基因页：HLA-A

概括?
基因ID 3105
Symbol HLA-A
Synonyms AW-33 | AW-74 | HLAA
Description 主要的组织相容性复合物，I类，A
参考 MIM：142800|HGNC:HGNC:4931|Ensembl：ENSG00000206503|Ensembl:ENST00000376809|Ensembl:ENST00000454091|Ensembl:ENST00000456012|HPRD:00826|Vega：Otthumg00000130501
基因类型 protein-coding
Map location 6p21.3
Pascal P值 1E-12
Sherlock P值 0.382
胎儿β -1.353
eGene 前扣带回皮层BA24
尾状基底神经节
Cerebellar Hemisphere
小脑
皮质
Frontal Cortex BA9
海马
下丘脑
伏隔核基底神经节
梭子基底神经节
Myers' cis & trans
元

基因in Data Sources
基因集名称 Method of gene set Description 信息
CV:GWAScat 全基因组关联研究 This data set includes 560 SNPs associated with schizophrenia. A total of 486 genes were mapped to these SNPs within 50kb.
CV:GWASdb 全基因组关联研究 精神分裂症的GWASDB记录
简历：PGCNP Genome-wide Association Study GWAS
PMID:cooccur 高通量文献搜索 Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
GSMA_I Genome scan meta-analysis Psr: 0.033
文学 高通量文献搜索 与精神分裂症关键词共同存在：精神分裂症，精神分裂症，精神分裂症，精神分裂症 点击显示详细信息

