Gene Page:FNDC3A

Summary？
基因 22862
象征 FNDC3A
Synonyms FNDC3 | Hugo | BA203I16.1 | BA203I16.5
Description 纤连蛋白III型含有3A
Reference MIM：615794|HGNC：HGNC：20296|Ensembl:ENSG00000102531|HPRD:13548|Vega：Otthumg0000000016911
基因类型 蛋白质编码
Map location 13q14.2
Pascal p-value 0.102
Sherlock p-value 0.664
胎儿β 0.164
DMG 1(# studies)
主持人 Myers' cis & trans

Gene in Data Sources
基因集名称 Method of gene set Description 信息
CV:PGCnp 全基因组关联研究 GWAS
DMG：Vaneijk_2014 全基因组DNA甲基化分析 该数据集包括432个差异甲基化的CpG位点，对应于精神分裂症患者（n = 260）和未受影响的对照（n = 250）之间的391个独特的转录本。 1

Section I. Genetics and epigenetics annotation

@差异甲基化基因

Probe 染色体 位置 最近的基因 p（dis） Beta (dis) fdr（dis） 学习
cg02321871 13 50159138 FNDC3A 0.002 -3.287 DMG：Vaneijk_2014

@EQTL注释

SNP ID 染色体 位置 主持人 Gene Entrez ID pvalue QVALUE TSS距离 EQTL类型
RS7629431 CHR3 189336841 FNDC3A 22862 0.2 反式
RS4491879 CHR3 189373908 FNDC3A 22862 0.01 反式
rs4505678 CHR3 189374356 FNDC3A 22862 0.02 反式

第二节。转录组注释

一般基因表达（GTEX）

Not available

Devlopment期间的基因表达（BrainCloud）

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

时间变化的基因表达（brainspan）

Footnote:
SC：亚皮质区域；SM：感觉运动区域；FC：额叶皮层；和TP：颞顶皮层
ST1：胎儿（13-26个概念后周），ST2：婴儿早期至童年（4个月至11年）和ST3：青春期至成年期（13-23年）
所示的栏表示表达分布的较低25％和上层25％。

大脑区域的顶级共表达基因

前10个积极共表达的基因
Gene Pearson's Correlation 斯皮尔曼的相关性
atxn10 0.92 0.91
ARMC8 0.92 0.91
npepps 0.91 0.90
ASB8 0.91 0.91
ATF2 0.91 0.92
sar1a 0.91 0.91
AC087742.2 0.91 0.90
BNIP3L 0.91 0.92
SMAD2 0.90 0.91
FAF1 0.90 0.92
Top 10 negatively co-expressed genes
Gene Pearson's Correlation 斯皮尔曼的相关性
MT-CO2 -0.84 -0.85
AF347015.8 -0.83 -0.85
AF347015.31 -0.82 -0.82
mt-cyb -0.82 -0.83
AF347015.27 -0.81 -0.83
AF347015.21 -0.80 -0.82
AF347015.15 -0.80 -0.83
AF347015.33 -0.80 -0.81
AF347015.2 -0.79 -0.81
AF347015.26 -0.78 -0.82

第三节。基因本体论注释

生物过程 去学期 证据 神经关键字 PubMed ID
GO:0007286 精子发育 IEA -
去：0009566 受精 IEA -
GO：0016337 细胞细胞粘附 IEA -
Cellular component 去学期 证据 神经关键字 PubMed ID
GO:0001669 ACROSOME IEA -
GO:0012506 vesicle membrane IEA -
GO:0005829 细胞质 IEA -
去：0005783 内质网 艾达 18029348
GO:0042598 vesicular fraction IEA -
GO：0031410 细胞质囊泡 IEA -

