Gene Page:HRAS

Summary？
基因 3265
Symbol HRAS
同义词 c-bas/has | c-h-ras | c-ha-ras1 | ctlo | h-rasidx | hamsv | hras1 | rash1 | p21ras
描述 Harvey rat sarcoma viral oncogene homolog
参考 MIM:190020|HGNC：HGNC：5173|Ensembl：ENSG00000174775|HPRD:01813|Vega：Otthumg00000131919
Gene type 蛋白质编码
Map location 11P15.5
Pascal P值 0.095
Sherlock p-value 0.76
胎儿β -0.557
主持人 Cerebellum
Cortex
Nucleus accumbens basal ganglia
梭子基底神经节
Myers' cis & trans
元
Support INTRACELLULAR SIGNAL TRANSDUCTION
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2CDB.HUMANNRC
G2Cdb.humanPSD
G2Cdb.humanPSP

Gene in Data Sources
Gene set name 基因组方法 描述 信息
CV:PGCnp Genome-wide Association Study GWAS
PMID：cooccur 高通量文献搜索 Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
文学 高通量文献搜索 Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias 点击显示详细信息
go_annotation Mapping neuro-related keywords to Gene Ontology annotations Hits with neuro-related keywords: 3
Network Shortest path distance of core genes in the Human protein-protein interaction network Contribution to shortest path in PPI network: 0.0119

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position 主持人 Gene Entrez ID pvalue QVALUE TSS距离 EQTL类型
RS2809658 chr1 43050395 HRAS 3265 0.1 trans
rs61876339 11 495283 HRAS ENSG00000174775.12 1.78941E-6 0.01 42004 gtex_brain_putamen_basal
rs12807963 11 518280 HRAS ENSG00000174775.12 7.20226E-7 0.01 19007 gtex_brain_putamen_basal

第二节。转录组注释

一般基因表达（GTEX）

Not available

Gene expression during devlopment (BrainCloud)

脚注：
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

(B基因表达的时空变化rainSpan)

脚注：
SC:分皮质区域;SM:感觉运动区域s; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


第三节。基因本体论注释

分子功能 去学期 证据 神经关键字 PubMed ID
GO:0000166 nucleotide binding IEA -
GO:0003924 GTPase活性 IEA -
去：0005515 蛋白质结合 IEA -
去：0005525 GTP binding IEA -
GO:0008022 protein C-terminus binding IPI 9219684
生物过程 去学期 证据 神经关键字 PubMed ID
GO:0048169 regulation of long-term neuronal synaptic plasticity IEA neuron, Synap (GO term level: 10) -
GO:0032228 调节突触传播，GABA能量 IEA neuron, GABA, Synap, Neurotransmitter (GO term level: 9) -
GO:0043524 negative regulation of neuron apoptosis IEA neuron (GO term level: 9) -
去：0007265 Ras protein signal transduction EXP 11520933
去：0007265 Ras protein signal transduction IEA -
GO:0009887 organ morphogenesis TAS 10848592
GO:0007166 细胞表面受体连接的信号转导 TAS 9020890
去：0008284 positive regulation of cell proliferation IEA -
GO:0008542 visual learning IEA -
去：0007569 细胞衰老 IEA -
GO:0006935 chemotaxis TAS 10848592
去：0007264 small GTPase mediated signal transduction IEA -
去：0006897 endocytosis IEA -
GO:0030036 actin cytoskeleton organization IEA -
GO:0035022 RAC蛋白信号转导的正调控 IEA -
GO:0051146 striated muscle cell differentiation IEA -
细胞分量 去学期 证据 神经关键字 PubMed ID
去：0000139 高尔基膜 IEA -
去：0005794 Golgi apparatus IEA -
GO:0005622 细胞内 IEA -
GO:0005624 membrane fraction IEA -
去：0005737 细胞质 TAS 10842192
GO:0005886 plasma membrane EXP 7972015|8493579|9069260
|9690470
GO:0005886 plasma membrane TAS 9020890|9880516

