基因Page:EGR2

Summary?
基因ID 1959
象征 EGR2
同义词 AT591 | CMT1D | CMT4E | KROX20
Description early growth response 2
Reference MIM:129010|HGNC：HGNC：3239|ENSEMBL：ENSG00000122877|HPRD:00551|Vega:OTTHUMG00000018308
基因类型 protein-coding
Map location 10q21.1
Pascal P值 0.061
Fetal beta -1.595
eGene Myers' cis & trans

基因in Data Sources
基因set name 基因组方法 Description Info
简历：PGCNP Genome-wide Association Study GWAS
PMID:cooccur High-throughput literature-search Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
Literature High-throughput literature-search Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophrenias 点击to show details
GO_Annotation Mapping neuro-related keywords to Gene Ontology annotations 与神经相关的关键字的命中：1

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome 位置 eGene 基因Entrez ID pvalue qvalue TSS distance eQTL type
rs16918799 CHR10 65464025 EGR2 1959 0.14 cis
rs307378 0 EGR2 1959 0.19 trans
rs6677917 CHR1 34406841 EGR2 1959 0.14 trans
rs983619 CHR1 39047418 EGR2 1959 0.05 trans
RS7545984 CHR1 45003892 EGR2 1959 0.01 trans
rs7554123 CHR1 45004203 EGR2 1959 0.01 trans
rs12059674 CHR1 57630277 EGR2 1959 0.02 trans
rs17126801 CHR1 65098162 EGR2 1959 0.02 trans
RS17474410 CHR1 68267242 EGR2 1959 0.14 trans
rs7511937 0 EGR2 1959 0 trans
rs2782784 CHR1 71195282 EGR2 1959 0.01 trans
RS2257700 CHR1 71273516 EGR2 1959 0.05 trans
rs7541092 CHR1 71362471 EGR2 1959 0.09 trans
rs17689089 CHR1 77740105 EGR2 1959 0 trans
rs17100231 CHR1 77761339 EGR2 1959 0.01 trans
rs17100274 CHR1 77774412 EGR2 1959 3.806E-5 trans
rs12034005 CHR1 79793034 EGR2 1959 0.04 trans
rs3015033 CHR1 79847235 EGR2 1959 0.01 trans
RS17098656 CHR1 80098386 EGR2 1959 0.01 trans
RS6664544 CHR1 92524192 EGR2 1959 0 trans
RS12403481 CHR1 109503655 EGR2 1959 0 trans
rs337294 0 EGR2 1959 0.02 trans
rs17029293 CHR1 112567844 EGR2 1959 2.975E-4 trans
rs16837984 CHR1 157042626 EGR2 1959 0 trans
rs16837989 CHR1 157046286 EGR2 1959 0.01 trans
rs16838012 CHR1 157048974 EGR2 1959 0 trans
rs16838014 0 EGR2 1959 0 trans
rs4657385 CHR1 164939279 EGR2 1959 0.14 trans
RS6666937 CHR1 170286842 EGR2 1959 8.539E-4 trans
rs12071422 CHR1 185573879 EGR2 1959 0.01 trans
rs16843112 CHR1 198420657 EGR2 1959 0.19 trans
rs697455 CHR1 202512075 EGR2 1959 0.02 trans
rs4457633 CHR1 204283819 EGR2 1959 0.04 trans
rs3748669 CHR1 207077022 EGR2 1959 0.01 trans
rs6673109 CHR1 207253132 EGR2 1959 9.237E-5 trans
rs17260245 CHR1 209411024 EGR2 1959 0.17 trans
rs1796829 CHR1 239661818 EGR2 1959 3.155E-4 trans
RS12034521 CHR1 239717679 EGR2 1959 1.996E-5 trans
rs6670526 CHR1 239725414 EGR2 1959 0.16 trans
snp_a-1990354 0 EGR2 1959 9.225E-7 trans
rs939217 CHR2 12730751 EGR2 1959 0.03 trans
RS6432434 CHR2 14160930 EGR2 1959 0 trans
rs6712107 CHR2 14178653 EGR2 1959 0.03 trans
rs16861129 CHR2 14201738 EGR2 1959 0.03 trans
rs16861131 CHR2 14202085 EGR2 1959 0.03 trans
rs7589712 CHR2 14205064 EGR2 1959 0.14 trans
rs12329305 CHR2 19552912 EGR2 1959 0 trans
rs12611832 CHR2 31196248 EGR2 1959 0.02 trans
RS12614732 CHR2 31199913 EGR2 1959 0.02 trans
rs17023938 CHR2 39773236 EGR2 1959 0.18 trans
RS7560081 CHR2 62793238 EGR2 1959 0 trans
rs17029079 CHR2 64736071 EGR2 1959 0.01 trans
rs17038084 CHR2 85192280 EGR2 1959 4.202E-5 trans
RS17024035 CHR2 100968559 EGR2 1959 0.06 trans
rs7574684 CHR2 100992911 EGR2 1959 0.06 trans
rs17024129 CHR2 100995144 EGR2 1959 0.06 trans
rs7585898 CHR2 100998292 EGR2 1959 0.06 trans
rs1370627 CHR2 101009384 EGR2 1959 0.06 trans
RS17042517 CHR2 113639583 EGR2 1959 0.18 trans
rs17047906 CHR2 119007824 EGR2 1959 0.12 trans
rs1840209 CHR2 125625401 EGR2 1959 0.02 trans
RS6707117 CHR2 136855504 EGR2 1959 2.06E-12 trans
rs17834293 CHR2 142993878 EGR2 1959 0.14 trans
rs7564795 CHR2 143033291 EGR2 1959 0.09 trans
rs10189091 CHR2 143471999 EGR2 1959 9.547E-4 trans