Section V. Pathway annotation

路径名 路径大小 # SZGR 2.0 genes in pathway 信息
中村肿瘤区周围与中央DN 634 384 All SZGR 2.0 genes in this pathway
Chemnitz对前列腺素E2 DN的反应 391 222 All SZGR 2.0 genes in this pathway
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS UP 579 346 All SZGR 2.0 genes in this pathway
Tien肠益生菌24小时DN 214 133 All SZGR 2.0 genes in this pathway
Castellano NRAS靶向 68 41 All SZGR 2.0 genes in this pathway
Markey RB1急性lof 215 137 All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY SERUM DEPRIVATION UP 552 347 All SZGR 2.0 genes in this pathway
Gaussmann MLL AF4融合靶标C向上 170 114 All SZGR 2.0 genes in this pathway
TAKADA GASTRIC CANCER COPY NUMBER DN 29 15 All SZGR 2.0 genes in this pathway
Dacosta UV响应通过ERCC3 DN 855 609 All SZGR 2.0 genes in this pathway
Dacosta UV响应通过ERCC3公共DN 483 336 All SZGR 2.0 genes in this pathway
洛佩兹MBD目标 957 597 All SZGR 2.0 genes in this pathway
Wotton Runx目标DN 29 18 All SZGR 2.0 genes in this pathway
PASQUALUCCI LYMPHOMA BY GC STAGE UP 283 177 All SZGR 2.0 genes in this pathway
STARK PREFRONTAL CORTEX 22Q11 DELETION UP 195 138 All SZGR 2.0 genes in this pathway
TCGA GLIOBLASTOMA COPY NUMBER DN 31 21 All SZGR 2.0 genes in this pathway
弗莱赫纳活检肾脏移植被拒绝vs ok dn 546 351 All SZGR 2.0 genes in this pathway
Flechner活检肾脏移植OK vs捐助者 555 346 All SZGR 2.0 genes in this pathway
NGUYEN NOTCH1 TARGETS DN 86 67 All SZGR 2.0 genes in this pathway
CUI TCF21 TARGETS 2 DN 830 547 All SZGR 2.0 genes in this pathway
Yamazaki TCEB3靶向 175 116 All SZGR 2.0 genes in this pathway
Dazard对UV NHEK DN的反应 318 220 All SZGR 2.0 genes in this pathway
DAZARD UV RESPONSE CLUSTER G6 153 112 All SZGR 2.0 genes in this pathway
马丁内斯对trabectedin dn的反应 271 175 All SZGR 2.0 genes in this pathway
FOSTER TOLERANT MACROPHAGE DN 409 268 All SZGR 2.0 genes in this pathway
HELLER HDAC TARGETS SILENCED BY METHYLATION DN 281 179 All SZGR 2.0 genes in this pathway
林黑色素瘤副本编号DN 41 34 All SZGR 2.0 genes in this pathway
Bonome卵巢癌的生存次优秀 510 309 All SZGR 2.0 genes in this pathway
张乳腺癌祖细胞DN 145 93 All SZGR 2.0 genes in this pathway
ehlers neuploidy up 41 29 All SZGR 2.0 genes in this pathway
Matzuk精子分化 37 26 All SZGR 2.0 genes in this pathway
MATZUK SPERMATOZOA 114 77 All SZGR 2.0 genes in this pathway
podar对Apaphostin的反应 147 98 All SZGR 2.0 genes in this pathway
米利假足 518 299 All SZGR 2.0 genes in this pathway
ikeda mir1靶向 53 39 All SZGR 2.0 genes in this pathway
ikeda mir30目标 116 87 All SZGR 2.0 genes in this pathway
Wang MLL目标 289 188 All SZGR 2.0 genes in this pathway
天bhlha15目标 16 8 All SZGR 2.0 genes in this pathway
Zwang 3类由EGF瞬时诱导 222 159 All SZGR 2.0 genes in this pathway

