Gene Page:PLA2G4D
Summary?
| GeneID | 283748 |
| Symbol | PLA2G4D |
| Synonyms | cPLA2delta |
| Description | phospholipase A2 group IVD |
| Reference | MIM:612864|HGNC:HGNC:30038|Ensembl:ENSG00000159337|HPRD:07145|Vega:OTTHUMG00000172587 |
| Gene type | protein-coding |
| Map location | 15q15.1 |
| Pascal p-value | 0.361 |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| PMID:cooccur | High-throughput literature-search | 体制matic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias | Click to show details |
Section I. Genetics and epigenetics annotation
eQTL annotation
eQTL annotation| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs10994209 | chr10 | 61877705 | PLA2G4D | 283748 | 0.04 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section III. Gene Ontology annotation
| Molecular function | 去的术语 | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0004623 | phospholipase A2 activity | IEA | - | |
| GO:0005509 | calcium ion binding | IEA | - | |
| GO:0016787 | hydrolase activity | IEA | - | |
| Biological process | 去的术语 | Evidence | Neuro keywords | PubMed ID |
| GO:0016042 | lipid catabolic process | IEA | - | |
| 去:0009395 | phospholipid catabolic process | IEA | - | |
| GO:0008152 | metabolic process | IEA | - | |
| Cellular component | 去的术语 | Evidence | Neuro keywords | PubMed ID |
| GO:0005737 | cytoplasm | IEA | - | |
| GO:0016020 | membrane | IEA | - | |
| GO:0031410 | cytoplasmic vesicle | IEA | - | |
| GO:0030659 | cytoplasmic vesicle membrane | IEA | - |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG FC GAMMA R MEDIATED PHAGOCYTOSIS | 97 | 71 | All SZGR 2.0 genes in this pathway |
| REACTOME ACYL CHAIN REMODELLING OF PI | 15 | 8 | All SZGR 2.0 genes in this pathway |
| REACTOME ACYL CHAIN REMODELLING OF PC | 22 | 13 | All SZGR 2.0 genes in this pathway |
| REACTOME PHOSPHOLIPID METABOLISM | 198 | 112 | All SZGR 2.0 genes in this pathway |
| REACTOME SYNTHESIS OF PA | 27 | 14 | All SZGR 2.0 genes in this pathway |
| REACTOME ACYL CHAIN REMODELLING OF PG | 16 | 8 | All SZGR 2.0 genes in this pathway |
| REACTOME ACYL CHAIN REMODELLING OF PE | 21 | 13 | All SZGR 2.0 genes in this pathway |
| REACTOME ACYL CHAIN REMODELLING OF PS | 15 | 7 | All SZGR 2.0 genes in this pathway |
| REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | 82 | 39 | All SZGR 2.0 genes in this pathway |
| REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS | 478 | 302 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS INTERMEDIATE PROGENITOR | 149 | 84 | All SZGR 2.0 genes in this pathway |