Section IV. Protein-protein interaction annotation

Interactors Aliases B Official full name B 实验 资源 PubMed ID
APBB1IP inag1 |PREL1 |RARP1 |里亚姆 淀粉样β（A4）前体蛋白结合，族B，成员1相互作用蛋白 Riam与Ras互动。 BIND 15469846
阿拉夫 a-raf |araf1 |pks2 |rafa1 V-RAF鼠肉瘤3611病毒癌基因同源物 阿拉夫(A-Raf) interacts with an unspecified isoform of HRAS (Ha-Ras). BIND 12620389
ARHGEF1 GEF1 |lbcl2 |LSC |p115-rhogef |Sub1.5 Rho鸟嘌呤核苷酸交换因子（GEF）1 生化活动 Biogrid 12581858
BCL2 Bcl-2 B-cell CLL/lymphoma 2 - HPRD 10490827
BRAF B-RAF1 |Braf1 |FLJ95109 |MGC126806 |MGC138284 |Rafb1 V-RAF鼠类肉瘤病毒癌基因同源物B1 - HPRD,BioGRID 7706312
BRAP BRAP2 | IMP | RNF52 BRCA1相关蛋白 IMP与RAS相互作用。 BIND 14724641
cdc25a cdc25a2 cell division cycle 25 homolog A (S. pombe) - HPRD 7744247
DGKZ DAGK5 | DAGK6 | DGK-ZETA | hDGKzeta diacylglycerol kinase, zeta 104kDa - HPRD,BioGRID 11257115
erbb2ip ERBIN | LAP2 ERBB2相互作用蛋白 - HPRD,BioGRID 12379659
GPSM2 lgn |别针 G-protein signaling modulator 2 (AGS3-like, C. elegans) - HPRD,BioGRID 12748287
GRB2 灰烬|EGFRBP-GRB2 |Grb3-3 |MST084 |MSTP084 growth factor receptor-bound protein 2 - HPRD 11352655
GRIN1 NMDA1 | NMDAR1 | NR1 谷氨酸受体，离子型，N-甲基D-天冬氨酸1 - HPRD 10862698
ikzf3 AIO |蒜泥蛋黄酱|Znfn1a3 IKAROS family zinc finger 3 (Aiolos) - HPRD,BioGRID 10369681
INSR CD220 |HHF5 insulin receptor - HPRD,BioGRID 3109943
IRAK1 irak |佩尔 白介素-1受体相关激酶1 - HPRD 11744690
IRAK2 irak-2 |MGC150550 白介素-1受体相关激酶2 - HPRD 11744690
LGALS1 DKFZp686E23103 | GAL1 | GBP 凝集素，半乳糖苷结合，可溶性，1 - HPRD,BioGRID 11709720
MAP2K1 MAPKK1 | MEK1 | MKK1 | PRKMK1 mitogen-activated protein kinase kinase 1 - HPRD,BioGRID 7969158
MAPK8 jnk |JNK1 |JNK1A2 |JNK21B1/2 |prkm8 |SAPK1 有丝分裂原激活的蛋白激酶8 - HPRD 8137421|11525649
mllt4 AF-6 |AF6 |Afadin |FLJ34371 |RP3-431P23.3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 - HPRD,BioGRID 10922060
NF1 DKFZp686J1293 | FLJ21220 | NFNS | VRNF | WSS neurofibromin 1 - HPRD,BioGRID 8628317
PDE6D PDED phosphodiesterase 6D, cGMP-specific, rod, delta - HPRD,BioGRID 11980706
PDGFB FLJ12858 | PDGF2 | SIS | SSV | c-sis 血小板衍生的生长因子β多肽（Simian肉瘤病毒（V-SIS）癌基因同源物） - HPRD 10485711
PIK3CA MGC142161 | MGC142163 | PI3K | p110-alpha phosphoinositide-3-kinase, catalytic, alpha polypeptide - HPRD 9150145
PIK3CA MGC142161 | MGC142163 | PI3K | p110-alpha phosphoinositide-3-kinase, catalytic, alpha polypeptide 重构的复合物
Two-hybrid		 Biogrid 8665852|10783161
|14724584
pik3cd p110D phosphoinositide-3-kinase, catalytic, delta polypeptide Two-hybrid Biogrid 10922060
pik3cg PI3CG | PI3K | PI3Kgamma | PIK3 phosphoinositide-3-kinase, catalytic, gamma polypeptide - HPRD,BioGRID 11136978
PIK3R1 grb1 |P85 |p85-alpha 磷酸肌醇3-激酶，调节亚基1（alpha） - HPRD,BioGRID 10212255
PLAU ATF | UPA | URK | UROKINASE | u-PA 纤溶酶原激活剂，尿激酶 表型抑制 Biogrid 10402467
Rabac1 PRA1 | PRAF1 | YIP3 Rab acceptor 1 (prenylated) - HPRD 11335720
RAF1 克拉夫|NS5 |RAF-1 |C-Raf v-raf-1 murine leukemia viral oncogene homolog 1 - HPRD 8530446|8911690
RAF1 克拉夫|NS5 |RAF-1 |C-Raf v-raf-1 murine leukemia viral oncogene homolog 1 Hras interacts with Raf. This interaction was modelled on a demonstrated interaction between Hras and Raf, both from an unspecified species. BIND 15705808
RAF1 克拉夫|NS5 |RAF-1 |C-Raf v-raf-1 murine leukemia viral oncogene homolog 1 RAF与RAS相互作用。这种相互作用是根据人RAF和大鼠RAS之间的相互作用建模的。 BIND 11585923
