Gene Page:DACH1

Summary?
GeneID 1602
Symbol DACH1
Synonyms DACH
Description dachshund family transcription factor 1
参考 MIM:603803|HGNC:HGNC:2663|Ensembl:ENSG00000276644|HPRD:16031|Vega:OTTHUMG00000017063
Gene type protein-coding
Map location 13q22
Pascal p-value 2.563E-4
Sherlock p-value 0.364
eGene Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs17542473 chr4 111182451 DACH1 1602 0.18 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section III. Gene Ontology annotation

Molecular function 去的术语 Evidence Neuro keywords PubMed ID
GO:0000166 nucleotide binding IEA -
GO:0003677 DNA binding IEA -
GO:0005515 protein binding 新闻学会 14525983
Biological process 去的术语 Evidence Neuro keywords PubMed ID
GO:0006355 regulation of transcription, DNA-dependent IEA -
GO:0006350 transcription IEA -
GO:0007275 multicellular organismal development IEA -
Cellular component 去的术语 Evidence Neuro keywords PubMed ID
GO:0005634 核 IEA -

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
WATANABE COLON CANCER MSI VS MSS DN 81 42 All SZGR 2.0 genes in this pathway
SENGUPTA NASOPHARYNGEAL CARCINOMA WITH LMP1 DN 175 82 All SZGR 2.0 genes in this pathway
CHARAFE BREAST CANCER LUMINAL VS BASAL UP 380 215 All SZGR 2.0 genes in this pathway
DOANE BREAST CANCER ESR1 UP 112 72 All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 6HR UP 85 54 All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 8D DN 205 127 All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 10D DN 142 90 All SZGR 2.0 genes in this pathway
MULLIGHAN MLL SIGNATURE 1 UP 380 236 All SZGR 2.0 genes in this pathway
MULLIGHAN MLL SIGNATURE 2 UP 418 263 All SZGR 2.0 genes in this pathway
GOZGIT ESR1 TARGETS DN 781 465 All SZGR 2.0 genes in this pathway
CONCANNON APOPTOSIS BY EPOXOMICIN DN 172 112 All SZGR 2.0 genes in this pathway
BEGUM TARGETS OF PAX3 FOXO1 FUSION UP 60 45 All SZGR 2.0 genes in this pathway
FARMER BREAST CANCER BASAL VS LULMINAL 330 215 All SZGR 2.0 genes in this pathway
MARTORIATI MDM4 TARGETS NEUROEPITHELIUM DN 164 111 All SZGR 2.0 genes in this pathway
LIEN BREAST CARCINOMA METAPLASTIC VS DUCTAL DN 114 58 All SZGR 2.0 genes in this pathway
KIM MYC AMPLIFICATION TARGETS UP 201 127 All SZGR 2.0 genes in this pathway
YANG BREAST CANCER ESR1 LASER UP 34 25 All SZGR 2.0 genes in this pathway
BENPORATH SUZ12 TARGETS 1038 678 All SZGR 2.0 genes in this pathway
BENPORATH EED TARGETS 1062 725 All SZGR 2.0 genes in this pathway
BENPORATH ES WITH H3K27ME3 1118 744 All SZGR 2.0 genes in this pathway
BENPORATH PRC2 TARGETS 652 441 All SZGR 2.0 genes in this pathway
ZHANG RESPONSE TO IKK INHIBITOR AND TNF DN 103 64 All SZGR 2.0 genes in this pathway
ROSS AML WITH MLL FUSIONS 78 45 All SZGR 2.0 genes in this pathway
HADDAD T LYMPHOCYTE AND NK PROGENITOR UP 78 56 All SZGR 2.0 genes in this pathway
VERHAAK AML WITH NPM1 MUTATED DN 246 180 All SZGR 2.0 genes in this pathway
CUI TCF21 TARGETS 2 DN 830 547 All SZGR 2.0 genes in this pathway
WANG SMARCE1 TARGETS UP 280 183 All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 6HR DN 911 527 All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 24HR DN 1011 592 All SZGR 2.0 genes in this pathway
CAMPS COLON CANCER COPY NUMBER UP 92 45 All SZGR 2.0 genes in this pathway
SMID BREAST CANCER RELAPSE IN BRAIN DN 85 58 All SZGR 2.0 genes in this pathway
