SZGR2 - Beplay体育中心

Summary？

GeneID	3276
Symbol	PRMT1
同义词	ANM1 \| HCP1 \| HRMT1L2 \| IR1B4
描述	蛋白精氨酸甲基转移酶1
Reference	MIM：602950\|HGNC:HGNC:5187\|ENSEMBL：ENSG00000126457\|HPRD：04257\|Vega：Otthumg00000167568
Gene type	蛋白质编码
地图位置	19q13.3
Pascal P值	1.215E-5
Sherlock p-value	8.185e-5
胎儿β	0.678
主持人	尾状基底神经节 Myers' cis & trans
支持	染色质重塑基因

Gene in Data Sources

基因集名称	基因组方法	描述	信息
简历：PGCNP	全基因组协会研究	GWAS

Section I. Genetics and epigenetics annotation

EQTL注释

SNP ID	染色体	位置	主持人	Gene Entrez ID	PVALUE	QVALUE	TSS距离	eQTL type
RS443832	CHR16	83779643	PRMT1	3276		0.15		反式

第二节。转录组注释

一般基因表达（GTEX）

Devlopment期间的基因表达（BrainCloud）

Footnote:
总共绘制了269个时间点，n = 38个胎儿样品（x = 1：38）。每个三角形代表一个时间点。

时间变化的基因表达（brainspan）

Footnote:
SC：亚皮质区域；SM：感觉运动区域；FC：额叶皮层；和TP：颞顶皮层
ST1：胎儿（13-26个概念后周），ST2：婴儿早期至童年（4个月至11年）和ST3：青春期至成年期（13-23年）
所示的栏表示表达分布的较低25％和上层25％。