SNP_A-2198363 0 EGR2 1959 0.01 trans
rs707097 CHR2 155318814 EGR2 1959 0.03 trans
RS16838911 CHR2 156087569 EGR2 1959 3.899E-4 trans
RS12469388 CHR2 178689030 EGR2 1959 0.19 trans
rs7608942 CHR2 182820100 EGR2 1959 0.03 trans
rs16848675 CHR2 21334996 EGR2 1959 0.04 trans
rs16829292 CHR2 233447622 EGR2 1959 0.01 trans
rs16829401 CHR2 233538391 EGR2 1959 0 trans
rs17040622 CHR3 4440673 EGR2 1959 0.01 trans
RS17684934 CHR3 4443547 EGR2 1959 1.114E-4 trans
rs17040633 CHR3 4446836 EGR2 1959 1.114E-4 trans
RS17756483 CHR3 4451309 EGR2 1959 1.114E-4 trans
rs17685441 CHR3 4465165 EGR2 1959 1.114E-4 trans
rs17015415 CHR3 24933888 EGR2 1959 0.03 trans
RS12639503 CHR3 51860816 EGR2 1959 0.06 trans
RS9863778 CHR3 55375950 EGR2 1959 0.02 trans
rs997245 CHR3 61844600 EGR2 1959 8.765e-4 trans
rs3796213 CHR3 69157380 EGR2 1959 0.05 trans
rs6549186 CHR3 69211954 EGR2 1959 0.07 trans
rs2875492 CHR3 86006209 EGR2 1959 0.01 trans
rs16843128 CHR3 100713413 EGR2 1959 6.137E-4 trans
rs1381835 CHR3 110600595 EGR2 1959 0 trans
rs1877965 CHR3 126013904 EGR2 1959 0.15 trans
rs9289277 CHR3 126038339 EGR2 1959 0.1 trans
rs16839796 CHR4 7188348 EGR2 1959 7.519E-5 trans
RS4631023 CHR4 8101794 EGR2 1959 0.07 trans
rs7684087 CHR4 21673380 EGR2 1959 0.01 trans
RS16989064 CHR4 33639397 EGR2 1959 0 trans
rs11096966 CHR4 38961258 EGR2 1959 0.13 trans
rs4469113 CHR4 41461062 EGR2 1959 2.509E-4 trans
RS6836259 CHR4 57173074 EGR2 1959 0.06 trans
RS2643038 CHR4 62313218 EGR2 1959 0.01 trans
snp_a-1830437 0 EGR2 1959 0.15 trans
rs6817626 CHR4 78005836 EGR2 1959 0.04 trans
RS1604153 CHR4 78472744 EGR2 1959 0.02 trans
rs1564462 CHR4 79910988 EGR2 1959 0.08 trans
RS6827713 CHR4 79936877 EGR2 1959 0.02 trans
rs17005000 CHR4 81826551 EGR2 1959 0.04 trans
RS10011751 CHR4 93984994 EGR2 1959 0.01 trans
RS11099888 CHR4 154498555 EGR2 1959 0.07 trans
RS17701328 CHR4 178744532 EGR2 1959 0.17 trans
rs6881821 CHR5 8578465 EGR2 1959 8.795e-5 trans
rs9312843 CHR5 13802997 EGR2 1959 0 trans
rs1732944 CHR5 30905595 EGR2 1959 0.11 trans
RS1697073 CHR5 30907267 EGR2 1959 0.01 trans
rs9292700 CHR5 38192610 EGR2 1959 0.18 trans
rs2115110 CHR5 38193428 EGR2 1959 1.764E-5 trans
RS16873956 CHR5 44312488 EGR2 1959 0 trans
RS10040715 CHR5 57594207 EGR2 1959 5.105E-11 trans
rs16894149 CHR5 61013724 EGR2 1959 0.1 trans
snp_a-4217300 0 EGR2 1959 1.213E-6 trans
RS1862599 CHR5 82095088 EGR2 1959 0 trans
rs163953 CHR5 92289536 EGR2 1959 0.01 trans
rs17134275 CHR5 100634998 EGR2 1959 0 trans
RS17257221 CHR5 101016609 EGR2 1959 0.07 trans
rs10063272 CHR5 103540974 EGR2 1959 0.1 trans
rs2963232 CHR5 103713882 EGR2 1959 0.02 trans
rs250323 CHR5 115646995 EGR2 1959 0.03 trans
rs1350578 CHR5 116310282 EGR2 1959 0.02 trans
RS2900115 CHR5 117414349 EGR2 1959 0.11 trans
RS11955842 CHR5 118066618 EGR2 1959 0.04 trans
rs6894229 CHR5 127160990 EGR2 1959 0.18 trans
rs2141482 CHR5 136760477 EGR2 1959 8.057E-5 trans
snp_a-1983671 0 EGR2 1959 0.18 trans
rs2189803 CHR5 137684661 EGR2 1959 1.274E-8 trans
RS17063216 CHR5 163777647 EGR2 1959 0.02 trans
RS17063224 CHR5 163780687 EGR2 1959 0.02 trans
RS17666252 CHR5 168294345 EGR2 1959 0.19 trans
snp_a-2055204 0 EGR2 1959 0.04 trans
RS259913 CHR5 169370782 EGR2 1959 1.629E-5 trans
snp_a-2275210 0 EGR2 1959 0.17 trans
rs2116811 CHR5 171820051 EGR2 1959 3.122E-4 trans
rs258875 CHR5 173046554 EGR2 1959 0.05 trans
rs16883859 CHR6 20474617 EGR2 1959 0.09 trans
rs16883862 CHR6 20474766 EGR2 1959 0.09 trans
RS10484635 CHR6 20538664 EGR2 1959 0.05 trans
rs7747254 CHR6 24013530 EGR2 1959 0.14 trans
rs3909134 CHR6 29699252 EGR2 1959 0.13 trans
rs195429 CHR6 37354434 EGR2 1959 0.01 trans
rs16890522 CHR6 38236301 EGR2 1959 0.16 trans
rs12528414 CHR6 38404800 EGR2 1959 0.03 trans
rs7764900 CHR6 38440495 EGR2 1959 0.08 trans