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID 染色体 位置 eGene Gene Entrez ID pvalue qvalue TSS距离 eQTL type
RS3117143 chr6 29031141 HLA-A 3105 0.05 cis
rs3129788 chr6 29057638 HLA-A 3105 0.01 cis
RS3116830 chr6 29167574 HLA-A 3105 7.295E-4 cis
rs3117425 chr6 29260430 HLA-A 3105 7.295E-4 cis
RS6934993 chr6 29337499 HLA-A 3105 0.02 cis
rs3749971 chr6 29342774 HLA-A 3105 0.15 cis
RS406511 chr6 29376384 HLA-A 3105 4.3e-6 cis
rs2523443 chr6 29415463 HLA-A 3105 2.268e-5 cis
rs2746149 chr6 29435354 HLA-A 3105 1.009E-4 cis
RS1233487 chr6 29468808 HLA-A 3105 0.09 cis
RS1233396 chr6 29546798 HLA-A 3105 2.386E-5 cis
RS926552 chr6 29548088 HLA-A 3105 2.349E-4 cis
rs1233367 chr6 29622219 HLA-A 3105 0.11 cis
rs29228 chr6 29623738 HLA-A 3105 3.633e-7 cis
rs3129063 chr6 29645612 HLA-A 3105 1.6E-7 cis
RS387642 chr6 29645633 HLA-A 3105 6.597E-5 cis
RS3117295 chr6 29653376 HLA-A 3105 6.553E-5 cis
rs3129047 chr6 29670572 HLA-A 3105 0.07 cis
rs3129046 chr6 29670651 HLA-A 3105 3..959E-4 cis
rs2523405 chr6 29695304 HLA-A 3105 0.08 cis
rs2523404 chr6 29695712 HLA-A 3105 0.03 cis
rs1611350 chr6 29698820 HLA-A 3105 0.08 cis
RS2523399 chr6 29700078 HLA-A 3105 6.869E-5 cis
RS1610601 chr6 29700182 HLA-A 3105 1.392E-4 cis
rs1737077 chr6 29725294 HLA-A 3105 3.877E-4 cis
rs1737031 chr6 29737480 HLA-A 3105 0 cis
RS885940 chr6 29739056 HLA-A 3105 0 cis
RS1610637 chr6 29739905 HLA-A 3105 3..48E-4 cis
RS1615962 chr6 29745725 HLA-A 3105 3..48E-4 cis
rs1633030 chr6 29745793 HLA-A 3105 0.01 cis
rs1614309 chr6 29745883 HLA-A 3105 0.01 cis
RS1633002 chr6 29765046 HLA-A 3105 3..48E-4 cis
RS1632973 chr6 29777170 HLA-A 3105 3..48E-4 cis
RS1736963 chr6 29777982 HLA-A 3105 3..48E-4 cis
rs2523408 chr6 29778108 HLA-A 3105 0.03 cis
rs1077433 chr6 29783063 HLA-A 3105 3..48E-4 cis
RS2253981 chr6 29805921 HLA-A 3105 3..764E-4 cis
RS2254071 chr6 29806061 HLA-A 3105 3.466E-4 cis
rs2734990 chr6 29812504 HLA-A 3105 0.03 cis
RS2523766 chr6 29812833 HLA-A 3105 0.03 cis
rs9258555 chr6 29813015 HLA-A 3105 0.2 cis
RS2517869 chr6 29819324 HLA-A 3105 8.778e-13 cis
RS2508052 chr6 29820001 HLA-A 3105 3..046E-13 cis
rs2734970 chr6 29834471 HLA-A 3105 2.985E-11 cis
RS1611631 chr6 29835653 HLA-A 3105 0.12 cis
RS2571410 chr6 29881463 HLA-A 3105 0.05 cis
rs389600 chr6 29896998 HLA-A 3105 6.993E-13 cis
RS1655927 chr6 29899492 HLA-A 3105 2.57E-13 cis
RS2975046 chr6 29915148 HLA-A 3105 9.951E-4 cis
rs2735096 chr6 29915750 HLA-A 3105 1.428e-10 cis
RS1632882 chr6 29916367 HLA-A 3105 2.403E-9 cis
RS417162 chr6 29916504 HLA-A 3105 6.134E-19 cis
RS1655900 chr6 29916617 HLA-A 3105 1.901E-13 cis
RS1632879 chr6 29917702 HLA-A 3105 0.06 cis
RS1655906 chr6 29918253 HLA-A 3105 0.06 cis
RS2508037 chr6 29918435 HLA-A 3105 1.123E-17 cis
rs3115637 chr6 29918452 HLA-A 3105 0.01 cis
RS3094674 chr6 29918537 HLA-A 3105 0.08 cis
rs2905760 chr6 29926460 HLA-A 3105 0.05 cis
rs2517672 chr6 29937261 HLA-A 3105 0 cis
rs2523969 chr6 29938776 HLA-A 3105 0 cis
rs4947244 chr6 29954363 HLA-A 3105 0.07 cis
RS2275855 chr6 29976788 HLA-A 3105 0.05 cis
RS9357092 chr6 29984251 HLA-A 3105 0.04 cis
rs3115631 chr6 29986323 HLA-A 3105 1.029E-5 cis
rs259934 chr6 3.0006875 HLA-A 3105 2.08E-4 cis
rs259940 chr6 30011933 HLA-A 3105 4.085E-4 cis
rs1264703 chr6 3.0065415 HLA-A 3105 4.488E-7 cis
rs1264702 chr6 3.0065574 HLA-A 3105 2.784e-7 cis
rs2517595 chr6 30084548 HLA-A 3105 0.04 cis
RS9261471 chr6 30105348 HLA-A 3105 0.05 cis
RS2857435 chr6 3.0106023 HLA-A 3105 0.08 cis
RS2857439 chr6 30106295 HLA-A 3105 0.03 cis
RS9261485 chr6 3.0108750 HLA-A 3105 0.05 cis
RS9261488 chr6 30109411 HLA-A 3105 0.06 cis
RS9261489 chr6 30109481 HLA-A 3105 0.04 cis
RS9261491 chr6 30109860 HLA-A 3105 0.01 cis
rs757262 chr6 3.0114954 HLA-A 3105 0.05 cis
RS1573298 chr6 30116159 HLA-A 3105 0.04 cis
RS9261518 chr6 30116984 HLA-A 3105 0.08 cis
RS9261519 chr6 3.0117100 HLA-A 3105 0.03 cis
rs2517618 chr6 30158126 HLA-A 3105 0.12 cis
rs2844775 chr6 3.0179421 HLA-A 3105 0.04 cis
rs2844780 chr6 3.0204525 HLA-A 3105 0.01 cis
RS261946 chr6 3.0271333 HLA-A 3105 0.08 cis
rs3132649 chr6 30321056 HLA-A 3105 2.593E-4 cis
rs3094061 chr6 3.03.21188 HLA-A 3105 4.996E-4 cis
rs3130374 chr6 3.03.21335 HLA-A 3105 4.996E-4 cis
rs3130351 chr6 30328191 HLA-A 3105 3..818E-6 cis
rs3130352 chr6 3.03.28356 HLA-A 3105 1.417E-5 cis
rs3129818 chr6 3.03.42965 HLA-A 3105 0 cis
rs3132625 chr6 3.03.47719 HLA-A 3105 2.557E-6 cis
rs9404964 chr6 3.03.47832 HLA-A 3105 0.07 cis
rs3094050 chr6 3.03.58590 HLA-A 3105 1.047E-4 cis
RS3094703 chr6 3.03.58956 HLA-A 3105 2.73E-5 cis
rs3094035 chr6 3.03.63135 HLA-A 3105 9.62e-7 cis
rs3094034 chr6 30363350 HLA-A 3105 3..818E-6 cis
rs1034325 chr6 30368456 HLA-A 3105 0.04 cis
RS4713327 chr6 30383767 HLA-A 3105 0.01 cis
RS3094694 chr6 3.0451903 HLA-A 3105 0.01 cis
RS1075496 chr6 30658238 HLA-A 3105 0.04 cis
rs3132605 chr6 3.0739971 HLA-A 3105 0.03 cis
RS3131050 chr6 3.0760024 HLA-A 3105 0.03 cis
RS3131060 chr6 3.0763290 HLA-A 3105 0.05 cis
RS886424 chr6 3.0782001 HLA-A 3105 0.19 cis
rs3132581 chr6 3.0913457 HLA-A 3105 0.1 cis
rs3135309 chr6 28855804 HLA-A 3105 0.1 trans
RS3116830 chr6 29167574 HLA-A 3105 0.06 trans
rs3117425 chr6 29260430 HLA-A 3105 0.06 trans
RS406511 chr6 29376384 HLA-A 3105 7.367E-4 trans
rs2523443 chr6 29415463 HLA-A 3105 0 trans
rs2746149 chr6 29435354 HLA-A 3105 0.01 trans
RS1233396 chr6 29546798 HLA-A 3105 0 trans
RS926552 chr6 29548088 HLA-A 3105 0.02 trans
rs29228 chr6 29623738 HLA-A 3105 7.348E-5 trans
rs3129063 chr6 29645612 HLA-A 3105 3.478e-5 trans
RS387642 chr6 29645633 HLA-A 3105 0.01 trans
RS3117295 chr6 29653376 HLA-A 3105 0.01 trans
rs3129046 chr6 29670651 HLA-A 3105 0.03 trans
RS2523399 chr6 29700078 HLA-A 3105 0.01 trans
RS1610601 chr6 29700182 HLA-A 3105 0.01 trans
rs1737077 chr6 29725294 HLA-A 3105 0.03 trans
rs1737031 chr6 29737480 HLA-A 3105 0.13. trans
RS885940 chr6 29739056 HLA-A 3105 0.12 trans
RS1610637 chr6 29739905 HLA-A 3105 0.03 trans
RS1615962 chr6 29745725 HLA-A 3105 0.03 trans
RS1633002 chr6 29765046 HLA-A 3105 0.03 trans
RS1632973 chr6 29777170 HLA-A 3105 0.03 trans
RS1736963 chr6 29777982 HLA-A 3105 0.03 trans
rs9258466 0 HLA-A 3105 0.09 trans
rs1077433 chr6 29783063 HLA-A 3105 0.03 trans
RS2253981 chr6 29805921 HLA-A 3105 0.03 trans
RS2254071 chr6 29806061 HLA-A 3105 0.03 trans
rs407238 0 HLA-A 3105 9.808e-10 trans
RS2517869 chr6 29819324 HLA-A 3105 2.236E-10 trans
RS2508052 chr6 29820001 HLA-A 3105 7.32e-11 trans
SNP_A-2077850 0 HLA-A 3105 3..003E-11 trans
rs2734970 chr6 29834471 HLA-A 3105 7.877E-9 trans
rs9258865 0 HLA-A 3105 5.751e-11 trans
