Gene Page:EFR3B
Summary?
| GeneID | 22979 |
| Symbol | EFR3B |
| Synonyms | KIAA0953 |
| Description | EFR3 homolog B |
| Reference | MIM:616797|HGNC:HGNC:29155|Ensembl:ENSG00000084710|Vega:OTTHUMG00000151988 |
| Gene type | protein-coding |
| Map location | 2p23.3 |
| Pascal p-value | 7.578E-4 |
| 支持 | G2Cdb.humanPSD G2Cdb.humanPSP |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| RAI14 | 0.91 | 0.92 |
| MLLT4 | 0.91 | 0.94 |
| NFIB | 0.90 | 0.88 |
| C10orf12 | 0.89 | 0.90 |
| ZNF462 | 0.89 | 0.94 |
| MYST4 | 0.88 | 0.95 |
| SETBP1 | 0.87 | 0.92 |
| SOX11 | 0.87 | 0.88 |
| ITSN1 | 0.87 | 0.88 |
| MYST3 | 0.87 | 0.95 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| TNFSF12 | -0.55 | -0.67 |
| LHPP | -0.54 | -0.61 |
| SLC9A3R2 | -0.54 | -0.42 |
| C5orf53 | -0.53 | -0.78 |
| TMEM54 | -0.53 | -0.64 |
| FBXO2 | -0.53 | -0.69 |
| PTH1R | -0.53 | -0.71 |
| HLA-F | -0.52 | -0.75 |
| PPAP2A | -0.52 | -0.51 |
| SLC16A11 | -0.52 | -0.64 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| BERTUCCI MEDULLARY VS DUCTAL BREAST CANCER DN | 169 | 118 | All SZGR 2.0 genes in this pathway |
| CHARAFE BREAST CANCER LUMINAL VS BASAL UP | 380 | 215 | All SZGR 2.0 genes in this pathway |
| DUTERTRE ESTRADIOL RESPONSE 24HR DN | 505 | 328 | All SZGR 2.0 genes in this pathway |
| GOBERT OLIGODENDROCYTE DIFFERENTIATION DN | 1080 | 713 | All SZGR 2.0 genes in this pathway |
| FORTSCHEGGER PHF8 TARGETS DN | 784 | 464 | All SZGR 2.0 genes in this pathway |
| RATTENBACHER BOUND BY CELF1 | 467 | 251 | All SZGR 2.0 genes in this pathway |