rs6915776 CHR6 71797961 EGR2 1959 0.19 trans
RS17069168 CHR6 108335432 EGR2 1959 0.11 trans
RS17069171 CHR6 108335593 EGR2 1959 0.05 trans
RS391196 CHR6 111563907 EGR2 1959 0.06 trans
rs4289676 CHR6 123999302 EGR2 1959 7.47E-4 trans
rs17055235 CHR6 128355263 EGR2 1959 0.06 trans
rs2030024 CHR6 131014624 EGR2 1959 0 trans
RS9402280 CHR6 131102770 EGR2 1959 0.01 trans
rs17062925 CHR6 134168614 EGR2 1959 0.18 trans
rs7767456 CHR6 134356119 EGR2 1959 0.03 trans
rs9385758 CHR6 136729593 EGR2 1959 0.19 trans
rs12176346 CHR6 136732663 EGR2 1959 0 trans
rs9402819 CHR6 136848169 EGR2 1959 0.02 trans
rs9389400 CHR6 136854803 EGR2 1959 0.02 trans
rs2237264 CHR6 136919977 EGR2 1959 0 trans
rs17080121 CHR6 151009189 EGR2 1959 0 trans
RS12529269 CHR6 153543829 EGR2 1959 0 trans
rs10872699 CHR6 153544252 EGR2 1959 4.044e-5 trans
rs1321606 CHR6 153545278 EGR2 1959 0 trans
rs10945911 CHR6 164047509 EGR2 1959 1.075E-4 trans
rs17156078 CHR7 27988688 EGR2 1959 0 trans
rs12701006 CHR7 30147298 EGR2 1959 1.07E-6 trans
rs1156490 CHR7 34334956 EGR2 1959 0.17 trans
rs1419793 CHR7 34697630 EGR2 1959 0.19 trans
rs17815964 CHR7 52540908 EGR2 1959 0.04 trans
RS17621151 CHR7 53572911 EGR2 1959 1.204E-4 trans
RS10245449 CHR7 80935100 EGR2 1959 0.01 trans
RS2272618 CHR7 107871360 EGR2 1959 0.13 trans
RS12669568 CHR7 107885942 EGR2 1959 0.13 trans
rs7777322 CHR7 107886663 EGR2 1959 0.13 trans
RS12671672 CHR7 117614219 EGR2 1959 0.03 trans
rs10487383 CHR7 117671737 EGR2 1959 0 trans
rs6958821 CHR7 153253566 EGR2 1959 0 trans
RS1865462 CHR7 157637961 EGR2 1959 0.12 trans
rs11779237 CHR8 1227664 EGR2 1959 0.01 trans
rs1358128 CHR8 5268072 EGR2 1959 0.01 trans
rs12682256 CHR8 5306138 EGR2 1959 0.01 trans
rs1010895 CHR8 14580230 EGR2 1959 0.02 trans
RS10109456 CHR8 19565941 EGR2 1959 0.01 trans
rs17054681 CHR8 25814323 EGR2 1959 0.07 trans
rs16877914 CHR8 31196384 EGR2 1959 0.08 trans
rs1457044 CHR8 59257567 EGR2 1959 4.062E-7 trans
rs1457032 CHR8 59290536 EGR2 1959 4.955E-5 trans
rs2680903 CHR8 59512333 EGR2 1959 0.04 trans
RS2634533 CHR8 59535621 EGR2 1959 0.06 trans
rs7465259 0 EGR2 1959 0.01 trans
rs10104622 CHR8 63333773 EGR2 1959 0.01 trans
RS2218911 CHR8 63371015 EGR2 1959 0.01 trans
rs1551199 CHR8 63388117 EGR2 1959 0.01 trans
rs1733950 CHR8 90062516 EGR2 1959 2.51E-10 trans
rs1240028 CHR8 90093357 EGR2 1959 1.261E-4 trans
rs1240087 CHR8 90113945 EGR2 1959 5.906E-4 trans
rs318307 CHR8 90185459 EGR2 1959 1.775E-4 trans
rs1483373 CHR8 90186442 EGR2 1959 0.02 trans
RS11776005 CHR8 90187416 EGR2 1959 0 trans
rs1159499 CHR8 90196948 EGR2 1959 0.01 trans
rs1355060 CHR8 118717710 EGR2 1959 0 trans
rs2280828 CHR8 118762435 EGR2 1959 0 trans
RS17683401 CHR8 119671834 EGR2 1959 0.16 trans
rs16901935 CHR8 128076544 EGR2 1959 0.07 trans
rs4976941 CHR8 142744439 EGR2 1959 3.33E-5 trans
rs9298651 Chr9 10076275 EGR2 1959 1.259E-5 trans
rs16931013 Chr9 10076859 EGR2 1959 1.259E-5 trans
RS1467547 Chr9 17630726 EGR2 1959 0.01 trans
rs4415417 Chr9 17837857 EGR2 1959 0.06 trans
rs2210327 Chr9 18109234 EGR2 1959 0.03 trans
rs6476383 Chr9 32865568 EGR2 1959 0.02 trans
rs11143622 Chr9 71370050 EGR2 1959 0.01 trans
rs11143868 Chr9 71437411 EGR2 1959 0.06 trans
rs11143995 Chr9 71462852 EGR2 1959 0.06 trans
rs11144031 Chr9 71477107 EGR2 1959 0.06 trans
RS11791891 Chr9 87512411 EGR2 1959 0.01 trans
rs2165893 Chr9 87531423 EGR2 1959 0 trans
RS763623 Chr9 87539663 EGR2 1959 0.12 trans
RS3780642 Chr9 87553144 EGR2 1959 6.457E-6 trans
rs10992752 Chr9 96240578 EGR2 1959 0.01 trans
rs10981864 Chr9 116416735 EGR2 1959 0.1 trans
snp_a-1879318 0 EGR2 1959 0.09 trans
RS2807706 Chr9 121744331 EGR2 1959 2.853E-4 trans
rs2818297 Chr9 121757015 EGR2 1959 0.01 trans
RS10739527 Chr9 121772512 EGR2 1959 0.01 trans
rs6537944 Chr9 137312827 EGR2 1959 0.02 trans
