Gene Page:GUSB

Summary?
GeneID 2990
Symbol GUSB
Synonyms BG|MPS7
Description glucuronidase beta
Reference MIM:611499|HGNC:HGNC:4696|Ensembl:ENSG00000169919|HPRD:02018|Vega:OTTHUMG00000023735
Gene type protein-coding
Map location 7q21.11
Pascal p-value 0.815
Sherlock p-value 0.828
Fetal beta 0.908
eGene Myers' cis & trans
元

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
PMID:cooccur High-throughput literature-search 系统搜索PubMed co-occu基因rring with SCZ keywords. A total of 3027 genes were included.
Literature High-throughput literature-search Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias Click to show details

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs4718278 chr7 65243595 GUSB 2990 0.03 cis
rs1701760 chr7 65473687 GUSB 2990 0.03 cis
rs875971 chr7 65617594 GUSB 2990 0.14 cis
rs801193 chr7 66030611 GUSB 2990 0.06 cis
rs10258739 chr7 66062934 GUSB 2990 0.05 cis
rs2191268 chr7 66110223 GUSB 2990 0.01 cis
rs3853290 chr10 708359 GUSB 2990 0.18 trans
rs11253324 chr10 743835 GUSB 2990 0.18 trans
rs16955618 chr15 29937543 GUSB 2990 0.18 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
KEGG PENTOSE AND GLUCURONATE INTERCONVERSIONS 28 17 All SZGR 2.0 genes in this pathway
KEGG STARCH AND SUCROSE METABOLISM 52 33 All SZGR 2.0 genes in this pathway
KEGG GLYCOSAMINOGLYCAN DEGRADATION 21 14 All SZGR 2.0 genes in this pathway
KEGG PORPHYRIN AND CHLOROPHYLL METABOLISM 41 23 All SZGR 2.0 genes in this pathway
KEGG DRUG METABOLISM OTHER ENZYMES 51 27 All SZGR 2.0 genes in this pathway
KEGG LYSOSOME 121 83 All SZGR 2.0 genes in this pathway
REACTOME HS GAG DEGRADATION 20 15 All SZGR 2.0 genes in this pathway
REACTOME HYALURONAN UPTAKE AND DEGRADATION 10 7 All SZGR 2.0 genes in this pathway
REACTOME HYALURONAN METABOLISM 14 7 All SZGR 2.0 genes in this pathway
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM 52 33 All SZGR 2.0 genes in this pathway
REACTOME GLYCOSAMINOGLYCAN METABOLISM 111 69 All SZGR 2.0 genes in this pathway
REACTOME METABOLISM OF CARBOHYDRATES 247 154 All SZGR 2.0 genes in this pathway
NAKAMURA TUMOR ZONE PERIPHERAL VS CENTRAL DN 634 384 All SZGR 2.0 genes in this pathway
ONKEN UVEAL MELANOMA UP 783 507 All SZGR 2.0 genes in this pathway
ENK UV RESPONSE EPIDERMIS DN 508 354 All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN UP 1142 669 All SZGR 2.0 genes in this pathway
GRAESSMANN RESPONSE TO MC AND DOXORUBICIN UP 612 367 All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL BREAST 6 7WK UP 197 135 All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL TGFB1 TARGETS UP 169 127 All SZGR 2.0 genes in this pathway
SHETH LIVER CANCER VS TXNIP LOSS PAM1 229 137 All SZGR 2.0 genes in this pathway
TOMLINS PROSTATE CANCER UP 40 27 All SZGR 2.0 genes in this pathway
LOPEZ MBD TARGETS 957 597 All SZGR 2.0 genes in this pathway
PASQUALUCCI LYMPHOMA BY GC STAGE UP 283 177 All SZGR 2.0 genes in this pathway
ROSS AML WITH MLL FUSIONS 78 45 All SZGR 2.0 genes in this pathway
KLEIN PRIMARY EFFUSION LYMPHOMA UP 51 29 All SZGR 2.0 genes in this pathway
LIAN NEUTROPHIL GRANULE CONSTITUENTS 25 13 All SZGR 2.0 genes in this pathway
APPEL IMATINIB RESPONSE 33 22 All SZGR 2.0 genes in this pathway
KUMAR TARGETS OF MLL AF9 FUSION 405 264 All SZGR 2.0 genes in this pathway
PAL PRMT5 TARGETS UP 203 135 All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE UP 1691 1088 All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS INTERMEDIATE PROGENITOR 149 84 All SZGR 2.0 genes in this pathway
CHEN METABOLIC SYNDROM NETWORK 1210 725 All SZGR 2.0 genes in this pathway
HSIAO HOUSEKEEPING GENES 389 245 All SZGR 2.0 genes in this pathway
MILI PSEUDOPODIA HAPTOTAXIS DN 668 419 All SZGR 2.0 genes in this pathway
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 16 79 47 All SZGR 2.0 genes in this pathway
MARTENS BOUND BY PML RARA FUSION 456 287 All SZGR 2.0 genes in this pathway
CHICAS RB1 TARGETS SENESCENT 572 352 All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN 1972 1213 All SZGR 2.0 genes in this pathway
PURBEY TARGETS OF CTBP1 NOT SATB1 DN 448 282 All SZGR 2.0 genes in this pathway