RAF1 克拉夫|NS5 |RAF-1 |C-Raf v-raf-1 murine leukemia viral oncogene homolog 1 RAF1 (C-Raf) interacts with HRAS (Ha-Ras). BIND 12620389
RAF1 克拉夫|NS5 |RAF-1 |C-Raf v-raf-1 murine leukemia viral oncogene homolog 1 RAF-1与RAS相互作用。 BIND 15664191
RAF1 克拉夫|NS5 |RAF-1 |C-Raf v-raf-1 murine leukemia viral oncogene homolog 1 C-RAF interacts with Ha-Ras. BIND 12620389
RAF1 克拉夫|NS5 |RAF-1 |C-Raf v-raf-1 murine leukemia viral oncogene homolog 1 RAF与RAS相互作用。这种相互作用是根据RAF与未指定的来源和人类RAS之间的相互作用进行建模的。 BIND 7523381|8307946
RAF1 克拉夫|NS5 |RAF-1 |C-Raf v-raf-1 murine leukemia viral oncogene homolog 1 亲和力捕获 - 韦斯特恩
重构的复合物
Two-hybrid		 Biogrid 7862125|7969158
|8530446|8628317
|9150145|9154803
|9523700|10369681
|10783161|10882715
|10922060|12379659
|12620389|14654780
|14724584|15031288
|16803888
RALA MGC48949 | RAL V-ral Simian白血病病毒癌基因同源物A（与RAS相关） Two-hybrid Biogrid 11786539
RALGDS FLJ20922 |RGF |拉尔奇夫 鸟嘌呤核苷酸解离刺激剂 RAS与Ralgds的羧基末端相互作用。这种相互作用是根据人Ras和大鼠ralgds之间的相互作用进行建模的。 BIND 9516482
RALGDS FLJ20922 |RGF |拉尔奇夫 鸟嘌呤核苷酸解离刺激剂 重构的复合物
Two-hybrid		 Biogrid 7809086|7972015
|9038168|9150145
|10783161|10922060
|15031288
RALGDS FLJ20922 |RGF |拉尔奇夫 鸟嘌呤核苷酸解离刺激剂 - HPRD 7972015|9038168
RAP1GDS1 GDS1 |MGC118859 |MGC118861 |smggds RAP1，GTP-GDP解离刺激器1 - HPRD,BioGRID 11948427
rasa1 CM-AVM | CMAVM | DKFZp434N071 | GAP | PKWS | RASA | RASGAP | p120GAP | p120RASGAP Ras P21蛋白激活剂（GTPase激活蛋白）1 - HPRD,BioGRID 7628625|9219684
rasa1 CM-AVM | CMAVM | DKFZp434N071 | GAP | PKWS | RASA | RASGAP | p120GAP | p120RASGAP Ras P21蛋白激活剂（GTPase激活蛋白）1 - HPRD 2833817|7628625
|8663024|9219684
rasgrf1 CDC25 | CDC25L | GNRP | GRF1 | GRF55 | H-GRF55 | PP13187 RAS蛋白特异性鸟嘌呤核苷酸释放因子1 Two-hybrid Biogrid 9154803
RASGRP4 - Ras鸟甘释放蛋白4 - HPRD 11880369
RASIP1 FLJ20401 |雨 RAS相互作用蛋白1 - HPRD,BioGRID 15031288
RASSF1 123f2 |nore2a |RASSF1A |RDA32 |REH3P21 Ras association (RalGDS/AF-6) domain family member 1 - HPRD,BioGRID 10998413
RASSF2 DKFZP781O1747 |KIAA0168 |拉斯法丁 Ras association (RalGDS/AF-6) domain family member 2 - HPRD 12732644
RASSF5 MGC10823 | MGC17344 | Maxp1 | NORE1 | NORE1A | NORE1B | RAPL | RASSF3 Ras association (RalGDS/AF-6) domain family member 5 重构的复合物 Biogrid 9488663
RGL2 HKE1.5 |ke1.5 |rab2l 鸟嘌呤核苷酸解离刺激剂-like 2 重构的复合物
Two-hybrid		 Biogrid 8939933|15031288
RGL4 MGC119678 | MGC119680 | Rgr 鸟嘌呤核苷酸解离刺激剂-like 4 - HPRD,BioGRID 12874025
RHEB MGC111559 | RHEB2 Ras homolog enriched in brain 亲和力捕获 - 韦斯特恩 Biogrid 15854902
RIN1 - Ras and Rab interactor 1 重构的复合物
Two-hybrid		 Biogrid 7862125|15031288
RIN1 - Ras and Rab interactor 1 - HPRD 7862125|9144171
SHOC2 FLJ60412 | KIAA0862 | SIAA0862 | SOC-2 | SOC2 | SUR-8 | SUR8 soc-2 suppressor of clear homolog (C. elegans) - HPRD,BioGRID 9674433|10783161
SOS1 GF1 |GGF1 |gingf |HGF |NS4 son of sevenless homolog 1 (Drosophila) - HPRD 9690470|11560935
SOS1 GF1 |GGF1 |gingf |HGF |NS4 son of sevenless homolog 1 (Drosophila) 共晶结构 Biogrid 9690470|12628188
SOS2 FLJ25596 son of sevenless homolog 2 (Drosophila) - HPRD 12628188
TIAM1 FLJ36302 T细胞淋巴瘤侵袭和转移1 - HPRD,BioGRID 12134164
TTC1 FLJ46404 |TPR1 tetratricopeptide repeat domain 1 - HPRD,BioGRID 12748287
VAV1 VAV VAV 1鸟嘌呤核苷酸交换因子 - HPRD 8554611
ZBTB12 bat9 |C6orf46 |D6S59E |G10 |NG35 zinc finger and BTB domain containing 12 - HPRD 8939933


