Gene Page:AMH

Summary?
GeneID 268
Symbol AMH
Synonyms MIF|MIS
Description anti-Mullerian hormone
Reference MIM:600957|HGNC:HGNC:464|Ensembl:ENSG00000104899|HPRD:02979|Vega:OTTHUMG00000180415
Gene type protein-coding
Map location 19p13.3
Pascal p-value 0.001
Fetal beta 0.047
eGene Anterior cingulate cortex BA24
Caudate basal ganglia
Cerebellar Hemisphere
Cerebellum
Cortex
Frontal Cortex BA9
Hippocampus
Nucleus accumbens basal ganglia
Putamen basal ganglia
元

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
PMID:cooccur High-throughput literature-search 系统搜索PubMed co-occu基因rring with SCZ keywords. A total of 3027 genes were included.
Literature High-throughput literature-search Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias Click to show details

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs733846 19 2241327 AMH ENSG00000104899.4 9.71884E-7 0 -7981 gtex_brain_ba24
rs2074861 19 2246652 AMH ENSG00000104899.4 8.91269E-7 0 -2656 gtex_brain_ba24
rs4807216 19 2248683 AMH ENSG00000104899.4 2.67364E-9 0 -625 gtex_brain_ba24
rs10407022 19 2249477 AMH ENSG00000104899.4 3.98178E-8 0 169 gtex_brain_ba24
rs733846 19 2241327 AMH ENSG00000104899.4 4.40212E-7 0.02 -7981 gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
GIT1 0.88 0.88
JPH3 0.87 0.89
RANGAP1 0.87 0.85
C17orf28 0.86 0.85
NICN1 0.86 0.84
OTUD5 0.86 0.83
PTPRN2 0.85 0.88
KATNB1 0.85 0.82
RNF123 0.85 0.83
PPP1R13B 0.85 0.86
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
AF347015.21 -0.69 -0.53
AF347015.31 -0.63 -0.49
MT-CO2 -0.63 -0.48
AF347015.2 -0.62 -0.45
AF347015.8 -0.60 -0.46
AF347015.18 -0.60 -0.45
AL139819.3 -0.59 -0.56
NOSTRIN -0.59 -0.45
GNG11 -0.58 -0.52
MT-CYB -0.58 -0.43

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION 267 161 All SZGR 2.0 genes in this pathway
KEGG TGF BETA SIGNALING PATHWAY 86 64 All SZGR 2.0 genes in this pathway
PID ALK2 PATHWAY 11 9 All SZGR 2.0 genes in this pathway
KIM WT1 TARGETS 12HR DN 209 122 All SZGR 2.0 genes in this pathway
NADERI BREAST CANCER PROGNOSIS UP 50 26 All SZGR 2.0 genes in this pathway
INGRAM SHH TARGETS UP 127 79 All SZGR 2.0 genes in this pathway
JIANG HYPOXIA NORMAL 311 205 All SZGR 2.0 genes in this pathway
BANDRES RESPONSE TO CARMUSTIN WITHOUT MGMT 48HR DN 32 25 All SZGR 2.0 genes in this pathway
BANDRES RESPONSE TO CARMUSTIN MGMT 48HR DN 161 105 All SZGR 2.0 genes in this pathway
BONOME OVARIAN CANCER SURVIVAL SUBOPTIMAL DEBULKING 510 309 All SZGR 2.0 genes in this pathway
MIKKELSEN ES ICP WITH H3K4ME3 718 401 All SZGR 2.0 genes in this pathway
NABA SECRETED FACTORS 344 197 All SZGR 2.0 genes in this pathway
NABA MATRISOME ASSOCIATED 753 411 All SZGR 2.0 genes in this pathway
NABA MATRISOME 1028 559 All SZGR 2.0 genes in this pathway