rs389600 chr6 29896998 HLA-A 3105 1.785e-10 trans
RS1655927 chr6 29899492 HLA-A 3105 6.17e-11 trans
RS2975046 chr6 29915148 HLA-A 3105 0.07 trans
rs2735096 chr6 29915750 HLA-A 3105 3.639E-8 trans
RS1632882 chr6 29916367 HLA-A 3105 5.84E-7 trans
RS417162 chr6 29916504 HLA-A 3105 8.576E-17 trans
RS1655900 chr6 29916617 HLA-A 3105 4.326E-11 trans
RS2508037 chr6 29918435 HLA-A 3105 2.578e-15 trans
rs2517672 chr6 29937261 HLA-A 3105 0.19 trans
rs2523969 chr6 29938776 HLA-A 3105 0.16 trans
rs3115631 chr6 29986323 HLA-A 3105 0 trans
rs259934 chr6 3.0006875 HLA-A 3105 0.02 trans
rs259940 chr6 30011933 HLA-A 3105 0.03 trans
rs1264703 chr6 3.0065415 HLA-A 3105 8.913E-5 trans
rs1264702 chr6 3.0065574 HLA-A 3105 5.714E-5 trans
rs3132649 chr6 30321056 HLA-A 3105 0.02 trans
rs3094061 chr6 3.03.21188 HLA-A 3105 0.04 trans
rs3130374 chr6 3.03.21335 HLA-A 3105 0.04 trans
rs3130351 chr6 30328191 HLA-A 3105 6.609E-4 trans
rs3130352 chr6 3.03.28356 HLA-A 3105 0 trans
rs3129818 chr6 3.03.42965 HLA-A 3105 0.13. trans
rs3132625 chr6 3.03.47719 HLA-A 3105 4.41E-4 trans
rs3094050 chr6 3.03.58590 HLA-A 3105 0.01 trans
RS3094703 chr6 3.03.58956 HLA-A 3105 0 trans
rs3094035 chr6 3.03.63135 HLA-A 3105 1.813E-4 trans
rs3094034 chr6 30363350 HLA-A 3105 6.609E-4 trans
RS3130544 chr6 31058339 HLA-A 3105 0.19 trans
RS2844559 chr6 31340074 HLA-A 3105 0.19 trans
RS16910024 chr9 25988971 HLA-A 3105 0.11 trans
rs9259874 6 29898105 HLA-A ENSG00000206503.7 1.598E-6 0.01 -10932 gtex_brain_ba24
rs9259896 6 29898559 HLA-A ENSG00000206503.7 1.866E-6 0.01 -10478 gtex_brain_ba24
rs1611320 6 29902373 HLA-A ENSG00000206503.7 1.774E-7 0.01 -6664 gtex_brain_ba24
rs1611329 6 29902875 HLA-A ENSG00000206503.7 2.713E-7 0.01 -6162 gtex_brain_ba24
rs435760 6 29902949 HLA-A ENSG00000206503.7 7.745e-7 0.01 -6088 gtex_brain_ba24
rs425482 6 29903217 HLA-A ENSG00000206503.7 1.899E-7 0.01 -5820 gtex_brain_ba24
RS543075878 6 29903389 HLA-A ENSG00000206503.7 4.76E-7 0.01 -5648 gtex_brain_ba24
rs567782341 6 29903577 HLA-A ENSG00000206503.7 1.843E-7 0.01 -5460 gtex_brain_ba24
rs545567928 6 29903675 HLA-A ENSG00000206503.7 1.706E-7 0.01 -5362 gtex_brain_ba24
RS9259976 6 29904131 HLA-A ENSG00000206503.7 8.61E-7 0.01 -4906 gtex_brain_ba24
RS9259978 6 29904180 HLA-A ENSG00000206503.7 8.265E-7 0.01 -4857 gtex_brain_ba24
RS9259981 6 29904357 HLA-A ENSG00000206503.7 2.431E-7 0.01 -4680 gtex_brain_ba24
RS9259982 6 29904389 HLA-A ENSG00000206503.7 8.86e-7 0.01 -4648 gtex_brain_ba24
rs2517736 6 29904505 HLA-A ENSG00000206503.7 1.615E-6 0.01 -4532 gtex_brain_ba24
rs2524000 6 29904528 HLA-A ENSG00000206503.7 1.624E-6 0.01 -4509 gtex_brain_ba24
rs400956 6 29905242 HLA-A ENSG00000206503.7 1.536E-6 0.01 -3795 gtex_brain_ba24
RS9259998 6 29905360 HLA-A ENSG00000206503.7 6.252E-7 0.01 -3677 gtex_brain_ba24
rs9260000 6 29905362 HLA-A ENSG00000206503.7 3.21E-7 0.01 -3675 gtex_brain_ba24
rs433128 6 29905566 HLA-A ENSG00000206503.7 1.157E-6 0.01 -3471 gtex_brain_ba24
rs2517731 6 29906049 HLA-A ENSG00000206503.7 6.37E-7 0.01 -2988 gtex_brain_ba24
rs428081 6 29906512 HLA-A ENSG00000206503.7 5.913E-7 0.01 -2525 gtex_brain_ba24
RS367077 6 29906564 HLA-A ENSG00000206503.7 6.178E-7 0.01 -2473 gtex_brain_ba24
RS414215 6 29906772 HLA-A ENSG00000206503.7 6.141E-7 0.01 -2265 gtex_brain_ba24
RS9260029 6 29907243 HLA-A ENSG00000206503.7 6.141E-7 0.01 -1794 gtex_brain_ba24
RS9260032 6 29907286 HLA-A ENSG00000206503.7 5.785e-7 0.01 -1751 gtex_brain_ba24
RS9260033 6 29907298 HLA-A ENSG00000206503.7 5.785e-7 0.01 -1739 gtex_brain_ba24
RS9260036 6 29907494 HLA-A ENSG00000206503.7 6.141E-7 0.01 -1543 gtex_brain_ba24
rs9260038 6 29907544 HLA-A ENSG00000206503.7 6.141E-7 0.01 -1493 gtex_brain_ba24
rs387850 6 29907696 HLA-A ENSG00000206503.7 6.141E-7 0.01 -1341 gtex_brain_ba24
rs366907 6 29907755 HLA-A ENSG00000206503.7 6.094E-7 0.01 -1282 gtex_brain_ba24
rs9260046 6 29908044 HLA-A ENSG00000206503.7 6.141E-7 0.01 -993 gtex_brain_ba24
RS199654615 6 29908396 HLA-A ENSG00000206503.7 2.989E-7 0.01 -641 gtex_brain_ba24
. 6 29908397 HLA-A ENSG00000206503.7 2.623E-7 0.01 -640 gtex_brain_ba24
RS9260063 6 29908544 HLA-A ENSG00000206503.7 5.127E-7 0.01 -493 gtex_brain_ba24
RS9260072 6 29908838 HLA-A ENSG00000206503.7 5.599E-7 0.01 -199 gtex_brain_ba24
RS9260077 6 29908954 HLA-A ENSG00000206503.7 5.139E-7 0.01 -83 gtex_brain_ba24
RS9260078 6 29909033 HLA-A ENSG00000206503.7 9.779E-7 0.01 -4 gtex_brain_ba24
RS9260081 6 29909153 HLA-A ENSG00000206503.7 5.203E-7 0.01 116 gtex_brain_ba24
RS9260087 6 29909376 HLA-A ENSG00000206503.7 6.563E-7 0.01 3.3.9 gtex_brain_ba24
RS9260094 6 29909472 HLA-A ENSG00000206503.7 5.621E-7 0.01 435 gtex_brain_ba24
RS9260096 6 29909510 HLA-A ENSG00000206503.7 2.326E-7 0.01 473 gtex_brain_ba24
RS9260103 6 29909593 HLA-A ENSG00000206503.7 6.227E-7 0.01 556 gtex_brain_ba24
RS9260104 6 29909616 HLA-A ENSG00000206503.7 6.227E-7 0.01 579 gtex_brain_ba24
RS9260107 6 29909745 HLA-A ENSG00000206503.7 6.317E-7 0.01 708 gtex_brain_ba24
RS9260111 6 29909916 HLA-A ENSG00000206503.7 6.333e-7 0.01 879 gtex_brain_ba24
RS9260112 6 29909918 HLA-A ENSG00000206503.7 6.333e-7 0.01 881 gtex_brain_ba24
RS9260115 6 29910027 HLA-A ENSG00000206503.7 6.522E-7 0.01 990 gtex_brain_ba24
RS9260118 6 29910176 HLA-A ENSG00000206503.7 6.522E-7 0.01 1139 gtex_brain_ba24
RS9260119 6 29910189 HLA-A ENSG00000206503.7 6.522E-7 0.01 1152 gtex_brain_ba24
RS9260125 6 29910457 HLA-A ENSG00000206503.7 1.22E-6 0.01 1420 gtex_brain_ba24
RS9260130 6 29910522 HLA-A ENSG00000206503.7 8.139E-7 0.01 1485 gtex_brain_ba24
rs1136695 6 29911064 HLA-A ENSG00000206503.7 6.253E-7 0.01 2027 gtex_brain_ba24
rs79222956 6 29911538 HLA-A ENSG00000206503.7 6.569E-7 0.01 2501 gtex_brain_ba24
RS1136903 6 29912280 HLA-A ENSG00000206503.7 1.101 e-6 0.01 3.243 gtex_brain_ba24
RS1141891 6 29912368 HLA-A ENSG00000206503.7 5.892E-7 0.01 3.3.3.1 gtex_brain_ba24
RS9260201 6 29912668 HLA-A ENSG00000206503.7 1.01E-6 0.01 3.631 gtex_brain_ba24
RS2975057 6 29913171 HLA-A ENSG00000206503.7 6.548E-7 0.01 4134 gtex_brain_ba24
rs9260223 6 29913944 HLA-A ENSG00000206503.7 6.513E-7 0.01 4907 gtex_brain_ba24
rs2523954 6 29914034 HLA-A ENSG00000206503.7 7.162E-7 0.01 4997 gtex_brain_ba24
RS2571383 6 29914315 HLA-A ENSG00000206503.7 6.522E-7 0.01 5278 gtex_brain_ba24
rs376646 6 29914377 HLA-A ENSG00000206503.7 6.591E-7 0.01 5340 gtex_brain_ba24
rs396379 6 29914500 HLA-A ENSG00000206503.7 6.522E-7 0.01 5463 gtex_brain_ba24
rs2524037 6 29914950 HLA-A ENSG00000206503.7 6.511E-7 0.01 5913 gtex_brain_ba24
rs2517723 6 29915268 HLA-A ENSG00000206503.7 2.132E-7 0.01 6231 gtex_brain_ba24
