Gene Page:FABP7

Summary?
GeneID 2173
Symbol FABP7
Synonyms B-FABP|BLBP|FABPB|MRG
Description fatty acid binding protein 7
Reference MIM:602965|HGNC:HGNC:3562|Ensembl:ENSG00000164434|HPRD:04271|Vega:OTTHUMG00000015489
Gene type protein-coding
Map location 6q22-q23
Pascal p-value 0.004
Sherlock p-value 0.011
Fetal beta 2.197

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
PMID:cooccur High-throughput literature-search Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
Association A combined odds ratio method (Sun et al. 2008), association studies 1 Link to SZGene
Literature High-throughput literature-search Co-occurance与Schizophrenia keywords: schizophrenia,schizophrenic,schizophrenias Click to show details
GO_Annotation Mapping neuro-related keywords to Gene Ontology annotations Hits with neuro-related keywords: 3

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
KHDRBS1 0.94 0.95
HNRNPL 0.94 0.91
POLDIP3 0.94 0.93
SF3B3 0.94 0.93
HNRNPA0 0.93 0.94
WDR40A 0.93 0.95
SMAD4 0.93 0.92
ACTG1 0.93 0.91
GLE1 0.93 0.94
BUB3 0.93 0.93
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
MT-CO2 -0.72 -0.90
HLA-F -0.72 -0.80
AF347015.31 -0.72 -0.88
AF347015.27 -0.72 -0.88
AF347015.33 -0.72 -0.89
C5orf53 -0.72 -0.77
FXYD1 -0.71 -0.89
MT-CYB -0.70 -0.88
S100B -0.70 -0.84
AF347015.8 -0.70 -0.90

Section III. Gene Ontology annotation

Molecular function GO term Evidence Neuro keywords PubMed ID
GO:0005215 transporter activity IEA -
GO:0008289 lipid binding IEA -
GO:0008289 lipid binding TAS 9375786
Biological process GO term Evidence Neuro keywords PubMed ID
GO:0007399 nervous system development TAS neurite (GO term level: 5) 9375786
GO:0008285 negative regulation of cell proliferation TAS 9250612
GO:0006810 transport IEA -
Cellular component GO term Evidence Neuro keywords PubMed ID
GO:0043025 cell soma IEA axon, dendrite (GO term level: 4) -
GO:0042995 cell projection IEA axon (GO term level: 4) -
GO:0005737 cytoplasm IEA -

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
KEGG PPAR SIGNALING PATHWAY 69 47 All SZGR 2.0 genes in this pathway
SENGUPTA NASOPHARYNGEAL CARCINOMA WITH LMP1 UP 408 247 All SZGR 2.0 genes in this pathway
DOANE BREAST CANCER ESR1 DN 48 28 All SZGR 2.0 genes in this pathway
LEE NEURAL CREST STEM CELL DN 118 79 All SZGR 2.0 genes in this pathway
MARKEY RB1 CHRONIC LOF DN 118 78 All SZGR 2.0 genes in this pathway
KAN RESPONSE TO ARSENIC TRIOXIDE 123 80 All SZGR 2.0 genes in this pathway
FARMER BREAST CANCER APOCRINE VS LUMINAL 326 213 All SZGR 2.0 genes in this pathway
MARTORIATI MDM4 TARGETS NEUROEPITHELIUM DN 164 111 All SZGR 2.0 genes in this pathway
MARTORIATI MDM4 TARGETS FETAL LIVER UP 227 137 All SZGR 2.0 genes in this pathway
SHEN SMARCA2 TARGETS DN 357 212 All SZGR 2.0 genes in this pathway
UEDA CENTRAL CLOCK 88 62 All SZGR 2.0 genes in this pathway
SHEPARD BMYB MORPHOLINO DN 200 112 All SZGR 2.0 genes in this pathway
SANSOM APC TARGETS DN 366 238 All SZGR 2.0 genes in this pathway
URS ADIPOCYTE DIFFERENTIATION UP 74 51 All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE DN 1237 837 All SZGR 2.0 genes in this pathway
LIAN LIPA TARGETS 6M 74 47 All SZGR 2.0 genes in this pathway
MODY HIPPOCAMPUS NEONATAL 35 25 All SZGR 2.0 genes in this pathway
LEE AGING CEREBELLUM DN 86 66 All SZGR 2.0 genes in this pathway
KIM GASTRIC CANCER CHEMOSENSITIVITY 103 64 All SZGR 2.0 genes in this pathway
LIAN LIPA TARGETS 3M 59 36 All SZGR 2.0 genes in this pathway
MCCLUNG CREB1 TARGETS UP 100 72 All SZGR 2.0 genes in this pathway
FOSTER TOLERANT MACROPHAGE UP 156 92 All SZGR 2.0 genes in this pathway
SMID BREAST CANCER RELAPSE IN BONE DN 315 197 All SZGR 2.0 genes in this pathway
SMID BREAST CANCER RELAPSE IN PLEURA DN 27 15 All SZGR 2.0 genes in this pathway
乳腺癌萧述三腔的DN 564 326 All SZGR 2.0 genes in this pathway
SMID BREAST CANCER BASAL UP 648 398 All SZGR 2.0 genes in this pathway
GRADE COLON AND RECTAL CANCER DN 101 65 All SZGR 2.0 genes in this pathway
VANTVEER BREAST CANCER ESR1 DN 240 153 All SZGR 2.0 genes in this pathway
COLINA TARGETS OF 4EBP1 AND 4EBP2 356 214 All SZGR 2.0 genes in this pathway
CHEN METABOLIC SYNDROM NETWORK 1210 725 All SZGR 2.0 genes in this pathway
POOLA INVASIVE BREAST CANCER DN 134 83 All SZGR 2.0 genes in this pathway
MIKKELSEN MCV6 LCP WITH H3K4ME3 162 80 All SZGR 2.0 genes in this pathway
MIKKELSEN NPC LCP WITH H3K4ME3 58 34 All SZGR 2.0 genes in this pathway
KIM BIPOLAR DISORDER OLIGODENDROCYTE DENSITY CORR UP 682 440 All SZGR 2.0 genes in this pathway
VANDESLUIS COMMD1 TARGETS GROUP 4 DN 16 11 All SZGR 2.0 genes in this pathway
SERVITJA ISLET HNF1A TARGETS UP 163 111 All SZGR 2.0 genes in this pathway
WANG MLL TARGETS 289 188 All SZGR 2.0 genes in this pathway
DURAND STROMA S UP 297 194 All SZGR 2.0 genes in this pathway