Section V. Pathway annotation

Pathway name 路径大小 ＃szgr 2.0基因 信息
kegg mapk信号通路 267 205 All SZGR 2.0 genes in this pathway
kegg erbb信号通路 87 71 All SZGR 2.0 genes in this pathway
KEGG趋化因子信号传导途径 190 128 All SZGR 2.0 genes in this pathway
KEGG内吞作用 183 132 All SZGR 2.0 genes in this pathway
KEGG AXON GUIDANCE 129 103 All SZGR 2.0 genes in this pathway
KEGG VEGF SIGNALING PATHWAY 76 53 All SZGR 2.0 genes in this pathway
kegg焦点粘附 201 138 All SZGR 2.0 genes in this pathway
kegg thright连接点 134 86 All SZGR 2.0 genes in this pathway
KEGG GAP JUNCTION 90 68 All SZGR 2.0 genes in this pathway
KEGG NATURAL KILLER CELL MEDIATED CYTOTOXICITY 137 92 All SZGR 2.0 genes in this pathway
KEGG T CELL RECEPTOR SIGNALING PATHWAY 108 89 All SZGR 2.0 genes in this pathway
KEGG B CELL RECEPTOR SIGNALING PATHWAY 75 56 All SZGR 2.0 genes in this pathway
kegg fc epsilon ri信号传导途径 79 58 All SZGR 2.0 genes in this pathway
kegg长期增强 70 57 All SZGR 2.0 genes in this pathway
KEGG NEUROTROPHIN SIGNALING PATHWAY 126 103 All SZGR 2.0 genes in this pathway
KEGG LONG TERM DEPRESSION 70 53 All SZGR 2.0 genes in this pathway
KEGG REGULATION OF ACTIN CYTOSKELETON 216 144 All SZGR 2.0 genes in this pathway
KEGG胰岛素信号通路 137 103 All SZGR 2.0 genes in this pathway
KEGG GNRH SIGNALING PATHWAY 101 77 All SZGR 2.0 genes in this pathway
kegg黑色素发生 102 80 All SZGR 2.0 genes in this pathway
KEGG PATHWAYS IN CANCER 328 259 All SZGR 2.0 genes in this pathway
KEGG RENAL CELL CARCINOMA 70 60 All SZGR 2.0 genes in this pathway
KEGG ENDOMETRIAL CANCER 52 45 All SZGR 2.0 genes in this pathway
Kegg神经胶质瘤 65 56 All SZGR 2.0 genes in this pathway
KEGG前列腺癌 89 75 All SZGR 2.0 genes in this pathway
KEGG甲状腺癌 29 26 All SZGR 2.0 genes in this pathway
KEGG MELANOMA 71 57 All SZGR 2.0 genes in this pathway
Kegg膀胱癌 42 33 All SZGR 2.0 genes in this pathway
KEGG慢性髓细胞性白血病 73 59 All SZGR 2.0 genes in this pathway
Kegg急性髓样白血病 60 47 All SZGR 2.0 genes in this pathway
KEGG NON SMALL CELL LUNG CANCER 54 47 All SZGR 2.0 genes in this pathway
BIOCARTA AT1R PATHWAY 36 28 All SZGR 2.0 genes in this pathway
BIOCARTA SPPA PATHWAY 22 18 All SZGR 2.0 genes in this pathway
BIOCARTA BCR PATHWAY 37 28 All SZGR 2.0 genes in this pathway
生物卡丁生物肽途径 45 35 All SZGR 2.0 genes in this pathway
Biocarta CDMAC途径 16 15 All SZGR 2.0 genes in this pathway
Biocarta CCR3途径 23 21 All SZGR 2.0 genes in this pathway
Biocarta CXCR4途径 24 22 All SZGR 2.0 genes in this pathway
Biocarta EGF途径 31 25 All SZGR 2.0 genes in this pathway
BIOCARTA EPO PATHWAY 19 13 All SZGR 2.0 genes in this pathway
Biocarta ECM途径 24 17 All SZGR 2.0 genes in this pathway
BIOCARTA ERK PATHWAY 28 22 All SZGR 2.0 genes in this pathway
Biocarta FCER1途径 41 30 All SZGR 2.0 genes in this pathway
BIOCARTA FMLP PATHWAY 39 29 All SZGR 2.0 genes in this pathway
Biocarta GH途径 28 22 All SZGR 2.0 genes in this pathway
BIOCARTA MPR PATHWAY 34 28 All SZGR 2.0 genes in this pathway
BIOCARTA IGF1 PATHWAY 21 16 All SZGR 2.0 genes in this pathway