SMID BREAST CANCER LUMINAL B UP 172 109 All SZGR 2.0 genes in this pathway
SMID BREAST CANCER BASAL DN 701 446 All SZGR 2.0 genes in this pathway
BONOME OVARIAN CANCER SURVIVAL OPTIMAL DEBULKING 246 152 All SZGR 2.0 genes in this pathway
ROSS LEUKEMIA WITH MLL FUSIONS 78 49 All SZGR 2.0 genes in this pathway
VALK AML CLUSTER 16 26 17 All SZGR 2.0 genes in this pathway
VALK AML WITH 11Q23 REARRANGED 22 13 All SZGR 2.0 genes in this pathway
POOLA INVASIVE BREAST CANCER DN 134 83 All SZGR 2.0 genes in this pathway
HOSHIDA LIVER CANCER LATE RECURRENCE DN 69 48 All SZGR 2.0 genes in this pathway
YAGI AML WITH T 9 11 TRANSLOCATION 130 87 All SZGR 2.0 genes in this pathway
YAGI AML WITH 11Q23 REARRANGED 351 238 All SZGR 2.0 genes in this pathway
JOHNSTONE PARVB TARGETS 2 DN 336 211 All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family Target position miRNA ID miRNA seq
UTR start UTR end Match method
miR-1/206 731 737 1A hsa -miR-1 UGGAAUGUAAAGAAGUAUGUA
hsa -miR-206SZ UGGAAUGUAAGGAAGUGUGUGG
hsa -miR-613 AGGAAUGUUCCUUCUUUGCC
miR-132/212 2625 2631 1A hsa -miR-212SZ UAACAGUCUCCAGUCACGGCC
hsa -miR-132大脑 UAACAGUCUACAGCCAUGGUCG
miR-134 966 972 1A hsa -miR-134大脑 UGUGACUGGUUGACCAGAGGG
miR-138 430 436 1A hsa -miR-138大脑 AGCUGGUGUUGUGAAUC
miR-145 1326 1333 1A,m8 hsa -miR-145 GUCCAGUUUUCCCAGGAAUCCCUU
miR-15/16/195/424/497 260 266 m8 hsa -miR-15a大脑 UAGCAGCACAUAAUGGUUUGUG
hsa -miR-16大脑 UAGCAGCACGUAAAUAUUGGCG
hsa -miR-15b大脑 UAGCAGCACAUCAUGGUUUACA
hsa -miR-195SZ UAGCAGCACAGAAAUAUUGGC
hsa -miR-424 CAGCAGCAAUUCAUGUUUUGAA
hsa -miR-497 CAGCAGCACACUGUGGUUUGU
miR-153 2397 2404 1A,m8 hsa -miR-153 UUGCAUAGUCACAAAAGUGA
miR-200bc/429 971 978 1A,m8 hsa -miR-200b UAAUACUGCCUGGUAAUGAUGAC
hsa -miR-200c UAAUACUGCCGGGUAAUGAUGG
hsa -miR-429 UAAUACUGUCUGGUAAAACCGU
miR-217 845 852 1A,m8 hsa -miR-217 UACUGCAUCAGGAACUGAUUGGAU
miR-221/222 1199 1205 m8 hsa -miR-221大脑 AGCUACAUUGUCUGCUGGGUUUC
hsa -miR-222大脑 AGCUACAUCUGGCUACUGGGUCUC
miR-23 2607 2613 m8 hsa -miR-23a大脑 AUCACAUUGCCAGGGAUUUCC
hsa -miR-23b大脑 AUCACAUUGCCAGGGAUUACC
miR-30-3p 1155 1161 1A hsa -miR-30a-3p CUUUCAGUCGGAUGUUUGCAGC
hsa -miR-30e-3p CUUUCAGUCGGAUGUUUACAGC
miR-323 2607 2613 1A hsa -miR-323大脑 GCACAUUACACGGUCGACCUCU
miR-326 195 201 1A hsa -miR-326 CCUCUGGGCCCUUCCUCCAG
miR-33 2553 2559 1A hsa -miR-33 GUGCAUUGUAGUUGCAUUG
hsa -miR-33b GUGCAUUGCUGUUGCAUUGCA
miR-338 263 269 1A hsa -miR-338大脑 UCCAGCAUCAGUGAUUUUGUUGA
miR-342 2609 2615 1A hsa -miR-342大脑 UCUCACACAGAAAUCGCACCCGUC
miR-369-3p 2376 2382 1A hsa -miR-369-3p AAUAAUACAUGGUUGAUCUUU
miR-374 2376 2383 1A,m8 hsa -miR-374 UUAUAAUACAACCUGAUAAGUG
miR-376 2442 2448 1A hsa -miR-376a AUCAUAGAGGAAAAUCCACGU
hsa -miR-376b AUCAUAGAGGAAAAUCCAUGUU
miR-381 1035 1041 1A hsa - mir - 381 UAUACAAGGGCAAGCUCUCUGU
miR-382 1994 2001 1A,m8 hsa -miR-382大脑 GAAGUUGUUCGUGGUGGAUUCG
miR-384 866 872 1A hsa -miR-384 AUUCCUAGAAAUUGUUCAUA
miR-410 1721 1727 m8 hsa -miR-410 AAUAUAACACAGAUGGCCUGU
miR-448 2398 2404 1A hsa -miR-448 UUGCAUAUGUAGGAUGUCCCAU
miR-493-5p 801 807 m8 hsa -miR-493-5p UUGUACAUGGUAGGCUUUCAUU
hsa -miR-493-5p UUGUACAUGGUAGGCUUUCAUU
hsa -miR-493-5p UUGUACAUGGUAGGCUUUCAUU
hsa -miR-493-5p UUGUACAUGGUAGGCUUUCAUU
miR-496 947 954 1A,m8 hsa -miR-496 AUUACAUGGCCAAUCUC
miR-505 9 15 1A hsa -miR-505 GUCAACACUUGCUGGUUUCCUC
miR-543 2222 2228 1A hsa -miR-543 AAACAUUCGCGGUGCACUUCU
miR-7 1637 1643 m8 hsa -miR-7SZ UGGAAGACUAGUGAUUUUGUUG