Gene Page:EFNA2
Summary?
| GeneID | 1943 |
| Symbol | EFNA2 |
| Synonyms | ELF-1 | EPLG6 | HEK7-L|LERK-6|LERK6 |
| Description | ephrin-A2 |
| Reference | MIM:602756|HGNC:HGNC:3222|HPRD:04132| |
| Gene type | protein-coding |
| Map location | 19p13.3 |
| Pascal p-value | 0.007 |
| eGene | 元 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| TMEM123 | 0.83 | 0.68 |
| LOX | 0.82 | 0.40 |
| GSX2 | 0.81 | 0.39 |
| JAG1 | 0.78 | 0.74 |
| MFNG | 0.77 | 0.28 |
| TEAD1 | 0.77 | 0.73 |
| CASC5 | 0.77 | 0.23 |
| SALL1 | 0.76 | 0.70 |
| FLNC | 0.76 | 0.69 |
| MYO3A | 0.76 | 0.38 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.21 | -0.16 | -0.20 |
| SLC26A4 | -0.16 | -0.19 |
| CRYM | -0.16 | -0.18 |
| GPR22 | -0.15 | -0.15 |
| AF347015.31 | -0.15 | -0.15 |
| SYCP3 | -0.14 | -0.26 |
| USMG5 | -0.14 | -0.27 |
| MT-CO2 | -0.14 | -0.15 |
| TTC9B | -0.14 | -0.15 |
| RERGL | -0.14 | -0.13 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG AXON GUIDANCE | 129 | 103 | All SZGR 2.0 genes in this pathway |
| PID EPHA FWDPATHWAY | 34 | 29 | All SZGR 2.0 genes in this pathway |
| BOGNI TREATMENT RELATED MYELOID LEUKEMIA UP | 30 | 19 | All SZGR 2.0 genes in this pathway |
| ABBUD LIF SIGNALING 1 DN | 26 | 17 | All SZGR 2.0 genes in this pathway |
| GUO HEX TARGETS UP | 81 | 54 | All SZGR 2.0 genes in this pathway |
| HASLINGER B CLL WITH 13Q14 DELETION | 24 | 18 | All SZGR 2.0 genes in this pathway |
| KAAB FAILED HEART ATRIUM UP | 38 | 30 | All SZGR 2.0 genes in this pathway |
| VART KSHV INFECTION ANGIOGENIC MARKERS UP | 165 | 118 | All SZGR 2.0 genes in this pathway |
| MEISSNER NPC HCP WITH H3K4ME2 | 491 | 319 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN MCV6 HCP WITH H3K27ME3 | 435 | 318 | All SZGR 2.0 genes in this pathway |
| MARTENS TRETINOIN RESPONSE UP | 857 | 456 | All SZGR 2.0 genes in this pathway |
| BRUINS UVC RESPONSE VIA TP53 GROUP D | 280 | 158 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY | 1725 | 838 | All SZGR 2.0 genes in this pathway |