SZGR2 - Beplay体育中心

Summary?

GeneID	1555
Symbol	CYP2B6
Synonyms	CPB6\|CYP2B\|CYP2B7\|CYP2B7P\|CYPIIB6\|EFVM\|IIB1\|P450
Description	cytochrome P450 family 2 subfamily B member 6
Reference	MIM:123930\|HGNC:HGNC:2615\|Ensembl:ENSG00000197408\|HPRD:00477\|Vega:OTTHUMG00000182714
Gene type	protein-coding
Map location	19q13.2
Pascal p-value	0.964
Fetal beta	0.011

Gene in Data Sources

Gene set name	Method of gene set	Description	Info
CV:PGCnp	Genome-wide Association Study	GWAS
PMID:cooccur	High-throughput literature-search	Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
Literature	High-throughput literature-search	Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias	Click to show details

Section I. Genetics and epigenetics annotation

Section II. Transcriptome annotation

General gene expression (GTEx)

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions

Section V. Pathway annotation

Pathway name	Pathway size	# SZGR 2.0 genes in pathway	Info
KEGG ARACHIDONIC ACID METABOLISM	58	36	All SZGR 2.0 genes in this pathway
KEGG RETINOL METABOLISM	64	37	All SZGR 2.0 genes in this pathway
KEGG METABOLISM OF XENOBIOTICS BY CYTOCHROME P450	70	44	All SZGR 2.0 genes in this pathway
KEGG DRUG METABOLISM CYTOCHROME P450	72	47	All SZGR 2.0 genes in this pathway
REACTOME BIOLOGICAL OXIDATIONS	139	91	All SZGR 2.0 genes in this pathway
REACTOME XENOBIOTICS	16	11	All SZGR 2.0 genes in this pathway
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	51	34	All SZGR 2.0 genes in this pathway
REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	70	50	All SZGR 2.0 genes in this pathway
NAKAMURA TUMOR ZONE PERIPHERAL VS CENTRAL UP	285	181	All SZGR 2.0 genes in this pathway
WATANABE COLON CANCER MSI VS MSS DN	81	42	All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA UP	1821	933	All SZGR 2.0 genes in this pathway
GAUSSMANN MLL AF4 FUSION TARGETS D UP	38	23	All SZGR 2.0 genes in this pathway
萨斯博士排毒通路和致癌作用DN	13	11	All SZGR 2.0 genes in this pathway
YANG BREAST CANCER ESR1 UP	36	22	All SZGR 2.0 genes in this pathway
BYSTRYKH HEMATOPOIESIS STEM CELL QTL TRANS	882	572	All SZGR 2.0 genes in this pathway
WENG POR TARGETS GLOBAL UP	20	14	All SZGR 2.0 genes in this pathway
WENG POR DOSAGE	21	9	All SZGR 2.0 genes in this pathway
WENG POR TARGETS LIVER UP	41	29	All SZGR 2.0 genes in this pathway
MCDOWELL ACUTE LUNG INJURY DN	48	33	All SZGR 2.0 genes in this pathway
YANG MUC2 TARGETS DUODENUM 3MO DN	23	14	All SZGR 2.0 genes in this pathway
YANG MUC2 TARGETS DUODENUM 6MO DN	21	12	All SZGR 2.0 genes in this pathway
ICHIBA GRAFT VERSUS HOST DISEASE 35D DN	49	34	All SZGR 2.0 genes in this pathway
YOSHIMURA MAPK8 TARGETS UP	1305	895	All SZGR 2.0 genes in this pathway
SWEET LUNG CANCER KRAS DN	435	289	All SZGR 2.0 genes in this pathway
SHEDDEN LUNG CANCER GOOD SURVIVAL A4	196	124	All SZGR 2.0 genes in this pathway
CHIANG LIVER CANCER SUBCLASS PROLIFERATION DN	179	97	All SZGR 2.0 genes in this pathway
HOSHIDA LIVER CANCER SURVIVAL DN	113	76	All SZGR 2.0 genes in this pathway
CAIRO HEPATOBLASTOMA DN	267	160	All SZGR 2.0 genes in this pathway
GREGORY SYNTHETIC LETHAL WITH IMATINIB	145	83	All SZGR 2.0 genes in this pathway
SERVITJA LIVER HNF1A TARGETS UP	135	96	All SZGR 2.0 genes in this pathway