Summary
基因 23022
象征 pALLD
Synonyms CGI-151 | CGI151 | myn | pnca1 | sih002
Description palladin,细胞骨架相关蛋白
Reference MIM:608092|HGNC:HGNC:17068|Ensembl:ENSG00000129116|HPRD:09731|Vega:OTTHUMG00000161097
基因类型 蛋白质编码
地图上的位置 4q32.3
Pascal P值 0.961
Sherlock p-value 0.603
主持人 小脑
Myers' cis & trans

Gene in Data Sources
基因集名称 基因的方法设置 Description 信息
简历:Gwascat Genome-wide Association Studies 该数据集包括与精神分裂症相关的560个SNP。总共将486个基因映射到50kb内的这些SNP。
简历:PGCNP 全基因组协会研究 GWAS
PMID:cooccur High-throughput literature-search PubMed中的系统搜索与SCZ关键字共发生的基因。总共包括3027个基因。
表达 Meta-analysis of gene expression pvalue: 1.372
Literature High-throughput literature-search Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias 点击显示详细信息

Section I. Genetics and epigenetics annotation

@EQTL注释

SNP ID 染色体 位置 主持人 Gene Entrez ID PVALUE QVALUE TSS距离 EQTL类型
rs1039386 CHR4 169673828 pALLD 23022 0.19 顺式
RS2655880 CHR12 60797980 pALLD 23022 0.18 反式

第二节。转录组注释

一般基因表达(GTEX)

无法使用

时间变化的基因表达(brainspan)

Footnote:
SC:亚皮质区域;SM:感觉运动区域;FC:额叶皮层;和TP:颞顶皮层
ST1:胎儿(13-26个概念后周),ST2:婴儿早期至童年(4个月至11年)和ST3:青春期至成年期(13-23年)
所示的栏表示表达分布的较低25%和上层25%。

No co-expressed genes in brain regions


第三节。基因本体论注释

分子功能 去学期 证据 神经关键字 PubMed ID
GO:0003779 肌动蛋白结合 IEA -
去:0005515 蛋白质结合 IPI 11598191
GO:0051371 肌肉α-肌动蛋白结合 TAS 16125169
生物过程 去学期 证据 神经关键字 PubMed ID
去:0007010 细胞骨架组织 nas 11598191
Cellular component 去学期 证据 神经关键字 PubMed ID
去:0005856 细胞骨架 IEA -
去:0005634 nucleus 艾达 11598191
去:0005737 cytoplasm IEA -
去:0005884 actin filament 艾达 11598191

