Summary
基因 2824
象征 gpm6b
Synonyms M6B
Description 糖蛋白M6b
Reference MIM:300051|HGNC:HGNC:4461|Ensembl:ENSG00000046653|HPRD:02082|Vega:Otthumg00000021162
基因类型 蛋白质编码
地图位置 Xp22.2
Sherlock p-value 0.002
DEG P值 DEG:Zhao_2015:p=5.77e-04:q=0.0926
胎儿β -1.133
支持 CELL ADHESION AND TRANSSYNAPTIC SIGNALING
潜在的突触基因

Gene in Data Sources
基因集名称 基因组方法 Description 信息
简历:PGCNP 全基因组协会研究 GWAS
DEG:Zhao_2015 RNA Sequencing analysis 转录组测序和全基因组的关联分析揭示了精神分裂症和躁郁症中的溶酶体功能和肌动蛋白细胞骨架重塑。
go_annotation 将与神经相关的关键字映射到基因本体论注释 与神经相关的关键字的命中:1

Section I. Genetics and epigenetics annotation


第二节。转录组注释

一般基因表达(GTEX)

无法使用

Devlopment期间的基因表达(BrainCloud)

Footnote:
共有269个时间点秘密策划,n = 38胎儿samples (x=1:38). Each triangle represents one time point.

时间变化的基因表达(brainspan)

Footnote:
SC:亚皮质区域;SM:感觉运动区域;FC:额叶皮层;和TP:颞顶皮层
ST1:胎儿(13-26个概念后周),ST2:婴儿早期至童年(4个月至11年)和ST3:青春期至成年期(13-23年)
所示的栏表示表达分布的较低25%和上层25%。

No co-expressed genes in brain regions


第三节。基因本体论注释

分子功能 去学期 证据 神经关键字 PubMed ID
去:0003674 Molecular_Function nd -
生物过程 去学期 证据 神经关键字 PubMed ID
去:0007399 nervous system development nas 神经突(GO期限:5) 8661015
去:0007275 multicellular organismal development IEA -
去:0030154 细胞分化 IEA -
Cellular component 去学期 证据 神经关键字 PubMed ID
去:0005634 nucleus 艾达 18029348
去:0005730 核仁 艾达 18029348
去:0016020 membrane IEA -
GO:0016021 膜不可或缺 nas -

