
| RS10245092 | 7 | 149584149 | ATP6V0E2 | ENSG00000171130.13 | 1.521E-8 | 0 | 14092 | gtex_brain_putamen_basal |
| rs6949457 | 7 | 149584953 | ATP6V0E2 | ENSG00000171130.13 | 1.865E-7 | 0 | 14896 | gtex_brain_putamen_basal |
| RS6949468 | 7 | 149584976 | ATP6V0E2 | ENSG00000171130.13 | 2.241E-8 | 0 | 14919 | gtex_brain_putamen_basal |
| RS34103920 | 7 | 149585304 | ATP6V0E2 | ENSG00000171130.13 | 5.025e-9 | 0 | 15247 | gtex_brain_putamen_basal |
第二节。转录组注释
一般基因表达（GTEX）
Devlopment期间的基因表达（BrainCloud）
Footnote:
总共绘制了269个时间点，n = 38个胎儿样品（x = 1：38）。每个三角形代表一个时间点。
时间变化的基因表达（brainspan）
Footnote:
SC：亚皮质区域；SM：感觉运动区域；FC：额叶皮层；和TP：颞顶皮层
ST1：胎儿（13-26个概念后周），ST2：婴儿早期至童年（4个月至11年）和ST3：青春期至成年期（13-23年）
所示的栏表示表达分布的较低25％和上层25％。