rs2517722 6 29915330 HLA-A ENSG00000206503.7 2.132E-7 0.01 6293 gtex_brain_ba24
RS417162 6 29916505 HLA-A ENSG00000206503.7 6.487E-7 0.01 7468 gtex_brain_ba24
rs9260316 6 29916914 HLA-A ENSG00000206503.7 5.714E-7 0.01 7877 gtex_brain_ba24
rs2517716 6 29917260 HLA-A ENSG00000206503.7 6.525E-7 0.01 8223 gtex_brain_ba24
rs2517713 6 29918099 HLA-A ENSG00000206503.7 6.522E-7 0.01 9062 gtex_brain_ba24
RS2508037 6 29918436 HLA-A ENSG00000206503.7 7.029E-7 0.01 9399 gtex_brain_ba24
rs2916806 6 29918684 HLA-A ENSG00000206503.7 6.522E-7 0.01 9647 gtex_brain_ba24
RS2975043 6 29918734 HLA-A ENSG00000206503.7 6.522E-7 0.01 9697 gtex_brain_ba24
rs2916807 6 29918770 HLA-A ENSG00000206503.7 6.522E-7 0.01 9733 gtex_brain_ba24
rs9260403 6 29918861 HLA-A ENSG00000206503.7 6.459E-7 0.01 9824 gtex_brain_ba24
rs9260408 6 29918917 HLA-A ENSG00000206503.7 1.137E-6 0.01 9880 gtex_brain_ba24
rs9260413 6 29919010 HLA-A ENSG00000206503.7 1.628E-7 0.01 9973 gtex_brain_ba24
rs9260424 6 29919098 HLA-A ENSG00000206503.7 5.854e-7 0.01 10061 gtex_brain_ba24
rs547275509 6 29919141 HLA-A ENSG00000206503.7 6.163E-7 0.01 10104 gtex_brain_ba24
rs2517709 6 29919421 HLA-A ENSG00000206503.7 6.075E-7 0.01 10384 gtex_brain_ba24
rs2517706 6 29919659 HLA-A ENSG00000206503.7 6.693E-7 0.01 10622 gtex_brain_ba24
rs9260463 6 29919862 HLA-A ENSG00000206503.7 6.453E-7 0.01 10825 gtex_brain_ba24
rs9260464 6 29919864 HLA-A ENSG00000206503.7 6.453E-7 0.01 10827 gtex_brain_ba24
rs9260483 6 29920238 HLA-A ENSG00000206503.7 6.48E-7 0.01 11201 gtex_brain_ba24
rs9260484 6 29920253 HLA-A ENSG00000206503.7 6.48E-7 0.01 11216 gtex_brain_ba24
rs9260486 6 29920281 HLA-A ENSG00000206503.7 6.396E-7 0.01 11244 gtex_brain_ba24
RS2975042 6 29920536 HLA-A ENSG00000206503.7 6.522E-7 0.01 11499 gtex_brain_ba24
rs2916809 6 29920549 HLA-A ENSG00000206503.7 6.522E-7 0.01 11512 gtex_brain_ba24
RS9260599 6 29922653 HLA-A ENSG00000206503.7 6.522E-7 0.01 13616 gtex_brain_ba24
rs2571390 6 29923554 HLA-A ENSG00000206503.7 1.443E-6 0.01 14517 gtex_brain_ba24
rs2844810 6 29923580 HLA-A ENSG00000206503.7 6.652E-7 0.01 14543 gtex_brain_ba24
RS1632984 6 29773392 HLA-A ENSG00000206503.7 1.676E-6 0 -135645 gtex_brain_putamen_basal
RS1632972 6 29777346 HLA-A ENSG00000206503.7 1.676E-6 0 -131691 gtex_brain_putamen_basal
RS1736965 6 29777443 HLA-A ENSG00000206503.7 1.676E-6 0 -131594 gtex_brain_putamen_basal
RS1632971 6 29777911 HLA-A ENSG00000206503.7 1.676E-6 0 -131126 gtex_brain_putamen_basal
RS1736962 6 29778613 HLA-A ENSG00000206503.7 1.676E-6 0 -130424 gtex_brain_putamen_basal
RS1736952 6 29785653 HLA-A ENSG00000206503.7 1.676E-6 0 -123384 gtex_brain_putamen_basal
rs2743931 6 29787072 HLA-A ENSG00000206503.7 1.676E-6 0 -121965 gtex_brain_putamen_basal
rs1633017 6 29788770 HLA-A ENSG00000206503.7 1.676E-6 0 -120267 gtex_brain_putamen_basal
rs1233334 6 29794897 HLA-A ENSG00000206503.7 3.001E-6 0 -114140 gtex_brain_putamen_basal
rs56388903 6 29795720 HLA-A ENSG00000206503.7 2.117E-6 0 -113317 gtex_brain_putamen_basal
rs1707 6 29798610 HLA-A ENSG00000206503.7 2.406E-6 0 -110427 gtex_brain_putamen_basal
rs1233330 6 29799103 HLA-A ENSG00000206503.7 2.117E-6 0 -109934 gtex_brain_putamen_basal
rs394146 6 29799235 HLA-A ENSG00000206503.7 1.738E-6 0 -109802 gtex_brain_putamen_basal
RS1234836 6 29801035 HLA-A ENSG00000206503.7 1.676E-6 0 -108002 gtex_brain_putamen_basal
rs1233326 6 29804071 HLA-A ENSG00000206503.7 1.676E-6 0 -104966 gtex_brain_putamen_basal
rs1233324 6 29806107 HLA-A ENSG00000206503.7 1.676E-6 0 -102930 gtex_brain_putamen_basal
RS3094644 6 29812578 HLA-A ENSG00000206503.7 1.898E-6 0 -96459 gtex_brain_putamen_basal
RS3132727 6 29813363 HLA-A ENSG00000206503.7 1.676E-6 0 -95674 gtex_brain_putamen_basal
rs3128912 6 29815637 HLA-A ENSG00000206503.7 1.676E-6 0 -93400 gtex_brain_putamen_basal
rs3115629 6 29815713 HLA-A ENSG00000206503.7 1.676E-6 0 -93324 gtex_brain_putamen_basal
rs3128911 6 29818030 HLA-A ENSG00000206503.7 1.676E-6 0 -91007年 gtex_brain_putamen_basal
rs3128908 6 29824267 HLA-A ENSG00000206503.7 2.261E-6 0 -84770 gtex_brain_putamen_basal
RS9258693 6 29824534 HLA-A ENSG00000206503.7 1.959E-6 0 -84503 gtex_brain_putamen_basal
RS9258694 6 29824537 HLA-A ENSG00000206503.7 1.959E-6 0 -84500 gtex_brain_putamen_basal
rs3128907 6 29824994 HLA-A ENSG00000206503.7 1.676E-6 0 -84043 gtex_brain_putamen_basal
RS3094172 6 29828019 HLA-A ENSG00000206503.7 1.676E-6 0 -81018 gtex_brain_putamen_basal
RS3094170 6 29829265 HLA-A ENSG00000206503.7 1.676E-6 0 -79772 gtex_brain_putamen_basal
RS3094656 6 29830751 HLA-A ENSG00000206503.7 2.117E-6 0 -78286 gtex_brain_putamen_basal
rs3128904 6 29831466 HLA-A ENSG00000206503.7 2.117E-6 0 -77571 gtex_brain_putamen_basal
RS3094168 6 29831577 HLA-A ENSG00000206503.7 1.676E-6 0 -77460 gtex_brain_putamen_basal
rs3128902 6 29832514 HLA-A ENSG00000206503.7 1.676E-6 0 -76523 gtex_brain_putamen_basal
rs3128901 6 29832907 HLA-A ENSG00000206503.7 1.676E-6 0 -76130 gtex_brain_putamen_basal
rs2734976 6 29832958 HLA-A ENSG00000206503.7 3..03E-6 0 -76079 gtex_brain_putamen_basal
RS3094166 6 29833102 HLA-A ENSG00000206503.7 1.676E-6 0 -75935 gtex_brain_putamen_basal
rs9258859 6 29836090 HLA-A ENSG00000206503.7 1.682E-6 0 -72947 gtex_brain_putamen_basal
rs3094157 6 29836239 HLA-A ENSG00000206503.7 1.676E-6 0 -72798 gtex_brain_putamen_basal
rs3128888 6 29841356 HLA-A ENSG00000206503.7 1.676E-6 0 -67681 gtex_brain_putamen_basal
RS1611581 6 29850827 HLA-A ENSG00000206503.7 5.433e-7 0 -58210 gtex_brain_putamen_basal
rs3115612 6 29851443 HLA-A ENSG00000206503.7 3.165e-6 0 -57594 gtex_brain_putamen_basal
RS3094645 6 29853936 HLA-A ENSG00000206503.7 1.991E-6 0 -55101 gtex_brain_putamen_basal
rs9259329 6 29861134 HLA-A ENSG00000206503.7 1.101 e-6 0 -47903 gtex_brain_putamen_basal
rs1611440 6 29880429 HLA-A ENSG00000206503.7 1.72E-6 0 -28608 gtex_brain_putamen_basal
rs6926454 6 29897872 HLA-A ENSG00000206503.7 2.547E-6 0 -11165 gtex_brain_putamen_basal
rs9259871 6 29897974 HLA-A ENSG00000206503.7 2.462E-6 0 -11063 gtex_brain_putamen_basal
rs9259874 6 29898105 HLA-A ENSG00000206503.7 2.78E-6 0 -10932 gtex_brain_putamen_basal
rs9259896 6 29898559 HLA-A ENSG00000206503.7 2.697E-6 0 -10478 gtex_brain_putamen_basal
rs2517741 6 29898806 HLA-A ENSG00000206503.7 2.372E-6 0 -10231 gtex_brain_putamen_basal
rs2517740 6 29898821 HLA-A ENSG00000206503.7 2.369E-6 0 -10216 gtex_brain_putamen_basal
rs1611320 6 29902373 HLA-A ENSG00000206503.7 1.318E-7 0 -6664 gtex_brain_putamen_basal
rs1611329 6 29902875 HLA-A ENSG00000206503.7 3..647E-7 0 -6162 gtex_brain_putamen_basal