Section V. Pathway annotation

路径名 路径大小 # SZGR 2.0 genes in pathway 信息
中村肿瘤区周围与中央 285 181 All SZGR 2.0 genes in this pathway
刘前列腺癌DN 481 290 All SZGR 2.0 genes in this pathway
Onken Uveal黑色素瘤 783 507 All SZGR 2.0 genes in this pathway
Davicioni pax foxo1手臂签名 59 38 All SZGR 2.0 genes in this pathway
DAVICIONI TARGETS OF PAX FOXO1 FUSIONS UP 255 177 All SZGR 2.0 genes in this pathway
DAVICIONI RHABDOMYOSARCOMA PAX FOXO1 FUSION UP 64 37 All SZGR 2.0 genes in this pathway
turashvili乳房导管癌与导管正常DN 198 110 All SZGR 2.0 genes in this pathway
turashvili乳房导管癌与小叶正常DN 69 43 All SZGR 2.0 genes in this pathway
turashvili乳房小叶癌与小叶正常 94 59 All SZGR 2.0 genes in this pathway
乳腺癌腔与基础DN 455 304 All SZGR 2.0 genes in this pathway
VECCHI GASTRIC CANCER EARLY DN 367 220 All SZGR 2.0 genes in this pathway
莱茵所有糖皮质激素治疗DN 362 238 All SZGR 2.0 genes in this pathway
Mullighan NPM1突变签名1 DN 126 86 All SZGR 2.0 genes in this pathway
Mullighan NPM1签名3 DN 162 116 All SZGR 2.0 genes in this pathway
剑麻结肠直肠腺瘤DN 291 176 All SZGR 2.0 genes in this pathway
甲状腺癌变性DN 537 339 All SZGR 2.0 genes in this pathway
chebotaev gr目标dn 120 73 All SZGR 2.0 genes in this pathway
Vanharanta子宫肌瘤 45 26 All SZGR 2.0 genes in this pathway
哈马凋亡通过Trail Up 584 356 All SZGR 2.0 genes in this pathway
KAN RESPONSE TO ARSENIC TRIOXIDE 123 80 All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER CLUSTER 2B 392 251 All SZGR 2.0 genes in this pathway
农民乳腺癌根源与基础 330 217 All SZGR 2.0 genes in this pathway
农民乳腺癌基础与仙女 330 215 All SZGR 2.0 genes in this pathway
MARTORIATI MDM4 TARGETS NEUROEPITHELIUM DN 164 111 All SZGR 2.0 genes in this pathway
留置权乳腺癌化生型与导管 83 51 All SZGR 2.0 genes in this pathway
CEBALLOS TARGETS OF TP53 AND MYC DN 38 31 All SZGR 2.0 genes in this pathway
YANG乳腺癌ESR1激光DN 50 38 All SZGR 2.0 genes in this pathway
Ingram SHH靶向DN 64 41 All SZGR 2.0 genes in this pathway
里克曼肿瘤分化了井和DN不良 382 224 All SZGR 2.0 genes in this pathway
Schaeffer前列腺开发48小时DN 428 306 All SZGR 2.0 genes in this pathway
Benporath ES 1 379 235 All SZGR 2.0 genes in this pathway
Benporath Suz12目标 1038 678 All SZGR 2.0 genes in this pathway
Benporath EED目标 1062 725 All SZGR 2.0 genes in this pathway
与H3K27me3的Benporath ES 1118 744 All SZGR 2.0 genes in this pathway
Benporath PRC2目标 652 441 All SZGR 2.0 genes in this pathway
Onder CDH1目标2 DN 464 276 All SZGR 2.0 genes in this pathway
HADDAD B淋巴细胞祖细胞 293 193 All SZGR 2.0 genes in this pathway
Zhan多发性骨髓瘤MF 47 27 All SZGR 2.0 genes in this pathway
NPM1突变DN的Verhaak AML 246 180 All SZGR 2.0 genes in this pathway
阿尔茨海默氏症疾病 1691 1088 All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 2 473 224 All SZGR 2.0 genes in this pathway
H3K27me3 196 93 All SZGR 2.0 genes in this pathway
海勒被甲基化沉默 282 183 All SZGR 2.0 genes in this pathway
Heller HDAC靶向DN 292 189 All SZGR 2.0 genes in this pathway
华莱士前列腺癌DN 6 6 All SZGR 2.0 genes in this pathway
骨骼DN中的Smid乳腺癌复发 315 197 All SZGR 2.0 genes in this pathway
SMID乳腺癌腔B DN 564 326 All SZGR 2.0 genes in this pathway
Smid乳腺癌基础 648 398 All SZGR 2.0 genes in this pathway
张乳腺癌祖细胞 425 253 All SZGR 2.0 genes in this pathway
西肾上腺皮质肿瘤DN 546 362 All SZGR 2.0 genes in this pathway
罗斯白血病与MLL融合 78 49 All SZGR 2.0 genes in this pathway
甜肺癌Kras DN 435 289 All SZGR 2.0 genes in this pathway
CHEN METABOLIC SYNDROM NETWORK 1210 725 All SZGR 2.0 genes in this pathway
croonquist nras发出信号 41 24 All SZGR 2.0 genes in this pathway
Yagi AML带8 21易位 368 247 All SZGR 2.0 genes in this pathway
YAGI AML WITH 11Q23 REARRANGED 351 238 All SZGR 2.0 genes in this pathway
korkola胚胎癌与精子瘤 22 15 All SZGR 2.0 genes in this pathway
由MYC DN监管 253 192 All SZGR 2.0 genes in this pathway
Nakayama软组织肿瘤PCA1 DN 74 47 All SZGR 2.0 genes in this pathway
Chicas RB1目标增长 243 155 All SZGR 2.0 genes in this pathway
Lee BMP2目标 745 475 All SZGR 2.0 genes in this pathway
Plasari TGFB1通过NFIC 10小时信号传导 54 38 All SZGR 2.0 genes in this pathway
Wang MLL目标 289 188 All SZGR 2.0 genes in this pathway
前列腺癌模型DN中的Acevedo FGFR1靶标 308 187 All SZGR 2.0 genes in this pathway

第六节。microRNA注释

mirna家族 目标位置 miRNA ID mirna seq
UTR开始 UTR结束 匹配方法
mir-124.1 757 764 1A,M8 HSA-MIR-124A UUAAGGCACGCGGUGAAUGCCA
mir-124/506 757 763 1a HSA-MIR-506 uaaggcacccuucugugaguaga
HSA-MIR-124brain UAAGGCACGCGGUGAAUGCC
miR-135 1115 1121 M8 HSA-MIR-135A UAUGGCUUUUUAUUCCUAUGUGA
HSA-MIR-135B Uauggcuuuucauuccuaugug
mir-141/200a 866 872 1a HSA-MIR-141 uaacacugucugugugugugaugg
hsa-miR-200a uaacacugucuguguguguaaacgaugu
HSA-MIR-141 uaacacugucugugugugugaugg
hsa-miR-200a uaacacugucuguguguguaaacgaugu
HSA-MIR-141 uaacacugucugugugugugaugg
hsa-miR-200a uaacacugucuguguguguaaacgaugu
miR-155 1728年 1735 1A,M8 HSA-MIR-155 uuaaugcuaaucgugauagggg
mir-186 176 182 1a HSA-MIR-186 caaagaauuuugggcuu
miR-194 1821年 1827年 1a HSA-MIR-194 uguaacagcaacuccauga
mir-217 64 70 1a hsa-miR-217 uacugcaucagaacugauuggau
mir-299-5p 896 902 1a hsa-miR-299-5p ugguuuaccgucccacauacau
mir-30-5p 926 932 1a HSA-MIR-30A-5P uguaaaacauccuccugagaag
hsa-miR-30cbrain UGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZ UGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZ uguaaacauccuaccucucagcu
hsa-miR-30e-5p UGUAAACAUCCUUGACUGGA
mir-376c 1287 1293 1a HSA-MIR-376C aacauagaggaaauuccacg
HSA-MIR-376C aacauagaggaaauuccacg
miR-384 146 153 1A,M8 HSA-MIR-384 auuccuagaaauuguucaua
miR-496 1720年 1726年 1a HSA-MIR-496 Auuacauggccaaucuc
mir-96 1790 1796 M8 HSA-MIR-96brain uuuggcacuagcacauuuuugc