rs11103132 Chr9 138575901 EGR2 1959 0.01 trans
rs1017361 CHR10 294952 EGR2 1959 0.16 trans
rs6560840 CHR10 489655 EGR2 1959 0.03 trans
rs11252514 CHR10 499572 EGR2 1959 8.532E-4 trans
rs2924269 CHR10 4884783 EGR2 1959 0.13 trans
rs11014370 CHR10 25352798 EGR2 1959 0.02 trans
rs772394 CHR10 35980024 EGR2 1959 0 trans
rs17432714 CHR10 43526022 EGR2 1959 0.05 trans
rs2853836 CHR10 48431948 EGR2 1959 0.02 trans
rs1908351 CHR10 57877117 EGR2 1959 0 trans
rs3104871 CHR10 57878502 EGR2 1959 7.348E-5 trans
rs901309 CHR10 72571899 EGR2 1959 0.01 trans
rs4750827 CHR10 132547183 EGR2 1959 0.03 trans
rs4750829 CHR10 132547260 EGR2 1959 0.04 trans
rs11021918 CHR11 2269189 EGR2 1959 0.01 trans
rs862785 CHR11 20175604 EGR2 1959 0.02 trans
RS16911034 CHR11 23302320 EGR2 1959 0 trans
rs10838551 CHR11 46073112 EGR2 1959 0.09 trans
rs10838567 CHR11 46136342 EGR2 1959 0.09 trans
rs12292520 CHR11 48086150 EGR2 1959 0.07 trans
RS17142688 CHR11 81319064 EGR2 1959 0.07 trans
RS619320 CHR11 81846219 EGR2 1959 0.13 trans
RS11020043 CHR11 92470587 EGR2 1959 0.06 trans
rs2460047 CHR11 93678935 EGR2 1959 0.18 trans
rs1789300 CHR11 95463631 EGR2 1959 4.92E-4 trans
RS1727152 CHR11 95467435 EGR2 1959 0.02 trans
rs1255149 CHR11 95484493 EGR2 1959 4.64E-4 trans
rs3748251 CHR11 95519156 EGR2 1959 1.302E-4 trans
rs16922543 CHR11 95526116 EGR2 1959 1.302E-4 trans
rs16922622 CHR11 95567387 EGR2 1959 1.302E-4 trans
rs3181323 CHR11 104878386 EGR2 1959 0.01 trans
rs11219092 CHR11 123130750 EGR2 1959 0.05 trans
RS7119608 CHR11 134922824 EGR2 1959 0.08 trans
RS766095 CHR12 1498432 EGR2 1959 0.15 trans
RS2109556 CHR12 3887300 EGR2 1959 0.14 trans
rs733593 CHR12 6636391 EGR2 1959 0.01 trans
RS2058798 CHR12 16743164 EGR2 1959 0.12 trans
rs374484 CHR12 27627159 EGR2 1959 8.488e-4 trans
rs451921 CHR12 27627499 EGR2 1959 0.11 trans
rs10771436 CHR12 28744556 EGR2 1959 0.06 trans
RS1344796 CHR12 76397104 EGR2 1959 3.074E-4 trans
rs11831213 CHR12 109895355 EGR2 1959 0.11 trans
rs10850201 CHR12 109903061 EGR2 1959 0 trans
RS7133714 CHR12 120141546 EGR2 1959 0.08 trans
RS11833075 CHR12 122114592 EGR2 1959 9.326E-5 trans
RS1041050 CHR13 26585121 EGR2 1959 0.01 trans
rs9581602 CHR13 26834548 EGR2 1959 0.03 trans
RS17084271 CHR13 27089799 EGR2 1959 0.03 trans
RS17084280 CHR13 27090872 EGR2 1959 0.03 trans
RS9569893 CHR13 34198563 EGR2 1959 0.09 trans
RS2408301 CHR13 51808915 EGR2 1959 0.08 trans
rs7982110 CHR13 59723428 EGR2 1959 6.427E-4 trans
rs9528250 CHR13 61410190 EGR2 1959 0 trans
rs7330331 CHR13 67403122 EGR2 1959 5.763E-4 trans
rs17088392 CHR13 72257235 EGR2 1959 0.04 trans
RS7327697 CHR13 83227456 EGR2 1959 7.968E-5 trans
RS17667894 CHR13 92014308 EGR2 1959 0 trans
rs223110 CHR14 23973042 EGR2 1959 0.08 trans
rs7156088 CHR14 27821865 EGR2 1959 6.427E-4 trans
rs8013705 CHR14 34853284 EGR2 1959 0.08 trans
rs17106703 CHR14 37851979 EGR2 1959 0.16 trans
rs7147321 CHR14 45877904 EGR2 1959 0.01 trans
rs1952728 CHR14 45893091 EGR2 1959 0.01 trans
RS17116137 CHR14 45940865 EGR2 1959 0.01 trans
rs7151829 CHR14 45971281 EGR2 1959 0.01 trans
rs8022005 CHR14 61345380 EGR2 1959 0 trans
rs17100844 CHR14 63669261 EGR2 1959 0.12 trans
RS10148418 CHR14 67003872 EGR2 1959 0 trans
rs149642 CHR14 72653498 EGR2 1959 0.02 trans
RS3861624 CHR14 78416193 EGR2 1959 0.07 trans
rs941539 CHR14 93561214 EGR2 1959 0.05 trans
rs1885073 CHR14 104357181 EGR2 1959 3.959E-6 trans
rs4465541 CHR14 105016846 EGR2 1959 0.09 trans
rs16973929 CHR15 47395709 EGR2 1959 0.01 trans
RS8039808 CHR15 49939845 EGR2 1959 0.09 trans
rs10518936 CHR15 58090522 EGR2 1959 0.04 trans
rs2414703 CHR15 61904602 EGR2 1959 0.01 trans
rs289171 CHR15 62576053 EGR2 1959 5.831E-4 trans
rs289161 CHR15 62589888 EGR2 1959 9.705E-4 trans
RS939043 CHR15 70236428 EGR2 1959 0.19 trans