rs435760 6 29902949 HLA-A ENSG00000206503.7 1.197E-7 0 -6088 gtex_brain_putamen_basal
RS543075878 6 29903389 HLA-A ENSG00000206503.7 1.191E-6 0 -5648 gtex_brain_putamen_basal
rs567782341 6 29903577 HLA-A ENSG00000206503.7 3..415E-7 0 -5460 gtex_brain_putamen_basal
rs545567928 6 29903675 HLA-A ENSG00000206503.7 2.114E-7 0 -5362 gtex_brain_putamen_basal
RS9259976 6 29904131 HLA-A ENSG00000206503.7 6.655E-8 0 -4906 gtex_brain_putamen_basal
RS9259978 6 29904180 HLA-A ENSG00000206503.7 7.484E-8 0 -4857 gtex_brain_putamen_basal
RS9259981 6 29904357 HLA-A ENSG00000206503.7 1.424E-7 0 -4680 gtex_brain_putamen_basal
RS9259982 6 29904389 HLA-A ENSG00000206503.7 6.564e-8 0 -4648 gtex_brain_putamen_basal
rs2517736 6 29904505 HLA-A ENSG00000206503.7 3.324e-8 0 -4532 gtex_brain_putamen_basal
rs2524000 6 29904528 HLA-A ENSG00000206503.7 2.957E-8 0 -4509 gtex_brain_putamen_basal
rs2523998 6 29904865 HLA-A ENSG00000206503.7 2.634E-6 0 -4172 gtex_brain_putamen_basal
rs2916815 6 29905015 HLA-A ENSG00000206503.7 2.325E-6 0 -4022 gtex_brain_putamen_basal
RS9259991 6 29905101 HLA-A ENSG00000206503.7 4.334E-8 0 -3936 gtex_brain_putamen_basal
RS9259992 6 29905121 HLA-A ENSG00000206503.7 2.035E-8 0 -3916 gtex_brain_putamen_basal
rs400956 6 29905242 HLA-A ENSG00000206503.7 1.014E-8 0 -3795 gtex_brain_putamen_basal
RS9259998 6 29905360 HLA-A ENSG00000206503.7 6.227E-8 0 -3677 gtex_brain_putamen_basal
rs9260000 6 29905362 HLA-A ENSG00000206503.7 1.41E-7 0 -3675 gtex_brain_putamen_basal
RS201291609 6 29905512 HLA-A ENSG00000206503.7 7.75e-8 0 -3525 gtex_brain_putamen_basal
rs433128 6 29905566 HLA-A ENSG00000206503.7 3..932E-8 0 -3471 gtex_brain_putamen_basal
rs9260010 6 29905804 HLA-A ENSG00000206503.7 1.514E-7 0 -3233 gtex_brain_putamen_basal
rs2517731 6 29906049 HLA-A ENSG00000206503.7 1.712E-8 0 -2988 gtex_brain_putamen_basal
rs428081 6 29906512 HLA-A ENSG00000206503.7 1.864E-8 0 -2525 gtex_brain_putamen_basal
RS367077 6 29906564 HLA-A ENSG00000206503.7 1.044E-8 0 -2473 gtex_brain_putamen_basal
RS2860580 6 29906691 HLA-A ENSG00000206503.7 5.081E-7 0 -2346 gtex_brain_putamen_basal
RS414215 6 29906772 HLA-A ENSG00000206503.7 1.768E-8 0 -2265 gtex_brain_putamen_basal
RS9260029 6 29907243 HLA-A ENSG00000206503.7 2.083E-8 0 -1794 gtex_brain_putamen_basal
RS9260032 6 29907286 HLA-A ENSG00000206503.7 3..668E-8 0 -1751 gtex_brain_putamen_basal
RS9260033 6 29907298 HLA-A ENSG00000206503.7 3.689E-8 0 -1739 gtex_brain_putamen_basal
RS9260036 6 29907494 HLA-A ENSG00000206503.7 2.312E-8 0 -1543 gtex_brain_putamen_basal
rs9260038 6 29907544 HLA-A ENSG00000206503.7 2.356E-8 0 -1493 gtex_brain_putamen_basal
rs387850 6 29907696 HLA-A ENSG00000206503.7 2.515E-8 0 -1341 gtex_brain_putamen_basal
rs366907 6 29907755 HLA-A ENSG00000206503.7 2.508E-8 0 -1282 gtex_brain_putamen_basal
rs1614003 6 29907996 HLA-A ENSG00000206503.7 3..874E-7 0 -1041年 gtex_brain_putamen_basal
rs9260046 6 29908044 HLA-A ENSG00000206503.7 2.93E-8 0 -993 gtex_brain_putamen_basal
RS199654615 6 29908396 HLA-A ENSG00000206503.7 5.475E-8 0 -641 gtex_brain_putamen_basal
. 6 29908397 HLA-A ENSG00000206503.7 7.614E-8 0 -640 gtex_brain_putamen_basal
RS9260063 6 29908544 HLA-A ENSG00000206503.7 2.862e-8 0 -493 gtex_brain_putamen_basal
RS9260072 6 29908838 HLA-A ENSG00000206503.7 3.807E-8 0 -199 gtex_brain_putamen_basal
RS9260077 6 29908954 HLA-A ENSG00000206503.7 2.377E-8 0 -83 gtex_brain_putamen_basal
RS9260078 6 29909033 HLA-A ENSG00000206503.7 1.895E-6 0 -4 gtex_brain_putamen_basal
RS9260081 6 29909153 HLA-A ENSG00000206503.7 2.691E-8 0 116 gtex_brain_putamen_basal
RS1632889 6 29909181 HLA-A ENSG00000206503.7 3.226e-7 0 144 gtex_brain_putamen_basal
RS1655919 6 29909197 HLA-A ENSG00000206503.7 1.677E-6 0 160 gtex_brain_putamen_basal
RS9260087 6 29909376 HLA-A ENSG00000206503.7 1.947E-8 0 3.3.9 gtex_brain_putamen_basal
RS9260094 6 29909472 HLA-A ENSG00000206503.7 1.241E-8 0 435 gtex_brain_putamen_basal
RS9260096 6 29909510 HLA-A ENSG00000206503.7 4.713E-8 0 473 gtex_brain_putamen_basal
RS9260098 6 29909523 HLA-A ENSG00000206503.7 1.496E-6 0 486 gtex_brain_putamen_basal
RS9260103 6 29909593 HLA-A ENSG00000206503.7 5.132E-8 0 556 gtex_brain_putamen_basal
RS9260104 6 29909616 HLA-A ENSG00000206503.7 5.184e-8 0 579 gtex_brain_putamen_basal
RS9260107 6 29909745 HLA-A ENSG00000206503.7 4.966E-8 0 708 gtex_brain_putamen_basal
RS9260111 6 29909916 HLA-A ENSG00000206503.7 7.552E-8 0 879 gtex_brain_putamen_basal
RS9260112 6 29909918 HLA-A ENSG00000206503.7 7.566e-8 0 881 gtex_brain_putamen_basal
RS9260114 6 29909988 HLA-A ENSG00000206503.7 1.656E-7 0 951 gtex_brain_putamen_basal
RS9260115 6 29910027 HLA-A ENSG00000206503.7 3.998E-8 0 990 gtex_brain_putamen_basal
rs3132688 6 29910083 HLA-A ENSG00000206503.7 1.755E-6 0 1046 gtex_brain_putamen_basal
RS9260118 6 29910176 HLA-A ENSG00000206503.7 4.251E-8 0 1139 gtex_brain_putamen_basal
RS9260119 6 29910189 HLA-A ENSG00000206503.7 4.251E-8 0 1152 gtex_brain_putamen_basal
rs2916801 6 29910286 HLA-A ENSG00000206503.7 3..545E-7 0 1249 gtex_brain_putamen_basal
RS9260125 6 29910457 HLA-A ENSG00000206503.7 2.319E-7 0 1420 gtex_brain_putamen_basal
RS9260127 6 29910478 HLA-A ENSG00000206503.7 9.043e-7 0 1441 gtex_brain_putamen_basal
RS9260129 6 29910508 HLA-A ENSG00000206503.7 1.238E-7 0 1471 gtex_brain_putamen_basal
RS9260130 6 29910522 HLA-A ENSG00000206503.7 5.66E-8 0 1485 gtex_brain_putamen_basal
rs1136695 6 29911064 HLA-A ENSG00000206503.7 5.282E-8 0 2027 gtex_brain_putamen_basal
rs1059542 6 29911256 HLA-A ENSG00000206503.7 1.502 e-6 0 2219 gtex_brain_putamen_basal
rs67054159 6 29911457 HLA-A ENSG00000206503.7 1.733E-6 0 2420 gtex_brain_putamen_basal
rs79222956 6 29911538 HLA-A ENSG00000206503.7 4.12E-8 0 2501 gtex_brain_putamen_basal
RS1136903 6 29912280 HLA-A ENSG00000206503.7 3.82e-8 0 3.243 gtex_brain_putamen_basal
RS1141891 6 29912368 HLA-A ENSG00000206503.7 3.34e-8 0 3.3.3.1 gtex_brain_putamen_basal
rs1655895 6 29912517 HLA-A ENSG00000206503.7 1.777E-6 0 3480 gtex_brain_putamen_basal
RS9260201 6 29912668 HLA-A ENSG00000206503.7 4.852E-8 0 3.631 gtex_brain_putamen_basal
rs2571381 6 29912830 HLA-A ENSG00000206503.7 3.454e-7 0 3.793 gtex_brain_putamen_basal
rs1137296 6 29912852 HLA-A ENSG00000206503.7 2.198E-8 0 3.815 gtex_brain_putamen_basal
RS14288 6 29913042 HLA-A ENSG00000206503.7 2.198E-6 0 4005 gtex_brain_putamen_basal
RS9260205 6 29913074 HLA-A ENSG00000206503.7 4.652E-7 0 4037 gtex_brain_putamen_basal
RS41546815 6 29913078 HLA-A ENSG00000206503.7 4.652E-7 0 4041 gtex_brain_putamen_basal
