Summary
GeneID 22800
Symbol RRAS2
同义词 TC21
描述 related RAS viral (r-ras) oncogene homolog 2
参考 MIM:600098|HGNC:HGNC:17271|ENSEMBL:ENSG00000133818|HPRD:02518|Vega:Otthumg00000165756
基因类型 蛋白质编码
地图位置 11P15.2
Pascal P值 0.02
胎儿β 1.233
DMG 1(# studies)

Gene in Data Sources
基因集名称 基因组方法 描述 信息
简历:PGCNP 全基因组协会研究 GWAS
DMG:Wockner_2014 全基因组DNA甲基化分析 该数据集包括4641个差异甲基化探针,对应于精神分裂症患者(n = 24)和对照组(n = 24)之间的2929个独特基因。 1

Section I. Genetics and epigenetics annotation

@差异甲基化基因

探测 染色体 位置 最近的基因 p(dis) beta(dis) fdr(dis) 学习
CG16148674 11 14380065 RRAS2 4.464e-4 -0.223 0.045 DMG:Wockner_2014


第二节。转录组注释

一般基因表达(GTEX)

无法使用

Devlopment期间的基因表达(BrainCloud)

Footnote:
总共绘制了269个时间点,n = 38个胎儿样品(x = 1:38)。每个三角形代表一个时间点。

时间变化的基因表达(brainspan)

Footnote:
SC:亚皮质区域;SM:感觉运动区域;FC:额叶皮层;和TP:颞顶皮层
ST1:胎儿(13-26个概念后周),ST2:婴儿早期至童年(4个月至11年)和ST3:青春期至成年期(13-23年)
所示的栏表示表达分布的较低25%和上层25%。

大脑区域没有共表达基因


Section IV. Protein-protein interaction annotation

Interactors 别名b 官方全名b 实验 Source PubMed ID
AHSG A2HS |ahs |fetua |HSGA alpha-2-HS-glycoprotein 体外 Biogrid 11788587
阿拉夫 A-RAF | ARAF1 | PKS2 | RAFA1 V-RAF鼠肉瘤3611病毒癌基因同源物 A-RAF与R-RAS相互作用。 绑定 12620389
阿拉夫 A-RAF | ARAF1 | PKS2 | RAFA1 V-RAF鼠肉瘤3611病毒癌基因同源物 A-RAF与R-RAS相互作用。 绑定 12620389
Arhgef2 DKFZP547L106 |DKFZP547P1516 |GEF |GEF-H1 |gefh1 |KIAA0651 |LFP40 |P40 rho/rac guanine nucleotide exchange factor (GEF) 2 - HPRD 12384139
LGALS4 gal4 |L36LBP lectin, galactoside-binding, soluble, 4 Two-hybrid Biogrid 16169070
MLLT4 AF-6 |AF6 |Afadin |FLJ34371 |RP3-431P23.3 髓样/淋巴样或混合细胞白血病(果蝇Trithorax同源物);易位为4 - HPRD,Biogrid 10224125|11788587
PIK3R1 grb1 |P85 |p85-alpha 磷酸肌醇3-激酶,调节亚基1(alpha) - HPRD,Biogrid 11850823
PTPN1 ptp1b 蛋白质酪氨酸磷酸酶,非受体1型 - HPRD,Biogrid 11788587
Rabac1 pra1 |praf1 |yip3 RAB受体1(原始化) - HPRD 11335720
RAF1 克拉夫|NS5 |RAF-1 |C-Raf V-RAF-1鼠白血病病毒癌基因同源1 RAF1(C-RAF)与RRAS2(R-RAS)相互作用。 绑定 12620389
RAF1 克拉夫|NS5 |RAF-1 |C-Raf V-RAF-1鼠白血病病毒癌基因同源1 重构的复合物
Two-hybrid
Biogrid 10557073|10783161
RAF1 克拉夫|NS5 |RAF-1 |C-Raf V-RAF-1鼠白血病病毒癌基因同源1 - HPRD 10064593
ralgds FLJ20922 |RGF |拉尔奇夫 ral guanine nucleotide dissociation stimulator - HPRD,Biogrid 11788587
Rapgef1 C3G | DKFZp781P1719 | GRF2 说唱鸟嘌呤核苷酸交换因子(GEF) 1 - HPRD 12384139
Rapgef3 CAMP-GEFI | EPAC | EPAC1 | HSU79275 | MGC21410 | bcm910 Rap guanine nucleotide exchange factor (GEF) 3 - HPRD 12384139
Rapgef4 营地|CGEF2 |epac2 |NBLA00496 Rap guanine nucleotide exchange factor (GEF) 4 - HPRD 12384139
RASIP1 FLJ20401 |雨 Ras interacting protein 1 - HPRD 15031288
RASSF5 MGC10823 |MGC17344 |maxp1 |nore1 |nore1a |nore1b |Rapl |RASSF3 RAS协会(RALGDS/AF-6)域家庭成员5 - HPRD 11857081
RIN1 - Ras和Rab Interactor 1 - HPRD,Biogrid 11788587
TRAF3 CAP-1 |CD40BP |craf1 |LAP1 TNF受体相关因子3 - HPRD 10557073
XRCC6 CTC75 |CTCBF |G22P1 |ku70 |ML8 |TLAA X射线修复补充中国仓鼠细胞中有缺陷的修复6 Two-hybrid Biogrid 16169070