RS11858762 CHR15 81386594 EGR2 1959 0.03 trans
rs9635390 CHR15 90809632 EGR2 1959 2.566E-5 trans
rs7174562 CHR15 93811530 EGR2 1959 0.07 trans
rs16948359 CHR15 94233206 EGR2 1959 0.19 trans
rs16948375 CHR15 94236354 EGR2 1959 0.03 trans
rs17140355 CHR16 6548831 EGR2 1959 0.12 trans
rs8047151 CHR16 17209696 EGR2 1959 1.871E-7 trans
rs4271578 CHR16 17213886 EGR2 1959 4.061E-6 trans
rs7200513 CHR16 17219474 EGR2 1959 0.01 trans
RS3829495 CHR16 17221986 EGR2 1959 5.763E-4 trans
rs7193763 CHR16 17225534 EGR2 1959 5.351E-5 trans
rs11861635 CHR16 82543377 EGR2 1959 0.03 trans
rs276966 CHR16 86233753 EGR2 1959 0.03 trans
rs643099 CHR17 6568815 EGR2 1959 0.19 trans
rs1867231 CHR17 13678834 EGR2 1959 0.06 trans
RS9903086 CHR17 39949515 EGR2 1959 0.16 trans
rs7219986 CHR17 53263206 EGR2 1959 0 trans
rs17817797 CHR17 53332496 EGR2 1959 9.358E-4 trans
rs16951770 CHR18 7444826 EGR2 1959 0.01 trans
RS2851752 CHR18 25350684 EGR2 1959 0.11 trans
RS7244394 CHR18 32223105 EGR2 1959 0.02 trans
snp_a-4248697 0 EGR2 1959 0.02 trans
rs16951384 CHR18 47527116 EGR2 1959 0.08 trans
RS10502924 CHR18 49172178 EGR2 1959 0.12 trans
rs17064695 CHR18 55956427 EGR2 1959 0.05 trans
rs1469489 CHR18 57228488 EGR2 1959 0.15 trans
rs1469490 CHR18 57229886 EGR2 1959 0.11 trans
rs17074993 CHR18 63260128 EGR2 1959 0.01 trans
snp_a-1821751 0 EGR2 1959 0 trans
rs1942461 CHR18 70509159 EGR2 1959 0.01 trans
rs1942462 CHR18 70509823 EGR2 1959 0.01 trans
rs1942463 CHR18 70509841 EGR2 1959 0.01 trans
rs1942464 CHR18 70509877 EGR2 1959 2.489E-4 trans
rs1942466 CHR18 70517154 EGR2 1959 0.01 trans
rs2156494 CHR18 70518084 EGR2 1959 0.01 trans
RS17056922 CHR18 73086804 EGR2 1959 0.01 trans
rs1540047 CHR18 75047028 EGR2 1959 0.07 trans
rs2850843 CHR18 75048905 EGR2 1959 0.07 trans
rs1540051 CHR18 75049934 EGR2 1959 0.02 trans
rs16980096 CHR19 15000921 EGR2 1959 0.07 trans
snp_a-2138575 0 EGR2 1959 0 trans
RS8103530 CHR19 39172219 EGR2 1959 0.13 trans
RS234337 CHR19 40458724 EGR2 1959 0 trans
RS234363 CHR19 40474607 EGR2 1959 5.133E-4 trans
RS634346 CHR20 3587203 EGR2 1959 0.19 trans
rs6417634 CHR20 6408617 EGR2 1959 0.15 trans
rs6085552 CHR20 6409004 EGR2 1959 0.15 trans
rs16997215 CHR20 16101890 EGR2 1959 0.02 trans
snp_a-4254460 0 EGR2 1959 0.02 trans
rs8113962 CHR20 18995999 EGR2 1959 0.13 trans
RS1797040 CHR20 23907743 EGR2 1959 0.01 trans
RS2424603 0 EGR2 1959 0.01 trans
RS6102879 CHR20 41138766 EGR2 1959 0.02 trans
rs6026122 CHR20 56769083 EGR2 1959 7.113E-4 trans
rs259991 CHR20 57728347 EGR2 1959 0.06 trans
rs6015452 CHR20 57782312 EGR2 1959 0.04 trans
RS6124034 CHR20 59517206 EGR2 1959 0.04 trans
RS6124036 CHR20 59517478 EGR2 1959 0.04 trans
rs4812237 CHR20 59518040 EGR2 1959 0.01 trans
rs2847443 CHR21 14595263 EGR2 1959 0.05 trans
rs2226440 CHR21 18066174 EGR2 1959 0.1 trans
rs16992859 CHR21 36507007 EGR2 1959 0.02 trans
RS2834872 CHR21 36634845 EGR2 1959 0.01 trans
RS2834874 CHR21 36641270 EGR2 1959 0.04 trans
RS2834875 CHR21 36656119 EGR2 1959 0 trans
RS877910 CHR21 36658376 EGR2 1959 0.01 trans
rs7284012 CHR21 36664376 EGR2 1959 0.07 trans
rs6586271 CHR21 44362641 EGR2 1959 0.03 trans
rs369613 CHR22 22380717 EGR2 1959 0.06 trans
rs410285 CHR22 22381767 EGR2 1959 0.06 trans
rs134028 CHR22 28048448 EGR2 1959 1.896E-5 trans
rs5762317 CHR22 28094988 EGR2 1959 0 trans
rs9968025 CHR22 32321588 EGR2 1959 0.04 trans
rs5768165 CHR22 48318197 EGR2 1959 0.03 trans
rs5768168 CHR22 48319334 EGR2 1959 0.03 trans
rs5768173 CHR22 48321475 EGR2 1959 0.03 trans
rs16978981 Chrx 13538144 EGR2 1959 0.19 trans
rs7879159 Chrx 19481591 EGR2 1959 0.1 trans
RS12006821 Chrx 50424687 EGR2 1959 0.02 trans
rs5977652 Chrx 131315199 EGR2 1959 0.15 trans
rs16992781 Chrx 146460376 EGR2 1959 0.02 trans
RS4824295 Chrx 146496881 EGR2 1959 0.01 trans