RS2975057 6 29913171 HLA-A ENSG00000206503.7 4.182E-8 0 4134 gtex_brain_putamen_basal
rs2499 6 29913542 HLA-A ENSG00000206503.7 1.676E-6 0 4505 gtex_brain_putamen_basal
RS13488 6 29913638 HLA-A ENSG00000206503.7 3..332E-7 0 4601 gtex_brain_putamen_basal
rs2248006 6 29913672 HLA-A ENSG00000206503.7 3.476E-7 0 4635 gtex_brain_putamen_basal
rs2571382 6 29913727 HLA-A ENSG00000206503.7 3..315E-7 0 4690 gtex_brain_putamen_basal
rs9260223 6 29913944 HLA-A ENSG00000206503.7 4.232E-8 0 4907 gtex_brain_putamen_basal
rs2523954 6 29914034 HLA-A ENSG00000206503.7 4.014E-8 0 4997 gtex_brain_putamen_basal
rs1616549 6 29914270 HLA-A ENSG00000206503.7 1.676E-6 0 5233 gtex_brain_putamen_basal
RS2571383 6 29914315 HLA-A ENSG00000206503.7 4.251E-8 0 5278 gtex_brain_putamen_basal
rs376646 6 29914377 HLA-A ENSG00000206503.7 4.196E-8 0 5340 gtex_brain_putamen_basal
rs396379 6 29914500 HLA-A ENSG00000206503.7 4.251E-8 0 5463 gtex_brain_putamen_basal
rs2524037 6 29914950 HLA-A ENSG00000206503.7 4.291E-8 0 5913 gtex_brain_putamen_basal
RS2248162 6 29915061 HLA-A ENSG00000206503.7 7.914E-8 0 6024 gtex_brain_putamen_basal
RS2571386 6 29915122 HLA-A ENSG00000206503.7 1.676E-6 0 6085 gtex_brain_putamen_basal
rs2517723 6 29915268 HLA-A ENSG00000206503.7 3.514e-8 0 6231 gtex_brain_putamen_basal
rs2517722 6 29915330 HLA-A ENSG00000206503.7 3..525E-8 0 6293 gtex_brain_putamen_basal
RS417162 6 29916505 HLA-A ENSG00000206503.7 4.343E-8 0 7468 gtex_brain_putamen_basal
RS1655902 6 29916855 HLA-A ENSG00000206503.7 7.023E-7 0 7818 gtex_brain_putamen_basal
rs9260316 6 29916914 HLA-A ENSG00000206503.7 6.053 e-8 0 7877 gtex_brain_putamen_basal
RS1655903 6 29917005 HLA-A ENSG00000206503.7 2.493E-6 0 7968 gtex_brain_putamen_basal
RS1655904 6 29917146 HLA-A ENSG00000206503.7 1.888E-6 0 8109 gtex_brain_putamen_basal
rs2517716 6 29917260 HLA-A ENSG00000206503.7 4.845E-8 0 8223 gtex_brain_putamen_basal
RS1632880 6 29917610 HLA-A ENSG00000206503.7 3..545E-7 0 8573 gtex_brain_putamen_basal
RS1632879 6 29917703 HLA-A ENSG00000206503.7 3..545E-7 0 8666 gtex_brain_putamen_basal
rs2517713 6 29918099 HLA-A ENSG00000206503.7 4.251E-8 0 9062 gtex_brain_putamen_basal
RS1655906 6 29918254 HLA-A ENSG00000206503.7 2.3E-6 0 9217 gtex_brain_putamen_basal
RS2508037 6 29918436 HLA-A ENSG00000206503.7 4.258e-8 0 9399 gtex_brain_putamen_basal
RS1655907 6 29918587 HLA-A ENSG00000206503.7 2.3E-6 0 9550 gtex_brain_putamen_basal
RS1655908 6 29918616 HLA-A ENSG00000206503.7 2.703E-6 0 9579 gtex_brain_putamen_basal
RS1632876 6 29918619 HLA-A ENSG00000206503.7 2.703E-6 0 9582 gtex_brain_putamen_basal
rs2916806 6 29918684 HLA-A ENSG00000206503.7 4.246E-8 0 9647 gtex_brain_putamen_basal
RS2975043 6 29918734 HLA-A ENSG00000206503.7 4.251E-8 0 9697 gtex_brain_putamen_basal
rs2916807 6 29918770 HLA-A ENSG00000206503.7 4.251E-8 0 9733 gtex_brain_putamen_basal
rs9260403 6 29918861 HLA-A ENSG00000206503.7 4.26E-8 0 9824 gtex_brain_putamen_basal
rs9260408 6 29918917 HLA-A ENSG00000206503.7 4.791E-7 0 9880 gtex_brain_putamen_basal
rs9260413 6 29919010 HLA-A ENSG00000206503.7 4.812E-8 0 9973 gtex_brain_putamen_basal
rs9260414 6 29919020 HLA-A ENSG00000206503.7 1.495E-7 0 9983 gtex_brain_putamen_basal
rs9260424 6 29919098 HLA-A ENSG00000206503.7 4.1E-8 0 10061 gtex_brain_putamen_basal
rs547275509 6 29919141 HLA-A ENSG00000206503.7 4.324e-8 0 10104 gtex_brain_putamen_basal
rs2517709 6 29919421 HLA-A ENSG00000206503.7 4.833E-8 0 10384 gtex_brain_putamen_basal
rs2517706 6 29919659 HLA-A ENSG00000206503.7 4.778E-8 0 10622 gtex_brain_putamen_basal
RS7747114 6 29919774 HLA-A ENSG00000206503.7 5.884E-8 0 10737 gtex_brain_putamen_basal
RS7747253 6 29919779 HLA-A ENSG00000206503.7 6.853E-7 0 10742 gtex_brain_putamen_basal
rs9260463 6 29919862 HLA-A ENSG00000206503.7 4.281E-8 0 10825 gtex_brain_putamen_basal
rs9260464 6 29919864 HLA-A ENSG00000206503.7 4.281E-8 0 10827 gtex_brain_putamen_basal
rs9260468 6 29920000 HLA-A ENSG00000206503.7 6.748E-8 0 10963 gtex_brain_putamen_basal
RS1655910 6 29920105 HLA-A ENSG00000206503.7 7.504e-8 0 11068 gtex_brain_putamen_basal
rs9260483 6 29920238 HLA-A ENSG00000206503.7 1.403E-7 0 11201 gtex_brain_putamen_basal
rs9260484 6 29920253 HLA-A ENSG00000206503.7 1.403E-7 0 11216 gtex_brain_putamen_basal
rs9260486 6 29920281 HLA-A ENSG00000206503.7 1.393E-7 0 11244 gtex_brain_putamen_basal
RS554052992 6 29920465 HLA-A ENSG00000206503.7 5.969E-7 0 11428 gtex_brain_putamen_basal
RS2975042 6 29920536 HLA-A ENSG00000206503.7 4.251E-8 0 11499 gtex_brain_putamen_basal
rs2916809 6 29920549 HLA-A ENSG00000206503.7 4.251E-8 0 11512 gtex_brain_putamen_basal
rs576595600 6 29920841 HLA-A ENSG00000206503.7 8.186E-9 0 11804 gtex_brain_putamen_basal
RS9260512 6 29920883 HLA-A ENSG00000206503.7 3.02E-8 0 11846 gtex_brain_putamen_basal
RS9260521 6 29921135 HLA-A ENSG00000206503.7 3.105E-8 0 12098 gtex_brain_putamen_basal
RS9260524 6 29921158 HLA-A ENSG00000206503.7 3..111E-8 0 12121 gtex_brain_putamen_basal
RS9260530 6 29921220 HLA-A ENSG00000206503.7 1.24E-8 0 12183 gtex_brain_putamen_basal
rs2735092 6 29921262 HLA-A ENSG00000206503.7 8.157E-9 0 12225 gtex_brain_putamen_basal
RS111867975 6 29921542 HLA-A ENSG00000206503.7 4.468E-8 0 12505 gtex_brain_putamen_basal
RS9260555 6 29921773 HLA-A ENSG00000206503.7 2.504E-8 0 12736 gtex_brain_putamen_basal
RS9260559 6 29921822 HLA-A ENSG00000206503.7 2.334e-8 0 12785 gtex_brain_putamen_basal
RS9260565 6 29921880 HLA-A ENSG00000206503.7 2.466E-8 0 12843 gtex_brain_putamen_basal
RS1655914 6 29921927 HLA-A ENSG00000206503.7 2.392E-6 0 12890 gtex_brain_putamen_basal
rs5027910 6 29922073 HLA-A ENSG00000206503.7 2.775E-8 0 13036 gtex_brain_putamen_basal
RS1632874 6 29922123 HLA-A ENSG00000206503.7 2.786E-6 0 13086 gtex_brain_putamen_basal
rs5027912 6 29922177 HLA-A ENSG00000206503.7 2.735E-8 0 13140 gtex_brain_putamen_basal
rs5027913 6 29922199 HLA-A ENSG00000206503.7 2.689E-8 0 13162 gtex_brain_putamen_basal
RS9260584 6 29922448 HLA-A ENSG00000206503.7 1.585E-6 0 13411 gtex_brain_putamen_basal
RS9260599 6 29922653 HLA-A ENSG00000206503.7 4.251E-8 0 13616 gtex_brain_putamen_basal
RS1655915 6 29922934 HLA-A ENSG00000206503.7 1.618E-6 0 13897 gtex_brain_putamen_basal
RS9260614 6 29922995 HLA-A ENSG00000206503.7 2.687E-8 0 13958 gtex_brain_putamen_basal
RS1632873 6 29923497 HLA-A ENSG00000206503.7 1.615E-6 0 14460 gtex_brain_putamen_basal
rs2571390 6 29923554 HLA-A ENSG00000206503.7 9.323E-8 0 14517 gtex_brain_putamen_basal
rs2844810 6 29923580 HLA-A ENSG00000206503.7 4.22E-8 0 14543 gtex_brain_putamen_basal

