Gene Page:APOBEC3C

Summary?
GeneID 27350
Symbol APOBEC3C
Synonyms A3C|APOBEC1L|ARDC2|ARDC4|ARP5|PBI|bK150C2.3
Description apolipoprotein B mRNA editing enzyme catalytic subunit 3C
Reference MIM:607750|HGNC:HGNC:17353|HPRD:09671|
Gene type protein-coding
Map location 22q13.1
Pascal p-value 0.398
Fetal beta 0.056
eGene Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene set Description Info
PMID:cooccur High-throughput literature-search 系统搜索PubMed基因co-occurring with SCZ keywords. A total of 3027 genes were included.
Literature High-throughput literature-search Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias Click to show details

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs138462 chr22 38905445 APOBEC3C 27350 0.04 cis
rs16999224 chr22 39076586 APOBEC3C 27350 0.04 cis
rs2716734 chr2 39947720 APOBEC3C 27350 0.02 trans
rs2716736 chr2 39947946 APOBEC3C 27350 0.02 trans
rs13024968 chr2 60026328 APOBEC3C 27350 0.02 trans
rs7430400 chr3 65885662 APOBEC3C 27350 0 trans
rs17023105 chr4 96074164 APOBEC3C 27350 2.101E-4 trans
rs10516959 chr4 96088848 APOBEC3C 27350 0.06 trans
rs7725925 chr5 8275608 APOBEC3C 27350 0.2 trans
rs996749 chr5 8307934 APOBEC3C 27350 0.15 trans
rs1587434 chr6 66615354 APOBEC3C 27350 0.17 trans
rs17165806 chr7 93469599 APOBEC3C 27350 0.03 trans
rs17165823 chr7 93476735 APOBEC3C 27350 0.02 trans
rs7777209 chr7 93485280 APOBEC3C 27350 0.03 trans
snp_a-2308001 0 APOBEC3C 27350 0.1 trans
rs2294031 chr8 1812077 APOBEC3C 27350 6.578E-4 trans
rs870686 chr8 25253521 APOBEC3C 27350 0.16 trans
rs10503771 chr8 25304019 APOBEC3C 27350 0.1 trans
rs12352894 chr9 38197383 APOBEC3C 27350 0.06 trans
rs12255258 chr10 106306927 APOBEC3C 27350 0.07 trans
rs740597 chr10 118508638 APOBEC3C 27350 0.1 trans
rs11025109 chr11 19405491 APOBEC3C 27350 0.11 trans
rs7110934 chr11 116127410 APOBEC3C 27350 0.01 trans
rs7941495 chr11 116129593 APOBEC3C 27350 0.04 trans
rs7928297 chr11 116129605 APOBEC3C 27350 0.04 trans
rs17121555 chr12 59241402 APOBEC3C 27350 0.01 trans
rs17121606 chr12 59258905 APOBEC3C 27350 0.01 trans
rs1684198 0 APOBEC3C 27350 0.02 trans
rs17075874 chr13 22671340 APOBEC3C 27350 0.09 trans
rs2764585 chr13 46880234 APOBEC3C 27350 0.02 trans
rs3742866 0 APOBEC3C 27350 0.18 trans
rs4792093 chr17 10939374 APOBEC3C 27350 0.07 trans
rs7223509 chr17 10940048 APOBEC3C 27350 0.07 trans
rs3786474 chr18 55135672 APOBEC3C 27350 0.17 trans
rs1343409 chrX 104143804 APOBEC3C 27350 0.07 trans
rs10521889 chrX 149836861 APOBEC3C 27350 0.03 trans
rs1882710 chrX 149894355 APOBEC3C 27350 0.18 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS DN 463 290 All SZGR 2.0 genes in this pathway
CASORELLI ACUTE PROMYELOCYTIC LEUKEMIA DN 663 425 All SZGR 2.0 genes in this pathway
DEURIG T CELL PROLYMPHOCYTIC LEUKEMIA DN 320 184 All SZGR 2.0 genes in this pathway
OSMAN BLADDER CANCER UP 404 246 All SZGR 2.0 genes in this pathway
PUJANA ATM PCC NETWORK 1442 892 All SZGR 2.0 genes in this pathway
BENNETT SYSTEMIC LUPUS ERYTHEMATOSUS 31 21 All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 16HR DN 86 62 All SZGR 2.0 genes in this pathway
CROMER TUMORIGENESIS UP 63 36 All SZGR 2.0 genes in this pathway
CROONQUIST IL6 DEPRIVATION DN 98 69 All SZGR 2.0 genes in this pathway
CROONQUIST NRAS SIGNALING DN 72 47 All SZGR 2.0 genes in this pathway
CROONQUIST NRAS VS STROMAL STIMULATION DN 99 65 All SZGR 2.0 genes in this pathway
KIM ALL DISORDERS CALB1 CORR DN 37 20 All SZGR 2.0 genes in this pathway
SMIRNOV RESPONSE TO IR 6HR UP 166 97 All SZGR 2.0 genes in this pathway