Gene Page:FBXO28
Summary?
| GeneID | 23219 |
| Symbol | FBXO28 |
| Synonyms | CENP-30|Fbx28 |
| Description | F-box protein 28 |
| Reference | MIM:609100|HGNC:HGNC:29046|Ensembl:ENSG00000143756|HPRD:12367|Vega:OTTHUMG00000037495 |
| Gene type | protein-coding |
| Map location | 1q42.11 |
| Sherlock p-value | 0.016 |
| Fetal beta | -0.357 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| SHISA4 | 0.87 | 0.87 |
| MARCH2 | 0.85 | 0.84 |
| CISD3 | 0.85 | 0.87 |
| C5orf32 | 0.84 | 0.85 |
| CIB1 | 0.84 | 0.84 |
| COX5B | 0.84 | 0.85 |
| TEX264 | 0.83 | 0.80 |
| ISOC2 | 0.82 | 0.82 |
| SULT1A1 | 0.82 | 0.78 |
| BLVRB | 0.82 | 0.83 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| THOC2 | -0.65 | -0.73 |
| RTF1 | -0.65 | -0.67 |
| ANKRD12 | -0.63 | -0.67 |
| MAP4K4 | -0.63 | -0.68 |
| ZNF326 | -0.62 | -0.68 |
| SUV420H1 | -0.62 | -0.62 |
| ZNF605 | -0.61 | -0.60 |
| ZC3H13 | -0.61 | -0.62 |
| AC004017.1 | -0.61 | -0.59 |
| ZNF551 | -0.61 | -0.60 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| TURASHVILI BREAST LOBULAR CARCINOMA VS DUCTAL NORMAL UP | 69 | 38 | All SZGR 2.0 genes in this pathway |
| GARY CD5 TARGETS DN | 431 | 263 | All SZGR 2.0 genes in this pathway |
| WANG LMO4 TARGETS DN | 352 | 225 | All SZGR 2.0 genes in this pathway |
| MULLIGHAN NPM1 MUTATED SIGNATURE 1 UP | 276 | 165 | All SZGR 2.0 genes in this pathway |
| MULLIGHAN NPM1 SIGNATURE 3 UP | 341 | 197 | All SZGR 2.0 genes in this pathway |
| KINSEY TARGETS OF EWSR1 FLII FUSION UP | 1278 | 748 | All SZGR 2.0 genes in this pathway |
| DODD NASOPHARYNGEAL CARCINOMA DN | 1375 | 806 | All SZGR 2.0 genes in this pathway |
| SHEN SMARCA2 TARGETS UP | 424 | 268 | All SZGR 2.0 genes in this pathway |
| ALCALAY AML BY NPM1 LOCALIZATION UP | 140 | 83 | All SZGR 2.0 genes in this pathway |
| DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP | 314 | 201 | All SZGR 2.0 genes in this pathway |
| BROWNE HCMV INFECTION 48HR UP | 180 | 125 | All SZGR 2.0 genes in this pathway |
| ACEVEDO肝癌了 | 973 | 570 | All SZGR 2.0 genes in this pathway |
| HIRSCH CELLULAR TRANSFORMATION SIGNATURE UP | 242 | 159 | All SZGR 2.0 genes in this pathway |
| RAO BOUND BY SALL4 ISOFORM B | 517 | 302 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY | 1839 | 928 | All SZGR 2.0 genes in this pathway |