Section II. Transcriptome annotation

基因ral gene expression (GTEx)

无法使用

Devlopment期间的基因表达（BrainCloud）

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

时间变化的基因表达（brainspan）

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1：胎儿（13-26个概念后周），ST2：婴儿早期至童年（4个月至11年）和ST3：青春期至成年期（13-23年）
所示的栏表示表达分布的较低25％和上层25％。

Top co-expressed genes in brain regions

前10个积极共表达的基因
基因 Pearson's Correlation Spearman's Correlation
HLA-DRB5 0.86 0.91
CD74 0.84 0.88
HLA-DQB1 0.82 0.82
HLA-DPA1 0.79 0.86
HLA-DRA 0.79 0.84
HLA-DPB1 0.79 0.81
ANXA11 0.74 0.81
HLA-DMB 0.74 0.77
CTSF 0.73 0.72
me1 0.73 0.80
Top 10 negatively co-expressed genes
基因 Pearson's Correlation Spearman's Correlation
KIAA1949 -0.59 -0.59
TUBB2B -0.58 -0.65
SH3BP2 -0.58 -0.66
nkiras2 -0.57 -0.55
ZNF300 -0.57 -0.56
AL033532.1 -0.56 -0.58
ZNF311 -0.56 -0.59
ZNF551 -0.56 -0.56
CCDC123 -0.56 -0.55
AC004017.1 -0.56 -0.56

Section III. Gene Ontology annotation

Molecular function GO term 证据 神经关键字 PubMed ID
GO:0005515 蛋白质结合 IPI 12414957|17353931
GO：0032393 MHC I类受体活动 nas 1431115|2437024|2715640
|6609814|8188325
生物过程 GO term 证据 神经关键字 PubMed ID
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I IEA -
GO：0019882 antigen processing and presentation IEA -
去：0006955 免疫反应 IEA -
去：0006955 免疫反应 nas 1431115|2437024|2715640
|6609814|8188325
GO:0044419 生物之间的种间相互作用 IEA -
Cellular component GO term 证据 神经关键字 PubMed ID
GO:0000139 高尔基膜 经验 15569716
GO:0016020 膜 IEA -
GO:0016021 integral to membrane IEA -
GO:0005887 质膜的积分 nas 1431115|2437024|2715640
|6609814|8188325
GO：0042612 MHC class I protein complex IEA -
GO：0031901 early endosome membrane 经验 15569716

第四节。蛋白质蛋白相互作用注释

互动者 别名b 官方全名b Experimental Source PubMed ID
B2M - beta-2-microglobulin - HPRD 93026
CALR CRT |FLJ26680 |ro |SSA |CC1QR calreticulin CRT interacts with HLA-A2. This interaction was modeled on a demonstrated interaction between rabbit CRT and human HLA-A2. 绑定 15383281
CD8A CD8 | Leu2 | MAL | p32 CD8a molecule - HPRD，Biogrid 9177355|10809759|10809759
COPB1 COPB |DKFZP761K102 |FLJ10341 coatomer protein complex, subunit beta 1 亲和力捕获 - 韦斯特恩 Biogrid 11884415
COPG copg1 |FLJ21068 coatomer protein complex, subunit gamma 亲和力捕获 - 韦斯特恩 Biogrid 11884415
derl1 DER-1 | DER1 | FLJ13784 | FLJ42092 | MGC3067 | PRO2577 Der1-like domain family, member 1 - HPRD，Biogrid 15215855
ERBB2 CD340 |her-2 |her-2/neu |her2 |neu |ngl |TKR1 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) - HPRD，Biogrid 10593938
KIR3DL2 CD158K |MGC125321 |nkat4 |NKAT4B |P140 杀伤细胞免疫球蛋白样受体，三个结构域，长细胞质尾巴，2 - HPRD，Biogrid 8617928|8760804
lilrb1 CD85 |CD85J |FLJ37515 |Ilt2 |lir-1 |lir1 |mir-7 |mir7 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 - HPRD，Biogrid 12897781
lilrb2 CD85D |Ilt4 |Lilra6 |lir-2 |lir2 |mir-10 |mir10 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 - HPRD，Biogrid 9531263|12853576
MAGEA1 mage1 |MGC9326 黑色素瘤抗原家族A，1（指导抗原MZ2-E的表达） Reconstituted Complex Biogrid 8647853
MAGEA4 MAGE-41 | MAGE-X2 | MAGE4 | MAGE4A | MAGE4B | MGC21336 melanoma antigen family A, 4 - HPRD，Biogrid 11502003
TAP1 ABC17 | ABCB2 | APT1 | D6S114E | FLJ26666 | FLJ41500 | PSF1 | RING4 | TAP1*0102N | TAP1N 转运蛋白1，ATP结合盒，亚家族B（MDR/TAP） 亲和力捕获 - 韦斯特恩 Biogrid 11884415
TAPBP NGS17 | TAPA | TPN | TPSN | tapasin 点击结合蛋白（木薯蛋白） - HPRD 8769474
TAPBP NGS17 | TAPA | TPN | TPSN | tapasin 点击结合蛋白（木薯蛋白） 亲和力捕获 - 韦斯特恩 Biogrid 11884415
tra@ FLJ22602 |MGC117436 |MGC22624 |MGC23964 |MGC71411 |tcra |TCRD |特拉 T细胞受体α基因座 - HPRD，Biogrid 9586631
trb@ TCRB | TRB T细胞受体β基因座 Co-crystal Structure Biogrid 9586631
UGCGL1 FLJ23671 |FLJ23796 |Hugt1 UDP-glucose ceramide glucosyltransferase-like 1 亲和力捕获ms Biogrid 17353931