Section V. Pathway annotation

路径名 路径大小 # SZGR 2.0 genes in pathway 信息
中村肿瘤区周围与中央 285 181 All SZGR 2.0 genes in this pathway
刘前列腺癌DN 481 290 All SZGR 2.0 genes in this pathway
ONKEN UVEAL MELANOMA DN 526 357 All SZGR 2.0 genes in this pathway
Schuetz乳腺癌导管侵入性 351 230 All SZGR 2.0 genes in this pathway
Gary CD5目标DN 431 263 All SZGR 2.0 genes in this pathway
周的炎症反应生活 485 293 All SZGR 2.0 genes in this pathway
VMYB vs CMYB DN的LIU目标 43 30 All SZGR 2.0 genes in this pathway
DOANE RESPONSE TO ANDROGEN DN 241 146 All SZGR 2.0 genes in this pathway
Laiho结直肠癌锯齿状 112 71 All SZGR 2.0 genes in this pathway
NUP98 HOXA9 Fusion 8D的Takeda目标 157 91 All SZGR 2.0 genes in this pathway
NUP98 HOXA9 Fusion 10D的Takeda目标 194 122 All SZGR 2.0 genes in this pathway
NUP98 HOXA9 Fusion 16D的Takeda目标 175 108 All SZGR 2.0 genes in this pathway
HOEBEKE LYMPHOID STEM CELL UP 95 64 All SZGR 2.0 genes in this pathway
runx1 runx1t1融合HSC的TONKS目标UP 185 126 All SZGR 2.0 genes in this pathway
UDayakumar Med1靶向DN 240 171 All SZGR 2.0 genes in this pathway
Lee神经Crest干细胞DN 118 79 All SZGR 2.0 genes in this pathway
Nagashima NRG1信号向上发出 176 123 All SZGR 2.0 genes in this pathway
chebotaev gr目标dn 120 73 All SZGR 2.0 genes in this pathway
Lindgren膀胱癌簇2A DN 141 84 All SZGR 2.0 genes in this pathway
环氧化物素的浓凋亡 239 157 All SZGR 2.0 genes in this pathway
GAUSSMANN MLL AF4 FUSION TARGETS G UP 238 135 All SZGR 2.0 genes in this pathway
McBryan Pubertal乳房4 5WK 271 175 All SZGR 2.0 genes in this pathway
McBryan Pubertal乳房6 7WK DN 79 54 All SZGR 2.0 genes in this pathway
哈马凋亡通过Trail Up 584 356 All SZGR 2.0 genes in this pathway
Abdulrahman肾癌VHL DN 14 9 All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER CLUSTER 2B 392 251 All SZGR 2.0 genes in this pathway
牛津拉拉或拉尔布靶向DN 24 17 All SZGR 2.0 genes in this pathway
Mohankumar TLX1靶向 414 287 All SZGR 2.0 genes in this pathway
GROSS HYPOXIA VIA ELK3 AND HIF1A UP 142 104 All SZGR 2.0 genes in this pathway
buytaert光动力疗法压力 811 508 All SZGR 2.0 genes in this pathway
WEI mir34a目标 148 97 All SZGR 2.0 genes in this pathway
Schaeffer前列腺开发6小时DN 514 330 All SZGR 2.0 genes in this pathway
Schaeffer前列腺开发48小时DN 428 306 All SZGR 2.0 genes in this pathway
甜蜜的克拉斯靶向 84 51 All SZGR 2.0 genes in this pathway
Flechner活检肾脏移植OK vs捐助者 555 346 All SZGR 2.0 genes in this pathway
石匠食道癌发生DN 7 6 All SZGR 2.0 genes in this pathway
LEI MYB目标 318 215 All SZGR 2.0 genes in this pathway
HADDAD T淋巴细胞和NK祖细胞DN 63 41 All SZGR 2.0 genes in this pathway
Zhan多发性骨髓瘤MS 48 32 All SZGR 2.0 genes in this pathway
CUI TCF21目标2 DN 830 547 All SZGR 2.0 genes in this pathway
阿尔茨海默氏症疾病 1691 1088 All SZGR 2.0 genes in this pathway
大脑衰老 262 186 All SZGR 2.0 genes in this pathway
贝尔德糖尿病性肾病DN 434 302 All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 1 528 324 All SZGR 2.0 genes in this pathway
RIGGINS TAMOXIFEN RESISTANCE DN 220 147 All SZGR 2.0 genes in this pathway
阿塞维多肝癌 973 570 All SZGR 2.0 genes in this pathway
Acevedo肝癌,H3K27me3 UP 295 149 All SZGR 2.0 genes in this pathway
podar对Apaphostin的反应 147 98 All SZGR 2.0 genes in this pathway
Tacker吉西他滨抵抗 79 40 All SZGR 2.0 genes in this pathway
罗斯白血病与MLL融合 78 49 All SZGR 2.0 genes in this pathway
Lee早期T淋巴细胞向上 107 59 All SZGR 2.0 genes in this pathway
米利伪虫 43 27 All SZGR 2.0 genes in this pathway
米利假足趋化趋化性 74 45 All SZGR 2.0 genes in this pathway
米利假足 518 299 All SZGR 2.0 genes in this pathway
YAGI AML WITH T 9 11 TRANSLOCATION 130 87 All SZGR 2.0 genes in this pathway
Fournier腺泡开发2 277 172 All SZGR 2.0 genes in this pathway
开罗肝母细胞瘤 207 143 All SZGR 2.0 genes in this pathway
Chicas RB1目标汇合 567 365 All SZGR 2.0 genes in this pathway
lu eszh2靶向DN 414 237 All SZGR 2.0 genes in this pathway
DUTERTRE ESTRADIOL RESPONSE 24HR DN 505 328 All SZGR 2.0 genes in this pathway
Gabriely miR21靶标 289 187 All SZGR 2.0 genes in this pathway
pasini suz12靶向DN 315 215 All SZGR 2.0 genes in this pathway
STAT3的Azare肿瘤转化 121 70 All SZGR 2.0 genes in this pathway
Gobert少突胶质细胞分化 570 339 All SZGR 2.0 genes in this pathway
Zwang 1类由EGF瞬时诱导 516 308 All SZGR 2.0 genes in this pathway

第六节。microRNA注释

mirna家族 目标位置 miRNA ID mirna seq
UTR开始 UTR结束 匹配方法
mir-1/206 951 957 1a HSA-MIR-1 UGGAAUGUAAAGAAGUAUGUA
hsa-miR-206SZ Uggaauguaaggaagugugugg
HSA-MIR-613 aggaauguucuuugcc
mir-124.1 762 769 1A,M8 HSA-MIR-124A UUAAGGCACGCGGUGAAUGCCA
mir-124/506 529 535 M8 HSA-MIR-506 uaaggcacccuucugugaguaga
HSA-MIR-124brain UAAGGCACGCGGUGAAUGCC
HSA-MIR-506 uaaggcacccuucugugaguaga
HSA-MIR-124brain UAAGGCACGCGGUGAAUGCC
miR-181 2069 2075 M8 HSA-MIR-181Abrain AACAUUCAACGCUGUCGGUGAGU
HSA-MIR-181BSZ aacauucauugcugucggggg
HSA-MIR-181Cbrain AACAUUCAACCUGUCGGUGAGU
HSA-MIR-181Dbrain aacauucauuguugucggggguggguu
miR-182 2055 2062 1A,M8 HSA-MIR-182 uuuggcaaugguagaacucaca
HSA-MIR-182 uuuggcaaugguagaacucaca
mir-19 400 406 1a HSA-MIR-19A ugugcaaauaugauaugaaaacuga
HSA-MIR-19B UGUGCAAAUCCAUGCAAAACUGA
mir-23 2071 2077 M8 HSA-MIR-23Abrain AUCACAUUGCCAGGGAUUUCC
HSA-MIR-23Bbrain aucacauugccagggauuacc
mir-320 1851 1857 M8 hsa-miR-320 aaaagcugggugagaggggcgaa
mir-323 2071 2077 1a hsa-miR-323brain gcacauuacggucgaccucu
miR-376 1687 1693 1a HSA-MIR-376A aucauagaaaaauccacgu
HSA-MIR-376B AUCAUAGAGGAAAAUCCAUGUU
mir-96 469 475 1a HSA-MIR-96brain uuuggcacuagcacauuuuugc