Gene Page:ZFPM2

Summary?
GeneID 23414
Symbol ZFPM2
Synonyms DIH3|FOG2|SRXY9|ZC2HC11B|ZNF89B|hFOG-2
Description zinc finger protein, FOG family member 2
Reference MIM:603693|HGNC:HGNC:16700|Ensembl:ENSG00000169946|HPRD:04737|Vega:OTTHUMG00000164818
Gene type protein-coding
Map location 8q23
Pascal p-value 0.003
Fetal beta 0.286
DMG 1 (# studies)
eGene Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:GWASdb Genome-wide Association Studies GWASdb records for schizophrenia
CV:PGCnp Genome-wide Association Study GWAS
DMG:Wockner_2014 Genome-wide DNA methylation analysis This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 1
PMID:cooccur High-throughput literature-search Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
Literature High-throughput literature-search Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias Click to show details

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

Probe Chromosome Position Nearest gene P (dis) Beta (dis) FDR (dis) Study
cg17154315 8 106331166 ZFPM2 2.17E-4 -0.296 0.036 DMG:Wockner_2014

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs2816169 chr1 179210675 ZFPM2 23414 0.19 trans
rs17572651 chr1 218943612 ZFPM2 23414 1.756E-5 trans
rs17048849 chr2 129626025 ZFPM2 23414 0.03 trans
rs2197597 chr2 129638077 ZFPM2 23414 0 trans
rs2897468 chr2 129711721 ZFPM2 23414 0.01 trans
rs16829545 chr2 151977407 ZFPM2 23414 1.301E-24 trans
rs7584986 chr2 184111432 ZFPM2 23414 5.309E-7 trans
rs6741060 chr2 217169088 ZFPM2 23414 0 trans
rs9810143 chr3 5060209 ZFPM2 23414 0.04 trans
rs520325 chr3 165361016 ZFPM2 23414 0.17 trans
snp_a-1815771 0 ZFPM2 23414 0.01 trans
rs17020035 chr4 93873810 ZFPM2 23414 0.06 trans
rs17020058 chr4 93915972 ZFPM2 23414 0.02 trans
rs17020066 chr4 93921055 ZFPM2 23414 0.02 trans
rs2183142 chr4 159232695 ZFPM2 23414 0.04 trans
rs4488887 chr4 177695833 ZFPM2 23414 0.09 trans
rs1472616 chr5 61026501 ZFPM2 23414 0.18 trans
rs10474151 chr5 84286402 ZFPM2 23414 0.03 trans
rs3777174 chr5 95280552 ZFPM2 23414 0.13 trans
rs6893788 chr5 95335085 ZFPM2 23414 0.13 trans
rs10515234 chr5 95336330 ZFPM2 23414 0.13 trans
rs979348 chr5 97074134 ZFPM2 23414 0.1 trans
rs13191953 chr6 24151042 ZFPM2 23414 0.15 trans
rs12196880 chr6 24313746 ZFPM2 23414 0.02 trans
rs17149888 chr7 24738371 ZFPM2 23414 0.11 trans
rs10253181 chr7 26563022 ZFPM2 23414 0.14 trans
rs12706918 chr7 80266147 ZFPM2 23414 0.18 trans
rs2305128 chr8 120599486 ZFPM2 23414 0.14 trans
rs2393316 chr10 59333070 ZFPM2 23414 7.989E-4 trans
rs17124813 chr10 110347464 ZFPM2 23414 0.18 trans
rs11061703 chr12 1436977 ZFPM2 23414 0.15 trans
rs7337967 chr13 53519044 ZFPM2 23414 0.2 trans
rs4112777 chr13 99281457 ZFPM2 23414 6.886E-4 trans
rs9989228 chr14 37809252 ZFPM2 23414 0.04 trans
rs16955618 chr15 29937543 ZFPM2 23414 3.323E-24 trans
rs2077735 chr15 58479024 ZFPM2 23414 0.01 trans
rs4795850 chr17 32383815 ZFPM2 23414 0.11 trans
rs4795851 chr17 32384050 ZFPM2 23414 0.11 trans
rs12458173 chr18 31430166 ZFPM2 23414 0.02 trans
rs6046679 chr20 20146874 ZFPM2 23414 0.01 trans
rs1041786 chr21 22617710 ZFPM2 23414 3.919E-4 trans
rs16986332 chrX 10958354 ZFPM2 23414 0.1 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION 132 101 All SZGR 2.0 genes in this pathway
REACTOME HEMOSTASIS 466 331 All SZGR 2.0 genes in this pathway
SCHUETZ BREAST CANCER DUCTAL INVASIVE UP 351 230 All SZGR 2.0 genes in this pathway
WAMUNYOKOLI OVARIAN CANCER LMP DN 199 124 All SZGR 2.0 genes in this pathway
DELYS THYROID CANCER DN 232 154 All SZGR 2.0 genes in this pathway
BERENJENO通过RHOA转换 536 340 All SZGR 2.0 genes in this pathway
RICKMAN HEAD AND NECK CANCER F 54 32 All SZGR 2.0 genes in this pathway
OKUMURA INFLAMMATORY RESPONSE LPS 183 115 All SZGR 2.0 genes in this pathway
KANG IMMORTALIZED BY TERT DN 102 67 All SZGR 2.0 genes in this pathway
WANG SMARCE1 TARGETS DN 371 218 All SZGR 2.0 genes in this pathway
CUI TCF21 TARGETS 2 UP 428 266 All SZGR 2.0 genes in this pathway
LIU SMARCA4 TARGETS 64 39 All SZGR 2.0 genes in this pathway
阿塞维多METHYLATED IN LIVER CANCER DN 940 425 All SZGR 2.0 genes in this pathway
HOFFMANN IMMATURE TO MATURE B LYMPHOCYTE UP 43 34 All SZGR 2.0 genes in this pathway
CARD MIR302A TARGETS 77 62 All SZGR 2.0 genes in this pathway