Gene Page:FANCF

Summary?
GeneID 2188
Symbol FANCF
Synonyms FAF
Description Fanconi anemia complementation group F
Reference MIM:613897|HGNC:HGNC:3587|HPRD:04589|
Gene type protein-coding
Map location 11p15
Pascal p-value 0.104
Fetal beta 0.995
DMG 1 (# studies)

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
DMG:Jaffe_2016 Genome-wide DNA methylation analysis This dataset includes 2,104 probes/CpGs associated with SZ patients (n=108) compared to 136 controls at Bonferroni-adjusted P < 0.05. 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

Probe Chromosome Position Nearest gene P (dis) Beta (dis) FDR (dis) Study
cg08585315 11 22647410 FANCF 1.56E-8 -0.013 5.84E-6 DMG:Jaffe_2016


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
TFPT 0.72 0.61
ARHGDIG 0.72 0.72
TMEM205 0.72 0.70
SELM 0.71 0.66
TMEM42 0.71 0.66
FDX1L 0.70 0.64
GUK1 0.70 0.67
TMEM141 0.70 0.69
CCDC85B 0.69 0.71
PRSS3 0.68 0.75
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
THOC2 -0.47 -0.61
KIAA1949 -0.47 -0.59
SH3BP2 -0.47 -0.65
ZNF551 -0.46 -0.55
AC004017.1 -0.46 -0.55
SETDB1 -0.46 -0.50
TUBB2B -0.45 -0.62
ZNF300 -0.45 -0.52
NASP -0.45 -0.62
ZNF326 -0.45 -0.56

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
BIOCARTA ATRBRCA PATHWAY 21 12 All SZGR 2.0 genes in this pathway
PID FANCONI PATHWAY 47 28 All SZGR 2.0 genes in this pathway
PID BARD1 PATHWAY 29 19 All SZGR 2.0 genes in this pathway
REACTOME FANCONI ANEMIA PATHWAY 25 11 All SZGR 2.0 genes in this pathway
REACTOME DNA REPAIR 112 59 All SZGR 2.0 genes in this pathway
HOLLMANN APOPTOSIS VIA CD40 DN 267 178 All SZGR 2.0 genes in this pathway
DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP 1382 904 All SZGR 2.0 genes in this pathway
CHARAFE BREAST CANCER LUMINAL VS MESENCHYMAL UP 450 256 All SZGR 2.0 genes in this pathway
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS BLUE DN 61 35 All SZGR 2.0 genes in this pathway
MATHEW FANCONI ANEMIA GENES 11 7 All SZGR 2.0 genes in this pathway
ROVERSI GLIOMA LOH REGIONS 44 30 All SZGR 2.0 genes in this pathway
OHM METHYLATED IN ADULT CANCERS 27 23 All SZGR 2.0 genes in this pathway
BUYTAERT PHOTODYNAMIC THERAPY STRESS DN 637 377 All SZGR 2.0 genes in this pathway
BENPORATH NANOG TARGETS 988 594 All SZGR 2.0 genes in this pathway
BENPORATH SOX2 TARGETS 734 436 All SZGR 2.0 genes in this pathway
BENPORATH MYC MAX TARGETS 775 494 All SZGR 2.0 genes in this pathway
考夫曼DNA再保险PAIR GENES 230 137 All SZGR 2.0 genes in this pathway
MOREAUX MULTIPLE MYELOMA BY TACI DN 172 107 All SZGR 2.0 genes in this pathway
STEIN ESRRA TARGETS UP 388 234 All SZGR 2.0 genes in this pathway
CHENG IMPRINTED BY ESTRADIOL 110 68 All SZGR 2.0 genes in this pathway
霍克甲基化在癌症 56 45 All SZGR 2.0 genes in this pathway
BHATI G2M ARREST BY 2METHOXYESTRADIOL DN 127 75 All SZGR 2.0 genes in this pathway
CADWELL ATG16L1 TARGETS DN 70 43 All SZGR 2.0 genes in this pathway
GRESHOCK CANCER COPY NUMBER UP 323 240 All SZGR 2.0 genes in this pathway
STEIN ESRRA TARGETS 535 325 All SZGR 2.0 genes in this pathway
DANG BOUND BY MYC 1103 714 All SZGR 2.0 genes in this pathway