Gene Page:TSSK2

Summary?
GeneID 23617
Symbol TSSK2
Synonyms DGS-G|SPOGA2|STK22B|TSK2
Description testis specific serine kinase 2
Reference MIM:610710|HGNC:HGNC:11401|Ensembl:ENSG00000206203|HPRD:10255|Vega:OTTHUMG00000150118
Gene type protein-coding
Map location 22q11.21
Pascal p-value 0.018
eGene Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene set Description Info
CNV:YES Copy number variation studies Manual curation
GSMA_I Genome scan meta-analysis Psr: 0.031

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs10994209 chr10 61877705 TSSK2 23617 0.13 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 -26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section III. Gene Ontology annotation

Molecular function 去的术语 Evidence Neuro keywords PubMed ID
GO:0000166 nucleotide binding IEA -
GO:0000287 magnesium ion binding ISS -
GO:0005515 protein binding 新闻学会 15044604
GO:0005524 ATP binding ISS -
GO:0004674 protein serine/threonine kinase activity ISS -
GO:0016740 transferase activity IEA -
Biological process 去的术语 Evidence Neuro keywords PubMed ID
GO:0006468 protein amino acid phosphorylation ISS -
GO:0007283 spermatogenesis IEA -
GO:0007275 multicellular organismal development IEA -
GO:0030154 cell differentiation IEA -
Cellular component 去的术语 Evidence Neuro keywords PubMed ID
GO:0005737 cytoplasm IEA -

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
KIM WT1 TARGETS 8HR DN 129 84 All SZGR 2.0 genes in this pathway
AFFAR YY1 TARGETS UP 214 133 All SZGR 2.0 genes in this pathway
MIKKELSEN IPS HCP WITH H3 UNMETHYLATED 80 50 All SZGR 2.0 genes in this pathway
WEBER METHYLATED ICP IN FIBROBLAST 22 9 All SZGR 2.0 genes in this pathway
MIKKELSEN ES HCP WITH H3 UNMETHYLATED 63 31 All SZGR 2.0 genes in this pathway
MIKKELSEN MEF HCP WITH H3 UNMETHYLATED 228 119 All SZGR 2.0 genes in this pathway
WAKABAYASHI ADIPOGENESIS PPARG BOUND 8D 658 397 All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family Target position miRNA ID miRNA seq
UTR start UTR end Match method
miR-140 129 135 m8 hsa-miR-140brain AGUGGUUUUACCCUAUGGUAG
miR-299-5p 128 134 1A hsa-miR-299-5p UGGUUUACCGUCCCACAUACAU
miR-500 105 112 1A,m8 hsa-miR-500 AUGCACCUGGGCAAGGAUUCUG