Gene Page:HIST1H2AD
Summary?
| GeneID | 3013 |
| Symbol | HIST1H2AD |
| Synonyms | H2A.3|H2A/g|H2AFG |
| Description | histone cluster 1, H2ad |
| Reference | MIM:602792|HGNC: HGNC: 4729|HPRD:07534| |
| Gene type | protein-coding |
| Map location | 6p21.3 |
| Pascal p-value | 0.003 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| GSMA_I | Genome scan meta-analysis | Psr: 0.033 |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| UNG | 0.86 | 0.87 |
| HNRNPF | 0.86 | 0.77 |
| CLNS1A | 0.86 | 0.74 |
| PRPF38A | 0.84 | 0.79 |
| VIL2 | 0.84 | 0.82 |
| G3BP1 | 0.84 | 0.73 |
| ADH5 | 0.84 | 0.74 |
| ZNF20 | 0.84 | 0.78 |
| ST13 | 0.83 | 0.75 |
| GNAI3 | 0.83 | 0.79 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| C5orf53 | -0.56 | -0.58 |
| IFI27 | -0.53 | -0.61 |
| CA4 | -0.51 | -0.58 |
| AF347015.31 | -0.51 | -0.58 |
| AF347015.27 | -0.51 | -0.59 |
| CCNI2 | -0.51 | -0.58 |
| AF347015.21 | -0.51 | -0.61 |
| MT-CO2 | -0.50 | -0.59 |
| ASPHD1 | -0.50 | -0.54 |
| CXCL14 | -0.49 | -0.62 |
Section III. Gene Ontology annotation
| Molecular function | 去的术语 | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0003677 | DNA binding | NAS | - | |
| Biological process | 去的术语 | Evidence | Neuro keywords | PubMed ID |
| GO:0006334 | nucleosome assembly | NAS | - | |
| Cellular component | 去的术语 | Evidence | Neuro keywords | PubMed ID |
| GO:0000786 | nucleosome | NAS | - | |
| GO:0005634 | nucleus | IEA | - | |
| GO:0005694 | chromosome | IEA | - |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG SYSTEMIC LUPUS ERYTHEMATOSUS | 140 | 100 | All SZGR 2.0 genes in this pathway |
| REACTOME MEIOSIS | 116 | 81 | All SZGR 2.0 genes in this pathway |
| REACTOME CELL CYCLE | 421 | 253 | All SZGR 2.0 genes in this pathway |
| REACTOME RNA POL I TRANSCRIPTION | 89 | 64 | All SZGR 2.0 genes in this pathway |
| REACTOME TRANSCRIPTION | 210 | 127 | All SZGR 2.0 genes in this pathway |
| REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION | 122 | 80 | All SZGR 2.0 genes in this pathway |
| REACTOME CHROMOSOME MAINTENANCE | 122 | 80 | All SZGR 2.0 genes in this pathway |
| REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | 64 | 43 | All SZGR 2.0 genes in this pathway |
| REACTOME RNA POL I PROMOTER OPENING | 62 | 49 | All SZGR 2.0 genes in this pathway |
| REACTOME MEIOTIC RECOMBINATION | 86 | 62 | All SZGR 2.0 genes in this pathway |
| REACTOME MEIOTIC SYNAPSIS | 73 | 57 | All SZGR 2.0 genes in this pathway |
| REACTOME AMYLOIDS | 83 | 63 | All SZGR 2.0 genes in this pathway |
| REACTOME PACKAGING OF TELOMERE ENDS | 48 | 40 | All SZGR 2.0 genes in this pathway |
| REACTOME TELOMERE MAINTENANCE | 75 | 57 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY DOXORUBICIN DN | 1781 | 1082 | All SZGR 2.0 genes in this pathway |
| KONG E2F3 TARGETS | 97 | 58 | All SZGR 2.0 genes in this pathway |
| NUYTTEN NIPP1 TARGETS UP | 769 | 437 | All SZGR 2.0 genes in this pathway |
| LOPEZ MBD TARGETS | 957 | 597 | All SZGR 2.0 genes in this pathway |
| DAZARD RESPONSE TO UV NHEK UP | 244 | 151 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY FOXP3 STIMULATED | 1022 | 619 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY FOXP3 UNSTIMULATED | 1229 | 713 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY E2F4 UNSTIMULATED | 728 | 415 | All SZGR 2.0 genes in this pathway |
| WU ALZHEIMER DISEASE UP | 14 | 8 | All SZGR 2.0 genes in this pathway |
| DANG BOUND BY MYC | 1103 | 714 | All SZGR 2.0 genes in this pathway |
| FEVR CTNNB1 TARGETS DN | 553 | 343 | All SZGR 2.0 genes in this pathway |
| RAO BOUND BY SALL4 | 227 | 149 | All SZGR 2.0 genes in this pathway |