Section II. Transcriptome annotation

基因ral gene expression (GTEx)

Not available

Devlopment期间的基因表达（BrainCloud）

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

基因expression of temporal and spatial changes (BrainSpan)

Footnote:
SC:分皮质区域;SM:感觉运动区域s; FC: frontal cortex; and TP: temporal-parietal cortex
ST1：胎儿（13-26个概念后周），ST2：婴儿早期至童年（4个月至11年）和ST3：青春期至成年期（13-23年）
所示的栏表示表达分布的较低25％和上层25％。

大脑区域的顶级共表达基因

Top 10 positively co-expressed genes
基因 皮尔逊的相关性 斯皮尔曼的相关性
PMPCB 0.89 0.85
UQCRC2 0.88 0.85
DNAJA2 0.88 0.84
YPEL5 0.88 0.87
polr3f 0.87 0.85
BTBD10 0.87 0.87
SARS 0.87 0.86
TMEM49 0.87 0.84
COPS3 0.86 0.83
RHOT1 0.86 0.83
前10个负共表达基因
基因 皮尔逊的相关性 斯皮尔曼的相关性
AF347015.2 -0.67 -0.59
AF347015.26 -0.67 -0.59
MT-CO2 -0.66 -0.57
AF347015.8 -0.65 -0.57
MT-CYB -0.65 -0.57
AF347015.15 -0.64 -0.57
AF347015.33 -0.63 -0.57
AF347015.21 -0.63 -0.55
AF347015.18 -0.63 -0.63
AF347015.31 -0.62 -0.56

Section III. Gene Ontology annotation

Molecular function 去的术语 Evidence Neuro keywords PubMed ID
GO:0003700 转录factor activity IDA 14532282
GO:0005515 protein binding IPI 14532282
去：0008270 锌离子结合 IEA -
GO:0046872 metal ion binding IEA -
Biological process 去的术语 Evidence Neuro keywords PubMed ID
去：0007420 brain development TAS Brain (GO term level: 7) 9537424
去：0006355 regulation of transcription, DNA-dependent IEA -
去：0006350 转录 IEA -
去：0007422 peripheral nervous system development TAS 9537424
去：0007638 mechanosensory behavior IEA -
蜂窝组件 去的术语 Evidence Neuro keywords PubMed ID
GO:0005622 intracellular IEA -
GO:0005634 nucleus IEA -