Biocarta IL2途径 22 16 All SZGR 2.0 genes in this pathway
BIOCARTA IL3 PATHWAY 15 11 All SZGR 2.0 genes in this pathway
BIOCARTA IL6 PATHWAY 22 16 All SZGR 2.0 genes in this pathway
BIOCARTA IL2RB PATHWAY 38 26 All SZGR 2.0 genes in this pathway
BIOCARTA RACCYCD PATHWAY 26 23 All SZGR 2.0 genes in this pathway
BIOCARTA GLEEVEC PATHWAY 23 17 All SZGR 2.0 genes in this pathway
BIOCARTA INSULIN PATHWAY 22 16 All SZGR 2.0 genes in this pathway
BIOCARTA INTEGRIN PATHWAY 38 29 All SZGR 2.0 genes in this pathway
BIOCARTA KERATINOCYTE PATHWAY 46 38 All SZGR 2.0 genes in this pathway
Biocarta Pyk2途径 31 24 All SZGR 2.0 genes in this pathway
BIOCARTA MAPK PATHWAY 87 68 All SZGR 2.0 genes in this pathway
BIOCARTA MCALPAIN PATHWAY 25 16 All SZGR 2.0 genes in this pathway
BIOCARTA ETS PATHWAY 18 12 All SZGR 2.0 genes in this pathway
BIOCARTA IGF1R PATHWAY 23 20 All SZGR 2.0 genes in this pathway
BIOCARTA NGF PATHWAY 18 13 All SZGR 2.0 genes in this pathway
Biocarta NFAT途径 56 45 All SZGR 2.0 genes in this pathway
BIOCARTA P38MAPK PATHWAY 40 31 All SZGR 2.0 genes in this pathway
Biocarta PDGF途径 32 25 All SZGR 2.0 genes in this pathway
BIOCARTA CDK5 PATHWAY 11 11 All SZGR 2.0 genes in this pathway
BIOCARTA RAS PATHWAY 23 20 All SZGR 2.0 genes in this pathway
BIOCARTA PML PATHWAY 17 12 All SZGR 2.0 genes in this pathway
Biocarta Cardiacegf途径 18 16 All SZGR 2.0 genes in this pathway
BIOCARTA HER2 PATHWAY 22 17 All SZGR 2.0 genes in this pathway
Biocarta ERK5途径 18 15 All SZGR 2.0 genes in this pathway
Biocarta mal通路 19 17 All SZGR 2.0 genes in this pathway
Biocarta Barrestin SRC途径 15 14 All SZGR 2.0 genes in this pathway
Biocarta遇到了途径 37 30 All SZGR 2.0 genes in this pathway
Biocarta GPCR途径 37 31 All SZGR 2.0 genes in this pathway
Biocarta Spry途径 18 15 All SZGR 2.0 genes in this pathway
BIOCARTA TCR PATHWAY 49 37 All SZGR 2.0 genes in this pathway
BIOCARTA LONGEVITY PATHWAY 15 13 All SZGR 2.0 genes in this pathway
BIOCARTA TPO PATHWAY 24 17 All SZGR 2.0 genes in this pathway
BIOCARTA CREB PATHWAY 27 25 All SZGR 2.0 genes in this pathway
BIOCARTA TFF PATHWAY 21 15 All SZGR 2.0 genes in this pathway
Biocarta TRKA途径 12 10 All SZGR 2.0 genes in this pathway
BIOCARTA VEGF PATHWAY 29 18 All SZGR 2.0 genes in this pathway
SA B细胞受体复合物 24 20 All SZGR 2.0 genes in this pathway
SA TRKA受体 17 15 All SZGR 2.0 genes in this pathway
PID FCER1 PATHWAY 62 43 All SZGR 2.0 genes in this pathway
PID内皮素路径 63 52 All SZGR 2.0 genes in this pathway
PID BCR 5PATHWAY 65 50 All SZGR 2.0 genes in this pathway
PID LYSOPHOSPHOLIPID PATHWAY 66 53 All SZGR 2.0 genes in this pathway
PID胰岛素途径 45 32 All SZGR 2.0 genes in this pathway
PID GMCSF PATHWAY 37 31 All SZGR 2.0 genes in this pathway
PID TCR PATHWAY 66 51 All SZGR 2.0 genes in this pathway
PID ER NONGENOMIC PATHWAY 41 35 All SZGR 2.0 genes in this pathway
PID遇到了路径 80 60 All SZGR 2.0 genes in this pathway
PID EPHB FWD途径 40 38 All SZGR 2.0 genes in this pathway
