Gene Page:VASH1

Summary?
GeneID 22846
Symbol VASH1
Synonyms KIAA1036
Description vasohibin 1
Reference MIM:609011|HGNC:HGNC:19964|Ensembl:ENSG00000071246|HPRD:12353|Vega:OTTHUMG00000171493
Gene type protein-coding
Map location 14q24.3
Pascal p-value 0.547
Sherlock p-value 0.281
Fetal beta 1.863
DMG 1 (# studies)
eGene Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
DMG:Wockner_2014 Genome-wide DNA methylation analysis This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

Probe Chromosome Position Nearest gene P (dis) Beta (dis) FDR (dis) Study
cg21074797 14 77244003 VASH1 5.1E-4 0.291 0.047 DMG:Wockner_2014

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs2268637 chr6 39050917 VASH1 22846 0.04 trans
rs8003795 chr14 37092584 VASH1 22846 0.19 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception周),ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
GIGYF2 0.95 0.95
PHF3 0.93 0.93
EIF3A 0.93 0.94
YLPM1 0.92 0.91
RSF1 0.92 0.93
BAZ1B 0.92 0.93
TAF1 0.91 0.93
TPR 0.91 0.92
PCM1 0.91 0.91
SLTM 0.91 0.93
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
ENHO -0.71 -0.82
IFI27 -0.71 -0.79
AF347015.31 -0.68 -0.76
MT3 -0.68 -0.79
HIGD1B -0.67 -0.78
B2M -0.67 -0.69
METRN -0.67 -0.77
RAMP1 -0.67 -0.74
MYL3 -0.67 -0.75
FXYD1 -0.66 -0.74

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
HOOI ST7 TARGETS DN 123 78 All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 6HR DN 41 29 All SZGR 2.0 genes in this pathway
BENPORATH SUZ12 TARGETS 1038 678 All SZGR 2.0 genes in this pathway
BENPORATH EED TARGETS 1062 725 All SZGR 2.0 genes in this pathway
BENPORATH ES WITH H3K27ME3 1118 744 All SZGR 2.0 genes in this pathway
BENPORATH PRC2 TARGETS 652 441 All SZGR 2.0 genes in this pathway
SU PANCREAS 54 30 All SZGR 2.0 genes in this pathway
KAAB HEART ATRIUM VS VENTRICLE UP 249 170 All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 48HR DN 504 323 All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 18HR DN 178 121 All SZGR 2.0 genes in this pathway
RODWELL AGING KIDNEY UP 487 303 All SZGR 2.0 genes in this pathway
SMID BREAST CANCER NORMAL LIKE UP 476 285 All SZGR 2.0 genes in this pathway
CHANG CORE SERUM RESPONSE DN 209 137 All SZGR 2.0 genes in this pathway
ROME INSULIN TARGETS IN MUSCLE DN 204 114 All SZGR 2.0 genes in this pathway
YAGI AML WITH 11Q23 REARRANGED 351 238 All SZGR 2.0 genes in this pathway
GUTIERREZ CHRONIC LYMPHOCYTIC LEUKEMIA DN 56 39 All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 1HR DN 222 147 All SZGR 2.0 genes in this pathway
LI INDUCED T TO NATURAL KILLER UP 307 182 All SZGR 2.0 genes in this pathway
CHICAS RB1 TARGETS SENESCENT 572 352 All SZGR 2.0 genes in this pathway
WIERENGA STAT5A TARGETS DN 213 127 All SZGR 2.0 genes in this pathway
FORTSCHEGGER PHF8 TARGETS DN 784 464 All SZGR 2.0 genes in this pathway