Section V. Pathway annotation

路径名 Pathway size # SZGR 2.0 genes in pathway Info
BIOCARTA VIP PATHWAY 29 26 All SZGR 2.0 genes in this pathway
ST DIFFERENTIATION PATHWAY IN PC12 CELLS 45 35 All SZGR 2.0 genes in this pathway
PID IL4 2PATHWAY 65 43 All SZGR 2.0 genes in this pathway
PID NFAT TFPATHWAY 47 39 All SZGR 2.0 genes in this pathway
PID TAP63途径 54 40 All SZGR 2.0 genes in this pathway
REACTOME DEVELOPMENTAL BIOLOGY 396 292 All SZGR 2.0 genes in this pathway
白色脂肪细胞分化的Reactome转录调节 72 53 All SZGR 2.0 genes in this pathway
钟对偶氮替丁的反应和tsa 183 119 All SZGR 2.0 genes in this pathway
GAL LEUKEMIC STEM CELL DN 244 153 All SZGR 2.0 genes in this pathway
胶原蛋白凝胶中的Oswald造血干细胞 233 161 All SZGR 2.0 genes in this pathway
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION HSC UP 185 126 All SZGR 2.0 genes in this pathway
NAGASHIMA NRG1 SIGNALING UP 176 123 All SZGR 2.0 genes in this pathway
NAGASHIMA EGF SIGNALING UP 58 40 All SZGR 2.0 genes in this pathway
甲状腺癌变性DN 537 339 All SZGR 2.0 genes in this pathway
HAHTOLA MYCOSIS FUNGOIDES CD4 UP 64 46 All SZGR 2.0 genes in this pathway
ENK UV RESPONSE EPIDERMIS DN 508 354 All SZGR 2.0 genes in this pathway
GESERICK TERT TARGETS DN 21 16 All SZGR 2.0 genes in this pathway
DELYS THYROID CANCER DN 232 154 All SZGR 2.0 genes in this pathway
绿草SMANN APOPTOSIS BY DOXORUBICIN UP 1142 669 All SZGR 2.0 genes in this pathway
绿草SMANN RESPONSE TO MC AND DOXORUBICIN UP 612 367 All SZGR 2.0 genes in this pathway
GAUSSMANN MLL AF4 FUSION TARGETS G UP 238 135 All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL BREAST 3 4WK UP 214 144 All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL BREAST 4 5WK UP 271 175 All SZGR 2.0 genes in this pathway
McBryan Pubertal乳房6 7WK DN 79 54 All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL TGFB1 TARGETS UP 169 127 All SZGR 2.0 genes in this pathway
McBryan终端末端芽 12 12 All SZGR 2.0 genes in this pathway
汇款皮肤伤口 10 9 All SZGR 2.0 genes in this pathway
Perez TP53目标 1174 695 All SZGR 2.0 genes in this pathway
Perez TP63目标 355 243 All SZGR 2.0 genes in this pathway
Perez TP53和TP63目标 205 145 All SZGR 2.0 genes in this pathway
dirmeier LMP1响应早期 66 48 All SZGR 2.0 genes in this pathway
DAWSON METHYLATED IN LYMPHOMA TCL1 59 45 All SZGR 2.0 genes in this pathway
NUYTTEN NIPP1 TARGETS UP 769 437 All SZGR 2.0 genes in this pathway
NUYTTEN EZH2 TARGETS UP 1037 673 All SZGR 2.0 genes in this pathway
Benporath Suz12目标 1038 678 All SZGR 2.0 genes in this pathway
与H3K27me3的Benporath ES 1118 744 All SZGR 2.0 genes in this pathway
KIM GERMINAL CENTER T HELPER UP 66 42 All SZGR 2.0 genes in this pathway
Jechlinger上皮到间充质转变DN 66 47 All SZGR 2.0 genes in this pathway
ZHANG TARGETS OF EWSR1 FLI1 FUSION 88 68 All SZGR 2.0 genes in this pathway
GALINDO IMMUNE RESPONSE TO ENTEROTOXIN 85 67 All SZGR 2.0 genes in this pathway
HESS TARGETS OF HOXA9 AND MEIS1 DN 77 48 All SZGR 2.0 genes in this pathway
STAEGE EWING FAMILY TUMOR 33 22 All SZGR 2.0 genes in this pathway
江龄大脑皮层 36 27 All SZGR 2.0 genes in this pathway
SARTIPY NORMAL AT INSULIN RESISTANCE UP 34 27 All SZGR 2.0 genes in this pathway
ABE VEGFA TARGETS 20 15 All SZGR 2.0 genes in this pathway
SAFFORD T LYMPHOCYTE ANERGY 87 54 All SZGR 2.0 genes in this pathway
ABE VEGFA TARGETS 30MIN 29 21 All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 STIMULATED 1022 619 All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 UNSTIMULATED 1229 713 All SZGR 2.0 genes in this pathway
WANG LSD1 TARGETS DN 39 30 All SZGR 2.0 genes in this pathway
HELLER HDAC TARGETS SILENCED BY METHYLATION UP 461 298 All SZGR 2.0 genes in this pathway
MARTINEZ RB1 TARGETS DN 543 317 All SZGR 2.0 genes in this pathway
MARTINEZ TP53 TARGETS DN 593 372 All SZGR 2.0 genes in this pathway
MARTINEZ RB1 AND TP53 TARGETS DN 591 366 All SZGR 2.0 genes in this pathway
RIZKI TUMOR INVASIVENESS 3D UP 210 124 All SZGR 2.0 genes in this pathway
CHENG IMPRINTED BY ESTRADIOL 110 68 All SZGR 2.0 genes in this pathway
RIGGI EWING SARCOMA PROGENITOR UP 430 288 All SZGR 2.0 genes in this pathway
MITSIADES RESPONSE TO APLIDIN UP 439 257 All SZGR 2.0 genes in this pathway
Boquest干细胞培养与新鲜 425 298 All SZGR 2.0 genes in this pathway
LIN NPAS4 TARGETS DN 68 48 All SZGR 2.0 genes in this pathway
Vilimas Notch1靶向 52 41 All SZGR 2.0 genes in this pathway
SEKI INFLAMMATORY RESPONSE LPS UP 77 56 All SZGR 2.0 genes in this pathway
Hunsberger运动调节基因 31 26 All SZGR 2.0 genes in this pathway
Lindstedt树突状细胞成熟D 68 44 All SZGR 2.0 genes in this pathway
李最近的胸腺移民 227 128 All SZGR 2.0 genes in this pathway
CHEN METABOLIC SYNDROM NETWORK 1210 725 All SZGR 2.0 genes in this pathway
Mikkelsen去分化状态DN 7 7 All SZGR 2.0 genes in this pathway
MEISSNER BRAIN HCP WITH H3K4ME3 AND H3K27ME3 1069 729 All SZGR 2.0 genes in this pathway
CHIANG LIVER CANCER SUBCLASS CTNNB1 DN 170 105 All SZGR 2.0 genes in this pathway
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN 37 26 All SZGR 2.0 genes in this pathway
黄成人组织茎模块 721 492 All SZGR 2.0 genes in this pathway
CHANDRAN METASTASIS DN 306 191 All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 30MIN UP 56 38 All SZGR 2.0 genes in this pathway
Bruins通过TP53组A的UVC响应 898 516 All SZGR 2.0 genes in this pathway
MIYAGAWA TARGETS OF EWSR1 ETS FUSIONS UP 259 159 All SZGR 2.0 genes in this pathway
Servitja Islet HNF1A靶向 163 111 All SZGR 2.0 genes in this pathway
PLASARI TGFB1 TARGETS 1HR UP 34 26 All SZGR 2.0 genes in this pathway
PLASARI TGFB1 TARGETS 10HR UP 199 143 All SZGR 2.0 genes in this pathway
phong TNF靶向 63 43 All SZGR 2.0 genes in this pathway
PHONG TNF RESPONSE VIA P38 COMPLETE 227 151 All SZGR 2.0 genes in this pathway
ACEVEDO FGFR1 TARGETS IN PROSTATE CANCER MODEL UP 289 184 All SZGR 2.0 genes in this pathway
LIM MAMMARY STEM CELL UP 489 314 All SZGR 2.0 genes in this pathway
ZWANG CLASS 1 TRANSIENTLY INDUCED BY EGF 516 308 All SZGR 2.0 genes in this pathway
HECKER IFNB1 TARGETS 95 54 All SZGR 2.0 genes in this pathway

