Gene Page:EIF4E3

Summary?
GeneID 317649
Symbol EIF4E3
Synonyms eIF-4E3|eIF4E-3
Description eukaryotic translation initiation factor 4E family member 3
Reference MIM:609896|HGNC:HGNC:31837|Ensembl:ENSG00000163412|HPRD:10687|
Gene type protein-coding
Map location 3p14
Pascal p-value 0.022
eGene Hippocampus

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
GSMA_IIE Genome scan meta-analysis (European-ancestry samples) Psr: 0.04359
GSMA_IIA Genome scan meta-analysis (All samples) Psr: 0.04047

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception周),ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section III. Gene Ontology annotation

Molecular function 去的术语 Evidence Neuro keywords PubMed ID
GO:0003723 RNA binding IEA -
GO:0003743 translation initiation factor activity IEA -
Biological process 去的术语 Evidence Neuro keywords PubMed ID
GO:0006413 translational initiation IEA -
GO:0006417 regulation of translation IEA -
Cellular component 去的术语 Evidence Neuro keywords PubMed ID
GO:0005737 cytoplasm IEA -

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES 66 45 All SZGR 2.0 genes in this pathway
REACTOME INTERFERON SIGNALING 159 116 All SZGR 2.0 genes in this pathway
REACTOME IMMUNE SYSTEM 933 616 All SZGR 2.0 genes in this pathway
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 270 204 All SZGR 2.0 genes in this pathway
RODRIGUES THYROID CARCINOMA POORLY DIFFERENTIATED DN 805 505 All SZGR 2.0 genes in this pathway
RODRIGUES THYROID CARCINOMA ANAPLASTIC DN 537 339 All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN UP 1142 669 All SZGR 2.0 genes in this pathway
GRAESSMANN RESPONSE TO MC AND DOXORUBICIN UP 612 367 All SZGR 2.0 genes in this pathway
BENPORATH SUZ12 TARGETS 1038 678 All SZGR 2.0 genes in this pathway
BENPORATH ES WITH H3K27ME3 1118 744 All SZGR 2.0 genes in this pathway
DOUGLAS BMI1 TARGETS UP 566 371 All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 UNSTIMULATED 1229 713 All SZGR 2.0 genes in this pathway
ZHANG BREAST CANCER PROGENITORS DN 145 93 All SZGR 2.0 genes in this pathway
RAY TUMORIGENESIS BY ERBB2 CDC25A DN 159 105 All SZGR 2.0 genes in this pathway
HUANG DASATINIB RESISTANCE DN 69 44 All SZGR 2.0 genes in this pathway
BEIER GLIOMA STEM CELL DN 66 42 All SZGR 2.0 genes in this pathway
CHANG CORE SERUM RESPONSE DN 209 137 All SZGR 2.0 genes in this pathway
MEISSNER NPC HCP WITH H3K4ME2 AND H3K27ME3 349 234 All SZGR 2.0 genes in this pathway
MIKKELSEN NPC HCP WITH H3K27ME3 341 243 All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN 1972 1213 All SZGR 2.0 genes in this pathway
TORCHIA TARGETS OF EWSR1 FLI1 FUSION DN 321 200 All SZGR 2.0 genes in this pathway
WANG MLL TARGETS 289 188 All SZGR 2.0 genes in this pathway
DURAND STROMA S UP 297 194 All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family Target position miRNA ID miRNA seq
UTR start UTR end Match method
miR-142-5p 1868 1874 m8 hsa-miR-142-5p CAUAAAGUAGAAAGCACUAC
miR-186 17 23 m8 hsa-miR-186 CAAAGAAUUCUCCUUUUGGGCUU
miR-208 51 57 1A hsa-miR-208 AUAAGACGAGCAAAAAGCUUGU
miR-221/222 1913 1919 m8 hsa-miR-221brain AGCUACAUUGUCUGCUGGGUUUC
hsa-miR-222brain AGCUACAUCUGGCUACUGGGUCUC
miR-338 94 100 m8 hsa-miR-338brain UCCAGCAUCAGUGAUUUUGUUGA
miR-365 519 525 m8 hsa-miR-365 UAAUGCCCCUAAAAAUCCUUAU
miR-421 344 350 1A hsa-miR-421 GGCCUCAUUAAAUGUUUGUUG
miR-499 51 57 1A hsa-miR-499 UUAAGACUUGCAGUGAUGUUUAA