V.途径注释

Pathway name Pathway size # SZGR 2.0 genes in pathway 信息
KEGG ENDOCYTOSIS 183 132 该途径中的所有SZGR 2.0基因
KEGG CELL ADHESION MOLECULES CAMS 134 93 该途径中的所有SZGR 2.0基因
KEGG ANTIGEN PROCESSING AND PRESENTATION 89 65 该途径中的所有SZGR 2.0基因
KEGG NATURAL KILLER CELL MEDIATED CYTOTOXICITY 137 92 该途径中的所有SZGR 2.0基因
KEGG TYPE I DIABETES MELLITUS 44 3.8 该途径中的所有SZGR 2.0基因
KEGG自身免疫性甲状腺疾病 53 49 该途径中的所有SZGR 2.0基因
KEGG同种异体拒绝 3.8 3.4 该途径中的所有SZGR 2.0基因
KEGG GRAFT VERSUS HOST DISEASE 42 3.1 该途径中的所有SZGR 2.0基因
KEGG VIRAL MYOCARDITIS 73 58 该途径中的所有SZGR 2.0基因
BIOCARTA CTL PATHWAY 15 11 该途径中的所有SZGR 2.0基因
Biocarta nkcells途径 20 13 该途径中的所有SZGR 2.0基因
PID IL12 2 Pathway 63 54 该途径中的所有SZGR 2.0基因
PID CD8 TCR途径 53 42 该途径中的所有SZGR 2.0基因
PID AP1途径 70 60 该途径中的所有SZGR 2.0基因
PID CD8 TCR DOWNSTREAM PATHWAY 65 56 该途径中的所有SZGR 2.0基因
Reactome NEF介导的MHC I类复杂细胞表面表达的下调 10 5 该途径中的所有SZGR 2.0基因
Reactome抗原加工交叉呈现 76 48 该途径中的所有SZGR 2.0基因
反应组内体液泡途径 9 7 该途径中的所有SZGR 2.0基因
Reactome ER吞噬体途径 61 40 该途径中的所有SZGR 2.0基因
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS 21 12 该途径中的所有SZGR 2.0基因
淋巴机与非淋巴样细胞之间的反应组免疫调节性相互作用 70 3.7 该途径中的所有SZGR 2.0基因
Reactome干扰素伽马信号传导 63 48 该途径中的所有SZGR 2.0基因
Reactome干扰素αβ信号传导 64 50 该途径中的所有SZGR 2.0基因
REACTOME INTERFERON SIGNALING 159 116 该途径中的所有SZGR 2.0基因
REACTOME HIV INFECTION 207 122 该途径中的所有SZGR 2.0基因
Reactome宿主的艾滋病毒因素的相互作用 132 81 该途径中的所有SZGR 2.0基因
REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS 28 19 该途径中的所有SZGR 2.0基因
REACTOME IMMUNE SYSTEM 933 616 该途径中的所有SZGR 2.0基因
Reactome适应性免疫系统 539 3.50 该途径中的所有SZGR 2.0基因
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 270 204 该途径中的所有SZGR 2.0基因
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC 21 17 该途径中的所有SZGR 2.0基因
Reactome I类MHC介导的抗原加工表现 251 156 该途径中的所有SZGR 2.0基因
Doane对雄激素DN的反应 241 146 该途径中的所有SZGR 2.0基因
ENK UV RESPONSE KERATINOCYTE UP 530 3.42 该途径中的所有SZGR 2.0基因
WANG ESOPHAGUS CANCER VS NORMAL UP 121 72 该途径中的所有SZGR 2.0基因
EBAUER TARGETS OF PAX3 FOXO1 FUSION UP 207 128 该途径中的所有SZGR 2.0基因
Dacosta UV响应通过ERCC3 UP 3.09 199 该途径中的所有SZGR 2.0基因
JAZAG TGFB1 SIGNALING UP 108 69 该途径中的所有SZGR 2.0基因
ALCALA APOPTOSIS 88 60 该途径中的所有SZGR 2.0基因
MANTOVANI VIRAL GPCR SIGNALING DN 49 3.7 该途径中的所有SZGR 2.0基因
LIU NASOPHARYNGEAL CARCINOMA 70 3.8 该途径中的所有SZGR 2.0基因
SCHAEFFER PROSTATE DEVELOPMENT 48HR UP 487 286 该途径中的所有SZGR 2.0基因
COLIN PILOCYTIC ASTROCYTOMA VS GLIOBLASTOMA UP 3.5 3.2 该途径中的所有SZGR 2.0基因
BENPORATH EED TARGETS 1062 725 该途径中的所有SZGR 2.0基因
与H3K27me3的Benporath ES 1118 744 该途径中的所有SZGR 2.0基因
Benporath Myc Max目标 775 494 该途径中的所有SZGR 2.0基因
IIZUKA LIVER CANCER PROGRESSION L0 L1 DN 21 14 该途径中的所有SZGR 2.0基因
der ifn alpha响应 74 48 该途径中的所有SZGR 2.0基因
HBV感染的Wieland 101 66 该途径中的所有SZGR 2.0基因
der ifn beta响应 102 67 该途径中的所有SZGR 2.0基因
萨那对ifng的回应 78 50 该途径中的所有SZGR 2.0基因
SANA TNF SIGNALING UP 83 56 该途径中的所有SZGR 2.0基因
SHIPP DLBCL VS FOLLICULAR LYMPHOMA DN 45 28 该途径中的所有SZGR 2.0基因
FLECHNER BIOPSY KIDNEY TRANSPLANT OK VS DONOR UP 555 3.46 该途径中的所有SZGR 2.0基因
der ifn伽马响应 71 45 该途径中的所有SZGR 2.0基因
Chiba对TSA的反应 52 3.3. 该途径中的所有SZGR 2.0基因
RODWELL AGING KIDNEY UP 487 3.03. 该途径中的所有SZGR 2.0基因
KRIGE RESPONSE TO TOSEDOSTAT 6HR UP 953 554 该途径中的所有SZGR 2.0基因
Krige对Tosedostat的反应24小时 783 442 该途径中的所有SZGR 2.0基因
Kim LRC3B目标 3.0 24 该途径中的所有SZGR 2.0基因
PELLICCIOTTA HDAC IN ANTIGEN PRESENTATION DN 49 3.8 该途径中的所有SZGR 2.0基因
GAURNIER PSMD4 TARGETS 73 55 该途径中的所有SZGR 2.0基因
Goldrath抗原反应 3.46 192 该途径中的所有SZGR 2.0基因
炎症反应和胆固醇DN 12 7 该途径中的所有SZGR 2.0基因
Lee早期T淋巴细胞DN 57 3.6 该途径中的所有SZGR 2.0基因
HSIAO HOUSEKEEPING GENES 3.89 245 该途径中的所有SZGR 2.0基因
JISON SICKLE CELL DISEASE UP 181 106 该途径中的所有SZGR 2.0基因
黑川肝癌早期复发DN 7 6 该途径中的所有SZGR 2.0基因
SENGUPTA EBNA1 ANTICORRELATED 173 85 该途径中的所有SZGR 2.0基因
Pilon KLF1靶向 504 3.21 该途径中的所有SZGR 2.0基因
JOHNSTONE PARVB TARGETS 2 UP 140 94 该途径中的所有SZGR 2.0基因
PEDERSEN METASTASIS BY ERBB2 ISOFORM 7 403 240 该途径中的所有SZGR 2.0基因
phong tnf响应不是通过p38 3.3.7 236 该途径中的所有SZGR 2.0基因