PID CDC42途径 70 51 All SZGR 2.0 genes in this pathway
PID RET路径 39 29 All SZGR 2.0 genes in this pathway
PID CD8 TCR途径 53 42 All SZGR 2.0 genes in this pathway
PID SHP2 PATHWAY 58 46 All SZGR 2.0 genes in this pathway
PID MTOR 4PATHWAY 69 55 All SZGR 2.0 genes in this pathway
PID IL2 1PATHWAY 55 43 All SZGR 2.0 genes in this pathway
PID IGF1 PATHWAY 30 23 All SZGR 2.0 genes in this pathway
PID ERBB1 RECEPTOR PROXIMAL PATHWAY 35 29 All SZGR 2.0 genes in this pathway
PID TCR RAS途径 14 14 All SZGR 2.0 genes in this pathway
PID PI3KCI PATHWAY 49 40 All SZGR 2.0 genes in this pathway
pid ajdiss 2Pathway 48 38 All SZGR 2.0 genes in this pathway
PID ERBB1下游途径 105 78 All SZGR 2.0 genes in this pathway
PID ERBB2 ERBB3 PATHWAY 44 35 All SZGR 2.0 genes in this pathway
PID PDGFRB途径 129 103 All SZGR 2.0 genes in this pathway
PID TRKR PATHWAY 62 48 All SZGR 2.0 genes in this pathway
PID CMYB途径 84 61 All SZGR 2.0 genes in this pathway
PID AR NONGENOMIC PATHWAY 31 27 All SZGR 2.0 genes in this pathway
PID ERBB1 INTERNALIZATION PATHWAY 41 35 All SZGR 2.0 genes in this pathway
PID CXCR3 PATHWAY 43 34 All SZGR 2.0 genes in this pathway
PID KIT PATHWAY 52 40 All SZGR 2.0 genes in this pathway
PID EPO PATHWAY 34 29 All SZGR 2.0 genes in this pathway
PID A6B1 A6B4整合素途径 46 35 All SZGR 2.0 genes in this pathway
PID Syndecan 2途径 33 27 All SZGR 2.0 genes in this pathway
PID RAS PATHWAY 30 22 All SZGR 2.0 genes in this pathway
PID MAPK TRK PATHWAY 34 31 All SZGR 2.0 genes in this pathway
PID PI3K PLC TRK途径 36 31 All SZGR 2.0 genes in this pathway
PID CD8 TCR DOWNSTREAM PATHWAY 65 56 All SZGR 2.0 genes in this pathway
REACTOME SIGNALLING BY NGF 217 167 All SZGR 2.0 genes in this pathway
SCF套件的Reactome信号传导 78 59 All SZGR 2.0 genes in this pathway
REACTOME DEVELOPMENTAL BIOLOGY 396 292 All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY ERBB4 90 67 All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY ERBB2 101 78 All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR 18 13 All SZGR 2.0 genes in this pathway
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING 22 20 All SZGR 2.0 genes in this pathway
EGFR在癌症中的反应组信号传导 109 80 All SZGR 2.0 genes in this pathway
ERBB4信号中的Reactome SHC1事件 20 17 All SZGR 2.0 genes in this pathway
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR 97 66 All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR 126 90 All SZGR 2.0 genes in this pathway
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE 87 64 All SZGR 2.0 genes in this pathway
Reactome Arms介导的激活 17 17 All SZGR 2.0 genes in this pathway
REACTOME PROLONGED ERK ACTIVATION EVENTS 19 18 All SZGR 2.0 genes in this pathway
REACTOME SIGNALLING TO RAS 27 23 All SZGR 2.0 genes in this pathway
反应组细胞表面相互作用在血管壁 91 65 All SZGR 2.0 genes in this pathway
Reactome NGF信号通过TRKA从质膜发出 137 105 All SZGR 2.0 genes in this pathway
向ERK的Reactome信号传导 36 30 All SZGR 2.0 genes in this pathway