Section V. Pathway annotation

路径名 路径大小 #szgr 2.0基因 信息
kegg mapk信号通路 267 205 All SZGR 2.0 genes in this pathway
kegg thright连接点 134 86 All SZGR 2.0 genes in this pathway
KEGG REGULATION OF ACTIN CYTOSKELETON 216 144 All SZGR 2.0 genes in this pathway
GAZDA DIAMOND BLACKFAN ANEMIA PROGENITOR UP 39 25 All SZGR 2.0 genes in this pathway
Puiffe入侵被腹水DN抑制 145 91 All SZGR 2.0 genes in this pathway
HUTTMANN B CLL POOR SURVIVAL DN 60 39 All SZGR 2.0 genes in this pathway
迪亚兹慢性巨态性白血病 1382 904 All SZGR 2.0 genes in this pathway
乳腺癌腔与基础DN 455 304 All SZGR 2.0 genes in this pathway
胶原蛋白凝胶DN中的Oswald造血干细胞 275 168 All SZGR 2.0 genes in this pathway
Dittmer PTHLH靶向DN 73 51 All SZGR 2.0 genes in this pathway
Kim WT1靶向 214 155 All SZGR 2.0 genes in this pathway
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP 57 33 All SZGR 2.0 genes in this pathway
甲状腺癌的甲状腺癌间变性 722 443 All SZGR 2.0 genes in this pathway
ENK UV响应表皮增强 293 179 All SZGR 2.0 genes in this pathway
Dacosta UV响应通过ERCC3 DN 855 609 All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 COMMON DN 483 336 All SZGR 2.0 genes in this pathway
GROSS ELK3靶向 27 16 All SZGR 2.0 genes in this pathway
通过ELK3 UP总缺氧 209 139 All SZGR 2.0 genes in this pathway
Nuytten EZH2靶向 1037 673 All SZGR 2.0 genes in this pathway
buytaert光动力疗法压力 811 508 All SZGR 2.0 genes in this pathway
LOPEZ MBD TARGETS 957 597 All SZGR 2.0 genes in this pathway
RICKMAN TUMOR DIFFERENTIATED WELL VS MODERATELY DN 110 64 All SZGR 2.0 genes in this pathway
Schaeffer前列腺开发48小时 487 286 All SZGR 2.0 genes in this pathway
Benporath ES 1 379 235 All SZGR 2.0 genes in this pathway
阿斯顿主要抑郁症 49 36 All SZGR 2.0 genes in this pathway
弗莱赫纳活检肾脏移植被拒绝vs ok dn 546 351 All SZGR 2.0 genes in this pathway
Haslinger B Cll具有17p13删除 21 15 All SZGR 2.0 genes in this pathway
肥胖症的纳德勒高血糖 58 35 All SZGR 2.0 genes in this pathway
flt3的大风apl突变 56 35 All SZGR 2.0 genes in this pathway
YAGI AML FAB MARKERS 191 131 All SZGR 2.0 genes in this pathway
葡萄病毒感染的Debiasi凋亡 314 201 All SZGR 2.0 genes in this pathway
Wang Smarce1靶向DN 371 218 All SZGR 2.0 genes in this pathway
CUI TCF21目标2 DN 830 547 All SZGR 2.0 genes in this pathway