第六节。microRNA注释

mirna家族 目标位置 miRNA ID miRNA seq
UTR start UTR end Match method
miR-124.1 907 913 M8 HSA-MIR-124A UUAAGGCACGCGGUGAAUGCCA
miR-124/506 858 864 M8 HSA-MIR-506 UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brain UAAGGCACGCGGUGAAUGCC
HSA-MIR-506 UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brain UAAGGCACGCGGUGAAUGCC
miR-137 579 586 1a,m8 hsa-miR-137 uauugcuuaagaauacgcguag
hsa-miR-137 uauugcuuaagaauacgcguag
miR-141/200a 1029 1035 1a hsa-miR-141 uaacacugucugugugugugaugg
hsa-miR-200a UAACACUGUCUGGUAACGAUGU
mir-142-3p 73 79 M8 hsa-miR-142-3p UGUAGUGUUUCCUACUUUAUGGA
miR-150 401 408 1a,m8 hsa-miR-150 UCUCCCAACCCUUGUACCAGUG
mir-17-5p/20/93.mr/106/519.D 458 465 1a,m8 HSA-MIR-17-5P CAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrain UAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106a AAAAGUGCUUACAGUGCAGGUAGC
hsa - mir - 106 bSZ UAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZ caaagugcuugugcagguag
hsa-miR-519d caaagugccucccuuuagugugu
miR-224 1019 1026 1a,m8 hsa-miR-224 caagucacuaguguguccuuua
mir-25/32/92/363/367 612 618 M8 hsa-miR-25brain CAUUGCACUUGUCUCGGUCUGA
hsa-miR-32 UAUUGCACAUUACUAAGUUGC
hsa-miR-92 uauugcacuugucccgcgcug
hsa-miR-367 Aauugcacuuuagcaaugga
HSA-MIR-92BSZ UAUUGCACUCGUCCCGGCCUC
miR-324-5p 826 832 1a hsa-miR-324-5p CGCAUCCCCUAGGGCAUUGGUGU
miR-34b 962 968 1a hsa-miR-34b UAGGCAGUGUCAUUAGCUGAUUG
miR-377 864 870 M8 hsa-miR-377 aucacacaaaggaacuuuuugu