Gene Page:ATP13A2
Summary?
| GeneID | 23400 |
| Symbol | ATP13A2 |
| Synonyms | CLN12|HSA9947|KRPPD|PARK9 |
| Description | ATPase 13A2 |
| Reference | MIM:610513|HGNC:HGNC:30213|Ensembl:ENSG00000159363|HPRD:13677|Vega:OTTHUMG00000002293 |
| Gene type | protein-coding |
| Map location | 1p36 |
| Pascal p-value | 0.008 |
| Sherlock p-value | 0.856 |
| 支持 | CompositeSet Darnell FMRP targets Ascano FMRP targets |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
某场效应晶体管al (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| SNAP47 | 0.92 | 0.83 |
| CAPZB | 0.90 | 0.82 |
| PPP5C | 0.90 | 0.86 |
| MED8 | 0.89 | 0.82 |
| IDH3B | 0.89 | 0.81 |
| TBRG4 | 0.89 | 0.85 |
| AAMP | 0.89 | 0.82 |
| PMPCA | 0.88 | 0.82 |
| TCF25 | 0.88 | 0.80 |
| NDUFA10 | 0.88 | 0.81 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.8 | -0.77 | -0.57 |
| AF347015.21 | -0.77 | -0.57 |
| AF347015.2 | -0.75 | -0.53 |
| MT-CO2 | -0.74 | -0.53 |
| MT-CYB | -0.74 | -0.55 |
| AF347015.26 | -0.74 | -0.56 |
| AF347015.15 | -0.73 | -0.55 |
| AF347015.18 | -0.73 | -0.62 |
| AF347015.31 | -0.72 | -0.54 |
| AF347015.33 | -0.72 | -0.55 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| GRAESSMANN APOPTOSIS BY SERUM DEPRIVATION DN | 234 | 147 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY DOXORUBICIN UP | 1142 | 669 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN RESPONSE TO MC AND DOXORUBICIN UP | 612 | 367 | All SZGR 2.0 genes in this pathway |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | 800 | 473 | All SZGR 2.0 genes in this pathway |
| MATTIOLI MULTIPLE MYELOMA WITH 14Q32 TRANSLOCATIONS | 36 | 25 | All SZGR 2.0 genes in this pathway |
| LIAO METASTASIS | 539 | 324 | All SZGR 2.0 genes in this pathway |
| STARK HYPPOCAMPUS 22Q11 DELETION UP | 53 | 40 | All SZGR 2.0 genes in this pathway |
| MATSUDA NATURAL KILLER DIFFERENTIATION | 475 | 313 | All SZGR 2.0 genes in this pathway |
| ZHAN MULTIPLE MYELOMA MF UP | 47 | 27 | All SZGR 2.0 genes in this pathway |
| LEE CALORIE RESTRICTION NEOCORTEX UP | 83 | 66 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE DN | 1237 | 837 | All SZGR 2.0 genes in this pathway |
| HELLER SILENCED BY METHYLATION UP | 282 | 183 | All SZGR 2.0 genes in this pathway |
| HELLER HDAC TARGETS UP | 317 | 208 | All SZGR 2.0 genes in this pathway |
| HELLER HDAC TARGETS SILENCED BY METHYLATION UP | 461 | 298 | All SZGR 2.0 genes in this pathway |
| HAN SATB1 TARGETS DN | 442 | 275 | All SZGR 2.0 genes in this pathway |
| CHEN METABOLIC SYNDROM NETWORK | 1210 | 725 | All SZGR 2.0 genes in this pathway |
| CHYLA CBFA2T3 TARGETS UP | 387 | 225 | All SZGR 2.0 genes in this pathway |
| PILON KLF1 TARGETS DN | 1972 | 1213 | All SZGR 2.0 genes in this pathway |
| GOBERT OLIGODENDROCYTE DIFFERENTIATION DN | 1080 | 713 | All SZGR 2.0 genes in this pathway |
| HOLLEMAN VINCRISTINE RESISTANCE B ALL DN | 15 | 10 | All SZGR 2.0 genes in this pathway |
| HOLLEMAN VINCRISTINE RESISTANCE ALL DN | 19 | 11 | All SZGR 2.0 genes in this pathway |