Browne HCMV感染24小时DN 148 102 All SZGR 2.0 genes in this pathway
Browne HCMV感染14小时DN 298 200 All SZGR 2.0 genes in this pathway
Browne HCMV感染20小时DN 101 70 All SZGR 2.0 genes in this pathway
Browne HCMV感染48小时DN 504 323 All SZGR 2.0 genes in this pathway
CHEN LVAD SUPPORT OF FAILING HEART UP 103 69 All SZGR 2.0 genes in this pathway
外邦紫外线响应集群D7 40 21 All SZGR 2.0 genes in this pathway
外邦紫外线高剂量DN 312 203 All SZGR 2.0 genes in this pathway
ZHANG ANTIVIRAL RESPONSE TO RIBAVIRIN DN 51 32 All SZGR 2.0 genes in this pathway
dazard对UV SCC的反应 123 75 All SZGR 2.0 genes in this pathway
Burton脂肪形成峰在8小时 39 31 All SZGR 2.0 genes in this pathway
Zheng由Foxp3绑定 491 310 All SZGR 2.0 genes in this pathway
ZHENG FOXP3 TARGETS IN T LYMPHOCYTE UP 12 7 All SZGR 2.0 genes in this pathway
我看TES MACROPHAGE M1 VS M2 DN 78 44 All SZGR 2.0 genes in this pathway
Marzec IL2发出信号 115 80 All SZGR 2.0 genes in this pathway
Rizki肿瘤侵入性3D DN 270 181 All SZGR 2.0 genes in this pathway
SMID乳腺癌腔B DN 564 326 All SZGR 2.0 genes in this pathway
Smid乳腺癌基础 648 398 All SZGR 2.0 genes in this pathway
Qi Plasmacytoma Up 259 185 All SZGR 2.0 genes in this pathway
王肿瘤的侵入性 374 247 All SZGR 2.0 genes in this pathway
BOYLAN MULTIPLE MYELOMA C CLUSTER DN 32 21 All SZGR 2.0 genes in this pathway
Boylan多发性骨髓瘤C D DN 252 155 All SZGR 2.0 genes in this pathway
Vilimas Notch1靶向 52 41 All SZGR 2.0 genes in this pathway
p210 bcr abl融合的射线目标 18 13 All SZGR 2.0 genes in this pathway
Ruiz TNC靶向DN 142 79 All SZGR 2.0 genes in this pathway
Lee胸前T祖细胞 21 14 All SZGR 2.0 genes in this pathway
Meissner Brain HCP带有H3K4ME3和H3K27ME3 1069 729 All SZGR 2.0 genes in this pathway
Boyault肝癌子类G2 27 17 All SZGR 2.0 genes in this pathway
Chicas RB1目标汇合 567 365 All SZGR 2.0 genes in this pathway
Pilon KLF1靶向DN 1972年 1213 All SZGR 2.0 genes in this pathway
Johnstone Parvb目标3 430 288 All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE VIA TP53 GROUP B 549 316 All SZGR 2.0 genes in this pathway
棕熊UVC响应很晚 317 190 All SZGR 2.0 genes in this pathway
pasini suz12靶向DN 315 215 All SZGR 2.0 genes in this pathway
Lee BMP2靶向DN 882 538 All SZGR 2.0 genes in this pathway
Krieg缺氧不是通过KDM3A 770 480 All SZGR 2.0 genes in this pathway