Gene Page:B9D1

Summary?
GeneID 27077
Symbol B9D1
Synonyms B9|EPPB9|MKS9|MKSR1
Description B9 protein domain 1
Reference MIM:614144|HGNC:HGNC:24123|Ensembl:ENSG00000108641|HPRD:16866|Vega:OTTHUMG00000059586
Gene type protein-coding
Map location 17p11.2
Pascal p-value 2.33E-5
Sherlock p-value 0.603
Fetal beta -1.612
DMG 1 (# studies)
eGene Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
DMG:Wockner_2014 Genome-wide DNA methylation analysis This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 3

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

Probe Chromosome Position Nearest gene P (dis) Beta (dis) FDR (dis) Study
cg11011774 17 19266179 B9D1 1.527E-4 -0.29 0.032 DMG:Wockner_2014
cg20272287 17 19247905 MIR1180;B9D1 2.576E-4 0.549 0.038 DMG:Wockner_2014
cg19157647 17 19247897 MIR1180;B9D1 3.988E-4 0.479 0.044 DMG:Wockner_2014

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs10025818 chr4 42364050 B9D1 27077 0.15 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception周),ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
SENP6 0.96 0.96
PCM1 0.95 0.97
ARID4B 0.95 0.96
AHCTF1 0.95 0.96
SR140 0.95 0.97
USP48 0.95 0.96
NOL8 0.94 0.96
SMEK1 0.94 0.96
TTC37 0.94 0.95
BRWD1 0.93 0.93
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
AF347015.31 -0.78 -0.86
MT-CO2 -0.77 -0.85
IFI27 -0.77 -0.86
FXYD1 -0.76 -0.84
HIGD1B -0.75 -0.86
ENHO -0.75 -0.88
AF347015.27 -0.74 -0.81
AF347015.33 -0.74 -0.80
AF347015.8 -0.72 -0.82
MT-CYB -0.72 -0.80

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
SENGUPTA NASOPHARYNGEAL CARCINOMA DN 349 157 All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA UP 1821 933 All SZGR 2.0 genes in this pathway
RODRIGUES THYROID CARCINOMA ANAPLASTIC DN 537 339 All SZGR 2.0 genes in this pathway
NIKOLSKY BREAST CANCER 17P11 AMPLICON 10 8 All SZGR 2.0 genes in this pathway
PAL PRMT5 TARGETS UP 203 135 All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 24HR DN 148 102 All SZGR 2.0 genes in this pathway
BURTON ADIPOGENESIS 8 86 57 All SZGR 2.0 genes in this pathway
SMID BREAST CANCER LUMINAL B UP 172 109 All SZGR 2.0 genes in this pathway
SMID BREAST CANCER BASAL DN 701 446 All SZGR 2.0 genes in this pathway
CAIRO HEPATOBLASTOMA CLASSES UP 605 377 All SZGR 2.0 genes in this pathway
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 13 172 107 All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 4HR DN 254 158 All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE EARLY LATE 317 190 All SZGR 2.0 genes in this pathway