Gene Page:FTH1

Summary?
GeneID 2495
Symbol FTH1
Synonyms FHC|FTH|FTHL6|HFE5|PIG15|PLIF
Description ferritin, heavy polypeptide 1
Reference MIM:134770|HGNC:HGNC:3976|Ensembl:ENSG00000167996|HPRD:00615|Vega:OTTHUMG00000166217
Gene type protein-coding
Map location 11q13
Pascal p-value 0.655
Sherlock p-value 0.7
eGene Myers' cis & trans
Support CompositeSet

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
PMID:cooccur High-throughput literature-search 系统本身arch in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
Literature High-throughput literature-search Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias Click to show details

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs11230726 chr11 61275103 FTH1 2495 0.14 cis
rs4491879 chr3 189373908 FTH1 2495 0.14 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
KEGG PORPHYRIN AND CHLOROPHYLL METABOLISM 41 23 All SZGR 2.0 genes in this pathway
PID MYC REPRESS PATHWAY 63 52 All SZGR 2.0 genes in this pathway
REACTOME MEMBRANE TRAFFICKING 129 74 All SZGR 2.0 genes in this pathway
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING 60 31 All SZGR 2.0 genes in this pathway
REACTOME TRANSMEMBRANE TRANSPORT OF SMALL MOLECULES 413 270 All SZGR 2.0 genes in this pathway
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS 53 27 All SZGR 2.0 genes in this pathway
REACTOME IRON UPTAKE AND TRANSPORT 36 18 All SZGR 2.0 genes in this pathway
NAKAMURA TUMOR ZONE PERIPHERAL VS CENTRAL DN 634 384 All SZGR 2.0 genes in this pathway
NAM FXYD5 TARGETS DN 18 11 All SZGR 2.0 genes in this pathway
GAZDA DIAMOND BLACKFAN ANEMIA PROGENITOR UP 39 25 All SZGR 2.0 genes in this pathway
ODONNELL TFRC TARGETS UP 456 228 All SZGR 2.0 genes in this pathway
TIEN INTESTINE PROBIOTICS 24HR DN 214 133 All SZGR 2.0 genes in this pathway
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP 66 47 All SZGR 2.0 genes in this pathway
GOZGIT ESR1 TARGETS DN 781 465 All SZGR 2.0 genes in this pathway
ENK UV RESPONSE EPIDERMIS UP 293 179 All SZGR 2.0 genes in this pathway
CAIRO PML TARGETS BOUND BY MYC DN 14 12 All SZGR 2.0 genes in this pathway
LASTOWSKA NEUROBLASTOMA COPY NUMBER DN 800 473 All SZGR 2.0 genes in this pathway
DUTTA APOPTOSIS VIA NFKB 33 25 All SZGR 2.0 genes in this pathway
CAVARD LIVER CANCER MALIGNANT VS BENIGN 32 19 All SZGR 2.0 genes in this pathway
DIRMEIER LMP1 RESPONSE EARLY 66 48 All SZGR 2.0 genes in this pathway
WANG HCP PROSTATE CANCER 111 69 All SZGR 2.0 genes in this pathway
JOHANSSON BRAIN CANCER EARLY VS LATE DN 45 35 All SZGR 2.0 genes in this pathway
GROSS ELK3 TARGETS DN 32 17 All SZGR 2.0 genes in this pathway
BUYTAERT PHOTODYNAMIC THERAPY STRESS UP 811 508 All SZGR 2.0 genes in this pathway
COLIN PILOCYTIC ASTROCYTOMA VS GLIOBLASTOMA UP 35 32 All SZGR 2.0 genes in this pathway
BENPORATH MYC MAX TARGETS 775 494 All SZGR 2.0 genes in this pathway
LE EGR2 TARGETS DN 108 84 All SZGR 2.0 genes in this pathway
HOUSTIS ROS 36 29 All SZGR 2.0 genes in this pathway
GNATENKO PLATELET SIGNATURE 48 28 All SZGR 2.0 genes in this pathway
FLECHNER PBL KIDNEY TRANSPLANT OK VS DONOR UP 151 100 All SZGR 2.0 genes in this pathway
FLECHNER PBL KIDNEY TRANSPLANT REJECTED VS OK DN 51 35 All SZGR 2.0 genes in this pathway
SANA TNF SIGNALING UP 83 56 All SZGR 2.0 genes in this pathway
ADDYA ERYTHROID DIFFERENTIATION BY HEMIN 73 47 All SZGR 2.0 genes in this pathway
TAKAO RESPONSE TO UVB RADIATION UP 86 55 All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS LATE PROGENITOR 544 307 All SZGR 2.0 genes in this pathway
NATSUME RESPONSE TO INTERFERON BETA DN 52 33 All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE UP 1691 1088 All SZGR 2.0 genes in this pathway
TSENG IRS1 TARGETS DN 135 88 All SZGR 2.0 genes in this pathway
JIANG HYPOXIA NORMAL 311 205 All SZGR 2.0 genes in this pathway
BANDRES RESPONSE TO CARMUSTIN MGMT 48HR DN 161 105 All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 6HR UP 953 554 All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 24HR UP 783 442 All SZGR 2.0 genes in this pathway
KIM LRRC3B TARGETS 30 24 All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 3 720 440 All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 STIMULATED 1022 619 All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 UNSTIMULATED 1229 713 All SZGR 2.0 genes in this pathway
KANG CISPLATIN RESISTANCE UP 19 11 All SZGR 2.0 genes in this pathway
PODAR RESPONSE TO ADAPHOSTIN UP 147 98 All SZGR 2.0 genes in this pathway
BEIER GLIOMA STEM CELL DN 66 42 All SZGR 2.0 genes in this pathway
HELLEBREKERS SILENCED DURING TUMOR ANGIOGENESIS 80 56 All SZGR 2.0 genes in this pathway
TOOKER GEMCITABINE RESISTANCE UP 79 40 All SZGR 2.0 genes in this pathway
RUTELLA RESPONSE TO CSF2RB AND IL4 UP 338 225 All SZGR 2.0 genes in this pathway
RUTELLA RESPONSE TO HGF UP 418 282 All SZGR 2.0 genes in this pathway
RUTELLA RESPONSE TO HGF VS CSF2RB AND IL4 UP 408 276 All SZGR 2.0 genes in this pathway
SHEDDEN肺癌好生存A4 196 124 All SZGR 2.0 genes in this pathway
HSIAO HOUSEKEEPING GENES 389 245 All SZGR 2.0 genes in this pathway
BOYAULT LIVER CANCER SUBCLASS G3 UP 188 121 All SZGR 2.0 genes in this pathway
KOBAYASHI EGFR SIGNALING 24HR UP 101 65 All SZGR 2.0 genes in this pathway
DANG REGULATED BY MYC DN 253 192 All SZGR 2.0 genes in this pathway
KARLSSON TGFB1 TARGETS DN 207 139 All SZGR 2.0 genes in this pathway
MARTENS TRETINOIN RESPONSE DN 841 431 All SZGR 2.0 genes in this pathway
DUTERTRE ESTRADIOL RESPONSE 24HR DN 505 328 All SZGR 2.0 genes in this pathway
WAKABAYASHI ADIPOGENESIS PPARG RXRA BOUND 8D 882 506 All SZGR 2.0 genes in this pathway
DELACROIX RARG BOUND MEF 367 231 All SZGR 2.0 genes in this pathway
BOUDOUKHA BOUND BY IGF2BP2 111 59 All SZGR 2.0 genes in this pathway