Reactome P38MAPK事件 13 12 All SZGR 2.0 genes in this pathway
FGFR在疾病中的反应组信号传导 127 88 All SZGR 2.0 genes in this pathway
REACTOME SIGNALLING TO P38 VIA RIT AND RIN 15 14 All SZGR 2.0 genes in this pathway
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK 205 136 All SZGR 2.0 genes in this pathway
FGFR的Reactome信号传导MUTANTS 44 29 All SZGR 2.0 genes in this pathway
REACTOME SHC1 EVENTS IN EGFR SIGNALING 15 13 All SZGR 2.0 genes in this pathway
REACTOME TIE2 SIGNALING 17 13 All SZGR 2.0 genes in this pathway
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES 186 155 All SZGR 2.0 genes in this pathway
REACTOME NEURONAL SYSTEM 279 221 All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY GPCR 920 449 All SZGR 2.0 genes in this pathway
REACTOME NEUROTRANSMITTER RECEPTOR BINDING AND DOWNSTREAM TRANSMISSION IN THE POSTSYNAPTIC CELL 137 110 All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY PDGF 122 93 All SZGR 2.0 genes in this pathway
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION 95 76 All SZGR 2.0 genes in this pathway
REACTOME AXON GUIDANCE 251 188 All SZGR 2.0 genes in this pathway
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH 64 49 All SZGR 2.0 genes in this pathway
REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR 17 15 All SZGR 2.0 genes in this pathway
NMDA受体在谷氨酸结合和突触后事件上的反应组激活 37 32 All SZGR 2.0 genes in this pathway
Reactome Creb通过RAS激活的磷酸化 27 23 All SZGR 2.0 genes in this pathway
REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS 33 28 All SZGR 2.0 genes in this pathway
REACTOME FRS2 MEDIATED CASCADE 36 27 All SZGR 2.0 genes in this pathway
Reactome的下游信号传导激活的FGFR 100 74 All SZGR 2.0 genes in this pathway
REACTOME SHC MEDIATED CASCADE 28 19 All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY ILS 107 86 All SZGR 2.0 genes in this pathway
REACTOME IL 3 5 AND GM CSF SIGNALING 43 34 All SZGR 2.0 genes in this pathway
REACTOME IL RECEPTOR SHC SIGNALING 27 21 All SZGR 2.0 genes in this pathway
Reactome IL 2信号传导 41 34 All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY INSULIN RECEPTOR 108 72 All SZGR 2.0 genes in this pathway
REACTOME SOS MEDIATED SIGNALLING 14 13 All SZGR 2.0 genes in this pathway
反应组止血 466 331 All SZGR 2.0 genes in this pathway
REACTOME RAF MAP KINASE CASCADE 10 10 All SZGR 2.0 genes in this pathway
REACTOME SHC MEDIATED SIGNALLING 15 12 All SZGR 2.0 genes in this pathway
Reactome免疫系统 933 616 All SZGR 2.0 genes in this pathway
Reactome适应性免疫系统 539 350 All SZGR 2.0 genes in this pathway
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 270 204 All SZGR 2.0 genes in this pathway
FGFR的Reactome信号传导 112 80 All SZGR 2.0 genes in this pathway
REACTOME SHC RELATED EVENTS 17 13 All SZGR 2.0 genes in this pathway
Timofeeva生长应力通过STAT1 DN 16 12 All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER CLUSTER 3 DN 229 142 All SZGR 2.0 genes in this pathway
CHIN BREAST CANCER COPY NUMBER DN 16 10 All SZGR 2.0 genes in this pathway