第六节。microRNA注释

mirna家族 Target position miRNA ID mirna seq
UTR开始 UTR结束 匹配方法
Let-7/98 465 471 M8 hsa-let-7abrain ugagguaguaguauauaguu
hsa-let-7bbrain ugagguaguagguuguguguguu
hsa-let-7cbrain UGAGGUAGUAGGUUGUAUGGUU
hsa-let-7dbrain AGAGGUAGUAGGUUGCAUAGU
hsa-let-7ebrain ugagguaggagguuauauagu
hsa-let-7fbrain UGAGGUAGUAGAUUGUAUAGUU
HSA-MIR-98brain ugagguaaguuguauuguu
hsa-let-7gSZ ugagguaguuguuguacagu
hsa-let-7ibrain ugagguaguugugugugugcugu
hsa-let-7abrain ugagguaguaguauauaguu
hsa-let-7bbrain ugagguaguagguuguguguguu
hsa-let-7cbrain UGAGGUAGUAGGUUGUAUGGUU
hsa-let-7dbrain AGAGGUAGUAGGUUGCAUAGU
hsa-let-7ebrain ugagguaggagguuauauagu
hsa-let-7fbrain UGAGGUAGUAGAUUGUAUAGUU
HSA-MIR-98brain ugagguaaguuguauuguu
hsa-let-7gSZ ugagguaguuguuguacagu
hsa-let-7ibrain ugagguaguugugugugugcugu
mir-1/206 2017 2024 1A，M8 hsa-miR-1 UGGAAUGUAAAGAAGUAUGUA
hsa-miR-206SZ Uggaauguaaggaagugugugg
hsa - mir - 613 AGGAAUGUUCCUUCUUUGCC
mir-101 2011 2017 1a hsa-miR-101 uacaguacugauaacugaag
mir-129-5p 1594年 1600 1a HSA-MIR-129brain cuuuuugcgguggggcuugc
HSA-MIR-129-5p cuuuuugcgguggggcuugcu
miR-137 444 450 M8 HSA-MIR-137 uauugcuuaagaauacgcguag
miR-142-3p 2055 2061 M8 HSA-MIR-142-3P UGUAGUGUUUCCUACUUUAUGGA
miR-142-5p 8 14 M8 HSA-MIR-142-5P cauaaaguagaaagcacuac
miR-144 2010年 2017 1A，M8 HSA-MIR-144 UACAGUAUAGAUGAUGUACUAG
HSA-MIR-144 UACAGUAUAGAUGAUGUACUAG
miR-145 514 520 M8 HSA-MIR-145 guccaguuucccaggaaucccuu
HSA-MIR-145 guccaguuucccaggaaucccuu
miR-17-5p/20/93.mr/106/519.d 1167 1173 M8 HSA-MIR-17-5P caaagugcuuacugcagguagu
hsa-miR-20abrain UAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106a AAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZ UAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZ caaagugcuugugcagguag
HSA-MIR-519D caaagugccucccuuuagugugu
miR-181 1820 1826 M8 HSA-MIR-181Abrain AACAUUCAACGCUGUCGGUGAGU
HSA-MIR-181BSZ aacauucauugcugucggggg
HSA-MIR-181Cbrain AACAUUCAACCUGUCGGUGAGU
HSA-MIR-181Dbrain aacauucauuguugucggggguggguu
miR-186 2188 2194 M8 HSA-MIR-186 caaagaauuuugggcuu
miR-19 1051 1057 M8 HSA-MIR-19A ugugcaaauaugauaugaaaacuga
HSA-MIR-19B UGUGCAAAUCCAUGCAAAACUGA
mir-208 479 485 1a hsa-miR-208 auaagacgaaaaaagcuugu
mir-221/222 2141 2148 1A，M8 hsa-miR-221brain agcuacauugucugugggggguc
hsa-miR-222brain agcuacaucuggcuacugggucuc
miR-27 438 444 1a HSA-MIR-27Abrain uucacaguggcuaaguuccgc
HSA-MIR-27Bbrain uucacaguggcuaaguucugc
mir-30-5p 1662 1669 1A，M8 HSA-MIR-30A-5P uguaaaacauccuccugagaag
hsa-miR-30cbrain UGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZ UGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZ uguaaacauccuaccucucagcu
hsa-miR-30e-5p UGUAAACAUCCUUGACUGGA
miR-31 1934 1940 1a hsa-miR-31 Aggcaagaugcuggcauagcug
mir-326 1800 1807年 1A，M8 hsa-miR-326 CCUCUGGGCCCUUCCUCCAG
mir-376c 2139 2145 1a HSA-MIR-376C aacauagaggaaauuccacg
miR-381 2081 2087 1a HSA-MIR-381 uauacaagggcaagcucucugu
miR-499 479 485 1a HSA-MIR-499 UUAAGACUUGCAGUGAUGUUUAA
miR-542-3p 1641 1647 M8 hsa-miR-542-3p UGUGACAGAUUGAUAACUGAAA
miR-93.hd/291-3p/294/295/302/372/373/520 1450 1456 M8 HSA-MIR-93brain aaagugcuguucgugcagguag
hsa-miR-302a uaagugcuugcauguuuguga
hsa-miR-302b UAAGUGCUUCCAUGUUUUAGUAG
hsa-miR-302c uaagugcuuccauguucagugg
hsa-miR-302d Uaagugcuauguugugugu
HSA-MIR-372 AAAGUGCUGCGACAUUUGAGCGU
HSA-MIR-373 Gaagugcuucgauuuggggugu
HSA-MIR-520E Aaagugcuuuuuugaggg
hsa-miR-520a AAAGUGCUUCCCUUUGGACUGU
hsa-miR-520b aaagugcuuuuuuagaggg
hsa-miR-520c aaagugcuuuuuuaggggug
hsa-miR-520d aaaguguuugugggguggguu
HSA-MIR-93brain aaagugcuguucgugcagguag
hsa-miR-302a uaagugcuugcauguuuguga
hsa-miR-302b UAAGUGCUUCCAUGUUUUAGUAG
hsa-miR-302c uaagugcuuccauguucagugg
hsa-miR-302d Uaagugcuauguugugugu
HSA-MIR-372 AAAGUGCUGCGACAUUUGAGCGU
HSA-MIR-373 Gaagugcuucgauuuggggugu
HSA-MIR-520E Aaagugcuuuuuugaggg
hsa-miR-520a AAAGUGCUUCCCUUUGGACUGU
hsa-miR-520b aaagugcuuuuuuagaggg
hsa-miR-520c aaagugcuuuuuuaggggug
hsa-miR-520d aaaguguuugugggguggguu