No co-expressed genes in brain regions

Section IV. Protein-protein interaction annotation

Interactors	Aliases B	官方全名b	实验	Source	PubMed ID
ar	AIS \| DHTR \| HUMARA \| KD \| NR3C4 \| SBMA \| SMAX1 \| TFM	androgen receptor	重构的复合物	Biogrid	11050077
arPC3	ARC21 \|p21-arc	肌动蛋白相关蛋白2/3复合物，亚基3，21KDA	Two-hybrid	Biogrid	16169070
BTG1	-	B-cell translocation gene 1, anti-proliferative	重构的复合物 Two-hybrid	Biogrid	8663146\|11856371
BTG1	-	B-cell translocation gene 1, anti-proliferative	BTG1与HRMT1L2（PRMT1）相互作用。这种相互作用是基于未指定物种的人类BTG1和PRMT1之间的相互作用进行建模的。	绑定	15674337
BTG1	-	B-cell translocation gene 1, anti-proliferative	-	HPRD	8663146\|14734530
BTG2	MGC126063 \|MGC126064 \|PC3 \|TIS21	BTG家庭，成员2	-	HPRD，Biogrid	11856371
BTG2	MGC126063 \|MGC126064 \|PC3 \|TIS21	BTG家庭，成员2	-	HPRD	8663146\|11856371\|11856371
C1orf103	FLJ11269 \| RIF1 \| RP11-96K19.1	chromosome 1 open reading frame 103	Two-hybrid	Biogrid	16169070
CAPRIN1	GPIAP1 \|GPIP137 \|M11S1 \|caprin-1 \|P137GPI	细胞周期相关蛋白1	生化活动	Biogrid	12183049
CARM1	PRMT4	coactivator-associated arginine methyltransferase 1	Phenotypic Enhancement	Biogrid	11050077
CIRBP	CIRP	冷诱导RNA结合蛋白	-	HPRD，Biogrid	11850402
DHX9	ddx9 \|LKP \|ndhii \|RHA	DEAH（ASP-GLU-ALA-HIS）盒多肽9	-	HPRD，Biogrid	11850402\|15084609
ESR1	DKFZp686N23123 \| ER \| ESR \| ESRA \| Era \| NR3A1	estrogen receptor 1	重构的复合物	Biogrid	11050077
fbl	FIB \| FLRN \| RNU3IP1	纤维林	-	HPRD，Biogrid	14583623
FUS	切碎\|FUS-CHOP \|fus1 \|TLS \|TLS/CHOP \|HNRNP-P2	融合（涉及恶性脂肪肉瘤中的t（12; 16））	-	HPRD，Biogrid	11850402
HABP4	ihabp4 \|Ki-1/57 \|MGC825 \|serbp1l	透明质酸结合蛋白4	Two-hybrid	Biogrid	16169070
HNRNPA1	HNRPA1 \|MGC102835	heterogeneous nuclear ribonucleoprotein A1	生化活动	Biogrid	8663146
hnrnpk	CSBP \|FLJ41122 \|hnrpk \|隧道	异质核核糖核蛋白K	-	HPRD，Biogrid	12529443
hnrnpr	FLJ25714 \|hnrpr \|HNRNP-R	异构核核糖核蛋白R	-	HPRD，Biogrid	12183049
hnrnpu	hnrpu \|SAF-A \|U21.1	异质核核糖核蛋白U（支架附着因子A）	-	HPRD，Biogrid	11850402
hnrnpul1	E1B-AP5 \|e1bap5 \|FLJ12944 \|HNRPUL1	异质核核糖核蛋白U样1	生化活动	Biogrid	11513728
IFNAR1	AVP \|IFN-Alpha-Rec \|ifnar \|ifnbr \|IFRC	干扰素（Alpha，beta和Omega）受体1	-	HPRD，Biogrid	9029147
IGSF21	FLJ41177 \| MGC15730	immunoglobin superfamily, member 21	Two-hybrid	Biogrid	16169070
ILF3	CBTF \|drbf \|DRBP76 \|mmp4 \|mphosph4 \|mpp4 \|NF-AT-90 \|NF110 \|NF90 \|nfar \| NFAR-1 \| NFAR2 \| TCP110 \| TCP80	interleukin enhancer binding factor 3, 90kDa	-	HPRD，Biogrid	10749851
KHDRBS1	FLJ34027 \| Sam68 \| p62	KH结构域含有RNA结合，信号转导相关1	-	HPRD，Biogrid	12529443
khdrbs3	Etle \|萨尔普\|SLM-2 \|SLM2 \|T-Star \|tstar \|etoile	KH结构域含有RNA结合，信号转导相关3	-	HPRD，Biogrid	12529443
MED31	3110004H13Rik \| CGI-125 \| FLJ27436 \| FLJ36714 \| Soh1	mediator complex subunit 31	Two-hybrid	Biogrid	16169070
NCOA1	F-SRC-1 \|kat13a \|MGC129719 \|MGC129720 \|NCOA-1 \|RIP160 \|SRC-1 \|src1 \|Bhlhe42	核受体共激活因子1	-	HPRD，Biogrid	11050077
NCOA2	GRIP1 \| KAT13C \| MGC138808 \| NCoA-2 \| TIF2	核受体共激活因子2	-	HPRD，Biogrid	11050077
NCOA3	Actr \|AIB-1 \|AIB1 \|CAGH16 \|CTG26 \|kat13b \|MGC141848 \|Rac3 \|src3 \|TNRC14 \| TNRC16 \| TRAM-1 \| pCIP	核受体共激活因子3	-	HPRD，Biogrid	11050077
PRMT1	ANM1 \|HCP1 \|HRMT1L2 \|IR1B4	蛋白精氨酸甲基转移酶1	-	HPRD，Biogrid	12737817
QKI	DKFZP586I0923 \|HQK \|QK \|qk1 \|QK3	quaking homolog, KH domain RNA binding (mouse)	-	HPRD	12529443
S100A8	60b8ag \|caga \|CFAG \|CGLA \|CP-10 \|l1ag \|MA387 \|Mif \|MRP8 \|nif \| P8	S100钙结合蛋白A8	Two-hybrid	Biogrid	16169070
SSSCA1	P27	Sjogren syndrome/scleroderma autoantigen 1	Affinity Capture-MS	Biogrid	17353931
SUPT5H	FLJ34157 \|spt5 \|SPT5H	Ty 5同源物的抑制器（S. cerevisiae）	-	HPRD，Biogrid	12718890
合并	GRY-RBP \| HNRPQ1 \| NSAP1 \| RP1-3J17.2 \| dJ3J17.2 \| hnRNP-Q \| pp68	Synaptotagmin结合，细胞质RNA相互作用蛋白	生化活动	Biogrid	12183049
TAF15	Npl3 \| RBP56 \| TAF2N \| TAFII68 \| hTAFII68	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa	生化活动	Biogrid	12183049
THRB	ERBA-BETA \| ERBA2 \| GRTH \| MGC126109 \| MGC126110 \| NR1A2 \| PRTH \| THR1 \| THRB1 \| THRB2	甲状腺激素受体，β（红细胞白血病病毒（V-ERB-A）癌基因同源物2，Avian）	重构的复合物	Biogrid	11050077
TP53	FLJ92943 \| LFS1 \| TRP53 \| p53	肿瘤蛋白p53	-	HPRD，Biogrid	15186775
TP53	FLJ92943 \| LFS1 \| TRP53 \| p53	肿瘤蛋白p53	PRMT1interacts with p53. This interaction was modeled on a demonstrated interaction between rat PRMT1 and human p53.	绑定	15186775
WDR33	FLJ11294 \| WDC146	WD repeat domain 33	Two-hybrid	Biogrid	16169070
YLPM1	C14orf170 \| ZAP \| ZAP3	包含1的YLP图案	Two-hybrid	Biogrid	16169070
ZFP161	MGC126126 \|ZBTB14 \|ZF5 \|ZNF478	锌指蛋白161同源物（小鼠）	生化活动	Biogrid	12183049

