Gene Page:MMRN1
年代ummary?
| GeneID | 22915 |
| 年代ymbol | MMRN1 |
| 年代ynonyms | ECM|EMILIN4|GPIa*|MMRN |
| Description | multimerin 1 |
| Reference | MIM:601456|HGNC:HGNC:7178|Ensembl:ENSG00000138722|HPRD:03267|Vega:OTTHUMG00000130947 |
| Gene type | protein-coding |
| Map location | 4q22 |
| Pascal p-value | 0.004 |
| eGene | 小脑 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
年代ection I. Genetics and epigenetics annotation
年代ection II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
年代C: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
年代T1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | 年代pearman's Correlation |
| WDR48 | 0.96 | 0.96 |
| DIS3 | 0.96 | 0.96 |
| ZNF644 | 0.95 | 0.95 |
| WDR3 | 0.95 | 0.96 |
| ZNF131 | 0.95 | 0.96 |
| 年代UPT16H | 0.95 | 0.96 |
| HMG20A | 0.94 | 0.95 |
| KIAA1429 | 0.94 | 0.95 |
| BCLAF1 | 0.94 | 0.96 |
| NCBP1 | 0.94 | 0.95 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | 年代pearman's Correlation |
| FXYD1 | -0.75 | -0.88 |
| AF347015.31 | -0.75 | -0.87 |
| MT-CO2 | -0.74 | -0.87 |
| IFI27 | -0.74 | -0.87 |
| HIGD1B | -0.73 | -0.88 |
| TSC22D4 | -0.72 | -0.81 |
| HLA-F | -0.72 | -0.78 |
| AF347015.33 | -0.72 | -0.83 |
| AIFM3 | -0.72 | -0.78 |
| MT-CYB | -0.71 | -0.83 |
年代ection V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | 89 | 56 | All SZGR 2.0 genes in this pathway |
| REACTOME HEMOSTASIS | 466 | 331 | All SZGR 2.0 genes in this pathway |
| REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION | 208 | 138 | All SZGR 2.0 genes in this pathway |
| GAZDA DIAMOND BLACKFAN ANEMIA ERYTHROID DN | 493 | 298 | All SZGR 2.0 genes in this pathway |
| CASORELLI ACUTE PROMYELOCYTIC LEUKEMIA DN | 663 | 425 | All SZGR 2.0 genes in this pathway |
| OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN | 275 | 168 | All SZGR 2.0 genes in this pathway |
| KIM MYCN AMPLIFICATION TARGETS UP | 92 | 64 | All SZGR 2.0 genes in this pathway |
| 年代CHAEFFER PROSTATE DEVELOPMENT 6HR UP | 176 | 115 | All SZGR 2.0 genes in this pathway |
| 年代ANA TNF SIGNALING DN | 90 | 57 | All SZGR 2.0 genes in this pathway |
| TAVOR CEBPA TARGETS DN | 30 | 21 | All SZGR 2.0 genes in this pathway |
| GEORGANTAS HSC MARKERS | 71 | 47 | All SZGR 2.0 genes in this pathway |
| DURCHDEWALD SKIN CARCINOGENESIS UP | 88 | 47 | All SZGR 2.0 genes in this pathway |
| YOSHIMURA MAPK8 TARGETS UP | 1305 | 895 | All SZGR 2.0 genes in this pathway |
| VALK AML CLUSTER 1 | 28 | 19 | All SZGR 2.0 genes in this pathway |
| PEDRIOLI MIR31 TARGETS DN | 418 | 245 | All SZGR 2.0 genes in this pathway |
| GENTLES LEUKEMIC STEM CELL UP | 29 | 15 | All SZGR 2.0 genes in this pathway |
| NABA ECM GLYCOPROTEINS | 196 | 99 | All SZGR 2.0 genes in this pathway |
| NABA CORE MATRISOME | 275 | 148 | All SZGR 2.0 genes in this pathway |
| NABA MATRISOME | 1028 | 559 | All SZGR 2.0 genes in this pathway |