阿霉素的Graessmann凋亡 1142 669 All SZGR 2.0 genes in this pathway
Graessmann对MC和阿霉素的反应 612 367 All SZGR 2.0 genes in this pathway
PEREZ TP53 TARGETS 1174 695 All SZGR 2.0 genes in this pathway
通过ELK3 UP总缺氧 209 139 All SZGR 2.0 genes in this pathway
GROSS HYPOXIA VIA HIF1A UP 77 49 All SZGR 2.0 genes in this pathway
带有E盒的WEI MYCN目标 795 478 All SZGR 2.0 genes in this pathway
LIAO METASTASIS 539 324 All SZGR 2.0 genes in this pathway
TP53和TP73的SCIAN细胞周期目标 9 7 All SZGR 2.0 genes in this pathway
RICKMAN METASTASIS DN 261 155 All SZGR 2.0 genes in this pathway
BENPORATH CYCLING GENES 648 385 All SZGR 2.0 genes in this pathway
KANNAN TP53 TARGETS UP 58 40 All SZGR 2.0 genes in this pathway
PENG GLUTAMINE DEPRIVATION DN 337 230 All SZGR 2.0 genes in this pathway
HOFMANN CELL LYMPHOMA DN 39 29 All SZGR 2.0 genes in this pathway
MODY HIPPOCAMPUS POSTNATAL 63 50 All SZGR 2.0 genes in this pathway
Kayo卡路里限制肌肉DN 87 59 All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 48HR DN 504 323 All SZGR 2.0 genes in this pathway
dazard对紫外线nhek的反应 244 151 All SZGR 2.0 genes in this pathway
Kaab心脏中心与心室DN 261 183 All SZGR 2.0 genes in this pathway
WELCSH BRCA1 TARGETS DN 141 92 All SZGR 2.0 genes in this pathway
Bild HRAS致癌特征 261 166 All SZGR 2.0 genes in this pathway
DOUGLAS BMI1 TARGETS UP 566 371 All SZGR 2.0 genes in this pathway
HILLION HMGA1 TARGETS 90 71 All SZGR 2.0 genes in this pathway
Dacosta UV响应通过ERCC3 common 77 47 All SZGR 2.0 genes in this pathway
Martinez RB1靶向DN 543 317 All SZGR 2.0 genes in this pathway
MARTINEZ TP53 TARGETS DN 593 372 All SZGR 2.0 genes in this pathway
MARTINEZ RB1 AND TP53 TARGETS DN 591 366 All SZGR 2.0 genes in this pathway
Ouyang前列腺癌的进展 20 14 All SZGR 2.0 genes in this pathway
GRESHOCK CANCER COPY NUMBER UP 323 240 All SZGR 2.0 genes in this pathway
Hofmann骨髓发育异常综合症低风险DN 30 20 All SZGR 2.0 genes in this pathway
Hofmann骨髓发育异常综合征风险 24 14 All SZGR 2.0 genes in this pathway
ZHAN EARLY DIFFERENTIATION GENES DN 42 29 All SZGR 2.0 genes in this pathway
MIKKELSEN ES ICP WITH H3K4ME3 718 401 All SZGR 2.0 genes in this pathway
MIKKELSEN NPC ICP WITH H3K4ME3 445 257 All SZGR 2.0 genes in this pathway
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 7 76 46 All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 1HR DN 222 147 All SZGR 2.0 genes in this pathway
WHITFIELD CELL CYCLE G1 S 147 76 All SZGR 2.0 genes in this pathway
MARTENS TRETINOIN RESPONSE UP 857 456 All SZGR 2.0 genes in this pathway
Kim所有疾病少突胶质细胞编号corr up 756 494 All SZGR 2.0 genes in this pathway
金双相情感障碍少突胶质细胞密度相关 682 440 All SZGR 2.0 genes in this pathway
KIM ALL DISORDERS DURATION CORR DN 146 90 All SZGR 2.0 genes in this pathway
棕熊UVC响应迟到 1137 655 All SZGR 2.0 genes in this pathway
BMP7的Zhang脂肪形成 14 12 All SZGR 2.0 genes in this pathway
林乳腺干细胞向上 489 314 All SZGR 2.0 genes in this pathway
SMIRNOV RESPONSE TO IR 6HR UP 166 97 All SZGR 2.0 genes in this pathway