Section V. Pathway annotation

路径名	通路size	# SZGR 2.0 genes in pathway	信息
PID P53 DOWNSTREAM PATHWAY	137	94	All SZGR 2.0 genes in this pathway
LIU SOX4 TARGETS DN	309	191	All SZGR 2.0 genes in this pathway
迪亚兹慢性巨态性白血病	1382	904	All SZGR 2.0 genes in this pathway
deurig t细胞促进性白血病	368	234	All SZGR 2.0 genes in this pathway
VECCHI GASTRIC CANCER EARLY UP	430	232	All SZGR 2.0 genes in this pathway
莱茵所有糖皮质激素治疗DN	362	238	All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA DN	1375	806	All SZGR 2.0 genes in this pathway
hahtola兄弟姐妹fungoides DN	16	10	All SZGR 2.0 genes in this pathway
Provenzani转移DN	136	94	All SZGR 2.0 genes in this pathway
SCHLOSSER MYC TARGETS AND SERUM RESPONSE UP	47	32	All SZGR 2.0 genes in this pathway
Mohankumar TLX1靶向	414	287	All SZGR 2.0 genes in this pathway
TSAI RESPONSE TO IONIZING RADIATION	149	101	All SZGR 2.0 genes in this pathway
PUJANA BRCA1 PCC网络	1652	1023	All SZGR 2.0 genes in this pathway
PUJANA CHEK2 PCC NETWORK	779	480	All SZGR 2.0 genes in this pathway
NUYTTEN EZH2 TARGETS DN	1024	594	All SZGR 2.0 genes in this pathway
带有E盒的WEI MYCN目标	795	478	All SZGR 2.0 genes in this pathway
里克曼肿瘤分化中等程度与不良	121	71	All SZGR 2.0 genes in this pathway
Schaeffer前列腺开发12小时DN	57	45	All SZGR 2.0 genes in this pathway
Peng Leucine剥夺DN	187	122	All SZGR 2.0 genes in this pathway
Flechner PBL肾脏移植OK vs捐助者	151	100	All SZGR 2.0 genes in this pathway
SANA RESPONSE TO IFNG DN	85	56	All SZGR 2.0 genes in this pathway
彭雷帕霉素反应dn	245	154	All SZGR 2.0 genes in this pathway
PENG GLUTAMINE DEPRIVATION DN	337	230	All SZGR 2.0 genes in this pathway
MATSUDA NATURAL KILLER DIFFERENTIATION	475	313	All SZGR 2.0 genes in this pathway
HOXA9和MEIS1的赫斯目标	65	44	All SZGR 2.0 genes in this pathway
Xu Crebbp目标	26	16	All SZGR 2.0 genes in this pathway
XU RESPONSE TO TRETINOIN AND NSC682994 DN	15	12	All SZGR 2.0 genes in this pathway
阿尔茨海默氏病dn	1237	837	All SZGR 2.0 genes in this pathway
RAMASWAMY METASTASIS UP	66	43	All SZGR 2.0 genes in this pathway
Krige对Tosedostat 6小时的反应	953	554	All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 24HR DN	1011	592	All SZGR 2.0 genes in this pathway
Kyng DNA损坏4NQO或UV	63	44	All SZGR 2.0 genes in this pathway
Kyng DNA损伤DN	195	135	All SZGR 2.0 genes in this pathway
Stearman肺癌早期与晚期	125	89	All SZGR 2.0 genes in this pathway
Rizki肿瘤侵入性3D DN	270	181	All SZGR 2.0 genes in this pathway
等级转移DN	45	31	All SZGR 2.0 genes in this pathway
Labbe Wnt3a靶向	112	71	All SZGR 2.0 genes in this pathway
LEE LIVER CANCER SURVIVAL DN	175	103	All SZGR 2.0 genes in this pathway
Aguirre胰腺癌复制号	298	174	All SZGR 2.0 genes in this pathway
LEE RECENT THYMIC EMIGRANT	227	128	All SZGR 2.0 genes in this pathway
Shedden肺癌的生存率差A6	456	285	All SZGR 2.0 genes in this pathway
CAIRO HEPATOBLASTOMA CLASSES UP	605	377	All SZGR 2.0 genes in this pathway
WONG EMBRYONIC STEM CELL CORE	335	193	All SZGR 2.0 genes in this pathway
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 14	143	86	All SZGR 2.0 genes in this pathway
MARTENS TRETINOIN RESPONSE DN	841	431	All SZGR 2.0 genes in this pathway
Lee BMP2靶向DN	882	538	All SZGR 2.0 genes in this pathway

基因页：PRMT1