Gene Page:SUSD5
Summary?
| GeneID | 26032 |
| Symbol | SUSD5 |
| Synonyms | - |
| Description | sushi domain containing 5 |
| Reference | HGNC:HGNC:29061|Ensembl:ENSG00000173705|Vega:OTTHUMG00000155829 |
| Gene type | protein-coding |
| Map location | 3p22.3 |
| Pascal p-value | 0.048 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| GSMA_I | Genome scan meta-analysis | Psr: 0.006 |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| KAT5 | 0.92 | 0.92 |
| DDX56 | 0.92 | 0.92 |
| INPP5K | 0.92 | 0.88 |
| YIPF3 | 0.92 | 0.91 |
| MRPS2 | 0.91 | 0.91 |
| ATG4B | 0.91 | 0.89 |
| TMUB2 | 0.91 | 0.88 |
| PSMD3 | 0.91 | 0.90 |
| RIC8A | 0.90 | 0.89 |
| PSMB2 | 0.90 | 0.87 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.8 | -0.80 | -0.80 |
| MT-CO2 | -0.80 | -0.77 |
| AF347015.31 | -0.78 | -0.77 |
| AF347015.27 | -0.78 | -0.79 |
| MT-CYB | -0.78 | -0.78 |
| AF347015.2 | -0.76 | -0.77 |
| AF347015.21 | -0.76 | -0.80 |
| AF347015.33 | -0.76 | -0.75 |
| AF347015.15 | -0.75 | -0.77 |
| AF347015.26 | -0.75 | -0.79 |
Section III. Gene Ontology annotation
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0005540 | 透明质酸结合 | IEA | - | |
| GO:0005488 | binding | IEA | - | |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0007155 | cell adhesion | IEA | - | |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0016020 | membrane | IEA | - | |
| GO:0016021 | integral to membrane | IEA | - |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| PAPASPYRIDONOS UNSTABLE ATEROSCLEROTIC PLAQUE DN | 43 | 29 | All SZGR 2.0 genes in this pathway |
| CONCANNON APOPTOSIS BY EPOXOMICIN UP | 239 | 157 | All SZGR 2.0 genes in this pathway |
| PEREZ TP53 TARGETS | 1174 | 695 | All SZGR 2.0 genes in this pathway |
| CERVERA SDHB TARGETS 1 UP | 118 | 66 | All SZGR 2.0 genes in this pathway |
| NOUZOVA METHYLATED IN APL | 68 | 39 | All SZGR 2.0 genes in this pathway |
| WANG SMARCE1 TARGETS DN | 371 | 218 | All SZGR 2.0 genes in this pathway |
| VICENT METASTASIS UP | 14 | 11 | All SZGR 2.0 genes in this pathway |
| SMID BREAST CANCER BASAL UP | 648 | 398 | All SZGR 2.0 genes in this pathway |
| BASSO HAIRY CELL LEUKEMIA DN | 80 | 66 | All SZGR 2.0 genes in this pathway |
| BOQUEST STEM CELL UP | 260 | 174 | All SZGR 2.0 genes in this pathway |
| TAYLOR METHYLATED IN ACUTE LYMPHOBLASTIC LEUKEMIA | 77 | 52 | All SZGR 2.0 genes in this pathway |
| YAUCH HEDGEHOG SIGNALING PARACRINE DN | 264 | 159 | All SZGR 2.0 genes in this pathway |